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The map label for this gene is tcyB [H]

Identifier: 91786312

GI number: 91786312

Start: 413237

End: 414058

Strand: Direct

Name: tcyB [H]

Synonym: Bpro_0402

Alternate gene names: 91786312

Gene position: 413237-414058 (Clockwise)

Preceding gene: 91786311

Following gene: 91786313

Centisome position: 7.95

GC content: 65.09

Gene sequence:

>822_bases
ATGCCATCGCCCCGCAGATGGCCGGAGAGCCCCATGAAGTTTGCGTTTCCCGAATGGCCCGGGCACTGGAGCCGGCAACA
GCGCAGCAGTGCGACCATGGTGCTGGCCAGCGTGGTGCTGGTGGTCTTGCTGTGGCTGATGGCCATTCCGCTGGCCCTGG
TGCCCGAACCGATTGGCGTGAATGCGCAGTCCTTTGCCAAAGGCACCCGTGTCACGGTGCAGCTCACCGTGATCGCCGGG
CTGGTTGGCATTGTCATCGGTGTGCTGGCGGCCCTGGGCAAGATATCCCGGCTGCCGCCGCTGCGCTGGATCGCTTCGCT
CTACATCTGGGTCGTGCGCGGCACGCCGCTGCTGGTGCAGGTGCTGTTCGTCTTCCTGGCCTTGCCAACGCTGGTGCCGG
CGCTGCAGCTGAGCGATTTCTCCTCGGCCTGTGTGGCGCTGGCCTTCAACGCCGGGGCCTACAACGCCGAGGCCATCCGC
AGCGGCCTTCTTGCGGTACCGAAGGGGCAGATCGAGGCTGCCCGTTCCCTGGGGCTGTCGAGTTTTTTCACCTTCATCGA
CGTGACCTTTCCGCAGGCTTTCAAGATATCGCTGCCGCCGCTGGTCAACAACACGGTGGCCCTGCTCAAGGACTCGTCGC
TGGCCTATGCGATCGGCGTCGTGGAACTGACCAATGTGGGCAATCGCATCCAGGCCGCCACGTTCCAGCCGCTGCCCACG
CTGGTGACCACGGCGGTCATCTACCTGGTGCTCACGACCGTGCTCACCCAGATTTCGGGCGCGGTGGAGCGCCGCTACGA
CGTGGAAGGACGCCAGCCATGA

Upstream 100 bases:

>100_bases
CAAGGCTACAACAAGGCGCTGGCGGACGTGCTGGCCGATGGCAGCTACAGCGCACTGTCGAAGAGGTACTTCAATGAAGA
CGTACGCTGCAAGTAAGCGC

Downstream 100 bases:

>100_bases
GCCGCCGGGCCGCTCCCAAGGCGAATACTGCAGCGCGCAGCGCGGAGCTTATCCGCCGCCGGACCGCTCCCAAGGCGAAT
GACACTGCAGCGCGCAGCGC

Product: amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MPSPRRWPESPMKFAFPEWPGHWSRQQRSSATMVLASVVLVVLLWLMAIPLALVPEPIGVNAQSFAKGTRVTVQLTVIAG
LVGIVIGVLAALGKISRLPPLRWIASLYIWVVRGTPLLVQVLFVFLALPTLVPALQLSDFSSACVALAFNAGAYNAEAIR
SGLLAVPKGQIEAARSLGLSSFFTFIDVTFPQAFKISLPPLVNNTVALLKDSSLAYAIGVVELTNVGNRIQAATFQPLPT
LVTTAVIYLVLTTVLTQISGAVERRYDVEGRQP

Sequences:

>Translated_273_residues
MPSPRRWPESPMKFAFPEWPGHWSRQQRSSATMVLASVVLVVLLWLMAIPLALVPEPIGVNAQSFAKGTRVTVQLTVIAG
LVGIVIGVLAALGKISRLPPLRWIASLYIWVVRGTPLLVQVLFVFLALPTLVPALQLSDFSSACVALAFNAGAYNAEAIR
SGLLAVPKGQIEAARSLGLSSFFTFIDVTFPQAFKISLPPLVNNTVALLKDSSLAYAIGVVELTNVGNRIQAATFQPLPT
LVTTAVIYLVLTTVLTQISGAVERRYDVEGRQP
>Mature_272_residues
PSPRRWPESPMKFAFPEWPGHWSRQQRSSATMVLASVVLVVLLWLMAIPLALVPEPIGVNAQSFAKGTRVTVQLTVIAGL
VGIVIGVLAALGKISRLPPLRWIASLYIWVVRGTPLLVQVLFVFLALPTLVPALQLSDFSSACVALAFNAGAYNAEAIRS
GLLAVPKGQIEAARSLGLSSFFTFIDVTFPQAFKISLPPLVNNTVALLKDSSLAYAIGVVELTNVGNRIQAATFQPLPTL
VTTAVIYLVLTTVLTQISGAVERRYDVEGRQP

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=207, Percent_Identity=34.2995169082126, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787030, Length=202, Percent_Identity=38.6138613861386, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1788645, Length=207, Percent_Identity=30.4347826086957, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082239, Length=210, Percent_Identity=35.2380952380952, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788646, Length=211, Percent_Identity=31.2796208530806, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786873, Length=205, Percent_Identity=27.3170731707317, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787086, Length=207, Percent_Identity=30.9178743961353, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787087, Length=232, Percent_Identity=29.3103448275862, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI48994930, Length=169, Percent_Identity=36.094674556213, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786874, Length=219, Percent_Identity=23.2876712328767, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29413; Mature: 29282

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPRRWPESPMKFAFPEWPGHWSRQQRSSATMVLASVVLVVLLWLMAIPLALVPEPIGV
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NAQSFAKGTRVTVQLTVIAGLVGIVIGVLAALGKISRLPPLRWIASLYIWVVRGTPLLVQ
CHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHH
VLFVFLALPTLVPALQLSDFSSACVALAFNAGAYNAEAIRSGLLAVPKGQIEAARSLGLS
HHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHHH
SFFTFIDVTFPQAFKISLPPLVNNTVALLKDSSLAYAIGVVELTNVGNRIQAATFQPLPT
HHHHHHHHCCCCEEEEECCCHHCCHHHEEECCCCEEHHHHHHHHCCCCEEECCCCCCHHH
LVTTAVIYLVLTTVLTQISGAVERRYDVEGRQP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PSPRRWPESPMKFAFPEWPGHWSRQQRSSATMVLASVVLVVLLWLMAIPLALVPEPIGV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NAQSFAKGTRVTVQLTVIAGLVGIVIGVLAALGKISRLPPLRWIASLYIWVVRGTPLLVQ
CHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHH
VLFVFLALPTLVPALQLSDFSSACVALAFNAGAYNAEAIRSGLLAVPKGQIEAARSLGLS
HHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHHH
SFFTFIDVTFPQAFKISLPPLVNNTVALLKDSSLAYAIGVVELTNVGNRIQAATFQPLPT
HHHHHHHHCCCCEEEEECCCHHCCHHHEEECCCCEEHHHHHHHHCCCCEEECCCCCCHHH
LVTTAVIYLVLTTVLTQISGAVERRYDVEGRQP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]