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The map label for this gene is atpA1 [H]

Identifier: 91786236

GI number: 91786236

Start: 346624

End: 348177

Strand: Direct

Name: atpA1 [H]

Synonym: Bpro_0325

Alternate gene names: 91786236

Gene position: 346624-348177 (Clockwise)

Preceding gene: 91786235

Following gene: 91786237

Centisome position: 6.67

GC content: 62.23

Gene sequence:

>1554_bases
ATGCAACTCAATCCCGCAGAAATTTCTGAACTGATCAAGAGCCGTATCGAAGGCCTGACTGTCAGTGCCGACATTCGCAA
CCAGGGCACCGTGGTTTCGGTGACCGACGGTATTGTCCGCATCCACGGCCTGTCCGATGTGATGCAGGGCGAGATGCTGG
AATTCCCCGCGACCGCCGACGGCACGCCTACTTACGGCCTGGCGCTGAACCTCGAGCGTGACTCGGTCGGCTCCGTGATT
CTGGGCGAGTACGAGCACATTGCCGAAGGCGACACCGTCAAGTGCACGGGCCGCATTCTGGAAGTACCGGTCGGACCGGA
GCTGCTGGGCCGTGTGGTCAACGCGCTGGGCCAGCCGATCGACGGCAAAGGCCCGATCAATGCCAAGATGACCGACGTGA
TCGAAAAGGTGGCGCCCGGGGTGATCGCCCGTAAATCCGTTGACCAGCCCCTGCAGACCGGCCTGAAGTCCATCGACTCC
ATGGTGCCCGTCGGCCGTGGCCAGCGCGAACTGATCATCGGCGACCGCCAGACCGGCAAGACCGCCGTGGCCATCGACGC
CATCATCAACCAGAAGGGCAAAGGCGTTTCCTGCGTCTATGTCGCGATCGGCCAGAAGGCCTCCTCGATCAAGAACGTGG
TTCGCTCGCTGGAGCAGGCCGGCGCGATGGAGTACACCATTGTGGTGGCGGCTTCCGCTTCCGAGTCGGCCGCCATGCAA
TATGTGAGCGCCTACTCCGGCTGTACGATGGGCGAATACTTCCGCGATCGTGGTGAAGATGCGCTGATTGTGTATGACGA
TCTGTCCAAGCAGGCCGTGGCTTACCGCCAGGTCTCGTTGCTGCTGCGCCGTCCACCCGGCCGCGAAGCCTACCCTGGCG
ACGTGTTCTATCTGCACAGCCGCCTGCTCGAGCGCGCAGCCCGCGTGAACGAGAAGTATGTTGAAGACTTCACCAAAGGC
GCCGTCAAGGGCAAGACCGGCTCGCTGACCGCACTGCCGATCATCGAAACGCAGGCTGGCGACGTGTCCGCTTTCGTGCC
GACCAACGTGATCTCGATCACCGACGGCCAGATCTTCCTGGAAACCAGCCTGTTCAACGCCGGTATCCGTCCCGCGATCA
ACGCCGGTATCTCGGTGTCCCGCGTCGGTGGCGCCGCCCAGACCAAGCTGATCAAGAACCTGTCCGGCGGTATCCGTACC
GACCTGGCCCAGTACCGTGAACTGGCCGCTTTTGCGCAGTTCGCTTCCGACCTGGATGAAGCCACCCGCAAGCAGCTGGA
CCGCGGTGCCCGCGTGACCGAGTTGCTCAAGCAGGCCCAGTACTCGCCCCTGTCCATCTCCAACATGGCCGCCACGCTGT
TCGCTGTGAACAAGGGCTTCATGGATGACGTGGAAGTCAAGAAGGTCCTGGCTTTCGAGCACGGCCTGCATGCCTGGCTC
AAGGACAAGAACGCTGCGCTGATGGCCAAGCTGGAAGCCAACAAGGCCATGGACAAGGACGCCGAGGCCGAGTTGAACAC
GGCAGTGGCTGCGTTCAAGAAGGCGTTTGCCTGA

Upstream 100 bases:

>100_bases
GCCCGTTTAGAGCAAATGAAAGTGGCGCTGATTTCTTGAGCCGGCGCCTTCGCGCATCTCCCAAGTCTTTAGCCAACAAC
CTAGAAAGAAGGAAAGAGTC

Downstream 100 bases:

>100_bases
GCCAGCCTGAACAGTAGCCCTCAAGAAACCATCAGGAACCCTTAGGACCAACTATGGCAGCAGGCAAGGAAATACGCGGC
AAGATCAAATCGGTGGAAAA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1 [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MQLNPAEISELIKSRIEGLTVSADIRNQGTVVSVTDGIVRIHGLSDVMQGEMLEFPATADGTPTYGLALNLERDSVGSVI
LGEYEHIAEGDTVKCTGRILEVPVGPELLGRVVNALGQPIDGKGPINAKMTDVIEKVAPGVIARKSVDQPLQTGLKSIDS
MVPVGRGQRELIIGDRQTGKTAVAIDAIINQKGKGVSCVYVAIGQKASSIKNVVRSLEQAGAMEYTIVVAASASESAAMQ
YVSAYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEKYVEDFTKG
AVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETSLFNAGIRPAINAGISVSRVGGAAQTKLIKNLSGGIRT
DLAQYRELAAFAQFASDLDEATRKQLDRGARVTELLKQAQYSPLSISNMAATLFAVNKGFMDDVEVKKVLAFEHGLHAWL
KDKNAALMAKLEANKAMDKDAEAELNTAVAAFKKAFA

Sequences:

>Translated_517_residues
MQLNPAEISELIKSRIEGLTVSADIRNQGTVVSVTDGIVRIHGLSDVMQGEMLEFPATADGTPTYGLALNLERDSVGSVI
LGEYEHIAEGDTVKCTGRILEVPVGPELLGRVVNALGQPIDGKGPINAKMTDVIEKVAPGVIARKSVDQPLQTGLKSIDS
MVPVGRGQRELIIGDRQTGKTAVAIDAIINQKGKGVSCVYVAIGQKASSIKNVVRSLEQAGAMEYTIVVAASASESAAMQ
YVSAYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEKYVEDFTKG
AVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETSLFNAGIRPAINAGISVSRVGGAAQTKLIKNLSGGIRT
DLAQYRELAAFAQFASDLDEATRKQLDRGARVTELLKQAQYSPLSISNMAATLFAVNKGFMDDVEVKKVLAFEHGLHAWL
KDKNAALMAKLEANKAMDKDAEAELNTAVAAFKKAFA
>Mature_517_residues
MQLNPAEISELIKSRIEGLTVSADIRNQGTVVSVTDGIVRIHGLSDVMQGEMLEFPATADGTPTYGLALNLERDSVGSVI
LGEYEHIAEGDTVKCTGRILEVPVGPELLGRVVNALGQPIDGKGPINAKMTDVIEKVAPGVIARKSVDQPLQTGLKSIDS
MVPVGRGQRELIIGDRQTGKTAVAIDAIINQKGKGVSCVYVAIGQKASSIKNVVRSLEQAGAMEYTIVVAASASESAAMQ
YVSAYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEKYVEDFTKG
AVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETSLFNAGIRPAINAGISVSRVGGAAQTKLIKNLSGGIRT
DLAQYRELAAFAQFASDLDEATRKQLDRGARVTELLKQAQYSPLSISNMAATLFAVNKGFMDDVEVKKVLAFEHGLHAWL
KDKNAALMAKLEANKAMDKDAEAELNTAVAAFKKAFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=519, Percent_Identity=56.4547206165703, Blast_Score=586, Evalue=1e-167,
Organism=Homo sapiens, GI4757810, Length=519, Percent_Identity=56.4547206165703, Blast_Score=586, Evalue=1e-167,
Organism=Homo sapiens, GI19913426, Length=381, Percent_Identity=27.0341207349081, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI32189394, Length=324, Percent_Identity=26.8518518518519, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI19913428, Length=316, Percent_Identity=27.2151898734177, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI19913424, Length=333, Percent_Identity=25.8258258258258, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=69.2007797270955, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=291, Percent_Identity=28.8659793814433, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790170, Length=375, Percent_Identity=25.8666666666667, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71988063, Length=519, Percent_Identity=54.3352601156069, Blast_Score=563, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71988080, Length=519, Percent_Identity=54.3352601156069, Blast_Score=562, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988074, Length=519, Percent_Identity=50.2890173410405, Blast_Score=511, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17510931, Length=378, Percent_Identity=25.6613756613757, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=340, Percent_Identity=27.0588235294118, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=367, Percent_Identity=25.0681198910082, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=267, Percent_Identity=27.7153558052434, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=56, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=521, Percent_Identity=53.3589251439539, Blast_Score=561, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6322581, Length=429, Percent_Identity=26.1072261072261, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6319603, Length=402, Percent_Identity=27.363184079602, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24658560, Length=519, Percent_Identity=56.0693641618497, Blast_Score=574, Evalue=1e-164,
Organism=Drosophila melanogaster, GI281361666, Length=343, Percent_Identity=27.4052478134111, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24646341, Length=343, Percent_Identity=27.4052478134111, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136796, Length=343, Percent_Identity=27.4052478134111, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24638766, Length=386, Percent_Identity=25.1295336787565, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28574560, Length=323, Percent_Identity=26.9349845201238, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24583992, Length=326, Percent_Identity=26.6871165644172, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583988, Length=268, Percent_Identity=27.6119402985075, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583986, Length=268, Percent_Identity=27.6119402985075, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583984, Length=268, Percent_Identity=27.6119402985075, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129479, Length=318, Percent_Identity=26.4150943396226, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55337; Mature: 55337

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNPAEISELIKSRIEGLTVSADIRNQGTVVSVTDGIVRIHGLSDVMQGEMLEFPATAD
CCCCHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCEEEEECHHHHHCCCCEECCCCCC
GTPTYGLALNLERDSVGSVILGEYEHIAEGDTVKCTGRILEVPVGPELLGRVVNALGQPI
CCCCEEEEEEECCCCCCCEEECCHHHHCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCC
DGKGPINAKMTDVIEKVAPGVIARKSVDQPLQTGLKSIDSMVPVGRGQRELIIGDRQTGK
CCCCCCCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
TAVAIDAIINQKGKGVSCVYVAIGQKASSIKNVVRSLEQAGAMEYTIVVAASASESAAMQ
EEEEHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHH
YVSAYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHS
HHHHHCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
RLLERAARVNEKYVEDFTKGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEE
ETSLFNAGIRPAINAGISVSRVGGAAQTKLIKNLSGGIRTDLAQYRELAAFAQFASDLDE
EEEHHCCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ATRKQLDRGARVTELLKQAQYSPLSISNMAATLFAVNKGFMDDVEVKKVLAFEHGLHAWL
HHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
KDKNAALMAKLEANKAMDKDAEAELNTAVAAFKKAFA
CCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLNPAEISELIKSRIEGLTVSADIRNQGTVVSVTDGIVRIHGLSDVMQGEMLEFPATAD
CCCCHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCEEEEECHHHHHCCCCEECCCCCC
GTPTYGLALNLERDSVGSVILGEYEHIAEGDTVKCTGRILEVPVGPELLGRVVNALGQPI
CCCCEEEEEEECCCCCCCEEECCHHHHCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCC
DGKGPINAKMTDVIEKVAPGVIARKSVDQPLQTGLKSIDSMVPVGRGQRELIIGDRQTGK
CCCCCCCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
TAVAIDAIINQKGKGVSCVYVAIGQKASSIKNVVRSLEQAGAMEYTIVVAASASESAAMQ
EEEEHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHH
YVSAYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHS
HHHHHCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
RLLERAARVNEKYVEDFTKGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEE
ETSLFNAGIRPAINAGISVSRVGGAAQTKLIKNLSGGIRTDLAQYRELAAFAQFASDLDE
EEEHHCCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ATRKQLDRGARVTELLKQAQYSPLSISNMAATLFAVNKGFMDDVEVKKVLAFEHGLHAWL
HHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
KDKNAALMAKLEANKAMDKDAEAELNTAVAAFKKAFA
CCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA