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The map label for this gene is htpG [H]

Identifier: 91786520

GI number: 91786520

Start: 621985

End: 623865

Strand: Direct

Name: htpG [H]

Synonym: Bpro_0614

Alternate gene names: 91786520

Gene position: 621985-623865 (Clockwise)

Preceding gene: 91786513

Following gene: 91786521

Centisome position: 11.96

GC content: 61.56

Gene sequence:

>1881_bases
ATGCACAAACAAACCTTGTCCTTTCAAGCCGAAGTTGCCCAGCTCCTGAACCTGGTCACGCATTCGCTGTATTCGAACCC
AGACATCTTCCTGCGTGAACTGATCTCCAATGCCTCCGACGCCTGCGACAAGCTGCGTTTTGAGGCGCTCAATGACGCCG
CACTGTATGAGGGTGACTCCGAGCTCCAGGTGCGCCTGCGCTACAACAAGACGGCCAATACCCTGACCATTACCGACAAC
GGCATCGGCCTGTCCGAAAGGGAGGCGATCGAGAACCTCGGCACGATTGCCAAGAGCGGCACGCGGGATTTCATGGCCAA
GCTGTCCGGCGACCAGAAAAACGATGCGCAGCTGATCGGGCAGTTCGGCGTGGGCTTTTATTCGGGCTTCATCGTGGCCG
ACCGGATCACCGTGGAAAGCCGCCGTGCCGGCCTGCCGGCGACTCAAGGCGTGCGCTGGAGCAGCGAGGGCACCGGCGAG
TTCGAGGTGAGCGAGATGGAGCGCGCCGAACGGGGCACCAGCATCATCCTGCACCTCAAGGACGACGCCCGCGACTACCT
GAACGCCTGGAAGCTCAAGGGCATCATCAACAAATACTCCGACCACATCTCGCTGCCCATCCTGATGCAGAAAGAAGAGT
GGAAAGAAGGCGAAAACGGCCAGCCCGGCGAAATGGTCGTCACGGGTGAATGGGAAACCGTCAACCAGGCCGCCGCGCTC
TGGACCCGTGCCAAGAAAGACATCACGCCCGAGCAGTACGACGAGTTTTACAAGCAGATCAGCTACGACAGCCAGGCGCC
GCTGGCCACCACCCATAACCGGGTGGAGGGCGGGACCGAATACACCCAGCTGCTGTTCATTCCGGCCAAGGCGCCCATGG
ACCTGTTCAATCGCGACAAGGCCGCGGGCGTGAAGCTGTATGTACGCCGTGTTTTCATCATGGACGACGCGCAGGCGCTC
ATGCCGACCTACCTGCGTTTTGTGAAGGGCGTGGTGGATTCCGCGGATCTGCCCCTGAATGTGTCACGCGAGCTGTTGCA
GGAAAGCCGCGCCGTCAAGGCGATTCGCGAAGGCAACACCCGGCGCGTGCTGTCGATGATTGAAGACCTGGCCGCCAATG
ACGCCGACAAGTTCAAGGCGTTTTATGCCGAGTTTGGCGCCGTCCTCAAGGAGGGCCTGGGCGAGGATTTTGCCAACCGC
GAGCGCCTGGCCAAGCTGCTGCGCTTTGCCAGCTCGACGACCGACACCGTCAGCGTGGGCTTTGCCGACTACAAGGCCCG
CATGAAGGAGGGGCAGGACGCGATTTACTACGTCACGGCCGACACCCTGGCTGCCGCAAAGAGCAGCCCGCAACTCGAGA
TCTTTCGCAAGAAGGGCATTGAGGTCCTGCTGATGGCCGACCGCGTGGACGAGTGGGCGCTGAACTACCTGCACGAATTC
GACGGCACGCCGCTGCAGTCGGTGGCCAAGGGAGCGGTAGACCTGGGCAAGCTGCAGGATGAAGACGAGAAGAAAGCCGC
CGAAGAAGCGCAAACCCACTTCAAGCCCATCCTCGACAAGCTCAAGGAAGCCCTAAAAGACAAGGCCAAGGACGTGCGTG
CCACCACGCGCCTGGTGGATTCGCCCGCCTGCCTGGTCGTGCAGGATGGCGACATGTCGACCCAGCTGGCCCGCATGCTG
AAGCAGGCCGGCCAGGCTGTGCCGGAGGTCAAGCCGATCCTGGAGGTCAACGCACAGCATCCGCTGGTGAAAAAGCTGGA
GGCCGGTGAGCACTTTGACGATCTGGCCCACATCCTGTTCGACCAGGCCTTGCTGGCCGAGGGCGGCATGCCGGAAGATC
CGGCTGCGTATGTGAAGCGGGTCAACGCGCTGCTGGTTTGA

Upstream 100 bases:

>100_bases
CAGGCCGGCGCCAGGAGTTGTAAATAATCCCCAACCCCGTGCGCATCACCCAGATTCTGCCATTCAACATGTAACAAGCT
AATTACATTTAATCCTGACC

Downstream 100 bases:

>100_bases
CCTTGGTTTAAGGCTCGCCCAGGGCTGGTTTAATTGCCGGATGCTTACTGGTGAATGGTGAATGGTGAATGGTGAATGGT
GAACTTAAATCAAAAATAGA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MHKQTLSFQAEVAQLLNLVTHSLYSNPDIFLRELISNASDACDKLRFEALNDAALYEGDSELQVRLRYNKTANTLTITDN
GIGLSEREAIENLGTIAKSGTRDFMAKLSGDQKNDAQLIGQFGVGFYSGFIVADRITVESRRAGLPATQGVRWSSEGTGE
FEVSEMERAERGTSIILHLKDDARDYLNAWKLKGIINKYSDHISLPILMQKEEWKEGENGQPGEMVVTGEWETVNQAAAL
WTRAKKDITPEQYDEFYKQISYDSQAPLATTHNRVEGGTEYTQLLFIPAKAPMDLFNRDKAAGVKLYVRRVFIMDDAQAL
MPTYLRFVKGVVDSADLPLNVSRELLQESRAVKAIREGNTRRVLSMIEDLAANDADKFKAFYAEFGAVLKEGLGEDFANR
ERLAKLLRFASSTTDTVSVGFADYKARMKEGQDAIYYVTADTLAAAKSSPQLEIFRKKGIEVLLMADRVDEWALNYLHEF
DGTPLQSVAKGAVDLGKLQDEDEKKAAEEAQTHFKPILDKLKEALKDKAKDVRATTRLVDSPACLVVQDGDMSTQLARML
KQAGQAVPEVKPILEVNAQHPLVKKLEAGEHFDDLAHILFDQALLAEGGMPEDPAAYVKRVNALLV

Sequences:

>Translated_626_residues
MHKQTLSFQAEVAQLLNLVTHSLYSNPDIFLRELISNASDACDKLRFEALNDAALYEGDSELQVRLRYNKTANTLTITDN
GIGLSEREAIENLGTIAKSGTRDFMAKLSGDQKNDAQLIGQFGVGFYSGFIVADRITVESRRAGLPATQGVRWSSEGTGE
FEVSEMERAERGTSIILHLKDDARDYLNAWKLKGIINKYSDHISLPILMQKEEWKEGENGQPGEMVVTGEWETVNQAAAL
WTRAKKDITPEQYDEFYKQISYDSQAPLATTHNRVEGGTEYTQLLFIPAKAPMDLFNRDKAAGVKLYVRRVFIMDDAQAL
MPTYLRFVKGVVDSADLPLNVSRELLQESRAVKAIREGNTRRVLSMIEDLAANDADKFKAFYAEFGAVLKEGLGEDFANR
ERLAKLLRFASSTTDTVSVGFADYKARMKEGQDAIYYVTADTLAAAKSSPQLEIFRKKGIEVLLMADRVDEWALNYLHEF
DGTPLQSVAKGAVDLGKLQDEDEKKAAEEAQTHFKPILDKLKEALKDKAKDVRATTRLVDSPACLVVQDGDMSTQLARML
KQAGQAVPEVKPILEVNAQHPLVKKLEAGEHFDDLAHILFDQALLAEGGMPEDPAAYVKRVNALLV
>Mature_626_residues
MHKQTLSFQAEVAQLLNLVTHSLYSNPDIFLRELISNASDACDKLRFEALNDAALYEGDSELQVRLRYNKTANTLTITDN
GIGLSEREAIENLGTIAKSGTRDFMAKLSGDQKNDAQLIGQFGVGFYSGFIVADRITVESRRAGLPATQGVRWSSEGTGE
FEVSEMERAERGTSIILHLKDDARDYLNAWKLKGIINKYSDHISLPILMQKEEWKEGENGQPGEMVVTGEWETVNQAAAL
WTRAKKDITPEQYDEFYKQISYDSQAPLATTHNRVEGGTEYTQLLFIPAKAPMDLFNRDKAAGVKLYVRRVFIMDDAQAL
MPTYLRFVKGVVDSADLPLNVSRELLQESRAVKAIREGNTRRVLSMIEDLAANDADKFKAFYAEFGAVLKEGLGEDFANR
ERLAKLLRFASSTTDTVSVGFADYKARMKEGQDAIYYVTADTLAAAKSSPQLEIFRKKGIEVLLMADRVDEWALNYLHEF
DGTPLQSVAKGAVDLGKLQDEDEKKAAEEAQTHFKPILDKLKEALKDKAKDVRATTRLVDSPACLVVQDGDMSTQLARML
KQAGQAVPEVKPILEVNAQHPLVKKLEAGEHFDDLAHILFDQALLAEGGMPEDPAAYVKRVNALLV

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=679, Percent_Identity=38.7334315169367, Blast_Score=431, Evalue=1e-121,
Organism=Homo sapiens, GI20149594, Length=681, Percent_Identity=38.1791483113069, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI155722983, Length=637, Percent_Identity=35.6357927786499, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI154146191, Length=408, Percent_Identity=37.5, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI153792590, Length=408, Percent_Identity=37.5, Blast_Score=271, Evalue=1e-72,
Organism=Escherichia coli, GI1786679, Length=629, Percent_Identity=55.1669316375199, Blast_Score=711, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=668, Percent_Identity=39.2215568862275, Blast_Score=444, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17542208, Length=666, Percent_Identity=37.5375375375375, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI115535205, Length=646, Percent_Identity=34.6749226006192, Blast_Score=328, Evalue=6e-90,
Organism=Caenorhabditis elegans, GI115535167, Length=419, Percent_Identity=37.2315035799523, Blast_Score=259, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=38.2352941176471, Blast_Score=436, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6325016, Length=684, Percent_Identity=37.5730994152047, Blast_Score=431, Evalue=1e-121,
Organism=Drosophila melanogaster, GI17647529, Length=682, Percent_Identity=38.8563049853372, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI21357739, Length=676, Percent_Identity=37.1301775147929, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24586016, Length=649, Percent_Identity=36.055469953775, Blast_Score=377, Evalue=1e-105,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 69700; Mature: 69700

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKQTLSFQAEVAQLLNLVTHSLYSNPDIFLRELISNASDACDKLRFEALNDAALYEGDS
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
ELQVRLRYNKTANTLTITDNGIGLSEREAIENLGTIAKSGTRDFMAKLSGDQKNDAQLIG
CEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHH
QFGVGFYSGFIVADRITVESRRAGLPATQGVRWSSEGTGEFEVSEMERAERGTSIILHLK
HHHHHHHHCEEEEEEEEEHHHHCCCCCCCCCEECCCCCCCEEHHHHHHHHCCCEEEEEEC
DDARDYLNAWKLKGIINKYSDHISLPILMQKEEWKEGENGQPGEMVVTGEWETVNQAAAL
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHCCCCCCCCCCEEEECCCHHHHHHHHH
WTRAKKDITPEQYDEFYKQISYDSQAPLATTHNRVEGGTEYTQLLFIPAKAPMDLFNRDK
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHCCCH
AAGVKLYVRRVFIMDDAQALMPTYLRFVKGVVDSADLPLNVSRELLQESRAVKAIREGNT
HCCHHEEHHHHHEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCH
RRVLSMIEDLAANDADKFKAFYAEFGAVLKEGLGEDFANRERLAKLLRFASSTTDTVSVG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEC
FADYKARMKEGQDAIYYVTADTLAAAKSSPQLEIFRKKGIEVLLMADRVDEWALNYLHEF
HHHHHHHHHCCCCEEEEEEHHHHHHHCCCCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHC
DGTPLQSVAKGAVDLGKLQDEDEKKAAEEAQTHFKPILDKLKEALKDKAKDVRATTRLVD
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SPACLVVQDGDMSTQLARMLKQAGQAVPEVKPILEVNAQHPLVKKLEAGEHFDDLAHILF
CCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHCCCCHHHHHHHHH
DQALLAEGGMPEDPAAYVKRVNALLV
HHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MHKQTLSFQAEVAQLLNLVTHSLYSNPDIFLRELISNASDACDKLRFEALNDAALYEGDS
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
ELQVRLRYNKTANTLTITDNGIGLSEREAIENLGTIAKSGTRDFMAKLSGDQKNDAQLIG
CEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHH
QFGVGFYSGFIVADRITVESRRAGLPATQGVRWSSEGTGEFEVSEMERAERGTSIILHLK
HHHHHHHHCEEEEEEEEEHHHHCCCCCCCCCEECCCCCCCEEHHHHHHHHCCCEEEEEEC
DDARDYLNAWKLKGIINKYSDHISLPILMQKEEWKEGENGQPGEMVVTGEWETVNQAAAL
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHCCCCCCCCCCEEEECCCHHHHHHHHH
WTRAKKDITPEQYDEFYKQISYDSQAPLATTHNRVEGGTEYTQLLFIPAKAPMDLFNRDK
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHCCCH
AAGVKLYVRRVFIMDDAQALMPTYLRFVKGVVDSADLPLNVSRELLQESRAVKAIREGNT
HCCHHEEHHHHHEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCH
RRVLSMIEDLAANDADKFKAFYAEFGAVLKEGLGEDFANRERLAKLLRFASSTTDTVSVG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEC
FADYKARMKEGQDAIYYVTADTLAAAKSSPQLEIFRKKGIEVLLMADRVDEWALNYLHEF
HHHHHHHHHCCCCEEEEEEHHHHHHHCCCCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHC
DGTPLQSVAKGAVDLGKLQDEDEKKAAEEAQTHFKPILDKLKEALKDKAKDVRATTRLVD
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SPACLVVQDGDMSTQLARMLKQAGQAVPEVKPILEVNAQHPLVKKLEAGEHFDDLAHILF
CCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHCCCCHHHHHHHHH
DQALLAEGGMPEDPAAYVKRVNALLV
HHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA