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The map label for this gene is gntR [H]

Identifier: 91786346

GI number: 91786346

Start: 453172

End: 454203

Strand: Direct

Name: gntR [H]

Synonym: Bpro_0436

Alternate gene names: 91786346

Gene position: 453172-454203 (Clockwise)

Preceding gene: 91786340

Following gene: 91786349

Centisome position: 8.71

GC content: 66.86

Gene sequence:

>1032_bases
ATGCCTGCCCCTGCCCTGACTCACTCTCCTGGCTTTAAAGCCGCCACCCTTCATGATGTCGCCCGGGAAGCCGGCGTCTC
GCTGATCACCGCATCGCGAGCGCTGAGCAACCCGACGCTGGTGTCCGACAAGACGATCGAACGTGTGCAGAAGGCCGTCG
AGGCCACGGGCTACATTCCCAACCTGCTGGCTGGCGGACTCAAGTCCAGGCGCAGCCTGATGGTGGCCGGGCTCGTGCCC
ACGATCTCGGTCGCCCAATTCCTGCCCACCGTGCAGTCGCTGACCGAGGCGCTGGACGCCGACGGCTACCAGCTCATCCT
GGGGCAGACCGGTTACAACCGTTCCCGCGAGGACGCCTTGCTCAACACCATGATCAGCCGCCGGCCGGATGGCATCGTGG
TGACGGGTCTGGTGCATTCGCAGGCTGCCAGGGAAAGGCTGCGCCGCCTGGGCATCCCCATCGTCGAGACCTGGGACCTG
AGCGATCGCCCCATTGACATGCTGGTGGGTTTTTCCCACCTGAAGGTTGGCAGCGCAGTCGCGGGCTACTTTCTGGGCAA
GGGCTGGCATCGGCTCGGGATCGCCACTGGCGATGACCATCGCGGCTCGTTGCGGCGCGAGGGTTTTCTGGCAACCGTCG
GCCATGAGGTGCCGACCGCAGTGGTGCCCGCCCCGAGCAACCTGGCGCTGGGACGGCGGGCGCTGGCCGAACTGCTGCAG
CAGGACCCAAAACTCGAGGCCGTCTACTGCAGCTCGGACCAGCTGGCGCAAGGCGTGCTGGTCGAGGCGCAGGCACGGGG
CCTGCGGGTCCCCGAGGACCTGGCGGTCTGCGGTTTTGGCGATGCAGACTTCGCGGCCCACCTGCAGCCCTCGCTGACCA
CGGTGCATGTCGACGGTGCCGCCATCGGCAGACTGGCTGCGCGGCTCATCGTTGCACGCTGCCGGGGGGAACCCATTGCA
GAACGCGTCATCGATGTGGGCTTTCGCATTGTCGAGAGGCAGTCAACCGGGGGCGGTGCCAGCCAGGCTTGA

Upstream 100 bases:

>100_bases
CAGCCCACTGCGTTGTCACGCCTTGCCTGGCACGCCGATCACGGCGCACTCGGACGCATCCAACTGCCGTTTCCAGGTTT
AATCGGACAATCGCCTGGCC

Downstream 100 bases:

>100_bases
TGTTTTCTTCGGGTTGACGCCTCAGCTCAGTACAGGGAGGGCAAGCTGTGGTACGGATCAGGTCAGGCTCTTGCGCAGCC
AGTCCGCGAAGGCCGCACAT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MPAPALTHSPGFKAATLHDVAREAGVSLITASRALSNPTLVSDKTIERVQKAVEATGYIPNLLAGGLKSRRSLMVAGLVP
TISVAQFLPTVQSLTEALDADGYQLILGQTGYNRSREDALLNTMISRRPDGIVVTGLVHSQAARERLRRLGIPIVETWDL
SDRPIDMLVGFSHLKVGSAVAGYFLGKGWHRLGIATGDDHRGSLRREGFLATVGHEVPTAVVPAPSNLALGRRALAELLQ
QDPKLEAVYCSSDQLAQGVLVEAQARGLRVPEDLAVCGFGDADFAAHLQPSLTTVHVDGAAIGRLAARLIVARCRGEPIA
ERVIDVGFRIVERQSTGGGASQA

Sequences:

>Translated_343_residues
MPAPALTHSPGFKAATLHDVAREAGVSLITASRALSNPTLVSDKTIERVQKAVEATGYIPNLLAGGLKSRRSLMVAGLVP
TISVAQFLPTVQSLTEALDADGYQLILGQTGYNRSREDALLNTMISRRPDGIVVTGLVHSQAARERLRRLGIPIVETWDL
SDRPIDMLVGFSHLKVGSAVAGYFLGKGWHRLGIATGDDHRGSLRREGFLATVGHEVPTAVVPAPSNLALGRRALAELLQ
QDPKLEAVYCSSDQLAQGVLVEAQARGLRVPEDLAVCGFGDADFAAHLQPSLTTVHVDGAAIGRLAARLIVARCRGEPIA
ERVIDVGFRIVERQSTGGGASQA
>Mature_342_residues
PAPALTHSPGFKAATLHDVAREAGVSLITASRALSNPTLVSDKTIERVQKAVEATGYIPNLLAGGLKSRRSLMVAGLVPT
ISVAQFLPTVQSLTEALDADGYQLILGQTGYNRSREDALLNTMISRRPDGIVVTGLVHSQAARERLRRLGIPIVETWDLS
DRPIDMLVGFSHLKVGSAVAGYFLGKGWHRLGIATGDDHRGSLRREGFLATVGHEVPTAVVPAPSNLALGRRALAELLQQ
DPKLEAVYCSSDQLAQGVLVEAQARGLRVPEDLAVCGFGDADFAAHLQPSLTTVHVDGAAIGRLAARLIVARCRGEPIAE
RVIDVGFRIVERQSTGGGASQA

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=28.75, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1790715, Length=320, Percent_Identity=29.0625, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1787948, Length=339, Percent_Identity=27.7286135693215, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790369, Length=331, Percent_Identity=28.3987915407855, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=28.1818181818182, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788474, Length=313, Percent_Identity=28.1150159744409, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786540, Length=334, Percent_Identity=23.9520958083832, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787906, Length=258, Percent_Identity=27.1317829457364, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36388; Mature: 36257

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPALTHSPGFKAATLHDVAREAGVSLITASRALSNPTLVSDKTIERVQKAVEATGYIP
CCCCCCCCCCCCCHHHHHHHHHHHCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHCCCCH
NLLAGGLKSRRSLMVAGLVPTISVAQFLPTVQSLTEALDADGYQLILGQTGYNRSREDAL
HHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHH
LNTMISRRPDGIVVTGLVHSQAARERLRRLGIPIVETWDLSDRPIDMLVGFSHLKVGSAV
HHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHCHHHHHHHHHH
AGYFLGKGWHRLGIATGDDHRGSLRREGFLATVGHEVPTAVVPAPSNLALGRRALAELLQ
HHHHHCCCHHEEECCCCCCCCCCHHHCCCEEECCCCCCCEEECCCCCHHHHHHHHHHHHH
QDPKLEAVYCSSDQLAQGVLVEAQARGLRVPEDLAVCGFGDADFAAHLQPSLTTVHVDGA
CCCCCEEEEECCHHHHHCCEEEHHHCCCCCCHHHEEECCCCCCHHHHCCCCEEEEEECHH
AIGRLAARLIVARCRGEPIAERVIDVGFRIVERQSTGGGASQA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCCCC
>Mature Secondary Structure 
PAPALTHSPGFKAATLHDVAREAGVSLITASRALSNPTLVSDKTIERVQKAVEATGYIP
CCCCCCCCCCCCHHHHHHHHHHHCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHCCCCH
NLLAGGLKSRRSLMVAGLVPTISVAQFLPTVQSLTEALDADGYQLILGQTGYNRSREDAL
HHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHH
LNTMISRRPDGIVVTGLVHSQAARERLRRLGIPIVETWDLSDRPIDMLVGFSHLKVGSAV
HHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHCHHHHHHHHHH
AGYFLGKGWHRLGIATGDDHRGSLRREGFLATVGHEVPTAVVPAPSNLALGRRALAELLQ
HHHHHCCCHHEEECCCCCCCCCCHHHCCCEEECCCCCCCEEECCCCCHHHHHHHHHHHHH
QDPKLEAVYCSSDQLAQGVLVEAQARGLRVPEDLAVCGFGDADFAAHLQPSLTTVHVDGA
CCCCCEEEEECCHHHHHCCEEEHHHCCCCCCHHHEEECCCCCCHHHHCCCCEEEEEECHH
AIGRLAARLIVARCRGEPIAERVIDVGFRIVERQSTGGGASQA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]