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The map label for this gene is dgdA [H]

Identifier: 91786324

GI number: 91786324

Start: 426739

End: 427989

Strand: Reverse

Name: dgdA [H]

Synonym: Bpro_0414

Alternate gene names: 91786324

Gene position: 427989-426739 (Counterclockwise)

Preceding gene: 91786325

Following gene: 91786323

Centisome position: 8.23

GC content: 70.66

Gene sequence:

>1251_bases
ATGGACCGCCGCGCGCGGCTGCTGGGCCCGGCCTATCGCCTGTTCTACGAAACGCCGCTGCACCCGGTGCGCGGCGAAGG
CGTCTGGCTCTACGACGCCGACGGCACGCGCTACCTCGACGCCTACAACAACGTCGCGTCGGTGGGCCACTGCCACCCGC
ACGTGGTCGAGGCCATCGCCCGCCAGGCGAGCGTGCTCAACACGCACACCCGCTACCTGCACGAGGGCGTGCTCGACTAC
GCCGAGCGGCTGCTCGGCACGATGCCTTCCGGGCTCGCCCATGCGATGTTCACCTGCACCGGCAGCGAAGCCAACGACCT
GGCAATGCGCATCGCCCGATCGCACACCAAGGCCGAAGGGCTGATCGTCACGCGCTTCGCCTACCACGGCGTGACCGCGG
CCATCGCCGAAGCGTCGCCCTCGCTCGGCAAGTTCGTGCAGCTCGGCGAGGCGGTGCGCACCGAGCCGGCGCCCGACAGT
TACCGCATCGCACCCGAAGCCATGGGCGCGACCTTCGCCGCCGGCGTGCGCGAGGCCATTGCCGATCTGCGGGCCCATGG
CATGCGGCCCGCCGCGCTGATGGTCGACACCGTCTTTTCCAGCGACGGCATCTTCACCGACCCGCCCGGCTTCCTGGCCG
AAGCGGTGGACGCGATCCGCGAAGCCGGCGGCGTGTTCATCGCCGACGAGGTGCAGCCCGGGCTGGGCCGCACGGGCGAT
GCCTTCTGGGGCTTCCTGCGCCACGGCGTGCTGCCCGACATCGTGACCATGGGCAAGCCCCTCGGCGCCGGCCATCCGCT
GGCCGGTTTGGCGATTCGCCCCGACGTGCTGGCGGCGTTCGGCCGCGAGTGCCGCTACTTCAACACCTTCGGCGGCAACC
CGGTGTCGATGGCGGCCGGCATGGCCGTGCTGGACGTGATCGAGCAGGAGGGCCTGATGGACAACGCCCAGCGGGTGGGC
CGCTACCTGCGGATACGGCTGAGCGAACTGGGCCGGCGCCATGCGCTCATCGGCGATGTGCGCGGCGCGGGCCTGTTCGT
CGGCGTGGAGATGGTGACCGACCGCGGCACACGGGCGCCCGCCACTGCGCAGACGGCGCGCATCGTCAATGCGCTGCGCG
AGCGGGGCGTGCTGCTCAGCGGCACGGGCGAACACGCCAACACGCTGAAGATCCGTCCGCCGCTGGTGTTCTCCGAAGCC
AACGCGGACATGCTGGTCGAGACGCTGGACAGCGTTCTGACAACCCTGTAA

Upstream 100 bases:

>100_bases
CACAACGCCGCGACGGACGCCCTGCGGCGCGCCTGCGGCCTGGACTGAGATCACCGACATGCCGCCCATTTCCCACACCA
CCCACACCACCCGGGACCTC

Downstream 100 bases:

>100_bases
ACAGGATTCCCATGTCTGACATCTGGCGTCTCTCCGCATCCCGGGTCGCGAACCTGATCGCCCAGCGCAAGCTGTCTGCC
ACCGAAGCGGCCGAATCGGC

Product: aminotransferase

Products: NA

Alternate protein names: DGD [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDRRARLLGPAYRLFYETPLHPVRGEGVWLYDADGTRYLDAYNNVASVGHCHPHVVEAIARQASVLNTHTRYLHEGVLDY
AERLLGTMPSGLAHAMFTCTGSEANDLAMRIARSHTKAEGLIVTRFAYHGVTAAIAEASPSLGKFVQLGEAVRTEPAPDS
YRIAPEAMGATFAAGVREAIADLRAHGMRPAALMVDTVFSSDGIFTDPPGFLAEAVDAIREAGGVFIADEVQPGLGRTGD
AFWGFLRHGVLPDIVTMGKPLGAGHPLAGLAIRPDVLAAFGRECRYFNTFGGNPVSMAAGMAVLDVIEQEGLMDNAQRVG
RYLRIRLSELGRRHALIGDVRGAGLFVGVEMVTDRGTRAPATAQTARIVNALRERGVLLSGTGEHANTLKIRPPLVFSEA
NADMLVETLDSVLTTL

Sequences:

>Translated_416_residues
MDRRARLLGPAYRLFYETPLHPVRGEGVWLYDADGTRYLDAYNNVASVGHCHPHVVEAIARQASVLNTHTRYLHEGVLDY
AERLLGTMPSGLAHAMFTCTGSEANDLAMRIARSHTKAEGLIVTRFAYHGVTAAIAEASPSLGKFVQLGEAVRTEPAPDS
YRIAPEAMGATFAAGVREAIADLRAHGMRPAALMVDTVFSSDGIFTDPPGFLAEAVDAIREAGGVFIADEVQPGLGRTGD
AFWGFLRHGVLPDIVTMGKPLGAGHPLAGLAIRPDVLAAFGRECRYFNTFGGNPVSMAAGMAVLDVIEQEGLMDNAQRVG
RYLRIRLSELGRRHALIGDVRGAGLFVGVEMVTDRGTRAPATAQTARIVNALRERGVLLSGTGEHANTLKIRPPLVFSEA
NADMLVETLDSVLTTL
>Mature_416_residues
MDRRARLLGPAYRLFYETPLHPVRGEGVWLYDADGTRYLDAYNNVASVGHCHPHVVEAIARQASVLNTHTRYLHEGVLDY
AERLLGTMPSGLAHAMFTCTGSEANDLAMRIARSHTKAEGLIVTRFAYHGVTAAIAEASPSLGKFVQLGEAVRTEPAPDS
YRIAPEAMGATFAAGVREAIADLRAHGMRPAALMVDTVFSSDGIFTDPPGFLAEAVDAIREAGGVFIADEVQPGLGRTGD
AFWGFLRHGVLPDIVTMGKPLGAGHPLAGLAIRPDVLAAFGRECRYFNTFGGNPVSMAAGMAVLDVIEQEGLMDNAQRVG
RYLRIRLSELGRRHALIGDVRGAGLFVGVEMVTDRGTRAPATAQTARIVNALRERGVLLSGTGEHANTLKIRPPLVFSEA
NADMLVETLDSVLTTL

Specific function: The dialkylglycine decarboxylase is of interest because it normally catalyzes both decarboxylation and amino transfer. It may be more properly described as a decarboxylating aminotransferase rather than an aminotransferring decarboxylase [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=426, Percent_Identity=43.6619718309859, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI24119277, Length=425, Percent_Identity=44, Blast_Score=346, Evalue=2e-95,
Organism=Homo sapiens, GI226442705, Length=426, Percent_Identity=42.2535211267606, Blast_Score=344, Evalue=8e-95,
Organism=Homo sapiens, GI226442709, Length=381, Percent_Identity=44.3569553805774, Blast_Score=328, Evalue=4e-90,
Organism=Homo sapiens, GI13994255, Length=436, Percent_Identity=33.9449541284404, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI4557809, Length=413, Percent_Identity=27.3607748184019, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI188536080, Length=434, Percent_Identity=23.7327188940092, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI38679950, Length=434, Percent_Identity=23.7327188940092, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI38679946, Length=434, Percent_Identity=23.7327188940092, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI284507298, Length=227, Percent_Identity=30.3964757709251, Blast_Score=92, Evalue=7e-19,
Organism=Escherichia coli, GI1789016, Length=409, Percent_Identity=31.7848410757946, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1788044, Length=391, Percent_Identity=27.8772378516624, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI145693181, Length=399, Percent_Identity=27.3182957393484, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=30.6172839506173, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1789759, Length=387, Percent_Identity=25.5813953488372, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786349, Length=324, Percent_Identity=26.5432098765432, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71992977, Length=436, Percent_Identity=38.302752293578, Blast_Score=310, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=34.7222222222222, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI25144271, Length=409, Percent_Identity=28.361858190709, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71992985, Length=130, Percent_Identity=40, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25144274, Length=270, Percent_Identity=28.5185185185185, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=438, Percent_Identity=24.4292237442922, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323470, Length=411, Percent_Identity=26.7639902676399, Blast_Score=122, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6324432, Length=405, Percent_Identity=26.4197530864197, Blast_Score=109, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=455, Percent_Identity=23.956043956044, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356575, Length=428, Percent_Identity=42.0560747663551, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=35.827664399093, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI28574759, Length=442, Percent_Identity=35.972850678733, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI21357415, Length=414, Percent_Identity=27.2946859903382, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281366494, Length=435, Percent_Identity=24.5977011494253, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24667139, Length=435, Percent_Identity=24.5977011494253, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24667143, Length=435, Percent_Identity=24.5977011494253, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =4.1.1.64 [H]

Molecular weight: Translated: 44622; Mature: 44622

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRRARLLGPAYRLFYETPLHPVRGEGVWLYDADGTRYLDAYNNVASVGHCHPHVVEAIA
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEHHHHHCHHHHCCCCHHHHHHHH
RQASVLNTHTRYLHEGVLDYAERLLGTMPSGLAHAMFTCTGSEANDLAMRIARSHTKAEG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCHHHHHHHHHHHHCCCCC
LIVTRFAYHGVTAAIAEASPSLGKFVQLGEAVRTEPAPDSYRIAPEAMGATFAAGVREAI
EEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHH
ADLRAHGMRPAALMVDTVFSSDGIFTDPPGFLAEAVDAIREAGGVFIADEVQPGLGRTGD
HHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHH
AFWGFLRHGVLPDIVTMGKPLGAGHPLAGLAIRPDVLAAFGRECRYFNTFGGNPVSMAAG
HHHHHHHHCCCHHHHHCCCCCCCCCCCCCEEECHHHHHHHCCCCCEEECCCCCHHHHHHH
MAVLDVIEQEGLMDNAQRVGRYLRIRLSELGRRHALIGDVRGAGLFVGVEMVTDRGTRAP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEEEEECCCCCCC
ATAQTARIVNALRERGVLLSGTGEHANTLKIRPPLVFSEANADMLVETLDSVLTTL
CHHHHHHHHHHHHHCCEEEECCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDRRARLLGPAYRLFYETPLHPVRGEGVWLYDADGTRYLDAYNNVASVGHCHPHVVEAIA
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEHHHHHCHHHHCCCCHHHHHHHH
RQASVLNTHTRYLHEGVLDYAERLLGTMPSGLAHAMFTCTGSEANDLAMRIARSHTKAEG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCHHHHHHHHHHHHCCCCC
LIVTRFAYHGVTAAIAEASPSLGKFVQLGEAVRTEPAPDSYRIAPEAMGATFAAGVREAI
EEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHH
ADLRAHGMRPAALMVDTVFSSDGIFTDPPGFLAEAVDAIREAGGVFIADEVQPGLGRTGD
HHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHH
AFWGFLRHGVLPDIVTMGKPLGAGHPLAGLAIRPDVLAAFGRECRYFNTFGGNPVSMAAG
HHHHHHHHCCCHHHHHCCCCCCCCCCCCCEEECHHHHHHHCCCCCEEECCCCCHHHHHHH
MAVLDVIEQEGLMDNAQRVGRYLRIRLSELGRRHALIGDVRGAGLFVGVEMVTDRGTRAP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEEEEECCCCCCC
ATAQTARIVNALRERGVLLSGTGEHANTLKIRPPLVFSEANADMLVETLDSVLTTL
CHHHHHHHHHHHHHCCEEEECCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2180928; 8342040; 7947767; 7799433; 10556038 [H]