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The map label for this gene is siaT [H]

Identifier: 91786464

GI number: 91786464

Start: 556809

End: 558101

Strand: Direct

Name: siaT [H]

Synonym: Bpro_0558

Alternate gene names: 91786464

Gene position: 556809-558101 (Clockwise)

Preceding gene: 91786463

Following gene: 91786465

Centisome position: 10.71

GC content: 64.11

Gene sequence:

>1293_bases
ATGAGCATCGGACTGTTTGGAATTGCATTCGTCGTGATGCTTGGCATGATGCTGGTCGGCATTCCGATCGCCGTCTCGAT
GGCGGCGGTGGGGATCGTGGGGGGCATCGCCGCTTACGGCATCCCCTTCATGGACTCGATCGCGCCCGTGGTCTGGGGTG
TGCACAACGAGAACCTGCTGACCTCGATCCCGCTGTTCATCCTGCTGGGCGAGTTGCTGCTGCGCTCGGGCATTGCCGAT
CGCATGTACATTGCCCTGTCGGCCTGGCTCGGGCGCCTGCCGGGCGGCCTGCTGCATACCAACATCGGCAGTTGCGCGCT
GTTCGCCGCGACCTCCGGTTCGTCGGTGGCCACGGCGGCTACCGTGGGTACCGTTGCGCTGCCGTCCCTGCAAAAACGCG
GCTACCCCATGCGCGCCTCGCTGGGCACGCTGGCAGCGGGCGGCACCCTGGGCATCCTGATCCCGCCCAGCGTGAACATG
ATCGTCTACGGCTCGCTGACCAACAACTCGATCGGCAAGCTCTTCATCGCCGGCATCATTCCCGGTCTGATGCTGACGGG
CTGCTTCATGCTCTACATCGCCGTGTCGTCGCTGATGAGCGGTAACGCCATGCGTGAGCCCAAGGTGCCGATGGCCGACA
AGCTGCGCTCGCTGGTGCATCTGGTGCCGCCCATGGTCGTGTTCGGCATCGTGATGGGCAGCCTGTACTTCGGCATTGCC
ACCACCACCGAAAGCGCGGCGCTGGGCGTGATCGCGGCCCTGGGCTTTGTGGTGCACTCGGGCAAGATGAGCCGCGAACT
GCTGCGCACCTGCTTCATCTCCACGGCGCGCGTCAGCGGCATGATCCTGCTGATCATCACCGCAGCCTTCATCCTCAACC
TGACCATCAGCCTGACCGGCGTCGCCGAGGCGATGACCAAGTGGGTGGCGGGCCTGGGCCTGTCGGCAACTGGGCTGATC
CTGGCGCTGATCGTGTTCTACCTGATTCTCGGCATGTTCATGGATGTGCTGTCGATGCAGGTGGCGACCATCCCGATCAC
CTACCCGATCGCTACGGCGCTGGGCGTGGACCCGATCTGGTTCGGTATCTTCATCGTGCTGATGTGCGAGCTGGGGCTGA
TCACGCCACCGGTGGGCATGAACCTGTTCGTGGTGCACGGCATCCGGCCCGACAAGGGCGGCATCGAGGACGCGATCTGG
GGGGCGCTGCCCTACGCCCTGATCATGATCCTGTTCACCTTGCTCATCATGGTGTGGCCGCAGATTGTCACCTGGCTGCC
GGCCCACATGTGA

Upstream 100 bases:

>100_bases
CGCTGAACCATGACTTCCATCCGAAGAGCGCCAAGGAAGAGCTGAAGGAAGAGCTCGATGACCTGGCCCAGCGCCAGTCC
ACAGAACAGGGAGCACAGCC

Downstream 100 bases:

>100_bases
GGACTGAACACGAATGATAGACAAGGACTTGTGGCGCCTGGGCGCCGTTGAGCTGGGTCAGCGCTTTCGCGAGCGCTCCC
TCACGCCGCTGGCGGTGGCC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSIGLFGIAFVVMLGMMLVGIPIAVSMAAVGIVGGIAAYGIPFMDSIAPVVWGVHNENLLTSIPLFILLGELLLRSGIAD
RMYIALSAWLGRLPGGLLHTNIGSCALFAATSGSSVATAATVGTVALPSLQKRGYPMRASLGTLAAGGTLGILIPPSVNM
IVYGSLTNNSIGKLFIAGIIPGLMLTGCFMLYIAVSSLMSGNAMREPKVPMADKLRSLVHLVPPMVVFGIVMGSLYFGIA
TTTESAALGVIAALGFVVHSGKMSRELLRTCFISTARVSGMILLIITAAFILNLTISLTGVAEAMTKWVAGLGLSATGLI
LALIVFYLILGMFMDVLSMQVATIPITYPIATALGVDPIWFGIFIVLMCELGLITPPVGMNLFVVHGIRPDKGGIEDAIW
GALPYALIMILFTLLIMVWPQIVTWLPAHM

Sequences:

>Translated_430_residues
MSIGLFGIAFVVMLGMMLVGIPIAVSMAAVGIVGGIAAYGIPFMDSIAPVVWGVHNENLLTSIPLFILLGELLLRSGIAD
RMYIALSAWLGRLPGGLLHTNIGSCALFAATSGSSVATAATVGTVALPSLQKRGYPMRASLGTLAAGGTLGILIPPSVNM
IVYGSLTNNSIGKLFIAGIIPGLMLTGCFMLYIAVSSLMSGNAMREPKVPMADKLRSLVHLVPPMVVFGIVMGSLYFGIA
TTTESAALGVIAALGFVVHSGKMSRELLRTCFISTARVSGMILLIITAAFILNLTISLTGVAEAMTKWVAGLGLSATGLI
LALIVFYLILGMFMDVLSMQVATIPITYPIATALGVDPIWFGIFIVLMCELGLITPPVGMNLFVVHGIRPDKGGIEDAIW
GALPYALIMILFTLLIMVWPQIVTWLPAHM
>Mature_429_residues
SIGLFGIAFVVMLGMMLVGIPIAVSMAAVGIVGGIAAYGIPFMDSIAPVVWGVHNENLLTSIPLFILLGELLLRSGIADR
MYIALSAWLGRLPGGLLHTNIGSCALFAATSGSSVATAATVGTVALPSLQKRGYPMRASLGTLAAGGTLGILIPPSVNMI
VYGSLTNNSIGKLFIAGIIPGLMLTGCFMLYIAVSSLMSGNAMREPKVPMADKLRSLVHLVPPMVVFGIVMGSLYFGIAT
TTESAALGVIAALGFVVHSGKMSRELLRTCFISTARVSGMILLIITAAFILNLTISLTGVAEAMTKWVAGLGLSATGLIL
ALIVFYLILGMFMDVLSMQVATIPITYPIATALGVDPIWFGIFIVLMCELGLITPPVGMNLFVVHGIRPDKGGIEDAIWG
ALPYALIMILFTLLIMVWPQIVTWLPAHM

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=349, Percent_Identity=30.945558739255, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45139; Mature: 45007

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIGLFGIAFVVMLGMMLVGIPIAVSMAAVGIVGGIAAYGIPFMDSIAPVVWGVHNENLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHH
TSIPLFILLGELLLRSGIADRMYIALSAWLGRLPGGLLHTNIGSCALFAATSGSSVATAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCCHHHHH
TVGTVALPSLQKRGYPMRASLGTLAAGGTLGILIPPSVNMIVYGSLTNNSIGKLFIAGII
HHHHHHCCHHHHCCCCCCCCHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHH
PGLMLTGCFMLYIAVSSLMSGNAMREPKVPMADKLRSLVHLVPPMVVFGIVMGSLYFGIA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTTESAALGVIAALGFVVHSGKMSRELLRTCFISTARVSGMILLIITAAFILNLTISLTG
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAEAMTKWVAGLGLSATGLILALIVFYLILGMFMDVLSMQVATIPITYPIATALGVDPIW
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCCHHH
FGIFIVLMCELGLITPPVGMNLFVVHGIRPDKGGIEDAIWGALPYALIMILFTLLIMVWP
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QIVTWLPAHM
HHHHHHCCCC
>Mature Secondary Structure 
SIGLFGIAFVVMLGMMLVGIPIAVSMAAVGIVGGIAAYGIPFMDSIAPVVWGVHNENLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHH
TSIPLFILLGELLLRSGIADRMYIALSAWLGRLPGGLLHTNIGSCALFAATSGSSVATAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCCHHHHH
TVGTVALPSLQKRGYPMRASLGTLAAGGTLGILIPPSVNMIVYGSLTNNSIGKLFIAGII
HHHHHHCCHHHHCCCCCCCCHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHH
PGLMLTGCFMLYIAVSSLMSGNAMREPKVPMADKLRSLVHLVPPMVVFGIVMGSLYFGIA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTTESAALGVIAALGFVVHSGKMSRELLRTCFISTARVSGMILLIITAAFILNLTISLTG
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAEAMTKWVAGLGLSATGLILALIVFYLILGMFMDVLSMQVATIPITYPIATALGVDPIW
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCCHHH
FGIFIVLMCELGLITPPVGMNLFVVHGIRPDKGGIEDAIWGALPYALIMILFTLLIMVWP
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QIVTWLPAHM
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]