Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 91786334

GI number: 91786334

Start: 438233

End: 439078

Strand: Reverse

Name: appC [H]

Synonym: Bpro_0424

Alternate gene names: 91786334

Gene position: 439078-438233 (Counterclockwise)

Preceding gene: 91786335

Following gene: 91786333

Centisome position: 8.44

GC content: 66.31

Gene sequence:

>846_bases
ATGATGAAAAGTCCTTTTTGGCAACGCTTCTGCCGCAACAAGGGTGCCGTGATCGGCATGGCCGTGCTGCTGCTGGTGGC
CGTCGTTGCGCTCATCGGCCCGTCGATCGCATCGAACGACCCGTGGGGCATGGTGCAGCAGCCCTTCCTCCGCCCGTGGA
CCGAACCCGGCTTTGCGATGGGCACCGACACGCTGGGCCGCGACATCATGTCGGGCGTCATCTACGGCGCGCGCATCTCG
CTGCTGATCGGCGTGGTGTCTACCGTCGTCGCGCTGCTGATCGGCGTCACGCTGGGCGCCATCGCCGGCTACTTCGGCGG
CTGGATCGATGCAGCGCTGATGCGCTTCACCGAAATCTTCCAGGCCGTGCCCAGCTTTGCGCTGGCCATCGTGCTGGTCG
CGATCTTCCAGCCCTCGGTCGGCTCCATCGTGGCGGCCATTGCCATCGTGTCCTGGCCGCCGGTGGCGCGCCTGGTGCGC
AGCGAGTTCCTCACACTGCGCCAGCGCGACTTCGTGCAGGCGGCGCTGCTGGCCGGCCAGTCGACGCCGCGCATCATCCT
CACGCAAATCCTGCCCAACGCCATGTCGCCCATCATCGTGATGGCTTCGTTGATGGTGGCCACGGCCATCCTGCTGGAGT
CGAGCCTGAGCTTCCTGGGTCTCGGCGACCCGAACCAGATGAGCTGGGGCTACATGGTCGGCTCGGCCCGCACGGTGCTG
CGCCAGGCCTGGTGGATGGCGCTGTTCCCGGGGCTGGCCATCGTGCTGACGGTGCTTGCGCTCAATCTCGTGGGCGAAGG
GCTGAACGACGGCCTCAACACACGACTCGACGGGAGGAGCAAATGA

Upstream 100 bases:

>100_bases
TGCTGCTTGGCGCCTTCCTGGTCACCGCGGCCATGGCGGTGCTGTTCAACCTGATCACCGACCTCGTCTACACGCTGGTC
GATCCGAGAATCGAATTGAC

Downstream 100 bases:

>100_bases
ACGCCACCGTGACGCCGATGAAGCCGGTGCAACCCGTGCTCGACATCGTCGACCTGAGCATCTGCCTGCCCAAGGGTGCC
GACCGCGCGCTGGCCGTCGA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MMKSPFWQRFCRNKGAVIGMAVLLLVAVVALIGPSIASNDPWGMVQQPFLRPWTEPGFAMGTDTLGRDIMSGVIYGARIS
LLIGVVSTVVALLIGVTLGAIAGYFGGWIDAALMRFTEIFQAVPSFALAIVLVAIFQPSVGSIVAAIAIVSWPPVARLVR
SEFLTLRQRDFVQAALLAGQSTPRIILTQILPNAMSPIIVMASLMVATAILLESSLSFLGLGDPNQMSWGYMVGSARTVL
RQAWWMALFPGLAIVLTVLALNLVGEGLNDGLNTRLDGRSK

Sequences:

>Translated_281_residues
MMKSPFWQRFCRNKGAVIGMAVLLLVAVVALIGPSIASNDPWGMVQQPFLRPWTEPGFAMGTDTLGRDIMSGVIYGARIS
LLIGVVSTVVALLIGVTLGAIAGYFGGWIDAALMRFTEIFQAVPSFALAIVLVAIFQPSVGSIVAAIAIVSWPPVARLVR
SEFLTLRQRDFVQAALLAGQSTPRIILTQILPNAMSPIIVMASLMVATAILLESSLSFLGLGDPNQMSWGYMVGSARTVL
RQAWWMALFPGLAIVLTVLALNLVGEGLNDGLNTRLDGRSK
>Mature_281_residues
MMKSPFWQRFCRNKGAVIGMAVLLLVAVVALIGPSIASNDPWGMVQQPFLRPWTEPGFAMGTDTLGRDIMSGVIYGARIS
LLIGVVSTVVALLIGVTLGAIAGYFGGWIDAALMRFTEIFQAVPSFALAIVLVAIFQPSVGSIVAAIAIVSWPPVARLVR
SEFLTLRQRDFVQAALLAGQSTPRIILTQILPNAMSPIIVMASLMVATAILLESSLSFLGLGDPNQMSWGYMVGSARTVL
RQAWWMALFPGLAIVLTVLALNLVGEGLNDGLNTRLDGRSK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=282, Percent_Identity=40.0709219858156, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1789964, Length=277, Percent_Identity=44.4043321299639, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787498, Length=273, Percent_Identity=36.6300366300366, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1787760, Length=261, Percent_Identity=37.1647509578544, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789889, Length=218, Percent_Identity=34.4036697247706, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788505, Length=230, Percent_Identity=32.1739130434783, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787549, Length=273, Percent_Identity=31.5018315018315, Blast_Score=114, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30057; Mature: 30057

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKSPFWQRFCRNKGAVIGMAVLLLVAVVALIGPSIASNDPWGMVQQPFLRPWTEPGFAM
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCC
GTDTLGRDIMSGVIYGARISLLIGVVSTVVALLIGVTLGAIAGYFGGWIDAALMRFTEIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVPSFALAIVLVAIFQPSVGSIVAAIAIVSWPPVARLVRSEFLTLRQRDFVQAALLAGQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
STPRIILTQILPNAMSPIIVMASLMVATAILLESSLSFLGLGDPNQMSWGYMVGSARTVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RQAWWMALFPGLAIVLTVLALNLVGEGLNDGLNTRLDGRSK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMKSPFWQRFCRNKGAVIGMAVLLLVAVVALIGPSIASNDPWGMVQQPFLRPWTEPGFAM
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCC
GTDTLGRDIMSGVIYGARISLLIGVVSTVVALLIGVTLGAIAGYFGGWIDAALMRFTEIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVPSFALAIVLVAIFQPSVGSIVAAIAIVSWPPVARLVRSEFLTLRQRDFVQAALLAGQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
STPRIILTQILPNAMSPIIVMASLMVATAILLESSLSFLGLGDPNQMSWGYMVGSARTVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RQAWWMALFPGLAIVLTVLALNLVGEGLNDGLNTRLDGRSK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]