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The map label for this gene is putA [H]

Identifier: 91785724

GI number: 91785724

Start: 4790785

End: 4794714

Strand: Reverse

Name: putA [H]

Synonym: Bxe_A0049

Alternate gene names: 91785724

Gene position: 4794714-4790785 (Counterclockwise)

Preceding gene: 91785725

Following gene: 91785723

Centisome position: 97.93

GC content: 65.8

Gene sequence:

>3930_bases
ATGGCTAGCACCACCCTTGGCGTCAAGGTCGACGACCTCTTGCGTTCCCGGCTGAAAGATGCCGCTACCCGTCTCGAACG
CACTCCGCACTGGCTCATCAAGCAGGCCATCTTCGCGTACCTCGAAAAGATCGAGCACGGTCAATTGCCGCCCGAGCTGT
CGGGTGTGGCGGGCTCGGCCGATCTGACCGAGGGCGCCGCGGTCGAACACGAGGAAGACGGTGGGTCGCACCCGTTCCTC
GATTTCGCGCAAAACGTGCAACCGCAATCGGTGCTGCGCGCCGCGATCACGGCCGCTTACCGTCGTCCTGAGCCGGAGTG
TTTGCCGTTCCTGCTCGGTCAGGCGCGTTTGCCGGCCAACCTCGCGGGCGACGTGCAGACGATGGCCGGCAAGCTCGTCG
AAACGCTGCGCACGAAGAGCAAGGGCGGTGGCGTCGAAGGTCTGATCCACGAGTTCTCGCTGTCGAGCCAGGAAGGCGTG
GCGCTGATGTGTCTCGCCGAAGCGCTGCTGCGCATTCCCGACCGCGCCACGCGCGACGCGCTGATCCGCGACAAGATCAG
CAAGGGCGACTGGAAATCGCACATGGGCCAGGCGCCGTCGATGTTCGTCAACGCCGCGACCTGGGGCTTGATGATCACCG
GCAAGCTGGTGACGACCAACAGCGAGACGAGCCTCTCGTCGGCGCTCACGCGTCTGATCGGCAAGGGCGGCGAGCCGCTG
ATCCGCAAGGGCGTGGATATGGCAATGCGCCTGATGGGCGAGCAGTTCGTCACGGGTGAGAACATCTCCGAGGCGCTCGC
CAACAGCCGCAAGTACGAAGCCCGCGGCTTCCGCTACTCGTACGACATGCTCGGCGAAGCGGCCACCACCGAAGCCGACG
CGCAGCGCTACTACGCGTCGTACGAACAGGCGATCCACGCGATCGGCAAGGCTGCCGGCGGCCGTGGCATCTACGAAGGC
CCGGGCATTTCGATCAAGCTCTCCGCGCTGCACGCACGCTACTCGCGTTCGCAGCAGGAACGCACCATGAGCGAACTGCT
GCCGCGCGTGCGCTCGCTGGCAATCCTCGCGCGCCGCTACGACATCGGCCTGAACATCGACGCGGAAGAAGCCGACCGCC
TCGAAATCTCGCTCGATCTGCTCGAAGCGCTGTGCTTCGATCCGGAGCTGGCCGGCTGGAACGGCATCGGCTTCGTGGTG
CAGGCGTATCAGAAGCGCTGCCCGTTCGTGATCGAATACCTGATCGATCTGGCGCGCCGCAGCCGTCACCGCATCATGGT
GCGCCTCGTGAAGGGCGCGTACTGGGACACCGAAATCAAGCGCGCGCAAGTGGACGGCCTCGAAGGCTATCCGGTCTACA
CGCGCAAGATCTACACAGACGTGTCGTATCTCGCCTGCGCGAAGAAACTGCTCAGCGCGCCCGACGCGGTCTACCCGCAA
TTCGCCACGCACAACGCGCACACGCTGTCGGCGATCTATCACCTCGCGGGCAACAACTATTACCCCGGCCAGTACGAGTT
CCAGTGCCTGCACGGCATGGGCGAACCGCTGTACGAAGAAGTCACCGGCCGCGACAAGCTGAACCGTCCGTGCCGGGTGT
ACGCGCCGGTCGGCACGCATGAAACGCTGCTTGCCTATCTCGTGCGCCGTCTGCTGGAAAACGGCGCGAACACGTCGTTC
GTGAATCGTATTGCCGATGAAACCGTCGCGATCAAGGACCTGATCGCCGATCCGGTCGATGAAGCCTCGAAGATCGTCCC
GCTCGGCGCGCCGCACGCGAAGATTCCGCTGCCGCGCAATCTGTACGGTTCGGAACGCCTCAACTCGATGGGTCTCGACC
TGTCGAACGAGCATCGCCTGGCGTCGCTGTCGTCGGCGTTGCTGGCGAGCGCGCATCATCCGTGGCGCGCCGCGCCGATG
CTCGAAGACAACGAGATCGCCGTGGGCCTCGCGCGCGACGTGCGCAATCCGGCCGATCATCGCGACCTCGTCGGCACGGT
CGTGGAAACGACGCCGGAGCACGTGAGCGCCGCTTTGGCGCACGCGGTGGCCGCCGCGCCGATCTGGCAAGCCACGCCGG
TCGATGCGCGCGCCGATTGCCTCGCGCGTGCCGCCGATCTGCTCGAAGCGCAGATGCATACGCTGATGGGCCTCGTGGTG
CGTGAAGCCGGCAAGTCGCTGGCCAACGCCGTCGCGGAAATTCGCGAAGCGATCGACTTCCTGCGTTACTACTCCACGCA
GATTCGCGAGGAGTTCTCCAACGACACGCATCGTCCGCTCGGCCCGGTGGTCTGTATCAGCCCGTGGAATTTCCCGCTGG
CGATTTTCATGGGCCAGGTGGCCGCGGCGCTCGCCGCCGGCAACACCGTGCTCGCGAAGCCGGCCGAACAGACGCCGCTG
ATCGCCGCGCAAGCCGTGCGCATTCTACGCGAAGCCGGCGTGCCGGCGGGCGCGGTGCAACTGCTGCCGGGCAACGGTGA
AACGGTCGGCGCCGCATTGGTGGCCGATCCGCGCACCCGCGCGGTGATGTTCACCGGCTCGACCGAAGTCGCACGCCTCA
TCAACAAGACGCTGTCGAGCCGACTCGATCCGGATGGCAAGCCGATTCCGCTGATCGCCGAAACGGGCGGCCAGAACGCG
ATGATCGTCGACTCGTCGGCGCTTGCCGAACAGGTGGTGGCGGACGTGCTGCAATCGTCGTTCGACTCCGCCGGTCAACG
GTGTTCCGCGCTGCGCGTTCTTTGTCTGCAGGACGATGTCGCGGACCGCACGCTGGAAATGCTGACCGGCGCGATGCGCG
AACTGGCCGTGGGCAATCCGGACCGTCTGTCGGTCGACGTCGGCCCGGTGATCGACCTCGACGCGAAGCGCGGTATCGAC
GCGCACGTCGCGGCGATGCGCGAGAAGGGCCGCAAGGTCGAGCAGCTGCCGATGCCGGACGGTTGCGCGCAAGGCACCTT
CGTGCCGCCGACGTTGATCGAACTCGACAGCATCGACGAACTGAAGCGTGAAGTGTTCGGCCCGGTGCTGCACGTGGTGC
GCTACCGCCGCAGCCAGCTGGACAAACTGCTGGAGCAGATCCGCGCGACCGGCTATGGCCTGACGCTCGGCATCCATACG
CGTATCGACGAAACGATCGCGCATGTGATCAGCCGCGCGCACGTGGGCAACATCTACGTGAACCGGAACGTGATCGGCGC
TGTGGTCGGCGTGCAGCCGTTCGGTGGCGAAGGTTTGTCGGGCACGGGTCCGAAAGCGGGCGGCGCGCTCTATCTGCAGC
GGCTCCTCGCCACGCGTCCGGCCGGTTTGCCGAAGTCGCTTGCGCGGGCTTTGGTCGTGGATGTTCCGCGCGCGGCCGAA
AACGGCGACAATCCGTCCGCTGTATTGACGGCTTACCGCGACTGGCTGATTACCGAACGCGAGCCGCAACTGGCCGCGCG
CTGCGACGGCTATCTGTCGCATGTGCCGGCGGGCGCCACGGCGGTATTGTCGGGACCGACCGGCGAGCGCAACACGTACA
CGCTGGGCGCGCGCGGCACGGTGCTGTGTATCGCGTCGACGGCGAGCGGTGCGCGCGTGCAGTTTGCCGCGGCGCTGGCT
ACGGGAAATCGCGCGTTGTTCGAAGGCGCGGCTGGGGAACAATTGGTGTCGCAGTTGCCCGCCTCGCTGAAGTCGCACGC
AAGCGTGAAGAAGAGTGCCGATACGCCGTTCGACGCCGTGCTGTTCGAAGGCGATAGCGACGAACTGCTGGCGCTGGTGA
AGGAAGTCGCGAAGCGTCCAGGCCCGATCGTGTCGGTACAGGGCGTCGCGGCACGCGCGCTGGAAAGCGGCGACGAGGAC
TACGCGCTCGAGCGTCTGTTGACGGAACGCTCGGTCAGCGTCAATACGGCAGCTGCAGGCGGTAATGCGAATTTGATGAC
GATCGGTTGA

Upstream 100 bases:

>100_bases
ATGCATCCGACATGGTTGCACCTTTTTATTGGGAGGCGTACGATTCGCCCAACTTTTAGTCTTTTGCCAGCGTATCTGTC
TGGTATCCGAAGAAGGAAAC

Downstream 100 bases:

>100_bases
GCGAACCTCTCTGATCACTCAAAAAAACGGAAGCGGTACGGCGACCCCGAAACCGCTCCATCCACACCTGGTACCAAGGA
GAAGCTATGCAACACAAGAT

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1309; Mature: 1308

Protein sequence:

>1309_residues
MASTTLGVKVDDLLRSRLKDAATRLERTPHWLIKQAIFAYLEKIEHGQLPPELSGVAGSADLTEGAAVEHEEDGGSHPFL
DFAQNVQPQSVLRAAITAAYRRPEPECLPFLLGQARLPANLAGDVQTMAGKLVETLRTKSKGGGVEGLIHEFSLSSQEGV
ALMCLAEALLRIPDRATRDALIRDKISKGDWKSHMGQAPSMFVNAATWGLMITGKLVTTNSETSLSSALTRLIGKGGEPL
IRKGVDMAMRLMGEQFVTGENISEALANSRKYEARGFRYSYDMLGEAATTEADAQRYYASYEQAIHAIGKAAGGRGIYEG
PGISIKLSALHARYSRSQQERTMSELLPRVRSLAILARRYDIGLNIDAEEADRLEISLDLLEALCFDPELAGWNGIGFVV
QAYQKRCPFVIEYLIDLARRSRHRIMVRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLSAPDAVYPQ
FATHNAHTLSAIYHLAGNNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSF
VNRIADETVAIKDLIADPVDEASKIVPLGAPHAKIPLPRNLYGSERLNSMGLDLSNEHRLASLSSALLASAHHPWRAAPM
LEDNEIAVGLARDVRNPADHRDLVGTVVETTPEHVSAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLVV
REAGKSLANAVAEIREAIDFLRYYSTQIREEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPL
IAAQAVRILREAGVPAGAVQLLPGNGETVGAALVADPRTRAVMFTGSTEVARLINKTLSSRLDPDGKPIPLIAETGGQNA
MIVDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLEMLTGAMRELAVGNPDRLSVDVGPVIDLDAKRGID
AHVAAMREKGRKVEQLPMPDGCAQGTFVPPTLIELDSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHT
RIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPKSLARALVVDVPRAAE
NGDNPSAVLTAYRDWLITEREPQLAARCDGYLSHVPAGATAVLSGPTGERNTYTLGARGTVLCIASTASGARVQFAAALA
TGNRALFEGAAGEQLVSQLPASLKSHASVKKSADTPFDAVLFEGDSDELLALVKEVAKRPGPIVSVQGVAARALESGDED
YALERLLTERSVSVNTAAAGGNANLMTIG

Sequences:

>Translated_1309_residues
MASTTLGVKVDDLLRSRLKDAATRLERTPHWLIKQAIFAYLEKIEHGQLPPELSGVAGSADLTEGAAVEHEEDGGSHPFL
DFAQNVQPQSVLRAAITAAYRRPEPECLPFLLGQARLPANLAGDVQTMAGKLVETLRTKSKGGGVEGLIHEFSLSSQEGV
ALMCLAEALLRIPDRATRDALIRDKISKGDWKSHMGQAPSMFVNAATWGLMITGKLVTTNSETSLSSALTRLIGKGGEPL
IRKGVDMAMRLMGEQFVTGENISEALANSRKYEARGFRYSYDMLGEAATTEADAQRYYASYEQAIHAIGKAAGGRGIYEG
PGISIKLSALHARYSRSQQERTMSELLPRVRSLAILARRYDIGLNIDAEEADRLEISLDLLEALCFDPELAGWNGIGFVV
QAYQKRCPFVIEYLIDLARRSRHRIMVRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLSAPDAVYPQ
FATHNAHTLSAIYHLAGNNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSF
VNRIADETVAIKDLIADPVDEASKIVPLGAPHAKIPLPRNLYGSERLNSMGLDLSNEHRLASLSSALLASAHHPWRAAPM
LEDNEIAVGLARDVRNPADHRDLVGTVVETTPEHVSAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLVV
REAGKSLANAVAEIREAIDFLRYYSTQIREEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPL
IAAQAVRILREAGVPAGAVQLLPGNGETVGAALVADPRTRAVMFTGSTEVARLINKTLSSRLDPDGKPIPLIAETGGQNA
MIVDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLEMLTGAMRELAVGNPDRLSVDVGPVIDLDAKRGID
AHVAAMREKGRKVEQLPMPDGCAQGTFVPPTLIELDSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHT
RIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPKSLARALVVDVPRAAE
NGDNPSAVLTAYRDWLITEREPQLAARCDGYLSHVPAGATAVLSGPTGERNTYTLGARGTVLCIASTASGARVQFAAALA
TGNRALFEGAAGEQLVSQLPASLKSHASVKKSADTPFDAVLFEGDSDELLALVKEVAKRPGPIVSVQGVAARALESGDED
YALERLLTERSVSVNTAAAGGNANLMTIG
>Mature_1308_residues
ASTTLGVKVDDLLRSRLKDAATRLERTPHWLIKQAIFAYLEKIEHGQLPPELSGVAGSADLTEGAAVEHEEDGGSHPFLD
FAQNVQPQSVLRAAITAAYRRPEPECLPFLLGQARLPANLAGDVQTMAGKLVETLRTKSKGGGVEGLIHEFSLSSQEGVA
LMCLAEALLRIPDRATRDALIRDKISKGDWKSHMGQAPSMFVNAATWGLMITGKLVTTNSETSLSSALTRLIGKGGEPLI
RKGVDMAMRLMGEQFVTGENISEALANSRKYEARGFRYSYDMLGEAATTEADAQRYYASYEQAIHAIGKAAGGRGIYEGP
GISIKLSALHARYSRSQQERTMSELLPRVRSLAILARRYDIGLNIDAEEADRLEISLDLLEALCFDPELAGWNGIGFVVQ
AYQKRCPFVIEYLIDLARRSRHRIMVRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLSAPDAVYPQF
ATHNAHTLSAIYHLAGNNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFV
NRIADETVAIKDLIADPVDEASKIVPLGAPHAKIPLPRNLYGSERLNSMGLDLSNEHRLASLSSALLASAHHPWRAAPML
EDNEIAVGLARDVRNPADHRDLVGTVVETTPEHVSAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLVVR
EAGKSLANAVAEIREAIDFLRYYSTQIREEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLI
AAQAVRILREAGVPAGAVQLLPGNGETVGAALVADPRTRAVMFTGSTEVARLINKTLSSRLDPDGKPIPLIAETGGQNAM
IVDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLEMLTGAMRELAVGNPDRLSVDVGPVIDLDAKRGIDA
HVAAMREKGRKVEQLPMPDGCAQGTFVPPTLIELDSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHTR
IDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPKSLARALVVDVPRAAEN
GDNPSAVLTAYRDWLITEREPQLAARCDGYLSHVPAGATAVLSGPTGERNTYTLGARGTVLCIASTASGARVQFAAALAT
GNRALFEGAAGEQLVSQLPASLKSHASVKKSADTPFDAVLFEGDSDELLALVKEVAKRPGPIVSVQGVAARALESGDEDY
ALERLLTERSVSVNTAAAGGNANLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=453, Percent_Identity=32.2295805739514, Blast_Score=188, Evalue=3e-47,
Organism=Homo sapiens, GI153266822, Length=415, Percent_Identity=30.6024096385542, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI25777732, Length=447, Percent_Identity=30.6487695749441, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI25777736, Length=478, Percent_Identity=30.1255230125523, Blast_Score=170, Evalue=1e-41,
Organism=Homo sapiens, GI25777734, Length=478, Percent_Identity=30.1255230125523, Blast_Score=170, Evalue=1e-41,
Organism=Homo sapiens, GI25777724, Length=496, Percent_Identity=28.2258064516129, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI238859541, Length=478, Percent_Identity=30.1255230125523, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI25777730, Length=443, Percent_Identity=30.2483069977427, Blast_Score=167, Evalue=6e-41,
Organism=Homo sapiens, GI25777728, Length=405, Percent_Identity=29.8765432098765, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI21614513, Length=431, Percent_Identity=30.3944315545244, Blast_Score=162, Evalue=3e-39,
Organism=Homo sapiens, GI12007648, Length=433, Percent_Identity=29.5612009237875, Blast_Score=160, Evalue=8e-39,
Organism=Homo sapiens, GI238814322, Length=430, Percent_Identity=26.9767441860465, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI4507229, Length=502, Percent_Identity=28.6852589641434, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI11095441, Length=429, Percent_Identity=27.972027972028, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI115387104, Length=449, Percent_Identity=26.5033407572383, Blast_Score=138, Evalue=4e-32,
Organism=Homo sapiens, GI25777721, Length=515, Percent_Identity=27.9611650485437, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI310128093, Length=438, Percent_Identity=28.310502283105, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI310128103, Length=440, Percent_Identity=27.7272727272727, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI188035924, Length=440, Percent_Identity=27.7272727272727, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI25952152, Length=427, Percent_Identity=28.5714285714286, Blast_Score=128, Evalue=3e-29,
Organism=Homo sapiens, GI25777726, Length=496, Percent_Identity=24.7983870967742, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI310128091, Length=404, Percent_Identity=27.970297029703, Blast_Score=117, Evalue=8e-26,
Organism=Homo sapiens, GI310128087, Length=248, Percent_Identity=30.241935483871, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI71773324, Length=387, Percent_Identity=25.3229974160207, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI206597441, Length=436, Percent_Identity=24.0825688073394, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI206597439, Length=436, Percent_Identity=24.0825688073394, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI22907049, Length=436, Percent_Identity=24.0825688073394, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI4502043, Length=331, Percent_Identity=25.3776435045317, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI238814371, Length=331, Percent_Identity=25.3776435045317, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI310128089, Length=341, Percent_Identity=26.3929618768328, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI301500698, Length=421, Percent_Identity=25.1781472684086, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI310128095, Length=327, Percent_Identity=26.605504587156, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI73695881, Length=383, Percent_Identity=23.4986945169713, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI73695879, Length=383, Percent_Identity=23.4986945169713, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128101, Length=195, Percent_Identity=29.7435897435897, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI310128099, Length=194, Percent_Identity=29.8969072164948, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI4557303, Length=353, Percent_Identity=23.2294617563739, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI73466520, Length=353, Percent_Identity=23.2294617563739, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI310128097, Length=274, Percent_Identity=26.6423357664234, Blast_Score=76, Evalue=2e-13,
Organism=Escherichia coli, GI1787250, Length=1331, Percent_Identity=66.190833959429, Blast_Score=1725, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=465, Percent_Identity=32.0430107526882, Blast_Score=185, Evalue=2e-47,
Organism=Escherichia coli, GI1787684, Length=458, Percent_Identity=29.6943231441048, Blast_Score=160, Evalue=4e-40,
Organism=Escherichia coli, GI1787715, Length=454, Percent_Identity=31.7180616740088, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI1788042, Length=450, Percent_Identity=30, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI87081896, Length=420, Percent_Identity=29.7619047619048, Blast_Score=147, Evalue=5e-36,
Organism=Escherichia coli, GI1786504, Length=457, Percent_Identity=29.3216630196937, Blast_Score=144, Evalue=5e-35,
Organism=Escherichia coli, GI1787558, Length=414, Percent_Identity=30.4347826086957, Blast_Score=141, Evalue=3e-34,
Organism=Escherichia coli, GI87082295, Length=458, Percent_Identity=27.7292576419214, Blast_Score=133, Evalue=7e-32,
Organism=Escherichia coli, GI87081926, Length=425, Percent_Identity=25.4117647058824, Blast_Score=118, Evalue=3e-27,
Organism=Escherichia coli, GI1787653, Length=378, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17534447, Length=475, Percent_Identity=31.1578947368421, Blast_Score=189, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI25144435, Length=454, Percent_Identity=31.7180616740088, Blast_Score=169, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI32564736, Length=410, Percent_Identity=32.4390243902439, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI115532534, Length=375, Percent_Identity=32.2666666666667, Blast_Score=161, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17562198, Length=492, Percent_Identity=28.8617886178862, Blast_Score=160, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI115534176, Length=443, Percent_Identity=30.4740406320542, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32564151, Length=426, Percent_Identity=29.1079812206573, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI133930964, Length=435, Percent_Identity=28.2758620689655, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25143874, Length=500, Percent_Identity=25.4, Blast_Score=139, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25143876, Length=501, Percent_Identity=25.5489021956088, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71986308, Length=427, Percent_Identity=27.6346604215457, Blast_Score=134, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17551164, Length=451, Percent_Identity=25.2771618625277, Blast_Score=133, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17534119, Length=459, Percent_Identity=26.3616557734205, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=316, Percent_Identity=28.7974683544304, Blast_Score=117, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71995606, Length=445, Percent_Identity=26.0674157303371, Blast_Score=117, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71995613, Length=402, Percent_Identity=25.6218905472637, Blast_Score=111, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32566756, Length=411, Percent_Identity=22.6277372262774, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25146394, Length=411, Percent_Identity=22.6277372262774, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25146391, Length=411, Percent_Identity=22.6277372262774, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17564084, Length=343, Percent_Identity=25.0728862973761, Blast_Score=88, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320917, Length=457, Percent_Identity=32.1663019693654, Blast_Score=187, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6321826, Length=482, Percent_Identity=30.2904564315353, Blast_Score=176, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6323821, Length=427, Percent_Identity=31.3817330210773, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6325196, Length=420, Percent_Identity=30.7142857142857, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323822, Length=435, Percent_Identity=29.8850574712644, Blast_Score=164, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6324950, Length=414, Percent_Identity=28.5024154589372, Blast_Score=162, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6319478, Length=454, Percent_Identity=26.6519823788546, Blast_Score=131, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=475, Percent_Identity=24, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323757, Length=328, Percent_Identity=25, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24668425, Length=490, Percent_Identity=28.1632653061224, Blast_Score=171, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24668417, Length=490, Percent_Identity=28.1632653061224, Blast_Score=171, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24668413, Length=490, Percent_Identity=28.1632653061224, Blast_Score=171, Evalue=4e-42,
Organism=Drosophila melanogaster, GI20129399, Length=416, Percent_Identity=31.0096153846154, Blast_Score=168, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281362580, Length=456, Percent_Identity=28.7280701754386, Blast_Score=167, Evalue=4e-41,
Organism=Drosophila melanogaster, GI62472918, Length=456, Percent_Identity=28.7280701754386, Blast_Score=167, Evalue=4e-41,
Organism=Drosophila melanogaster, GI62472926, Length=456, Percent_Identity=28.7280701754386, Blast_Score=167, Evalue=4e-41,
Organism=Drosophila melanogaster, GI62472936, Length=456, Percent_Identity=28.7280701754386, Blast_Score=167, Evalue=4e-41,
Organism=Drosophila melanogaster, GI21356737, Length=456, Percent_Identity=28.7280701754386, Blast_Score=167, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24650465, Length=449, Percent_Identity=28.2850779510022, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI28574525, Length=490, Percent_Identity=27.3469387755102, Blast_Score=153, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24666674, Length=436, Percent_Identity=30.045871559633, Blast_Score=146, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24585660, Length=462, Percent_Identity=25.7575757575758, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571802, Length=470, Percent_Identity=26.1702127659574, Blast_Score=144, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28571800, Length=470, Percent_Identity=26.1702127659574, Blast_Score=144, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28571798, Length=470, Percent_Identity=26.1702127659574, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28571796, Length=470, Percent_Identity=26.1702127659574, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28571794, Length=470, Percent_Identity=26.1702127659574, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28571806, Length=470, Percent_Identity=26.1702127659574, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24638878, Length=428, Percent_Identity=26.8691588785047, Blast_Score=117, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24638876, Length=428, Percent_Identity=26.8691588785047, Blast_Score=116, Evalue=9e-26,
Organism=Drosophila melanogaster, GI281360299, Length=337, Percent_Identity=27.299703264095, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360297, Length=337, Percent_Identity=27.299703264095, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360295, Length=337, Percent_Identity=27.299703264095, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586250, Length=337, Percent_Identity=27.299703264095, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360301, Length=333, Percent_Identity=26.7267267267267, Blast_Score=92, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281360303, Length=333, Percent_Identity=25.5255255255255, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45552499, Length=337, Percent_Identity=25.5192878338279, Blast_Score=86, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 140853; Mature: 140722

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTTLGVKVDDLLRSRLKDAATRLERTPHWLIKQAIFAYLEKIEHGQLPPELSGVAGSA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCC
DLTEGAAVEHEEDGGSHPFLDFAQNVQPQSVLRAAITAAYRRPEPECLPFLLGQARLPAN
CCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCC
LAGDVQTMAGKLVETLRTKSKGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHH
LIRDKISKGDWKSHMGQAPSMFVNAATWGLMITGKLVTTNSETSLSSALTRLIGKGGEPL
HHHHHCCCCCHHHHCCCCCHHHHHHHHEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCHH
IRKGVDMAMRLMGEQFVTGENISEALANSRKYEARGFRYSYDMLGEAATTEADAQRYYAS
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEHHHHCCHHCCHHHHHHHHHH
YEQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQERTMSELLPRVRSLAILARRY
HHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGLNIDAEEADRLEISLDLLEALCFDPELAGWNGIGFVVQAYQKRCPFVIEYLIDLARR
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
SRHRIMVRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLSAPDAVYPQ
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FATHNAHTLSAIYHLAGNNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTH
HHCCCHHHHHHHHHHHCCCCCCCCEEHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCH
ETLLAYLVRRLLENGANTSFVNRIADETVAIKDLIADPVDEASKIVPLGAPHAKIPLPRN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCEEECCCCCCCCCCCCC
LYGSERLNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLEDNEIAVGLARDVRNPADH
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHCCCCCHH
RDLVGTVVETTPEHVSAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLVV
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
REAGKSLANAVAEIREAIDFLRYYSTQIREEFSNDTHRPLGPVVCISPWNFPLAIFMGQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHH
AAALAAGNTVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGNGETVGAALVADPRTR
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEECCCCC
AVMFTGSTEVARLINKTLSSRLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVLQSS
EEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
FDSAGQRCSALRVLCLQDDVADRTLEMLTGAMRELAVGNPDRLSVDVGPVIDLDAKRGID
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCH
AHVAAMREKGRKVEQLPMPDGCAQGTFVPPTLIELDSIDELKREVFGPVLHVVRYRRSQL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHH
DKLLEQIRATGYGLTLGIHTRIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLS
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCCCC
GTGPKAGGALYLQRLLATRPAGLPKSLARALVVDVPRAAENGDNPSAVLTAYRDWLITER
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC
EPQLAARCDGYLSHVPAGATAVLSGPTGERNTYTLGARGTVLCIASTASGARVQFAAALA
CCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCEEEEEEECCCCCEEEEEHHHH
TGNRALFEGAAGEQLVSQLPASLKSHASVKKSADTPFDAVLFEGDSDELLALVKEVAKRP
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCC
GPIVSVQGVAARALESGDEDYALERLLTERSVSVNTAAAGGNANLMTIG
CCEEEECHHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC
>Mature Secondary Structure 
ASTTLGVKVDDLLRSRLKDAATRLERTPHWLIKQAIFAYLEKIEHGQLPPELSGVAGSA
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCC
DLTEGAAVEHEEDGGSHPFLDFAQNVQPQSVLRAAITAAYRRPEPECLPFLLGQARLPAN
CCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCC
LAGDVQTMAGKLVETLRTKSKGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHH
LIRDKISKGDWKSHMGQAPSMFVNAATWGLMITGKLVTTNSETSLSSALTRLIGKGGEPL
HHHHHCCCCCHHHHCCCCCHHHHHHHHEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCHH
IRKGVDMAMRLMGEQFVTGENISEALANSRKYEARGFRYSYDMLGEAATTEADAQRYYAS
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEHHHHCCHHCCHHHHHHHHHH
YEQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQERTMSELLPRVRSLAILARRY
HHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGLNIDAEEADRLEISLDLLEALCFDPELAGWNGIGFVVQAYQKRCPFVIEYLIDLARR
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
SRHRIMVRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLSAPDAVYPQ
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FATHNAHTLSAIYHLAGNNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTH
HHCCCHHHHHHHHHHHCCCCCCCCEEHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCH
ETLLAYLVRRLLENGANTSFVNRIADETVAIKDLIADPVDEASKIVPLGAPHAKIPLPRN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCEEECCCCCCCCCCCCC
LYGSERLNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLEDNEIAVGLARDVRNPADH
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHCCCCCHH
RDLVGTVVETTPEHVSAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLVV
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
REAGKSLANAVAEIREAIDFLRYYSTQIREEFSNDTHRPLGPVVCISPWNFPLAIFMGQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHH
AAALAAGNTVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGNGETVGAALVADPRTR
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEECCCCC
AVMFTGSTEVARLINKTLSSRLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVLQSS
EEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
FDSAGQRCSALRVLCLQDDVADRTLEMLTGAMRELAVGNPDRLSVDVGPVIDLDAKRGID
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCH
AHVAAMREKGRKVEQLPMPDGCAQGTFVPPTLIELDSIDELKREVFGPVLHVVRYRRSQL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHH
DKLLEQIRATGYGLTLGIHTRIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLS
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCCCC
GTGPKAGGALYLQRLLATRPAGLPKSLARALVVDVPRAAENGDNPSAVLTAYRDWLITER
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC
EPQLAARCDGYLSHVPAGATAVLSGPTGERNTYTLGARGTVLCIASTASGARVQFAAALA
CCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCEEEEEEECCCCCEEEEEHHHH
TGNRALFEGAAGEQLVSQLPASLKSHASVKKSADTPFDAVLFEGDSDELLALVKEVAKRP
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCC
GPIVSVQGVAARALESGDEDYALERLLTERSVSVNTAAAGGNANLMTIG
CCEEEECHHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]