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The map label for this gene is yafC [H]

Identifier: 91786426

GI number: 91786426

Start: 522746

End: 523669

Strand: Direct

Name: yafC [H]

Synonym: Bpro_0517

Alternate gene names: 91786426

Gene position: 522746-523669 (Clockwise)

Preceding gene: 91786421

Following gene: 91786427

Centisome position: 10.05

GC content: 56.28

Gene sequence:

>924_bases
ATGGACAAGCTGTCTGCAATGAAGACTTTTGTGCGTGTGGTCGAAGCTGGCAGCTTCTCGGCGGTGGCAGACGAGATGCG
CGCGACTCAAAGCGCTATCAGCAAGCAGGTTGCGGCTTTGGAAAAAGAGTTGGGGACCAAGTTGCTGATCAGAACGACGC
GGTCGCTTTCCTTGTCGGAAGAGGGCGAGCGCTATTTCGAGCAGGCACGTAGGCTTGTTGGCGAGATCGCCGAGGCCGAG
TCGGATTTGCGCAAAGGGGAAGGCCGGCTAAGTGGTTGGTTGCGAGTGGCCGCCTCGGTAGGCTTTGGTCGTCTCAAACT
CATGCCTTTGGTGAAGGCATTCATGGATACTCACGCCGGTGTGAAAATCGACCTGCGGCTGCATGATGGTTTTATCGACC
TGATTGAGCAGGGAATCGACATCTCGGTGCGCATAGGCGAACTGCCTGACAGTGGGCTGATCGCTCGTCGCGTAGGCACC
TCGCAACGAATGCTCTTGGCGCATCGCGATTACTTAAGAAGCTTGCCCAAAGGCGTCAAGGCACCAGTGAATCCAGAGGA
CTTGTCCAATCACAACTGCGTTGTATATACCGAGCTAGCCACCCGTAATCTATGGGCCTTTGAAGCCGGGGCCGGAGCTT
CTGAACCGCTCGGAACTGTCAAGGCGGTTCGGGTGGGGGGCCGCATACAAACGAACAGTAGCGAAGTGATCCGCTCTGCT
GTGACAGCTGGGATGGGTATTGGCTATTCGCCAACTTGGCTTTTCGAGTCCGAGTTGGCACGTGGTGAGGTGGTCCGTGT
CATGCCTGACTGGCAGTCGCCTCATTTGCCGATTCATATGGTGAGCCCGCCTGAGCGTAAACATTCGGCGAAGGTCAAGG
CGTTCGTCGAGCACGTTGCATTGGAGCTGACGAGTGGAAAATAG

Upstream 100 bases:

>100_bases
TTGGGTTGCTAGGAGCCTCAACTGTGACTGATTCCAAAGAGTTGATATAGACTGGTTTTGGTTGTATCAATTAGTAGATA
ATGGAATATATGGAGGTGTC

Downstream 100 bases:

>100_bases
GCGTAAGCGTCATCCCAGCACCGTTCTTGCCTGCTGAGGGATGCACTGAGAGCATGGCCTGCATGACAACACCTGCAGGC
ACTCCCTCCGAATCCGCCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDKLSAMKTFVRVVEAGSFSAVADEMRATQSAISKQVAALEKELGTKLLIRTTRSLSLSEEGERYFEQARRLVGEIAEAE
SDLRKGEGRLSGWLRVAASVGFGRLKLMPLVKAFMDTHAGVKIDLRLHDGFIDLIEQGIDISVRIGELPDSGLIARRVGT
SQRMLLAHRDYLRSLPKGVKAPVNPEDLSNHNCVVYTELATRNLWAFEAGAGASEPLGTVKAVRVGGRIQTNSSEVIRSA
VTAGMGIGYSPTWLFESELARGEVVRVMPDWQSPHLPIHMVSPPERKHSAKVKAFVEHVALELTSGK

Sequences:

>Translated_307_residues
MDKLSAMKTFVRVVEAGSFSAVADEMRATQSAISKQVAALEKELGTKLLIRTTRSLSLSEEGERYFEQARRLVGEIAEAE
SDLRKGEGRLSGWLRVAASVGFGRLKLMPLVKAFMDTHAGVKIDLRLHDGFIDLIEQGIDISVRIGELPDSGLIARRVGT
SQRMLLAHRDYLRSLPKGVKAPVNPEDLSNHNCVVYTELATRNLWAFEAGAGASEPLGTVKAVRVGGRIQTNSSEVIRSA
VTAGMGIGYSPTWLFESELARGEVVRVMPDWQSPHLPIHMVSPPERKHSAKVKAFVEHVALELTSGK
>Mature_307_residues
MDKLSAMKTFVRVVEAGSFSAVADEMRATQSAISKQVAALEKELGTKLLIRTTRSLSLSEEGERYFEQARRLVGEIAEAE
SDLRKGEGRLSGWLRVAASVGFGRLKLMPLVKAFMDTHAGVKIDLRLHDGFIDLIEQGIDISVRIGELPDSGLIARRVGT
SQRMLLAHRDYLRSLPKGVKAPVNPEDLSNHNCVVYTELATRNLWAFEAGAGASEPLGTVKAVRVGGRIQTNSSEVIRSA
VTAGMGIGYSPTWLFESELARGEVVRVMPDWQSPHLPIHMVSPPERKHSAKVKAFVEHVALELTSGK

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=35.2542372881356, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=32, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1789639, Length=300, Percent_Identity=32, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789440, Length=297, Percent_Identity=30.976430976431, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI87081978, Length=275, Percent_Identity=30.5454545454545, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787128, Length=299, Percent_Identity=28.4280936454849, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=28.5223367697594, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789173, Length=297, Percent_Identity=25.5892255892256, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790262, Length=277, Percent_Identity=27.7978339350181, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788706, Length=299, Percent_Identity=22.4080267558528, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=27.2108843537415, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=25.296442687747, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33595; Mature: 33595

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLSAMKTFVRVVEAGSFSAVADEMRATQSAISKQVAALEKELGTKLLIRTTRSLSLSE
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCH
EGERYFEQARRLVGEIAEAESDLRKGEGRLSGWLRVAASVGFGRLKLMPLVKAFMDTHAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
VKIDLRLHDGFIDLIEQGIDISVRIGELPDSGLIARRVGTSQRMLLAHRDYLRSLPKGVK
EEEEEEECCCHHHHHHCCCCEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHCHHCCC
APVNPEDLSNHNCVVYTELATRNLWAFEAGAGASEPLGTVKAVRVGGRIQTNSSEVIRSA
CCCCHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCCHHHHEEECCEEECCHHHHHHHH
VTAGMGIGYSPTWLFESELARGEVVRVMPDWQSPHLPIHMVSPPERKHSAKVKAFVEHVA
HHHCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHHHHH
LELTSGK
HHCCCCC
>Mature Secondary Structure
MDKLSAMKTFVRVVEAGSFSAVADEMRATQSAISKQVAALEKELGTKLLIRTTRSLSLSE
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCH
EGERYFEQARRLVGEIAEAESDLRKGEGRLSGWLRVAASVGFGRLKLMPLVKAFMDTHAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
VKIDLRLHDGFIDLIEQGIDISVRIGELPDSGLIARRVGTSQRMLLAHRDYLRSLPKGVK
EEEEEEECCCHHHHHHCCCCEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHCHHCCC
APVNPEDLSNHNCVVYTELATRNLWAFEAGAGASEPLGTVKAVRVGGRIQTNSSEVIRSA
CCCCHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCCHHHHEEECCEEECCHHHHHHHH
VTAGMGIGYSPTWLFESELARGEVVRVMPDWQSPHLPIHMVSPPERKHSAKVKAFVEHVA
HHHCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHHHHH
LELTSGK
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]