Click here to switch to the map view.

The map label for this gene is gmhA [H]

Identifier: 91786302

GI number: 91786302

Start: 404810

End: 405409

Strand: Direct

Name: gmhA [H]

Synonym: Bpro_0392

Alternate gene names: 91786302

Gene position: 404810-405409 (Clockwise)

Preceding gene: 91786301

Following gene: 91786303

Centisome position: 7.78

GC content: 62.5

Gene sequence:

>600_bases
ATGCTTGAACAACGTATTGAACAGCACTTTATCGACAGTGCCGACCTGAAATACCAGGCGGCGCATATCCTGTCCAAACC
GATCTCCGCGGCCATCCAGGCCATCCTTGCCAGCGTAACCAGCGGCGGCAAGGTACTGGCTTGCGGCAATGGCGGCTCGG
CGGCCGACGCCCAGCACTTCGCCGCAGAATTCGTGGGCCGCTATGAGCGGGAGCGGCCGGAGCTGGGTGCCATCGCCCTG
ACGACGGACAGTTCCATCATCACGGCGATTGCCAACGATTACGACTTCAACGTCATTTTTTCCAAGCAGGTCCGTGCGCT
CGGCGGCGCTGGCGACGTGTTGCTCGCCATCAGTACCAGCGGCAACTCGGCCAACGTGCTGGCGGCCGTTGAAGCGGCGC
ATGAGCGTGAGATGACCGTGGTGGCACTCACCGGCCGGGGCGGCGGCAAGATGACGCATGCCTTGCGCGAAACCGACGTG
CATATCTGTGTGCCGCATGAGCGAACCGCGCGCATCCAGGAGGTGCATCTTCTCGTGCTCCACTGCATCTGCGACGGCGT
GGACACCCAGCTACTTGGCGACCAGGAGAATCCCGCATGA

Upstream 100 bases:

>100_bases
GCGGCGTATTTTGTAACCAGGATTGTCTTTGCCGGCTCCCCCGGCCGGATCCATGCCCCTCCCGGGTCTGGCCTTCCTCG
TGACCCGCTATCATTGACGC

Downstream 100 bases:

>100_bases
AGTATTCCGTGATGAAGCGACTGGCTTTGTTTGTCTGCGCAACGGCGGCCGTGGCAGGCGGGCTGACGGCCTGCGTGCCG
CTCGCGATGGGCGGCGCGGC

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MLEQRIEQHFIDSADLKYQAAHILSKPISAAIQAILASVTSGGKVLACGNGGSAADAQHFAAEFVGRYERERPELGAIAL
TTDSSIITAIANDYDFNVIFSKQVRALGGAGDVLLAISTSGNSANVLAAVEAAHEREMTVVALTGRGGGKMTHALRETDV
HICVPHERTARIQEVHLLVLHCICDGVDTQLLGDQENPA

Sequences:

>Translated_199_residues
MLEQRIEQHFIDSADLKYQAAHILSKPISAAIQAILASVTSGGKVLACGNGGSAADAQHFAAEFVGRYERERPELGAIAL
TTDSSIITAIANDYDFNVIFSKQVRALGGAGDVLLAISTSGNSANVLAAVEAAHEREMTVVALTGRGGGKMTHALRETDV
HICVPHERTARIQEVHLLVLHCICDGVDTQLLGDQENPA
>Mature_199_residues
MLEQRIEQHFIDSADLKYQAAHILSKPISAAIQAILASVTSGGKVLACGNGGSAADAQHFAAEFVGRYERERPELGAIAL
TTDSSIITAIANDYDFNVIFSKQVRALGGAGDVLLAISTSGNSANVLAAVEAAHEREMTVVALTGRGGGKMTHALRETDV
HICVPHERTARIQEVHLLVLHCICDGVDTQLLGDQENPA

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=196, Percent_Identity=50.5102040816327, Blast_Score=197, Evalue=5e-52,
Organism=Escherichia coli, GI1786416, Length=156, Percent_Identity=51.2820512820513, Blast_Score=150, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21067; Mature: 21067

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQRIEQHFIDSADLKYQAAHILSKPISAAIQAILASVTSGGKVLACGNGGSAADAQHF
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
AAEFVGRYERERPELGAIALTTDSSIITAIANDYDFNVIFSKQVRALGGAGDVLLAISTS
HHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCEEEEEHHHHHHCCCCCCEEEEEECC
GNSANVLAAVEAAHEREMTVVALTGRGGGKMTHALRETDVHICVPHERTARIQEVHLLVL
CCCCEEEEEEHHHCCCCEEEEEEECCCCCHHHHHHHHCCEEEECCCHHHHHHHHHHHHHH
HCICDGVDTQLLGDQENPA
HHHHCCCCCHHCCCCCCCC
>Mature Secondary Structure
MLEQRIEQHFIDSADLKYQAAHILSKPISAAIQAILASVTSGGKVLACGNGGSAADAQHF
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
AAEFVGRYERERPELGAIALTTDSSIITAIANDYDFNVIFSKQVRALGGAGDVLLAISTS
HHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCEEEEEHHHHHHCCCCCCEEEEEECC
GNSANVLAAVEAAHEREMTVVALTGRGGGKMTHALRETDVHICVPHERTARIQEVHLLVL
CCCCEEEEEEHHHCCCCEEEEEEECCCCCHHHHHHHHCCEEEECCCHHHHHHHHHHHHHH
HCICDGVDTQLLGDQENPA
HHHHCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA