| Definition | Burkholderia xenovorans LB400 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007951 |
| Length | 4,895,836 |
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The map label for this gene is thiE [H]
Identifier: 91785393
GI number: 91785393
Start: 4448544
End: 4449647
Strand: Reverse
Name: thiE [H]
Synonym: Bxe_A0386
Alternate gene names: 91785393
Gene position: 4449647-4448544 (Counterclockwise)
Preceding gene: 91785394
Following gene: 91785392
Centisome position: 90.89
GC content: 67.84
Gene sequence:
>1104_bases ATGACGCAGACTTTGACATTGAAAGATCGCGACCTCTTCTGGCCGCCCGCCGACGAACTCACAGAGGCCGCCGAGCGCAT CCGCGCCCGGCTGGGCGACTGGCCGCCGACGCACGCGCCGTGGCGCATCTGCCTGACCGCGCCGGACGAACTGAACGGCA GCGACCTGATCGTGATTGCCGACGCGCAGCAGCACGGCGAGCAGATGGCGCACTGGCTGGTGCGCGGCGCCGGCGTGATC GAAGCCGCCGAGGAGAAGGCCACGCTGCATCTGGGCGGCGAAAAATACCGCCTGGAAGGCCATCTGGCGGAAGACTGGAT TGCCGCGCTGGCGGCCTTCCTGGATTGTGGCTTCGATCCGCATGACGCGTTGGTGCTGGCGCTGGCCTGGCGCGACGGCG ACGAAACCAGTGCCGACGACGCCTTTCCCACCGATCTCAGCCGCTTTCCGCGTCTTGCCGGTTTGCCCGACGCGCCTGCG CAGGCGTTCGCGCGCTGCCCGGAGCGGCTCGGCCTGTATCCCGTGCTGCCGACCGCGGAATGGGTCGAGCGGGTAGTCGG TTTCGGCGTGAAGACGGTGCAGTTGCGCCGCAAATCCGCCGAACCCGCCGACGAACTGAAGCGCGAAATTGCCCGCTGCG TGGCGGTCGGCCGTCAGTACGATGCGCAGGTGTTCATCAACGACCATTGGCAGGCCGCGCTCGAAGCCGGCGCTTACGGC GTCCACCTCGGCCAGGAAGACGTGCATACGGCGGACCTCGCCGCGCTCGCGTCGGCAGGCGTGCGGCTCGGTCTGTCGAC CCACGGTTTCTACGAGATTCTGAAAGCGCTGCATTTCCGGCCGAGCTACATTGCACTGGGCGCGGTGTTTCCGACCACCA CCAAGATCATGCCGACCGAGCCGCAAGGCCTGCGGCGTTTGGCCCGCTACGTGCGGTTGCTCGATGGCGTCGTGCCGCTG GTGGCGATCGGCGGCATCGACCTGCAAGTGCTGCCCGACGTGCTGGCCACGGGCGTGGGCAGCGCGGCCGTGGTGCGCGC GGTGACCGAAGCGGCGGACCCGGCCTCTGCCGTTTCTGCACTGCAACACGCGTTTACGCAATAA
Upstream 100 bases:
>100_bases GCCAGGCTTTTCTGGCGGGGCCGATGGCCGAGCGCGAAAGCGCGCACGCGAGCACGCCGGTGGTCGGCATGCCGTTCTGG CATCAAGACGGGAGCGCCGC
Downstream 100 bases:
>100_bases TCGTCACGTTTGGTTAAGGACGGGGCACCCTCAGGGCAACTTTTGCACGATGGCCCTATAATTCGGCCTTCCGTGTAAAA GGACTGTCAGTTTCGTGTCT
Product: putative thiamin-phosphate pyrophosphorylase, ThiE
Products: NA
Alternate protein names: TMP pyrophosphorylase; TMP-PPase; Thiamine-phosphate synthase [H]
Number of amino acids: Translated: 367; Mature: 366
Protein sequence:
>367_residues MTQTLTLKDRDLFWPPADELTEAAERIRARLGDWPPTHAPWRICLTAPDELNGSDLIVIADAQQHGEQMAHWLVRGAGVI EAAEEKATLHLGGEKYRLEGHLAEDWIAALAAFLDCGFDPHDALVLALAWRDGDETSADDAFPTDLSRFPRLAGLPDAPA QAFARCPERLGLYPVLPTAEWVERVVGFGVKTVQLRRKSAEPADELKREIARCVAVGRQYDAQVFINDHWQAALEAGAYG VHLGQEDVHTADLAALASAGVRLGLSTHGFYEILKALHFRPSYIALGAVFPTTTKIMPTEPQGLRRLARYVRLLDGVVPL VAIGGIDLQVLPDVLATGVGSAAVVRAVTEAADPASAVSALQHAFTQ
Sequences:
>Translated_367_residues MTQTLTLKDRDLFWPPADELTEAAERIRARLGDWPPTHAPWRICLTAPDELNGSDLIVIADAQQHGEQMAHWLVRGAGVI EAAEEKATLHLGGEKYRLEGHLAEDWIAALAAFLDCGFDPHDALVLALAWRDGDETSADDAFPTDLSRFPRLAGLPDAPA QAFARCPERLGLYPVLPTAEWVERVVGFGVKTVQLRRKSAEPADELKREIARCVAVGRQYDAQVFINDHWQAALEAGAYG VHLGQEDVHTADLAALASAGVRLGLSTHGFYEILKALHFRPSYIALGAVFPTTTKIMPTEPQGLRRLARYVRLLDGVVPL VAIGGIDLQVLPDVLATGVGSAAVVRAVTEAADPASAVSALQHAFTQ >Mature_366_residues TQTLTLKDRDLFWPPADELTEAAERIRARLGDWPPTHAPWRICLTAPDELNGSDLIVIADAQQHGEQMAHWLVRGAGVIE AAEEKATLHLGGEKYRLEGHLAEDWIAALAAFLDCGFDPHDALVLALAWRDGDETSADDAFPTDLSRFPRLAGLPDAPAQ AFARCPERLGLYPVLPTAEWVERVVGFGVKTVQLRRKSAEPADELKREIARCVAVGRQYDAQVFINDHWQAALEAGAYGV HLGQEDVHTADLAALASAGVRLGLSTHGFYEILKALHFRPSYIALGAVFPTTTKIMPTEPQGLRRLARYVRLLDGVVPLV AIGGIDLQVLPDVLATGVGSAAVVRAVTEAADPASAVSALQHAFTQ
Specific function: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) [H]
COG id: COG0352
COG function: function code H; Thiamine monophosphate synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the TMP-PPase family [H]
Homologues:
Organism=Escherichia coli, GI1790426, Length=192, Percent_Identity=55.2083333333333, Blast_Score=196, Evalue=3e-51,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013785 - InterPro: IPR022998 - InterPro: IPR003733 [H]
Pfam domain/function: PF02581 TMP-TENI [H]
EC number: =2.5.1.3 [H]
Molecular weight: Translated: 39758; Mature: 39626
Theoretical pI: Translated: 5.02; Mature: 5.02
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 0.5 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTQTLTLKDRDLFWPPADELTEAAERIRARLGDWPPTHAPWRICLTAPDELNGSDLIVIA CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEE DAQQHGEQMAHWLVRGAGVIEAAEEKATLHLGGEKYRLEGHLAEDWIAALAAFLDCGFDP CCHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHCCCCC HDALVLALAWRDGDETSADDAFPTDLSRFPRLAGLPDAPAQAFARCPERLGLYPVLPTAE CCCEEEEEEECCCCCCCCCCCCCCCHHHCCHHCCCCCCHHHHHHHCHHHCCCEECCCCHH WVERVVGFGVKTVQLRRKSAEPADELKREIARCVAVGRQYDAQVFINDHWQAALEAGAYG HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCE VHLGQEDVHTADLAALASAGVRLGLSTHGFYEILKALHFRPSYIALGAVFPTTTKIMPTE EECCCCHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC PQGLRRLARYVRLLDGVVPLVAIGGIDLQVLPDVLATGVGSAAVVRAVTEAADPASAVSA CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHH LQHAFTQ HHHHHCC >Mature Secondary Structure TQTLTLKDRDLFWPPADELTEAAERIRARLGDWPPTHAPWRICLTAPDELNGSDLIVIA CCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEE DAQQHGEQMAHWLVRGAGVIEAAEEKATLHLGGEKYRLEGHLAEDWIAALAAFLDCGFDP CCHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHCCCCC HDALVLALAWRDGDETSADDAFPTDLSRFPRLAGLPDAPAQAFARCPERLGLYPVLPTAE CCCEEEEEEECCCCCCCCCCCCCCCHHHCCHHCCCCCCHHHHHHHCHHHCCCEECCCCHH WVERVVGFGVKTVQLRRKSAEPADELKREIARCVAVGRQYDAQVFINDHWQAALEAGAYG HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCE VHLGQEDVHTADLAALASAGVRLGLSTHGFYEILKALHFRPSYIALGAVFPTTTKIMPTE EECCCCHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC PQGLRRLARYVRLLDGVVPLVAIGGIDLQVLPDVLATGVGSAAVVRAVTEAADPASAVSA CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHH LQHAFTQ HHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA