Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 91786901

GI number: 91786901

Start: 1016802

End: 1018151

Strand: Reverse

Name: trpS [H]

Synonym: Bpro_1001

Alternate gene names: 91786901

Gene position: 1018151-1016802 (Counterclockwise)

Preceding gene: 91786902

Following gene: 91786900

Centisome position: 19.58

GC content: 64.44

Gene sequence:

>1350_bases
ATGATGACAAACCCAACAACTGACGCCGGCGCGCGTTCTACCCCTGACGCCTCACCACAGAGGTTCCTGACCGGCATCAC
CACCACGGGTACGCCCCACCTGGGCAACTTCGTGGGCTCGATCCGGCCGTCGGTGGCCGCCAGCCGCTTGCCTCACGTGC
AAAGTTTTTACTTCCTGGCCGACTACCATGCACTGATCAAGTGCGATGAGCCCGCGCGCATCCAGCGCTCCACACTGGAG
ATTGCCGCCAGCTGGCTGGCCGCCGGGCTGGATCCGGAGCGCGTGACGTTTTACCGCCAGTCCGACATTCCGGAAATTCC
CGAGCTCACCTGGCTGCTGACCTGCGTCACCGGCAAGGGCGTGCTGAACCGGGCCCATGCCTACAAGGCCTCGGTCGACA
AGAACACGGCGGCCGGCATTGACCCGGATGCCGATGTCACGGCGGGCCTGTTCATGTACCCGGTGCTCATGGGCGCCGAC
ATCCTGATGTTCAAGACGCACAAGGTGCCGGTGGGGCGCGACCAGATCCAGCACATCGAGATGGCGCGCGACATGGCGCA
GCGCTTCAACCATCTGTACGGCGAGCACCTGGTGTTGCCGGAAGCGGTGATTGAAGAATCCGTGGCCCTGTTGCCGGGCC
TGGACGGGCGCAAGATGAGCAAGAGCTACGACAACACCATTCCCCTGTTCACGCCGCGCGAGCAGCTGCGCAAGGCGATC
AGCGGCATCGTGACCGACTCGCGCGCGCCGGGCGAGCCCAAGGACGTCGAAGGCTCCGCGCTGTTCCAGATTTACCAGGC
GTTTGCCAGCGCGGACGAGACAGCCGCGATGCGCCAGGCCTATGCCGACGGCATTGCCTGGGGCGATGCCAAGCAGATGC
TTTTTGAGCGCATTGACCGCGAAGTGGCGCCCATGCGCGAACAGTATCTGGCGCTGATCAACGATGCCGGCCGCCTCGAA
GCCGTGCTGCTGGCTGGCGCCGAGAAAGCCCGCGCCGTGGCAAAACCATTCATGGCCGAGCTGCGCCAGGCAGTGGGGCT
GCGCAGCCTGGGCTCAGGCGCGGTGGCCGCCCCCAAACACAAAGCGGCCAGGACTGCTGCGCCAGCCTTCAAGCAGTACC
GCGAAAAGGACGGCCGGTTTTATTTCAAGCTGCTGGACGCCGATGCCCGCCTGCTGCTGCAAAGCCAGGGTTTTGATTCG
CCGCGTGACGCAGCGCAAGCCATTGCAGCCCTGCAAAAAGAAGGCCCTGCCGCACTGCCCGCGCTCCAGGACAAGGTCGC
CGCCGCACCCGAAATTTCTGCCAGTGACGTGGCTGCAGCTTTGCATTTTTTCGCGGCTATCGCGCACTGA

Upstream 100 bases:

>100_bases
TTGCCGGCGTGATCAGCAATCTCTGGATGCGCCCGCTGATGGCGCTGACCTACACCTTTCTGGAAACCGTGTTGATGCCC
CTGGCCATGCTGGTGCGATG

Downstream 100 bases:

>100_bases
ATACCGAAGACGCGGGGACCAGGACGGCCAGCGAGGCGTTGCGCCTCACCGCCTGCCGGACGGCAGAAATCGGACATTGC
CGTGACCGCCCAAAAAGAAA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MMTNPTTDAGARSTPDASPQRFLTGITTTGTPHLGNFVGSIRPSVAASRLPHVQSFYFLADYHALIKCDEPARIQRSTLE
IAASWLAAGLDPERVTFYRQSDIPEIPELTWLLTCVTGKGVLNRAHAYKASVDKNTAAGIDPDADVTAGLFMYPVLMGAD
ILMFKTHKVPVGRDQIQHIEMARDMAQRFNHLYGEHLVLPEAVIEESVALLPGLDGRKMSKSYDNTIPLFTPREQLRKAI
SGIVTDSRAPGEPKDVEGSALFQIYQAFASADETAAMRQAYADGIAWGDAKQMLFERIDREVAPMREQYLALINDAGRLE
AVLLAGAEKARAVAKPFMAELRQAVGLRSLGSGAVAAPKHKAARTAAPAFKQYREKDGRFYFKLLDADARLLLQSQGFDS
PRDAAQAIAALQKEGPAALPALQDKVAAAPEISASDVAAALHFFAAIAH

Sequences:

>Translated_449_residues
MMTNPTTDAGARSTPDASPQRFLTGITTTGTPHLGNFVGSIRPSVAASRLPHVQSFYFLADYHALIKCDEPARIQRSTLE
IAASWLAAGLDPERVTFYRQSDIPEIPELTWLLTCVTGKGVLNRAHAYKASVDKNTAAGIDPDADVTAGLFMYPVLMGAD
ILMFKTHKVPVGRDQIQHIEMARDMAQRFNHLYGEHLVLPEAVIEESVALLPGLDGRKMSKSYDNTIPLFTPREQLRKAI
SGIVTDSRAPGEPKDVEGSALFQIYQAFASADETAAMRQAYADGIAWGDAKQMLFERIDREVAPMREQYLALINDAGRLE
AVLLAGAEKARAVAKPFMAELRQAVGLRSLGSGAVAAPKHKAARTAAPAFKQYREKDGRFYFKLLDADARLLLQSQGFDS
PRDAAQAIAALQKEGPAALPALQDKVAAAPEISASDVAAALHFFAAIAH
>Mature_449_residues
MMTNPTTDAGARSTPDASPQRFLTGITTTGTPHLGNFVGSIRPSVAASRLPHVQSFYFLADYHALIKCDEPARIQRSTLE
IAASWLAAGLDPERVTFYRQSDIPEIPELTWLLTCVTGKGVLNRAHAYKASVDKNTAAGIDPDADVTAGLFMYPVLMGAD
ILMFKTHKVPVGRDQIQHIEMARDMAQRFNHLYGEHLVLPEAVIEESVALLPGLDGRKMSKSYDNTIPLFTPREQLRKAI
SGIVTDSRAPGEPKDVEGSALFQIYQAFASADETAAMRQAYADGIAWGDAKQMLFERIDREVAPMREQYLALINDAGRLE
AVLLAGAEKARAVAKPFMAELRQAVGLRSLGSGAVAAPKHKAARTAAPAFKQYREKDGRFYFKLLDADARLLLQSQGFDS
PRDAAQAIAALQKEGPAALPALQDKVAAAPEISASDVAAALHFFAAIAH

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=339, Percent_Identity=31.2684365781711, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI41352700, Length=193, Percent_Identity=37.8238341968912, Blast_Score=142, Evalue=6e-34,
Organism=Escherichia coli, GI1789786, Length=335, Percent_Identity=35.2238805970149, Blast_Score=171, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI71982800, Length=355, Percent_Identity=31.2676056338028, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71982793, Length=355, Percent_Identity=31.5492957746479, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320474, Length=347, Percent_Identity=30.835734870317, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24666151, Length=364, Percent_Identity=31.043956043956, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR010879
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 48682; Mature: 48682

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTNPTTDAGARSTPDASPQRFLTGITTTGTPHLGNFVGSIRPSVAASRLPHVQSFYFLA
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHCCHHHHHHHHH
DYHALIKCDEPARIQRSTLEIAASWLAAGLDPERVTFYRQSDIPEIPELTWLLTCVTGKG
HHHHEEECCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCHHHHHHHHHCCCH
VLNRAHAYKASVDKNTAAGIDPDADVTAGLFMYPVLMGADILMFKTHKVPVGRDQIQHIE
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHH
MARDMAQRFNHLYGEHLVLPEAVIEESVALLPGLDGRKMSKSYDNTIPLFTPREQLRKAI
HHHHHHHHHHHHHCCCEECHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHH
SGIVTDSRAPGEPKDVEGSALFQIYQAFASADETAAMRQAYADGIAWGDAKQMLFERIDR
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EVAPMREQYLALINDAGRLEAVLLAGAEKARAVAKPFMAELRQAVGLRSLGSGAVAAPKH
HHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCH
KAARTAAPAFKQYREKDGRFYFKLLDADARLLLQSQGFDSPRDAAQAIAALQKEGPAALP
HHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCH
ALQDKVAAAPEISASDVAAALHFFAAIAH
HHHHHHHCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMTNPTTDAGARSTPDASPQRFLTGITTTGTPHLGNFVGSIRPSVAASRLPHVQSFYFLA
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHCCHHHHHHHHH
DYHALIKCDEPARIQRSTLEIAASWLAAGLDPERVTFYRQSDIPEIPELTWLLTCVTGKG
HHHHEEECCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCHHHHHHHHHCCCH
VLNRAHAYKASVDKNTAAGIDPDADVTAGLFMYPVLMGADILMFKTHKVPVGRDQIQHIE
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHH
MARDMAQRFNHLYGEHLVLPEAVIEESVALLPGLDGRKMSKSYDNTIPLFTPREQLRKAI
HHHHHHHHHHHHHCCCEECHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHH
SGIVTDSRAPGEPKDVEGSALFQIYQAFASADETAAMRQAYADGIAWGDAKQMLFERIDR
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EVAPMREQYLALINDAGRLEAVLLAGAEKARAVAKPFMAELRQAVGLRSLGSGAVAAPKH
HHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCH
KAARTAAPAFKQYREKDGRFYFKLLDADARLLLQSQGFDSPRDAAQAIAALQKEGPAALP
HHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCH
ALQDKVAAAPEISASDVAAALHFFAAIAH
HHHHHHHCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]