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The map label for this gene is murB [H]

Identifier: 91787481

GI number: 91787481

Start: 1648864

End: 1649931

Strand: Direct

Name: murB [H]

Synonym: Bpro_1597

Alternate gene names: 91787481

Gene position: 1648864-1649931 (Clockwise)

Preceding gene: 91787478

Following gene: 91787482

Centisome position: 31.71

GC content: 63.3

Gene sequence:

>1068_bases
GTGATGTTAGTCGAGAAAAACGTTCCGCTCCAGCATTCCAACAGCTTTGGCATTATGGCCAAGGCGCTTTCCCTCGTCCG
GGTCAGTGCCGAGTCCGACATTGCCGCCGTGCTGCAGGATGATGCGTTGCGCGCCATGTCCAAGTTTGTGCTGGGCGGTG
GCAGCAACATCGTGCTGACCGGTGACGTCAAACCCCTGGTGCTCAAGGTGGAGATCATGGGCAAGCGCCTGGTCGGCGAA
ACCGCCAAGGCCTGGATCGTCGAGGCCGGGGCTGGCGAGAACTGGCACGATCTGGTCACCTGGACCCTGCAGATGGGCTA
CCCGGGCCTGGAAAACCTGGCACTGATCCCCGGCACCGTCGGCGCATCGCCTGTGCAGAACATTGGCGCCTATGGGGTGG
AGCTGCAGGACCGCTTCGAGTCGCTCGATGCCGTGGACCTGACCACCGGCCAGCGCTTTACCCTCAATGCCGCGCAGTGC
GCGTTCGGCTACCGCGATTCCGTGTTCAAACACACCAGCATCGCCACCAGTGCGGGCACGCCCGGTTTCGGCTTGGCGGG
CAAGGCGCTGATCACCCATGTGCGGTTTTCCCTGCCCAAGGCCTGGAAGGCCGTGCTGGGGTATGCCGATATCGAGAAAA
AGATGCAGCAGGCCGGGGTCCATGCGCCGGATGCGCAGCAAATTTACGACTGGATTTGCGAAATCCGCCGGGCCAAGCTG
CCCGATCCGCAGGTCATCGGCAATGCCGGCAGCTTCTTCAAGAACCCGACCGTTTCACCCGAGCAGTGCGCCGACATCAT
CCAGCGCGAGCCCAAAATTGTTCACTACCCGCTGGCCGACGGCACGGTCAAGCTGGCCGCAGGCTGGCTCATCGACGCCT
GCGGCTGGAAAGGCAAATCCGTAGGCAATGCCGGCGTGTACGACAGGCAGGCACTGGTGCTGGTGAACCGCGGCGGCCCC
GGCAACCCGGTGACGGGCGGTGAAGTGATGACCCTGGCCAAGGCCATCCAGACCAGCGTGTACGAACGTTTTGGCATCCT
GCTGGAGCCCGAGCCGGTGGTGGTCTGA

Upstream 100 bases:

>100_bases
CTGGAAGTAAGAGAAAAGGACAGGTGAAAAAGGGGGGCGTAGAGGGCGGTAAAAGGGCGGGAAGAGGTGGGGCAGGGGCG
GGCAGGGATGAGACAATCCC

Downstream 100 bases:

>100_bases
TGGACCTTTTCCATCTGAATTTCCGCCGCCGCATCAACGCGCTCGTGTGGGCGCGGCGCGCGGTGGTGCTGGCCGCGGTG
CTCGCGGTATGGGTCTGGCA

Product: UDP-N-acetylmuramate dehydrogenase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MMLVEKNVPLQHSNSFGIMAKALSLVRVSAESDIAAVLQDDALRAMSKFVLGGGSNIVLTGDVKPLVLKVEIMGKRLVGE
TAKAWIVEAGAGENWHDLVTWTLQMGYPGLENLALIPGTVGASPVQNIGAYGVELQDRFESLDAVDLTTGQRFTLNAAQC
AFGYRDSVFKHTSIATSAGTPGFGLAGKALITHVRFSLPKAWKAVLGYADIEKKMQQAGVHAPDAQQIYDWICEIRRAKL
PDPQVIGNAGSFFKNPTVSPEQCADIIQREPKIVHYPLADGTVKLAAGWLIDACGWKGKSVGNAGVYDRQALVLVNRGGP
GNPVTGGEVMTLAKAIQTSVYERFGILLEPEPVVV

Sequences:

>Translated_355_residues
MMLVEKNVPLQHSNSFGIMAKALSLVRVSAESDIAAVLQDDALRAMSKFVLGGGSNIVLTGDVKPLVLKVEIMGKRLVGE
TAKAWIVEAGAGENWHDLVTWTLQMGYPGLENLALIPGTVGASPVQNIGAYGVELQDRFESLDAVDLTTGQRFTLNAAQC
AFGYRDSVFKHTSIATSAGTPGFGLAGKALITHVRFSLPKAWKAVLGYADIEKKMQQAGVHAPDAQQIYDWICEIRRAKL
PDPQVIGNAGSFFKNPTVSPEQCADIIQREPKIVHYPLADGTVKLAAGWLIDACGWKGKSVGNAGVYDRQALVLVNRGGP
GNPVTGGEVMTLAKAIQTSVYERFGILLEPEPVVV
>Mature_355_residues
MMLVEKNVPLQHSNSFGIMAKALSLVRVSAESDIAAVLQDDALRAMSKFVLGGGSNIVLTGDVKPLVLKVEIMGKRLVGE
TAKAWIVEAGAGENWHDLVTWTLQMGYPGLENLALIPGTVGASPVQNIGAYGVELQDRFESLDAVDLTTGQRFTLNAAQC
AFGYRDSVFKHTSIATSAGTPGFGLAGKALITHVRFSLPKAWKAVLGYADIEKKMQQAGVHAPDAQQIYDWICEIRRAKL
PDPQVIGNAGSFFKNPTVSPEQCADIIQREPKIVHYPLADGTVKLAAGWLIDACGWKGKSVGNAGVYDRQALVLVNRGGP
GNPVTGGEVMTLAKAIQTSVYERFGILLEPEPVVV

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=345, Percent_Identity=43.4782608695652, Blast_Score=267, Evalue=7e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37993; Mature: 37993

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLVEKNVPLQHSNSFGIMAKALSLVRVSAESDIAAVLQDDALRAMSKFVLGGGSNIVLT
CEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
GDVKPLVLKVEIMGKRLVGETAKAWIVEAGAGENWHDLVTWTLQMGYPGLENLALIPGTV
CCCCEEEEEEEECCCHHHCCCCEEEEEECCCCCCCHHEEEEEEECCCCCCCCCEECCCCC
GASPVQNIGAYGVELQDRFESLDAVDLTTGQRFTLNAAQCAFGYRDSVFKHTSIATSAGT
CCCHHHHHCCCCCCHHHHHCCCCEEEECCCCEEEEEHHHHHCCCHHHHHHHHEEECCCCC
PGFGLAGKALITHVRFSLPKAWKAVLGYADIEKKMQQAGVHAPDAQQIYDWICEIRRAKL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
PDPQVIGNAGSFFKNPTVSPEQCADIIQREPKIVHYPLADGTVKLAAGWLIDACGWKGKS
CCCCEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEECEEEECCCCCCCC
VGNAGVYDRQALVLVNRGGPGNPVTGGEVMTLAKAIQTSVYERFGILLEPEPVVV
CCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCC
>Mature Secondary Structure
MMLVEKNVPLQHSNSFGIMAKALSLVRVSAESDIAAVLQDDALRAMSKFVLGGGSNIVLT
CEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
GDVKPLVLKVEIMGKRLVGETAKAWIVEAGAGENWHDLVTWTLQMGYPGLENLALIPGTV
CCCCEEEEEEEECCCHHHCCCCEEEEEECCCCCCCHHEEEEEEECCCCCCCCCEECCCCC
GASPVQNIGAYGVELQDRFESLDAVDLTTGQRFTLNAAQCAFGYRDSVFKHTSIATSAGT
CCCHHHHHCCCCCCHHHHHCCCCEEEECCCCEEEEEHHHHHCCCHHHHHHHHEEECCCCC
PGFGLAGKALITHVRFSLPKAWKAVLGYADIEKKMQQAGVHAPDAQQIYDWICEIRRAKL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
PDPQVIGNAGSFFKNPTVSPEQCADIIQREPKIVHYPLADGTVKLAAGWLIDACGWKGKS
CCCCEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEECEEEECCCCCCCC
VGNAGVYDRQALVLVNRGGPGNPVTGGEVMTLAKAIQTSVYERFGILLEPEPVVV
CCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA