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The map label for this gene is slt [H]

Identifier: 91785579

GI number: 91785579

Start: 4634624

End: 4636591

Strand: Reverse

Name: slt [H]

Synonym: Bxe_A0198

Alternate gene names: 91785579

Gene position: 4636591-4634624 (Counterclockwise)

Preceding gene: 91785581

Following gene: 91785578

Centisome position: 94.7

GC content: 64.23

Gene sequence:

>1968_bases
ATGTCAAAACGCCTTTACCGAGTATATCGCGCGGCCGGTCTGGCGCTTGCCGCCGCGGCGCTCGTCGCGTGCAGCACGGC
CTCCGCCGTCAAGCCCCTTCCTCTTTCGCAACTCACGAACGACGACCAGATCTTCGTTCAACTGCGCGAGGCCGCCCGCA
GTAACGACGCGGCGCGCGCCGCGCAGTTGGCCAGCATGATCCCGAGCTATCCGGCGCCTTCGTATCTGGAGTACTTCCAG
ATCAAGCCGCAACTGTTCGATTCCGGCGGGCACGCGCGGGTCGACGCGCCGGACGCACCGGTGCTGAGCTTCCTGCAGAA
GTACGACGGCCAGGCGATCGCCGACCGCCTGCGCAACGACTACCTCACGGTGCTCGGCGCTCGTCATGACTGGCGCAATT
TCGATCAGCAATACGCCCGTTTCGTGCTGAACGACGACACGCAGGTGAAGTGCTACGCGCTCGAATCGCGCGCCTCGCGC
GGCGAGAACGTGGCCGACGCGGCTCGCGCGCTGCTCGTCGATCCGAAATGGTACGGCGACGGCTGCGTGGATCTGATCAA
CGCGCTCGCCATCAACCAGCAGTTCAGCTCCGCCGACGTGTGGCAACAGATCCGCCTCGCCTACGAACAGAACTACACCA
ACACGGGCGCGAAGCTCGTCGACGCGCTCAGCAACCAGCCGCCCGACCCGGTGCTGTTCAATCAGGCCACCACCACGCCG
CCGTTGCTGCTCGCGCGTGGCGTCGGACCGGATACGCAGTCGCATCAACTCGCGTTGCTGGCCATCACGCGCATGGCGCG
CAACGACCCGGCTATGGCCGCGGCCACGTTCGCCTCGGTGGCGCCGTCGCTGAGTTCGCCGGAGCGCGCCATCGGCTGGG
GCACGATTGCGTATCAGGCAGCGGCCAGGCAGATGCCGGGCGCGGTGGACTGGTATCGCCTGTCGGTGAACGCGCCGCTG
TCGAATCCCGCGTATGAATGGCGCACCCGCACCGCCTTGCTCGCGGGCGACTGGACGATGGTGCGCTGGTCGATCGAACA
GATGCCGGCGGCGCTGCGCAATCAGCCGTCGTGGGTGTATTGGCACGCTCGCGCGCTCAAGCAGGCCGGCGAAACGACCA
CCGCCACCCAGGAATTCGAATCGATTTCGCGGGGCTACAACTTCTACGGCCAACTGGCCGCGGAAGAACTGGGCCAGAAG
ATCACGGTCCCGCCGAAAACCACGGTGAGCGACGCCGAAGTGCAACAGGCCGGCAATACGCCCGGCTTCGATCTGGCGCA
GCGCTTCTATGCGCTGAATCTGCGGCTCGAAGGCAATCGCGAATGGAACTGGCCGCTGCGCAACATGAGCGACCGGCAAC
TGCTCGCCGCCGCCGAATACGCACGCCGTATCCAGCTGTATGACCGCACTGTCAACACGGCGGATCGCACGAAGACCGAG
CACGATTTCTCGCTGCGTTATCTGTCGCCGTTCAAGGATATCGTCGAGCGCGATTCGCAGTCGAACGGGCTCGACGTGGA
ATGGGCCTATGGCCTGATTCGCCAGGAGTCGCGCTTCATCATGAATGCGCGCTCCGAGGTCGGCGCGAGCGGTTTGATGC
AGTTGATGCCGGGCACCGCGCAACTGGTCGCCAAGAAAATCGGCCTGGGTCCAATCTCGCGCGAACAGATGAACGACATC
AACACCAACATCCTGCTCGGCACGAACTATCTGTCGATGATCTACAATCAGTTCGACGGGTCCGCCGTGCTGGCCACCGC
GGGCTATAACGCAGGGCCCGGCCGTCCGCGCAGCTGGCGGCAATCCTTGCAGCGTCCGGTGGAAGGCGCGATCTTCGCCG
AGGCGATTCCGTTCCAGGAAACGCGCGACTACGTTAAGAATGTGTTGTCCAACACGGTCTATTACGCGGCATTGTTCGAA
GGCCGTCCGCAATCGCTGAAGGCGCGTCTGGGTTACATCGCACCGTAA

Upstream 100 bases:

>100_bases
TGCAGCCTTGCTTCCAATAGCATTTTACGCAGCGCCTTTTTCGATTCCGCGGCAGGGTTGCATGCTATGCTTGGGTTCAA
TTCGCGCTCCAGAAACAACG

Downstream 100 bases:

>100_bases
GCGCGCCGTGCCGCCGCCGTCCCGTTCCGGGCGGCGGCGCGCCACGCCAGCCGTTGCCGCGGCTTCCACCAGGGAGTCGA
AAATGCGACACAAAGCCATT

Product: transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: Exomuramidase; Peptidoglycan lytic exotransglycosylase; Slt70 [H]

Number of amino acids: Translated: 655; Mature: 654

Protein sequence:

>655_residues
MSKRLYRVYRAAGLALAAAALVACSTASAVKPLPLSQLTNDDQIFVQLREAARSNDAARAAQLASMIPSYPAPSYLEYFQ
IKPQLFDSGGHARVDAPDAPVLSFLQKYDGQAIADRLRNDYLTVLGARHDWRNFDQQYARFVLNDDTQVKCYALESRASR
GENVADAARALLVDPKWYGDGCVDLINALAINQQFSSADVWQQIRLAYEQNYTNTGAKLVDALSNQPPDPVLFNQATTTP
PLLLARGVGPDTQSHQLALLAITRMARNDPAMAAATFASVAPSLSSPERAIGWGTIAYQAAARQMPGAVDWYRLSVNAPL
SNPAYEWRTRTALLAGDWTMVRWSIEQMPAALRNQPSWVYWHARALKQAGETTTATQEFESISRGYNFYGQLAAEELGQK
ITVPPKTTVSDAEVQQAGNTPGFDLAQRFYALNLRLEGNREWNWPLRNMSDRQLLAAAEYARRIQLYDRTVNTADRTKTE
HDFSLRYLSPFKDIVERDSQSNGLDVEWAYGLIRQESRFIMNARSEVGASGLMQLMPGTAQLVAKKIGLGPISREQMNDI
NTNILLGTNYLSMIYNQFDGSAVLATAGYNAGPGRPRSWRQSLQRPVEGAIFAEAIPFQETRDYVKNVLSNTVYYAALFE
GRPQSLKARLGYIAP

Sequences:

>Translated_655_residues
MSKRLYRVYRAAGLALAAAALVACSTASAVKPLPLSQLTNDDQIFVQLREAARSNDAARAAQLASMIPSYPAPSYLEYFQ
IKPQLFDSGGHARVDAPDAPVLSFLQKYDGQAIADRLRNDYLTVLGARHDWRNFDQQYARFVLNDDTQVKCYALESRASR
GENVADAARALLVDPKWYGDGCVDLINALAINQQFSSADVWQQIRLAYEQNYTNTGAKLVDALSNQPPDPVLFNQATTTP
PLLLARGVGPDTQSHQLALLAITRMARNDPAMAAATFASVAPSLSSPERAIGWGTIAYQAAARQMPGAVDWYRLSVNAPL
SNPAYEWRTRTALLAGDWTMVRWSIEQMPAALRNQPSWVYWHARALKQAGETTTATQEFESISRGYNFYGQLAAEELGQK
ITVPPKTTVSDAEVQQAGNTPGFDLAQRFYALNLRLEGNREWNWPLRNMSDRQLLAAAEYARRIQLYDRTVNTADRTKTE
HDFSLRYLSPFKDIVERDSQSNGLDVEWAYGLIRQESRFIMNARSEVGASGLMQLMPGTAQLVAKKIGLGPISREQMNDI
NTNILLGTNYLSMIYNQFDGSAVLATAGYNAGPGRPRSWRQSLQRPVEGAIFAEAIPFQETRDYVKNVLSNTVYYAALFE
GRPQSLKARLGYIAP
>Mature_654_residues
SKRLYRVYRAAGLALAAAALVACSTASAVKPLPLSQLTNDDQIFVQLREAARSNDAARAAQLASMIPSYPAPSYLEYFQI
KPQLFDSGGHARVDAPDAPVLSFLQKYDGQAIADRLRNDYLTVLGARHDWRNFDQQYARFVLNDDTQVKCYALESRASRG
ENVADAARALLVDPKWYGDGCVDLINALAINQQFSSADVWQQIRLAYEQNYTNTGAKLVDALSNQPPDPVLFNQATTTPP
LLLARGVGPDTQSHQLALLAITRMARNDPAMAAATFASVAPSLSSPERAIGWGTIAYQAAARQMPGAVDWYRLSVNAPLS
NPAYEWRTRTALLAGDWTMVRWSIEQMPAALRNQPSWVYWHARALKQAGETTTATQEFESISRGYNFYGQLAAEELGQKI
TVPPKTTVSDAEVQQAGNTPGFDLAQRFYALNLRLEGNREWNWPLRNMSDRQLLAAAEYARRIQLYDRTVNTADRTKTEH
DFSLRYLSPFKDIVERDSQSNGLDVEWAYGLIRQESRFIMNARSEVGASGLMQLMPGTAQLVAKKIGLGPISREQMNDIN
TNILLGTNYLSMIYNQFDGSAVLATAGYNAGPGRPRSWRQSLQRPVEGAIFAEAIPFQETRDYVKNVLSNTVYYAALFEG
RPQSLKARLGYIAP

Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasm. Note=Tightly associated with the murein sacculus (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=649, Percent_Identity=26.502311248074, Blast_Score=178, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016026
- InterPro:   IPR008258
- InterPro:   IPR012289
- InterPro:   IPR008939
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 72768; Mature: 72637

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRLYRVYRAAGLALAAAALVACSTASAVKPLPLSQLTNDDQIFVQLREAARSNDAARA
CCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHCCCCHHHHHHHHHHHCCCHHHHH
AQLASMIPSYPAPSYLEYFQIKPQLFDSGGHARVDAPDAPVLSFLQKYDGQAIADRLRND
HHHHHHCCCCCCCCHHHHHCCCHHHCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHCCC
YLTVLGARHDWRNFDQQYARFVLNDDTQVKCYALESRASRGENVADAARALLVDPKWYGD
CEEEEECCCHHHHHHHHHHHHEECCCCEEEEEEECCHHCCCCCHHHHHHHHEECCCCCCC
GCVDLINALAINQQFSSADVWQQIRLAYEQNYTNTGAKLVDALSNQPPDPVLFNQATTTP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEECCCCCCC
PLLLARGVGPDTQSHQLALLAITRMARNDPAMAAATFASVAPSLSSPERAIGWGTIAYQA
CCEEECCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHH
AARQMPGAVDWYRLSVNAPLSNPAYEWRTRTALLAGDWTMVRWSIEQMPAALRNQPSWVY
HHHHCCCCCEEEEEEECCCCCCCCHHHHHCEEEEECCCEEEEEEHHHHHHHHCCCCCEEE
WHARALKQAGETTTATQEFESISRGYNFYGQLAAEELGQKITVPPKTTVSDAEVQQAGNT
EHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCCC
PGFDLAQRFYALNLRLEGNREWNWPLRNMSDRQLLAAAEYARRIQLYDRTVNTADRTKTE
CCHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCC
HDFSLRYLSPFKDIVERDSQSNGLDVEWAYGLIRQESRFIMNARSEVGASGLMQLMPGTA
CCCEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHH
QLVAKKIGLGPISREQMNDINTNILLGTNYLSMIYNQFDGSAVLATAGYNAGPGRPRSWR
HHHHHHHCCCCCCHHHHHCCCCEEEECCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHH
QSLQRPVEGAIFAEAIPFQETRDYVKNVLSNTVYYAALFEGRPQSLKARLGYIAP
HHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHCCCCCC
>Mature Secondary Structure 
SKRLYRVYRAAGLALAAAALVACSTASAVKPLPLSQLTNDDQIFVQLREAARSNDAARA
CHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHCCCCHHHHHHHHHHHCCCHHHHH
AQLASMIPSYPAPSYLEYFQIKPQLFDSGGHARVDAPDAPVLSFLQKYDGQAIADRLRND
HHHHHHCCCCCCCCHHHHHCCCHHHCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHCCC
YLTVLGARHDWRNFDQQYARFVLNDDTQVKCYALESRASRGENVADAARALLVDPKWYGD
CEEEEECCCHHHHHHHHHHHHEECCCCEEEEEEECCHHCCCCCHHHHHHHHEECCCCCCC
GCVDLINALAINQQFSSADVWQQIRLAYEQNYTNTGAKLVDALSNQPPDPVLFNQATTTP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEECCCCCCC
PLLLARGVGPDTQSHQLALLAITRMARNDPAMAAATFASVAPSLSSPERAIGWGTIAYQA
CCEEECCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHH
AARQMPGAVDWYRLSVNAPLSNPAYEWRTRTALLAGDWTMVRWSIEQMPAALRNQPSWVY
HHHHCCCCCEEEEEEECCCCCCCCHHHHHCEEEEECCCEEEEEEHHHHHHHHCCCCCEEE
WHARALKQAGETTTATQEFESISRGYNFYGQLAAEELGQKITVPPKTTVSDAEVQQAGNT
EHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCCC
PGFDLAQRFYALNLRLEGNREWNWPLRNMSDRQLLAAAEYARRIQLYDRTVNTADRTKTE
CCHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCC
HDFSLRYLSPFKDIVERDSQSNGLDVEWAYGLIRQESRFIMNARSEVGASGLMQLMPGTA
CCCEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHH
QLVAKKIGLGPISREQMNDINTNILLGTNYLSMIYNQFDGSAVLATAGYNAGPGRPRSWR
HHHHHHHCCCCCCHHHHHCCCCEEEECCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHH
QSLQRPVEGAIFAEAIPFQETRDYVKNVLSNTVYYAALFEGRPQSLKARLGYIAP
HHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]