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The map label for this gene is cheB

Identifier: 91785653

GI number: 91785653

Start: 4710523

End: 4711611

Strand: Reverse

Name: cheB

Synonym: Bxe_A0124

Alternate gene names: 91785653

Gene position: 4711611-4710523 (Counterclockwise)

Preceding gene: 91785654

Following gene: 91785652

Centisome position: 96.24

GC content: 65.2

Gene sequence:

>1089_bases
GTGCAAAAGATCAAGGTACTGTGCGTCGACGATTCGGCGCTGATCCGCAGCCTGATGACGGAAATCATCAACGGCCAGCC
GGACATGACGGTGGTGGCGACCGCACCCGACCCGCTGGTCGCGCGCGAACTCATCAAGCAGCACAATCCGGACGTGCTGA
CGCTCGACGTCGAAATGCCGCGCATGGACGGCCTCGACTTCCTCGAGAAGCTGATGCGCCTGCGGCCGATGCCCGTGGTG
ATGGTGTCGTCGCTGACCGAGCGCGGCAACGAAATCACGCTGCGCGCGCTGGAACTCGGCGCGGTCGACTTCGTCACCAA
GCCGAAGGTCGGCATTCGCGACGGCATGCTCGACTATTCGGAAAAGCTCGCCGACAAGATTCGCGCGGCGGCCCGCGCGC
GCGTGCGCCAGAGCGCGCCGGTGCAGCACGCGGCCGCTCATGCCGCGCATGCGCCGGTCGGCGCGGCGCCGCTGTTCAAT
AATCCGCTGCTCAGTACCGAGAAGCTGATTATCGTCGGCGCGTCGACGGGCGGCACGGAAGCGATCCGCGAAGTGCTGGT
GCCGCTGCCGCCGGATGCGCCCGCGGTGCTGATCGCGCAGCATATGCCGCCGGGCTTCACAAAATCTTTTGCGCAACGCC
TCAATGGTTTGTGCCGGATTACCGTTAAAGAGGCAGAGCACGGCGAACGCGTGCTGCCCGGGCATGCCTATATCGCGCCT
GGCCACGCTCACCTGTTGCTTGCCCGCAGTGGCGCGAACTATATTGCTCACCTTTCGGACGAACCGCCGGTGAACCGGCA
TCGTCCGTCCGTGGATGTGCTGTTCCGTTCGGCCGCGCAGCATGCGGGCAAGAACGCGGTTGGGGTGATCCTGACCGGGA
TGGGGCGCGACGGCGCCGCCGGATTGCTGGACATGAAGAAAGCAGGGGCATACACCCTTGCGCAGGACGAAGCGAGCTGT
ATCGTGTTCGGCATGCCGCGTGAAGCGATTGCGCTCGGCGCGGCCGACGAGATCGCATCGTTGCCGGAAATGAGCCGGCG
CGTGATGGCGCGTCTGTCGTCGATGGGCGATCGCGTTCAGCGGGTATGA

Upstream 100 bases:

>100_bases
CGACGCCCGCCGCCGCCCGCCCGAAGGTCGAGCTGTTCGGCGCCGGCTCGCGCCCGATTAATTCAAACAACGCCAGAACT
ACAGAGGAGGCGTGAGCGCT

Downstream 100 bases:

>100_bases
TGCGCGCCAGCAGGATTTGAGGCGCCGGTTTCAGACGGTCGGGCGCCGCACCGTGGATAAAGCAAAGGGAATGAAATGGA
TAAGGGAATGAAGATTCTGG

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MQKIKVLCVDDSALIRSLMTEIINGQPDMTVVATAPDPLVARELIKQHNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVV
MVSSLTERGNEITLRALELGAVDFVTKPKVGIRDGMLDYSEKLADKIRAAARARVRQSAPVQHAAAHAAHAPVGAAPLFN
NPLLSTEKLIIVGASTGGTEAIREVLVPLPPDAPAVLIAQHMPPGFTKSFAQRLNGLCRITVKEAEHGERVLPGHAYIAP
GHAHLLLARSGANYIAHLSDEPPVNRHRPSVDVLFRSAAQHAGKNAVGVILTGMGRDGAAGLLDMKKAGAYTLAQDEASC
IVFGMPREAIALGAADEIASLPEMSRRVMARLSSMGDRVQRV

Sequences:

>Translated_362_residues
MQKIKVLCVDDSALIRSLMTEIINGQPDMTVVATAPDPLVARELIKQHNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVV
MVSSLTERGNEITLRALELGAVDFVTKPKVGIRDGMLDYSEKLADKIRAAARARVRQSAPVQHAAAHAAHAPVGAAPLFN
NPLLSTEKLIIVGASTGGTEAIREVLVPLPPDAPAVLIAQHMPPGFTKSFAQRLNGLCRITVKEAEHGERVLPGHAYIAP
GHAHLLLARSGANYIAHLSDEPPVNRHRPSVDVLFRSAAQHAGKNAVGVILTGMGRDGAAGLLDMKKAGAYTLAQDEASC
IVFGMPREAIALGAADEIASLPEMSRRVMARLSSMGDRVQRV
>Mature_362_residues
MQKIKVLCVDDSALIRSLMTEIINGQPDMTVVATAPDPLVARELIKQHNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVV
MVSSLTERGNEITLRALELGAVDFVTKPKVGIRDGMLDYSEKLADKIRAAARARVRQSAPVQHAAAHAAHAPVGAAPLFN
NPLLSTEKLIIVGASTGGTEAIREVLVPLPPDAPAVLIAQHMPPGFTKSFAQRLNGLCRITVKEAEHGERVLPGHAYIAP
GHAHLLLARSGANYIAHLSDEPPVNRHRPSVDVLFRSAAQHAGKNAVGVILTGMGRDGAAGLLDMKKAGAYTLAQDEASC
IVFGMPREAIALGAADEIASLPEMSRRVMARLSSMGDRVQRV

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788192, Length=355, Percent_Identity=68.4507042253521, Blast_Score=489, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEB_BURXL (Q13SY2)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_560859.1
- ProteinModelPortal:   Q13SY2
- SMR:   Q13SY2
- GeneID:   4006303
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A0124
- HOGENOM:   HBG705324
- OMA:   FVTKPKL
- ProtClustDB:   PRK00742
- GO:   GO:0005737
- GO:   GO:0006935
- HAMAP:   MF_00099
- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789
- Gene3D:   G3DSA:3.40.50.180
- PIRSF:   PIRSF000876
- SMART:   SM00448

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg; SSF52738 Chemotax_RR_pGlu_Me-esterase; SSF52172 CheY_like

EC number: =3.1.1.61

Molecular weight: Translated: 38844; Mature: 38844

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50122 CHEB; PS50110 RESPONSE_REGULATORY

Important sites: ACT_SITE 175-175 ACT_SITE 201-201 ACT_SITE 297-297

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIKVLCVDDSALIRSLMTEIINGQPDMTVVATAPDPLVARELIKQHNPDVLTLDVEMP
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCC
RMDGLDFLEKLMRLRPMPVVMVSSLTERGNEITLRALELGAVDFVTKPKVGIRDGMLDYS
CCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEEEECCEEEECCCCCCCCCCHHHHH
EKLADKIRAAARARVRQSAPVQHAAAHAAHAPVGAAPLFNNPLLSTEKLIIVGASTGGTE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCHH
AIREVLVPLPPDAPAVLIAQHMPPGFTKSFAQRLNGLCRITVKEAEHGERVLPGHAYIAP
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEECCCCCCEECCCCEEECC
GHAHLLLARSGANYIAHLSDEPPVNRHRPSVDVLFRSAAQHAGKNAVGVILTGMGRDGAA
CCEEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCC
GLLDMKKAGAYTLAQDEASCIVFGMPREAIALGAADEIASLPEMSRRVMARLSSMGDRVQ
CHHHHHHCCCEEEECCCCCEEEEECCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
RV
CC
>Mature Secondary Structure
MQKIKVLCVDDSALIRSLMTEIINGQPDMTVVATAPDPLVARELIKQHNPDVLTLDVEMP
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCC
RMDGLDFLEKLMRLRPMPVVMVSSLTERGNEITLRALELGAVDFVTKPKVGIRDGMLDYS
CCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEEEECCEEEECCCCCCCCCCHHHHH
EKLADKIRAAARARVRQSAPVQHAAAHAAHAPVGAAPLFNNPLLSTEKLIIVGASTGGTE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCHH
AIREVLVPLPPDAPAVLIAQHMPPGFTKSFAQRLNGLCRITVKEAEHGERVLPGHAYIAP
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEECCCCCCEECCCCEEECC
GHAHLLLARSGANYIAHLSDEPPVNRHRPSVDVLFRSAAQHAGKNAVGVILTGMGRDGAA
CCEEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCC
GLLDMKKAGAYTLAQDEASCIVFGMPREAIALGAADEIASLPEMSRRVMARLSSMGDRVQ
CHHHHHHCCCEEEECCCCCEEEEECCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
RV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA