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The map label for this gene is pheA [H]

Identifier: 91786871

GI number: 91786871

Start: 988621

End: 989463

Strand: Reverse

Name: pheA [H]

Synonym: Bpro_0969

Alternate gene names: 91786871

Gene position: 989463-988621 (Counterclockwise)

Preceding gene: 91786872

Following gene: 91786870

Centisome position: 19.03

GC content: 51.25

Gene sequence:

>843_bases
ATGCGAATTGCTGCAGCAAATTTGATCGCTTGCCTGGGACCTGTAGGCACCTATAGTGAAGATGCTGCGATCCTGTATTT
CGGATCGAGTAGCAAACGCCTGTTGTTACCTTCGCTGGATGCCATATTCGAAGCGTGCGAATCGGGATTGGCTAGCCACA
GTGTCGTAGCTGTTGAGAACAGCACGGAGGGAGCCGTTCCAAGGACCCTTGATCTTTTATATAAAACAGAGCTTCAAATA
TGCGGTGAATTGTCGCTGTTACTGCGACATGATCTTTTAACGCAATCTGGACAGCTCCATGGTGTTACTCGTGTTCGCGC
ACACGCACAGGCGCTTGCGCAGTGTCATGGATGGTTGTCCACGAATGCGCCACACTTGATACGAGAAGCGGTGTCAAGTA
ATGCGGAAGGCGCAAGGCTTGCAGCCCAGGACCCAACCTCTGCTGCGATTGGCGGTCTGAGATCGGCTGAGGAATACGGA
CTATTGGCTGCCTTTCATGCCGTTCAGGACGATCCGAATAATCGCACCCGATTTTTTGTTTTAAGTCGCAAAGACAACGC
ATCAGAAGCTCTCGGGGTCGGGTGTAAGACATCAATCATTGTGTCGGTGCCGAATGAGGTGGGCGCTCTTTTCCGTGTGG
TTGAGCCTTTCGCTCGACATGGTGTCTCGATGTCCAGGTTTGAGTCGCGGCCTGTCAAGTCGGGGGCTTGGGACTACAAC
TTCTATATAGATATCGTTGGTAGTCGTTTGGAGGAGAAAGTGGCGAATGCGCTCGCTGAACTTCAGCAACAGGGAGCAAA
AGTGAAGTTACTAGGCTCTTACTTCGACACGGATCAACATTGA

Upstream 100 bases:

>100_bases
CCCTGCCATCCCCATGATTAACGTATCCGATATCAACAAGCCCGCACCCGTTGGCCGGCTCAGAGCCGCTTCATTGGGAA
CGGACATCGACCATGGGCAA

Downstream 100 bases:

>100_bases
TCTGATAAGGCGTTTTCCATCTCAGCGCCTCGAGATGTTTGGCAAAGTTGAAGGCGCAGACAAAGGCCAACACATGTGCT
TTCAGGCTCTCCAAGTCGGG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MRIAAANLIACLGPVGTYSEDAAILYFGSSSKRLLLPSLDAIFEACESGLASHSVVAVENSTEGAVPRTLDLLYKTELQI
CGELSLLLRHDLLTQSGQLHGVTRVRAHAQALAQCHGWLSTNAPHLIREAVSSNAEGARLAAQDPTSAAIGGLRSAEEYG
LLAAFHAVQDDPNNRTRFFVLSRKDNASEALGVGCKTSIIVSVPNEVGALFRVVEPFARHGVSMSRFESRPVKSGAWDYN
FYIDIVGSRLEEKVANALAELQQQGAKVKLLGSYFDTDQH

Sequences:

>Translated_280_residues
MRIAAANLIACLGPVGTYSEDAAILYFGSSSKRLLLPSLDAIFEACESGLASHSVVAVENSTEGAVPRTLDLLYKTELQI
CGELSLLLRHDLLTQSGQLHGVTRVRAHAQALAQCHGWLSTNAPHLIREAVSSNAEGARLAAQDPTSAAIGGLRSAEEYG
LLAAFHAVQDDPNNRTRFFVLSRKDNASEALGVGCKTSIIVSVPNEVGALFRVVEPFARHGVSMSRFESRPVKSGAWDYN
FYIDIVGSRLEEKVANALAELQQQGAKVKLLGSYFDTDQH
>Mature_280_residues
MRIAAANLIACLGPVGTYSEDAAILYFGSSSKRLLLPSLDAIFEACESGLASHSVVAVENSTEGAVPRTLDLLYKTELQI
CGELSLLLRHDLLTQSGQLHGVTRVRAHAQALAQCHGWLSTNAPHLIREAVSSNAEGARLAAQDPTSAAIGGLRSAEEYG
LLAAFHAVQDDPNNRTRFFVLSRKDNASEALGVGCKTSIIVSVPNEVGALFRVVEPFARHGVSMSRFESRPVKSGAWDYN
FYIDIVGSRLEEKVANALAELQQQGAKVKLLGSYFDTDQH

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=273, Percent_Identity=32.967032967033, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30134; Mature: 30134

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAAANLIACLGPVGTYSEDAAILYFGSSSKRLLLPSLDAIFEACESGLASHSVVAVEN
CCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHCCCCCCEEEEEEC
STEGAVPRTLDLLYKTELQICGELSLLLRHDLLTQSGQLHGVTRVRAHAQALAQCHGWLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
TNAPHLIREAVSSNAEGARLAAQDPTSAAIGGLRSAEEYGLLAAFHAVQDDPNNRTRFFV
CCCHHHHHHHHHCCCCCCEEECCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEE
LSRKDNASEALGVGCKTSIIVSVPNEVGALFRVVEPFARHGVSMSRFESRPVKSGAWDYN
EECCCCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEE
FYIDIVGSRLEEKVANALAELQQQGAKVKLLGSYFDTDQH
EEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MRIAAANLIACLGPVGTYSEDAAILYFGSSSKRLLLPSLDAIFEACESGLASHSVVAVEN
CCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHCCCCCCEEEEEEC
STEGAVPRTLDLLYKTELQICGELSLLLRHDLLTQSGQLHGVTRVRAHAQALAQCHGWLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
TNAPHLIREAVSSNAEGARLAAQDPTSAAIGGLRSAEEYGLLAAFHAVQDDPNNRTRFFV
CCCHHHHHHHHHCCCCCCEEECCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEE
LSRKDNASEALGVGCKTSIIVSVPNEVGALFRVVEPFARHGVSMSRFESRPVKSGAWDYN
EECCCCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEE
FYIDIVGSRLEEKVANALAELQQQGAKVKLLGSYFDTDQH
EEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]