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The map label for this gene is echA12 [H]

Identifier: 91786497

GI number: 91786497

Start: 595354

End: 596208

Strand: Reverse

Name: echA12 [H]

Synonym: Bpro_0591

Alternate gene names: 91786497

Gene position: 596208-595354 (Counterclockwise)

Preceding gene: 91786498

Following gene: 91786496

Centisome position: 11.46

GC content: 66.08

Gene sequence:

>855_bases
ATGAAACACTACATAGTCCCCGCCAACCCCATGCACGCGCAGTTCGATGCGCTGGCCACTTACCACGCCCGGCACTTTGC
CTACGCCTTCGACGCCGGCGTGGCCACGCTGACGCTGAACCGCCCCGAGCGCAAAAATCCGCTGACGTTTGACTCCTACG
CCGAACTGCGCGACCTGTTCCGCGCGCTGAACTACGCCACCGACGTGAAGGCGGTGGTGCTCACCGGCGCAGGCGGCAAT
TTCTGCTCGGGTGGCGATGTGCACGAGATCATTGGCCCGCTGACCAAAATGAGCATGCCCGAACTGCTGGAGTTCACGCG
CATGACCGGCGACCTGATCAAGGCGATGCGGCTGTGCCCTCAGCCCGTCATCGCGGCCATCGATGGCATCTGCGCCGGGG
CCGGCGCCATGATGGCGCTGGCGGCCGACATGCGGCTGGGCACCGCGCAGGCCAAGACCGCCTTCCTGTTCACCCGCGTC
GGCCTGGCGGGCGCAGACATGGGCGCCTGCGCGCTGCTGCCGCGCCTGATCGGCCAGGGCCGCGCCTCCGAACTGCTGTT
CACCGGCCGCGCCATGAACGCCCAGGAAGGCCTGCAGTGGGGCTTTTTCAATGCCCTGCATGAGCCCGGTGAGGTGCTGG
CCCAGGCCCACAAGCTGGCCCATGAACTGGCCAGCGGCCCGACCTTTGCACACGGCATGACCAAGACCATGCTGCACCAG
GAATGGGCCATGACGCTGGACCAGGCGATAGAAGCCGAAGCCCAGGCACAGGCCATCTGCATGCAGACCGGCGACTTCAC
GCGCGCCTACGAAGCCTTTGCCGCCAAACAAAAACCGGTGTTCCAGGGCGACTGA

Upstream 100 bases:

>100_bases
TTGAAAGCCTGTCGCCGCGTGAAGTCGAATCGCTCCACAAGCTGCTGGGAAAGGTCAAGCACCACCATATGCAGCAGAAC
GAAACCAAACTGGAAACCGC

Downstream 100 bases:

>100_bases
GCGCCGGGCACAGTCCACAGTCATAAGGAGGTTTTCAGCATGAACCCGACGACAGCACATCTGGCACTGCCGTTTTTTGA
CGGCGTGCACCGTGATCTCG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKHYIVPANPMHAQFDALATYHARHFAYAFDAGVATLTLNRPERKNPLTFDSYAELRDLFRALNYATDVKAVVLTGAGGN
FCSGGDVHEIIGPLTKMSMPELLEFTRMTGDLIKAMRLCPQPVIAAIDGICAGAGAMMALAADMRLGTAQAKTAFLFTRV
GLAGADMGACALLPRLIGQGRASELLFTGRAMNAQEGLQWGFFNALHEPGEVLAQAHKLAHELASGPTFAHGMTKTMLHQ
EWAMTLDQAIEAEAQAQAICMQTGDFTRAYEAFAAKQKPVFQGD

Sequences:

>Translated_284_residues
MKHYIVPANPMHAQFDALATYHARHFAYAFDAGVATLTLNRPERKNPLTFDSYAELRDLFRALNYATDVKAVVLTGAGGN
FCSGGDVHEIIGPLTKMSMPELLEFTRMTGDLIKAMRLCPQPVIAAIDGICAGAGAMMALAADMRLGTAQAKTAFLFTRV
GLAGADMGACALLPRLIGQGRASELLFTGRAMNAQEGLQWGFFNALHEPGEVLAQAHKLAHELASGPTFAHGMTKTMLHQ
EWAMTLDQAIEAEAQAQAICMQTGDFTRAYEAFAAKQKPVFQGD
>Mature_284_residues
MKHYIVPANPMHAQFDALATYHARHFAYAFDAGVATLTLNRPERKNPLTFDSYAELRDLFRALNYATDVKAVVLTGAGGN
FCSGGDVHEIIGPLTKMSMPELLEFTRMTGDLIKAMRLCPQPVIAAIDGICAGAGAMMALAADMRLGTAQAKTAFLFTRV
GLAGADMGACALLPRLIGQGRASELLFTGRAMNAQEGLQWGFFNALHEPGEVLAQAHKLAHELASGPTFAHGMTKTMLHQ
EWAMTLDQAIEAEAQAQAICMQTGDFTRAYEAFAAKQKPVFQGD

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=245, Percent_Identity=29.7959183673469, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI4502327, Length=269, Percent_Identity=28.2527881040892, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI31542718, Length=249, Percent_Identity=23.6947791164659, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI20127408, Length=190, Percent_Identity=25.2631578947368, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI68989263, Length=187, Percent_Identity=28.8770053475936, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI116235487, Length=255, Percent_Identity=25.8823529411765, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI221136756, Length=203, Percent_Identity=26.1083743842365, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI221136753, Length=203, Percent_Identity=26.1083743842365, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI221307494, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787660, Length=257, Percent_Identity=32.6848249027237, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI221142681, Length=269, Percent_Identity=25.6505576208178, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788597, Length=218, Percent_Identity=27.0642201834862, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787659, Length=251, Percent_Identity=27.4900398406374, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=30.2083333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790281, Length=199, Percent_Identity=24.1206030150754, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=248, Percent_Identity=29.8387096774194, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540714, Length=230, Percent_Identity=29.5652173913043, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17534483, Length=274, Percent_Identity=25.9124087591241, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=219, Percent_Identity=26.027397260274, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17554946, Length=254, Percent_Identity=27.1653543307087, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=25.5060728744939, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24653139, Length=259, Percent_Identity=32.046332046332, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19920382, Length=289, Percent_Identity=27.681660899654, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21357171, Length=225, Percent_Identity=30.2222222222222, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24654903, Length=243, Percent_Identity=25.1028806584362, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24650670, Length=206, Percent_Identity=29.126213592233, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20129971, Length=252, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24653477, Length=252, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19922422, Length=252, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 30624; Mature: 30624

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHYIVPANPMHAQFDALATYHARHFAYAFDAGVATLTLNRPERKNPLTFDSYAELRDLF
CCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHH
RALNYATDVKAVVLTGAGGNFCSGGDVHEIIGPLTKMSMPELLEFTRMTGDLIKAMRLCP
HHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
QPVIAAIDGICAGAGAMMALAADMRLGTAQAKTAFLFTRVGLAGADMGACALLPRLIGQG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
RASELLFTGRAMNAQEGLQWGFFNALHEPGEVLAQAHKLAHELASGPTFAHGMTKTMLHQ
CCHHEEEECCCCCHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EWAMTLDQAIEAEAQAQAICMQTGDFTRAYEAFAAKQKPVFQGD
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKHYIVPANPMHAQFDALATYHARHFAYAFDAGVATLTLNRPERKNPLTFDSYAELRDLF
CCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHH
RALNYATDVKAVVLTGAGGNFCSGGDVHEIIGPLTKMSMPELLEFTRMTGDLIKAMRLCP
HHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
QPVIAAIDGICAGAGAMMALAADMRLGTAQAKTAFLFTRVGLAGADMGACALLPRLIGQG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
RASELLFTGRAMNAQEGLQWGFFNALHEPGEVLAQAHKLAHELASGPTFAHGMTKTMLHQ
CCHHEEEECCCCCHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EWAMTLDQAIEAEAQAQAICMQTGDFTRAYEAFAAKQKPVFQGD
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]