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The map label for this gene is recQ [H]

Identifier: 91786081

GI number: 91786081

Start: 184025

End: 185926

Strand: Reverse

Name: recQ [H]

Synonym: Bpro_0170

Alternate gene names: 91786081

Gene position: 185926-184025 (Counterclockwise)

Preceding gene: 91786082

Following gene: 91786080

Centisome position: 3.58

GC content: 65.14

Gene sequence:

>1902_bases
TTGTCTTCATCGCCTGTTTCTTCATCCCGGTCTTTATCCCGGCCGACCCCGTTGGACATTCTGGGTCAGGTCTTTGGCTA
CTCCGAGTTCCGCGGCCCGCAGGAAGCCATCGTGGAACACGTGGTGCAGGGCGGCGACGCGCTGGTGCTGATGCCTACCG
GCGGGGGCAAGTCGCTGTGCTATCAGATCCCGGCCATCGTGCGGCAAAACGCCGGCCATGGCGTGACGGTGGTGATTTCG
CCGCTGATTGCGCTGATGCACGACCAGGTCGGCGCGCTGCATGAGGCCGGCGTGTCCGCCGCGTTTTTGAATTCAACGCA
AAGCTTTGAAGAAAGCAGCCAGCTTGAAAAACAGTTGCTGCGCAACGAGCTGACGCTGCTGTACGCGGCGCCCGAACGCA
TCAACACGCCGCGCATGAAGGGCCTGCTGGCCTCGCTGCACGAGCGCGGCCTACTCAGCCTGTTTGCGATCGACGAGGCG
CATTGCGTGAGCCAGTGGGGCCATGATTTCCGGCCGGAGTACCGCTCCCTGAGCCTGCTGCACGAAACCTTTCCCGATGT
GCCGCGCATCGCGCTCACGGCCACCGCCGACGCCCTGACGCGGCAGGACATGATTGAGCGGCTCAAGCTTGAAGACGCGC
GCGAGTTTGTCAGCAGCTTTGACCGGCCCAACATCCGCTACACCATTGTCGAAAAGGCCGACCCGACGCGCCAGCTGCTG
CGCTTCATCGAGTCCGAGCATGAGGGCGAGGCCGGCATTGTGTATTGCCAGTCAAGGAAGCGCGTGGAAGAGATTGCCGC
AACCCTGCAGGATGCCGGCCTGAAGGCGCTGGCTTACCACGCAGGGCTGGACGCCTCGCTGCGCCAGCAGCGGCAAGACC
GCTTCCTGCGCGAGGACGGCGTCGTCATGGTGGCGACAATTGCCTTCGGCATGGGCATTGACAAGCCCGACGTGCGCTTT
GTCGCGCACCTGGACATGCCGAAAAACATCGAAGGCTATTACCAGGAGACGGGCCGGGCCGGGCGCGATGGGCTGCCCGC
CAACGCCTGGATGGCCTACGGCCTGCAGGACGTGGTGAACCAGCGCCGCATGATAGACACCAGCGATGCCGCCAGCGAAG
AGTTCAAGCAGGTGATGCGCGGCAAGCTCGATGCGCTCTTGAGCCTGGCCGAAGACACGCGCTGCCGCCGCGTCAGCCTG
CTGCATTACTTTGACGAGGAAAGCCAACCTTGCGGCAACTGCGACAACTGTCTCAGCCCGCCGGCCGTCTGGGACGCCAC
CGAAGCGGCCCGCAAAATGCTCAGCTGCATCTACCGCGTGCAGCAGGCCAGCGGCATCAGTTTTGGCGCCGGCCACATCA
TGGATATCCTGCGCGGCAAGGCCACCGAGAAAGTGGCGCAATACGGCCACGACAAGCTCAGCACCTTCGGTATTGGCACC
GATCTGGCCGAGGCGCAGTGGCGCAGCGTGCTGCGCCAGCTGATTGCGAAAAACATGGTCCGCGTCGACACGGAAGCCTT
CAGCACGCTGCAGCTGCTGCCCGATGCCCGGCAGGTGCTCAAGGGCGAGGTCAGCGTGGTGCTGCGCGAGCAGGCCCTGG
GCGGCAAGGCCGACCGCCGCAAGCGCGTGACCAAGACCTCCGTCAAGGGCCTGGCCGAAGCCGCGCTCAATGCCGGCGCG
CTGGAACGGCTGGCCAGCCTCAAGGCCTGGCGCGCCGAGGTGGCGCGCGAGCACAACTTGCCGGCGTTCGTGATCTTTCA
CGACGCCACGCTGCGCGCCATTGCCGAGCGCGCACCGCAGCGCCTGCACGACCTGGAAGGGATCAGCGGGATTGGCGCGA
AAAAGCTGGAAGCCTATGGCGCCGAGGTGCTGCGGGTCTGCGTGGCCCCGGCGGCAGGCTGA

Upstream 100 bases:

>100_bases
AGATGTAACCCGCCTTCGGCATCAAATCCGGCTGCAACCCCTGTTTCTTTTGAACTTGCAGCTATTATTTTCATAACAAA
CCTGCATCCGCAGCATCCCC

Downstream 100 bases:

>100_bases
ACGACAGCCGGCCCAGGCCGCCCCTGGCTGTTTTGTTCCCTCGGCTGGCGATCCTCGGCATGGCCGGCATCGTCGCTGCG
ACAGGTGCAGCGTCGCGCTG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MSSSPVSSSRSLSRPTPLDILGQVFGYSEFRGPQEAIVEHVVQGGDALVLMPTGGGKSLCYQIPAIVRQNAGHGVTVVIS
PLIALMHDQVGALHEAGVSAAFLNSTQSFEESSQLEKQLLRNELTLLYAAPERINTPRMKGLLASLHERGLLSLFAIDEA
HCVSQWGHDFRPEYRSLSLLHETFPDVPRIALTATADALTRQDMIERLKLEDAREFVSSFDRPNIRYTIVEKADPTRQLL
RFIESEHEGEAGIVYCQSRKRVEEIAATLQDAGLKALAYHAGLDASLRQQRQDRFLREDGVVMVATIAFGMGIDKPDVRF
VAHLDMPKNIEGYYQETGRAGRDGLPANAWMAYGLQDVVNQRRMIDTSDAASEEFKQVMRGKLDALLSLAEDTRCRRVSL
LHYFDEESQPCGNCDNCLSPPAVWDATEAARKMLSCIYRVQQASGISFGAGHIMDILRGKATEKVAQYGHDKLSTFGIGT
DLAEAQWRSVLRQLIAKNMVRVDTEAFSTLQLLPDARQVLKGEVSVVLREQALGGKADRRKRVTKTSVKGLAEAALNAGA
LERLASLKAWRAEVAREHNLPAFVIFHDATLRAIAERAPQRLHDLEGISGIGAKKLEAYGAEVLRVCVAPAAG

Sequences:

>Translated_633_residues
MSSSPVSSSRSLSRPTPLDILGQVFGYSEFRGPQEAIVEHVVQGGDALVLMPTGGGKSLCYQIPAIVRQNAGHGVTVVIS
PLIALMHDQVGALHEAGVSAAFLNSTQSFEESSQLEKQLLRNELTLLYAAPERINTPRMKGLLASLHERGLLSLFAIDEA
HCVSQWGHDFRPEYRSLSLLHETFPDVPRIALTATADALTRQDMIERLKLEDAREFVSSFDRPNIRYTIVEKADPTRQLL
RFIESEHEGEAGIVYCQSRKRVEEIAATLQDAGLKALAYHAGLDASLRQQRQDRFLREDGVVMVATIAFGMGIDKPDVRF
VAHLDMPKNIEGYYQETGRAGRDGLPANAWMAYGLQDVVNQRRMIDTSDAASEEFKQVMRGKLDALLSLAEDTRCRRVSL
LHYFDEESQPCGNCDNCLSPPAVWDATEAARKMLSCIYRVQQASGISFGAGHIMDILRGKATEKVAQYGHDKLSTFGIGT
DLAEAQWRSVLRQLIAKNMVRVDTEAFSTLQLLPDARQVLKGEVSVVLREQALGGKADRRKRVTKTSVKGLAEAALNAGA
LERLASLKAWRAEVAREHNLPAFVIFHDATLRAIAERAPQRLHDLEGISGIGAKKLEAYGAEVLRVCVAPAAG
>Mature_632_residues
SSSPVSSSRSLSRPTPLDILGQVFGYSEFRGPQEAIVEHVVQGGDALVLMPTGGGKSLCYQIPAIVRQNAGHGVTVVISP
LIALMHDQVGALHEAGVSAAFLNSTQSFEESSQLEKQLLRNELTLLYAAPERINTPRMKGLLASLHERGLLSLFAIDEAH
CVSQWGHDFRPEYRSLSLLHETFPDVPRIALTATADALTRQDMIERLKLEDAREFVSSFDRPNIRYTIVEKADPTRQLLR
FIESEHEGEAGIVYCQSRKRVEEIAATLQDAGLKALAYHAGLDASLRQQRQDRFLREDGVVMVATIAFGMGIDKPDVRFV
AHLDMPKNIEGYYQETGRAGRDGLPANAWMAYGLQDVVNQRRMIDTSDAASEEFKQVMRGKLDALLSLAEDTRCRRVSLL
HYFDEESQPCGNCDNCLSPPAVWDATEAARKMLSCIYRVQQASGISFGAGHIMDILRGKATEKVAQYGHDKLSTFGIGTD
LAEAQWRSVLRQLIAKNMVRVDTEAFSTLQLLPDARQVLKGEVSVVLREQALGGKADRRKRVTKTSVKGLAEAALNAGAL
ERLASLKAWRAEVAREHNLPAFVIFHDATLRAIAERAPQRLHDLEGISGIGAKKLEAYGAEVLRVCVAPAAG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=653, Percent_Identity=34.9157733537519, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI14591902, Length=437, Percent_Identity=37.7574370709382, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI14591904, Length=437, Percent_Identity=37.7574370709382, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI148612816, Length=473, Percent_Identity=38.6892177589852, Blast_Score=275, Evalue=9e-74,
Organism=Homo sapiens, GI110735439, Length=509, Percent_Identity=34.9705304518664, Blast_Score=274, Evalue=2e-73,
Organism=Homo sapiens, GI169218196, Length=509, Percent_Identity=34.9705304518664, Blast_Score=273, Evalue=3e-73,
Organism=Homo sapiens, GI51242947, Length=352, Percent_Identity=43.4659090909091, Blast_Score=259, Evalue=8e-69,
Organism=Homo sapiens, GI51242943, Length=352, Percent_Identity=43.4659090909091, Blast_Score=258, Evalue=9e-69,
Organism=Homo sapiens, GI284005309, Length=378, Percent_Identity=33.0687830687831, Blast_Score=183, Evalue=5e-46,
Organism=Escherichia coli, GI48994977, Length=618, Percent_Identity=45.6310679611651, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI87082221, Length=348, Percent_Identity=24.7126436781609, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788930, Length=330, Percent_Identity=26.3636363636364, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25145561, Length=506, Percent_Identity=39.3280632411067, Blast_Score=345, Evalue=5e-95,
Organism=Caenorhabditis elegans, GI71987993, Length=436, Percent_Identity=37.3853211009174, Blast_Score=296, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI71987997, Length=436, Percent_Identity=37.3853211009174, Blast_Score=296, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI32564293, Length=680, Percent_Identity=31.6176470588235, Blast_Score=294, Evalue=9e-80,
Organism=Caenorhabditis elegans, GI17552866, Length=448, Percent_Identity=37.7232142857143, Blast_Score=281, Evalue=9e-76,
Organism=Caenorhabditis elegans, GI17555296, Length=353, Percent_Identity=24.929178470255, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=528, Percent_Identity=36.9318181818182, Blast_Score=358, Evalue=2e-99,
Organism=Saccharomyces cerevisiae, GI6324217, Length=330, Percent_Identity=25.7575757575758, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646066, Length=641, Percent_Identity=35.4134165366615, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24664226, Length=435, Percent_Identity=37.7011494252874, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24664230, Length=440, Percent_Identity=37.2727272727273, Blast_Score=272, Evalue=5e-73,
Organism=Drosophila melanogaster, GI62472181, Length=440, Percent_Identity=37.2727272727273, Blast_Score=272, Evalue=5e-73,
Organism=Drosophila melanogaster, GI21358123, Length=354, Percent_Identity=36.1581920903955, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI28574962, Length=342, Percent_Identity=26.0233918128655, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 69675; Mature: 69544

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSPVSSSRSLSRPTPLDILGQVFGYSEFRGPQEAIVEHVVQGGDALVLMPTGGGKSLC
CCCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCHHHHHHHHHHCCCCEEEEEECCCCCHHH
YQIPAIVRQNAGHGVTVVISPLIALMHDQVGALHEAGVSAAFLNSTQSFEESSQLEKQLL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHH
RNELTLLYAAPERINTPRMKGLLASLHERGLLSLFAIDEAHCVSQWGHDFRPEYRSLSLL
HHHHEEEEECCHHCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHH
HETFPDVPRIALTATADALTRQDMIERLKLEDAREFVSSFDRPNIRYTIVEKADPTRQLL
HHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
RFIESEHEGEAGIVYCQSRKRVEEIAATLQDAGLKALAYHAGLDASLRQQRQDRFLREDG
HHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCC
VVMVATIAFGMGIDKPDVRFVAHLDMPKNIEGYYQETGRAGRDGLPANAWMAYGLQDVVN
CEEEEEHHHHCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
QRRMIDTSDAASEEFKQVMRGKLDALLSLAEDTRCRRVSLLHYFDEESQPCGNCDNCLSP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PAVWDATEAARKMLSCIYRVQQASGISFGAGHIMDILRGKATEKVAQYGHDKLSTFGIGT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHCCCHHHHHCCCCC
DLAEAQWRSVLRQLIAKNMVRVDTEAFSTLQLLPDARQVLKGEVSVVLREQALGGKADRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
KRVTKTSVKGLAEAALNAGALERLASLKAWRAEVAREHNLPAFVIFHDATLRAIAERAPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
RLHDLEGISGIGAKKLEAYGAEVLRVCVAPAAG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSSPVSSSRSLSRPTPLDILGQVFGYSEFRGPQEAIVEHVVQGGDALVLMPTGGGKSLC
CCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCHHHHHHHHHHCCCCEEEEEECCCCCHHH
YQIPAIVRQNAGHGVTVVISPLIALMHDQVGALHEAGVSAAFLNSTQSFEESSQLEKQLL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHH
RNELTLLYAAPERINTPRMKGLLASLHERGLLSLFAIDEAHCVSQWGHDFRPEYRSLSLL
HHHHEEEEECCHHCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHH
HETFPDVPRIALTATADALTRQDMIERLKLEDAREFVSSFDRPNIRYTIVEKADPTRQLL
HHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
RFIESEHEGEAGIVYCQSRKRVEEIAATLQDAGLKALAYHAGLDASLRQQRQDRFLREDG
HHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCC
VVMVATIAFGMGIDKPDVRFVAHLDMPKNIEGYYQETGRAGRDGLPANAWMAYGLQDVVN
CEEEEEHHHHCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
QRRMIDTSDAASEEFKQVMRGKLDALLSLAEDTRCRRVSLLHYFDEESQPCGNCDNCLSP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PAVWDATEAARKMLSCIYRVQQASGISFGAGHIMDILRGKATEKVAQYGHDKLSTFGIGT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHCCCHHHHHCCCCC
DLAEAQWRSVLRQLIAKNMVRVDTEAFSTLQLLPDARQVLKGEVSVVLREQALGGKADRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
KRVTKTSVKGLAEAALNAGALERLASLKAWRAEVAREHNLPAFVIFHDATLRAIAERAPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
RLHDLEGISGIGAKKLEAYGAEVLRVCVAPAAG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]