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The map label for this gene is hutI

Identifier: 91786934

GI number: 91786934

Start: 1061850

End: 1063127

Strand: Reverse

Name: hutI

Synonym: Bpro_1035

Alternate gene names: 91786934

Gene position: 1063127-1061850 (Counterclockwise)

Preceding gene: 91786935

Following gene: 91786933

Centisome position: 20.44

GC content: 70.66

Gene sequence:

>1278_bases
ATGACCACAGCCCCCCACCCCGCTGCCGACGGCATCTGGGAGCATTTGCGCCTGATGCCTGGCGCGCTGGCCGACGACAG
CCCCGTGGCGACGAACACCGAGGCCGCCATCGTCGTCACCGAAGGCCGGATCCGCTGGATAGGCGCCAGCGCCGCGCTGC
CCGCCGGGTTCAGCGCGCTGCCGCGTTTTGACGGCGGCGGCGCGCTGGTGACGCCCGGCCTGGTCGATTGCCATACCCAT
CTGGTGTACGGTGGCCAGCGCGCCAACGAGTTCGCCATGCGGCTGGCCGGTGCCAGCTATGAAGAGGTGGCGAAGGCCGG
CGGCGGCATCGTCTCCAGCGTGCGCGCCACCCGTGCGGCCGGTGAAGACGAGCTTTTTGCGCAGGCCGCGCCTCGCCTGG
AACAACTGCTGGCCGATGGCGTGTGCGCCATCGAAATCAAGTCCGGCTATGGTCTCGCCCTCGAACACGAGCGCAAGCAG
CTGCGCGTGGCGCGCCGGCTCGGTGAGGCCTACGGCGTCACCGTGCGCACCACCTTCCTCGGCGCGCACGCACTGCCGCC
CGAGTACGCGGGCCGCAGCCAGGACTACATCGACCTGGTCTGCCGCGAGATGCTGCCCGCACTCGCCGCCGAAGGCCTGG
TCGATGCGGTGGACGTATTTTGCGAACGCATCGCGTTTTCGCTGAGCGAGACCGAGCAGGTGTTCCAGGCCGCGCAGCGT
TTAGGCCTGCCGGTCAAGCTGCATGCCGAGCAGCTCTCCGACATGGGCGGCGCCGCGCTCGCCGCGCGTTATGGCGCGCT
GTCGTGCGACCACATCGAACACCTGTCGCAGGCCGGCATCGACGCCATGCGCGCGGCCGGCACGGTGGCCGTGCTGCTGC
CCGGCGCCTACTACACGCTGCGCGACACCCACCTGCCACCGATCGCCGCGCTGCGCGAAGCCGGCGTGCCCATGGCCGTC
TCGACCGACCACAACCCCGGCACGTCGCCCGCGCTCAGCCTGCTGCTCATGGCCAACATGGCCTGCACACTGTTTCGCCT
GACCGTGCCGGAAGCGCTGGCCGGCATCACGCGCCACGCAGCCCGTGCGCTCGGACTGCAGGACACGCACGGCGCACTCG
GCGTGGGCCGGCCCGCCAATTTCGTGCTGTGGCAGCTGAATGACAGCGCCGAGCTGGCCTACTGGCTGGGCCAGCAGGCG
CCGCGCACCATCGTGCGGCAGGGGCGCGTTGCGCTCGACGGGCTCCAGATCGCCCCCAACGCCAGGATCACCCCATGA

Upstream 100 bases:

>100_bases
ATGGCCTCTGGTCCATGTCAAAACCTAACGATCAGCTATTTACTCAATAGCAAAACAAGCCTCTGCACATAACCCCCTCA
TAACCCCGCCAGTGAACCCC

Downstream 100 bases:

>100_bases
GCGACATCGCCCCCTTCGCTGCCCCGACATCCCATGCCCCAGCCATGGGCAGCCTGTTTGCCACCGATGCCCTGCTGCCC
GACGGCTGGGCGCGCAACGT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTTAPHPAADGIWEHLRLMPGALADDSPVATNTEAAIVVTEGRIRWIGASAALPAGFSALPRFDGGGALVTPGLVDCHTH
LVYGGQRANEFAMRLAGASYEEVAKAGGGIVSSVRATRAAGEDELFAQAAPRLEQLLADGVCAIEIKSGYGLALEHERKQ
LRVARRLGEAYGVTVRTTFLGAHALPPEYAGRSQDYIDLVCREMLPALAAEGLVDAVDVFCERIAFSLSETEQVFQAAQR
LGLPVKLHAEQLSDMGGAALAARYGALSCDHIEHLSQAGIDAMRAAGTVAVLLPGAYYTLRDTHLPPIAALREAGVPMAV
STDHNPGTSPALSLLLMANMACTLFRLTVPEALAGITRHAARALGLQDTHGALGVGRPANFVLWQLNDSAELAYWLGQQA
PRTIVRQGRVALDGLQIAPNARITP

Sequences:

>Translated_425_residues
MTTAPHPAADGIWEHLRLMPGALADDSPVATNTEAAIVVTEGRIRWIGASAALPAGFSALPRFDGGGALVTPGLVDCHTH
LVYGGQRANEFAMRLAGASYEEVAKAGGGIVSSVRATRAAGEDELFAQAAPRLEQLLADGVCAIEIKSGYGLALEHERKQ
LRVARRLGEAYGVTVRTTFLGAHALPPEYAGRSQDYIDLVCREMLPALAAEGLVDAVDVFCERIAFSLSETEQVFQAAQR
LGLPVKLHAEQLSDMGGAALAARYGALSCDHIEHLSQAGIDAMRAAGTVAVLLPGAYYTLRDTHLPPIAALREAGVPMAV
STDHNPGTSPALSLLLMANMACTLFRLTVPEALAGITRHAARALGLQDTHGALGVGRPANFVLWQLNDSAELAYWLGQQA
PRTIVRQGRVALDGLQIAPNARITP
>Mature_424_residues
TTAPHPAADGIWEHLRLMPGALADDSPVATNTEAAIVVTEGRIRWIGASAALPAGFSALPRFDGGGALVTPGLVDCHTHL
VYGGQRANEFAMRLAGASYEEVAKAGGGIVSSVRATRAAGEDELFAQAAPRLEQLLADGVCAIEIKSGYGLALEHERKQL
RVARRLGEAYGVTVRTTFLGAHALPPEYAGRSQDYIDLVCREMLPALAAEGLVDAVDVFCERIAFSLSETEQVFQAAQRL
GLPVKLHAEQLSDMGGAALAARYGALSCDHIEHLSQAGIDAMRAAGTVAVLLPGAYYTLRDTHLPPIAALREAGVPMAVS
TDHNPGTSPALSLLLMANMACTLFRLTVPEALAGITRHAARALGLQDTHGALGVGRPANFVLWQLNDSAELAYWLGQQAP
RTIVRQGRVALDGLQIAPNARITP

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=369, Percent_Identity=37.3983739837398, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17555004, Length=409, Percent_Identity=33.9853300733496, Blast_Score=227, Evalue=7e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_POLSJ (Q12EQ4)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_547886.1
- ProteinModelPortal:   Q12EQ4
- SMR:   Q12EQ4
- STRING:   Q12EQ4
- GeneID:   4012156
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_1035
- NMPDR:   fig|296591.1.peg.3371
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   PSP296591:BPRO_1035-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR013108
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF07969 Amidohydro_3; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 44820; Mature: 44689

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: BINDING 87-87 BINDING 100-100 BINDING 150-150 BINDING 183-183 BINDING 251-251

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAPHPAADGIWEHLRLMPGALADDSPVATNTEAAIVVTEGRIRWIGASAALPAGFSAL
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCHHC
PRFDGGGALVTPGLVDCHTHLVYGGQRANEFAMRLAGASYEEVAKAGGGIVSSVRATRAA
CCCCCCCCEECCCHHHHHHHEEECCCCHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCC
GEDELFAQAAPRLEQLLADGVCAIEIKSGYGLALEHERKQLRVARRLGEAYGVTVRTTFL
CCHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCEEEEEEEC
GAHALPPEYAGRSQDYIDLVCREMLPALAAEGLVDAVDVFCERIAFSLSETEQVFQAAQR
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLPVKLHAEQLSDMGGAALAARYGALSCDHIEHLSQAGIDAMRAAGTVAVLLPGAYYTL
HCCCEEEEHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCHHHHHHCCEEEEEECCCEEEE
RDTHLPPIAALREAGVPMAVSTDHNPGTSPALSLLLMANMACTLFRLTVPEALAGITRHA
ECCCCCHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARALGLQDTHGALGVGRPANFVLWQLNDSAELAYWLGQQAPRTIVRQGRVALDGLQIAPN
HHHCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCHHHHHHCCCEEECCEEECCC
ARITP
CCCCC
>Mature Secondary Structure 
TTAPHPAADGIWEHLRLMPGALADDSPVATNTEAAIVVTEGRIRWIGASAALPAGFSAL
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCHHC
PRFDGGGALVTPGLVDCHTHLVYGGQRANEFAMRLAGASYEEVAKAGGGIVSSVRATRAA
CCCCCCCCEECCCHHHHHHHEEECCCCHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCC
GEDELFAQAAPRLEQLLADGVCAIEIKSGYGLALEHERKQLRVARRLGEAYGVTVRTTFL
CCHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCEEEEEEEC
GAHALPPEYAGRSQDYIDLVCREMLPALAAEGLVDAVDVFCERIAFSLSETEQVFQAAQR
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLPVKLHAEQLSDMGGAALAARYGALSCDHIEHLSQAGIDAMRAAGTVAVLLPGAYYTL
HCCCEEEEHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCHHHHHHCCEEEEEECCCEEEE
RDTHLPPIAALREAGVPMAVSTDHNPGTSPALSLLLMANMACTLFRLTVPEALAGITRHA
ECCCCCHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARALGLQDTHGALGVGRPANFVLWQLNDSAELAYWLGQQAPRTIVRQGRVALDGLQIAPN
HHHCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCHHHHHHCCCEEECCEEECCC
ARITP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA