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The map label for this gene is dacC [H]

Identifier: 91786161

GI number: 91786161

Start: 272345

End: 273547

Strand: Direct

Name: dacC [H]

Synonym: Bpro_0250

Alternate gene names: 91786161

Gene position: 272345-273547 (Clockwise)

Preceding gene: 91786160

Following gene: 91786162

Centisome position: 5.24

GC content: 65.09

Gene sequence:

>1203_bases
ATGTACTGTTCACTCAAGGTCCCACGCGGCCTGCGCGCCGCCGCCCTGCTGCTGCTTGTTTCCGCTTTCCTTCCCGTCGC
GCACGCACAGGCCCCCCAGGCGCCTGAGATCGCCGCACGTTCGTATTTGCTGCTGGATGTCACGGCCAACCAGATCCTGG
CCGCCAAGGACATTGATTCCCCGGTCGAGCCGGCATCGCTGACCAAGCTGATGACCGAGTACCTGGTGTTTGACGCGCTC
AAGTCCAAAAAAATCGACCTGAAGCAGACCTTTGGCGTGAGCGAGCGGGCCTGGAAGATGCCAGGCTCCCGCATGTTCAT
CGACCCCAAGATGCAGGTGCCGGTGGAAGACCTGATCAAGGGCATGGTGGTCCAGTCGGGCAACGACGCCACCATGGCGC
TTGCCGAGGGTGTGGGCGGGACGGCCGAGCATTTTGTGCGGCTGATGAACGAGCAGGCCAAGGCCCTGGGAATGAAATCC
ACCGCGTACAAGAATCCGGAAGGCCTGACCGAGCCGGGGCATACCACCACCGCGCGCGACCTGAGCATCCTGGCGACCCG
CCTGATGCGTGATTTCCCCGACTACATCGGCTATTCGGCGATCAAGAAGTATCGCTATCCCGGCACGCCTGCGGCCAATG
ACACCAACCGCAACACCCTGCTGTTCCGCGACCCGACCGTGGACGGTCTGAAAACCGGGCACACAGAGGCGGCGGGTTAC
TGCATGATCGCCACGGCCAGGCGCGACTTCCCGAATCTGGGTGTCGGCGGTGCCCCCGGCGGCCGTCGCCTGCTGGCCAT
TGTGCTGGGCACCAGCAGCGACAGCGCCCGCGCCAACGAGTCGCAAAAACTGCTGAACTGGGGCTACACCGCCTTTGAAG
CCGTGAAGCTGTTCGATGCGGGCCAGCCGGTGGTGGCGCCTTCTGTCTGGAAAGGCGCGGCCTCGACGGTGAAGCTGGGC
CGGCCCGAGGCCATTGTGGTCGCCGTGGCGGCCGGCAGTGCCCCCAAGGTCAAAACCCAGGTCGCCCGGCCGGACCCCCT
GGTGGCGCCCTTTGTGAAGGGCCAGCAGCTGGGAACCCTCAAGGTCATGCTGGGTGAGAATCCCACGCCGGTGGCCGAGG
TGCAGCTGGTGGCGCTGGAGGCGGTGGAAGAGGCCGGCATTCTCGGGCGCGCCTGGGACTCCATCCGGCTCTGGATCAAG
TAA

Upstream 100 bases:

>100_bases
CCCCGATCTGAGCTTGCCGGATCCCTCGCGGTTGCCCGCCTCCCGTTCTGCTGGCTCCTTCTTCCTCTCCTTTTCCTTTT
CCCCTAACGAATTTCCCGAC

Downstream 100 bases:

>100_bases
CTCGCGGCATCAAATGCGGTGGATCCTTTGCGCCGCAAGGTAAATATCTCAGAATTTAAGGTGCTTTAGCGGAAGTGTGT
GCTAACGTTCATATATTGAG

Product: penicillin-binding protein 6

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MYCSLKVPRGLRAAALLLLVSAFLPVAHAQAPQAPEIAARSYLLLDVTANQILAAKDIDSPVEPASLTKLMTEYLVFDAL
KSKKIDLKQTFGVSERAWKMPGSRMFIDPKMQVPVEDLIKGMVVQSGNDATMALAEGVGGTAEHFVRLMNEQAKALGMKS
TAYKNPEGLTEPGHTTTARDLSILATRLMRDFPDYIGYSAIKKYRYPGTPAANDTNRNTLLFRDPTVDGLKTGHTEAAGY
CMIATARRDFPNLGVGGAPGGRRLLAIVLGTSSDSARANESQKLLNWGYTAFEAVKLFDAGQPVVAPSVWKGAASTVKLG
RPEAIVVAVAAGSAPKVKTQVARPDPLVAPFVKGQQLGTLKVMLGENPTPVAEVQLVALEAVEEAGILGRAWDSIRLWIK

Sequences:

>Translated_400_residues
MYCSLKVPRGLRAAALLLLVSAFLPVAHAQAPQAPEIAARSYLLLDVTANQILAAKDIDSPVEPASLTKLMTEYLVFDAL
KSKKIDLKQTFGVSERAWKMPGSRMFIDPKMQVPVEDLIKGMVVQSGNDATMALAEGVGGTAEHFVRLMNEQAKALGMKS
TAYKNPEGLTEPGHTTTARDLSILATRLMRDFPDYIGYSAIKKYRYPGTPAANDTNRNTLLFRDPTVDGLKTGHTEAAGY
CMIATARRDFPNLGVGGAPGGRRLLAIVLGTSSDSARANESQKLLNWGYTAFEAVKLFDAGQPVVAPSVWKGAASTVKLG
RPEAIVVAVAAGSAPKVKTQVARPDPLVAPFVKGQQLGTLKVMLGENPTPVAEVQLVALEAVEEAGILGRAWDSIRLWIK
>Mature_400_residues
MYCSLKVPRGLRAAALLLLVSAFLPVAHAQAPQAPEIAARSYLLLDVTANQILAAKDIDSPVEPASLTKLMTEYLVFDAL
KSKKIDLKQTFGVSERAWKMPGSRMFIDPKMQVPVEDLIKGMVVQSGNDATMALAEGVGGTAEHFVRLMNEQAKALGMKS
TAYKNPEGLTEPGHTTTARDLSILATRLMRDFPDYIGYSAIKKYRYPGTPAANDTNRNTLLFRDPTVDGLKTGHTEAAGY
CMIATARRDFPNLGVGGAPGGRRLLAIVLGTSSDSARANESQKLLNWGYTAFEAVKLFDAGQPVVAPSVWKGAASTVKLG
RPEAIVVAVAAGSAPKVKTQVARPDPLVAPFVKGQQLGTLKVMLGENPTPVAEVQLVALEAVEEAGILGRAWDSIRLWIK

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=404, Percent_Identity=38.1188118811881, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI1786851, Length=401, Percent_Identity=33.6658354114713, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI87082022, Length=395, Percent_Identity=34.1772151898734, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI87082054, Length=220, Percent_Identity=30.9090909090909, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42867; Mature: 42867

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYCSLKVPRGLRAAALLLLVSAFLPVAHAQAPQAPEIAARSYLLLDVTANQILAAKDIDS
CEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEEEEECCCCEEEECCCCC
PVEPASLTKLMTEYLVFDALKSKKIDLKQTFGVSERAWKMPGSRMFIDPKMQVPVEDLIK
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHCCCCCEEEECCCCCCCHHHHHH
GMVVQSGNDATMALAEGVGGTAEHFVRLMNEQAKALGMKSTAYKNPEGLTEPGHTTTARD
HHEEECCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCHHH
LSILATRLMRDFPDYIGYSAIKKYRYPGTPAANDTNRNTLLFRDPTVDGLKTGHTEAAGY
HHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCE
CMIATARRDFPNLGVGGAPGGRRLLAIVLGTSSDSARANESQKLLNWGYTAFEAVKLFDA
EEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHHCC
GQPVVAPSVWKGAASTVKLGRPEAIVVAVAAGSAPKVKTQVARPDPLVAPFVKGQQLGTL
CCCCCCCHHHCCCCCEEECCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCEE
KVMLGENPTPVAEVQLVALEAVEEAGILGRAWDSIRLWIK
EEEECCCCCCHHHEEHHHHHHHHHCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MYCSLKVPRGLRAAALLLLVSAFLPVAHAQAPQAPEIAARSYLLLDVTANQILAAKDIDS
CEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEEEEECCCCEEEECCCCC
PVEPASLTKLMTEYLVFDALKSKKIDLKQTFGVSERAWKMPGSRMFIDPKMQVPVEDLIK
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHCCCCCEEEECCCCCCCHHHHHH
GMVVQSGNDATMALAEGVGGTAEHFVRLMNEQAKALGMKSTAYKNPEGLTEPGHTTTARD
HHEEECCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCHHH
LSILATRLMRDFPDYIGYSAIKKYRYPGTPAANDTNRNTLLFRDPTVDGLKTGHTEAAGY
HHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCE
CMIATARRDFPNLGVGGAPGGRRLLAIVLGTSSDSARANESQKLLNWGYTAFEAVKLFDA
EEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHHCC
GQPVVAPSVWKGAASTVKLGRPEAIVVAVAAGSAPKVKTQVARPDPLVAPFVKGQQLGTL
CCCCCCCHHHCCCCCEEECCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCEE
KVMLGENPTPVAEVQLVALEAVEEAGILGRAWDSIRLWIK
EEEECCCCCCHHHEEHHHHHHHHHCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]