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The map label for this gene is mlaA [H]

Identifier: 91785389

GI number: 91785389

Start: 4445173

End: 4446216

Strand: Reverse

Name: mlaA [H]

Synonym: Bxe_A0390

Alternate gene names: 91785389

Gene position: 4446216-4445173 (Counterclockwise)

Preceding gene: 91785390

Following gene: 91785388

Centisome position: 90.82

GC content: 65.9

Gene sequence:

>1044_bases
ATGCAGACCACACGCATCCGGGCCGCGCATGCCTTCCCGATCGCTAAACTGGCAGTCGTCACAGCGCTGCTCGCCGGCTG
TACCACCGTGCAGACACCGACCAAGGGCGACCCGCTCGAAGGTCTGAACCGCACGATGTTCACCGTCAACGACAAGCTCG
ACCAGTACGCGCTCAAGCCGGTCGCGAAGGGCTATGTCTGGGCGACCCCGCAGCCGGTGCGCGACAGCGTGACGAACTTC
TTTTCGAATATCGGCGACGTCTACATTGCGGCCAACAACCTGCTGCAGTTGAAGATCACCGACGGTGTCGAAGACATCAT
GCGGATCGTGATCAATACGGTGTTCGGCGTGGGCGGCCTGTTCGACGTGGCGACGCTTGCCCGGCTGCCCAAGCACGACA
ACGACCTCGGCCTGACGCTCGGCCACTACGGCGTGCCGGCGGGCCCGTACCTCGTGCTGCCGCTGTTCGGGCCGAGCACC
GTGCGCGACGCGGTCGGCTCGATCGGCAATTACTATATCAACCCGCTCAGCTACGTCGATCCGGCGGGTCTGAGCTGGGC
GCTGTACGGCCTGAATGTGGTCAACACGCGCGCCAATCTGCTGGGCGCGAGCGACGTGCTGGAAGGCGCCGCGCTCGACA
AATACTCGTTCGTGCGCAATGCGTATCTGCAACGTCGTCAGTACCTGTTGTCGGACGGCAGGCAGTCGCAGGCGCTGCCG
AACTACGGCGACGAAGCGCCGCTGCCGAAATACGACGATGTGGACGGCAGCGCGGCCGGTGCGCCGGCAGGCGCTGTAAC
CGGAACGGCGGGTGCGGCAGGCACGCAGGGTGCTGCTGCAGCCAGGGCGGCGCCTGCTTCCGGCGCGACAGCGGCAACGC
CACCGCAAGCGGCCTCGGGCACTGCGGCAGCGCCGGAAGCCGCGTCCGGCAGCGCCGAAACGCCGCCGCTCGACCTGAAC
GGCGGCCCTGAAACGACGCAGATTCCGGCCGGTCAGCTGGTTCCGCCTACGCGTTTCAATTTTCCGTCGTTCAAATTGCG
TTGA

Upstream 100 bases:

>100_bases
GTGCGTCCAAGCCTGGCGCGGCCGGCAGCGCACCCGCAGCAGCGCCTGCGGCACCGGGCCTGCCCGCCTCCGGCGCGGGC
GCTCAATAAGGAGAAAAAGA

Downstream 100 bases:

>100_bases
TCGTGCAGCCGTAACAGATCGATACGACTCTCGCAGTTTGCGCATGGATTGCGGCTGAACTCGCGTGCTAATGTCGGCTC
AAACGGCTGCACCATTTTTA

Product: putative transmembrane lipoprotein, VacJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MQTTRIRAAHAFPIAKLAVVTALLAGCTTVQTPTKGDPLEGLNRTMFTVNDKLDQYALKPVAKGYVWATPQPVRDSVTNF
FSNIGDVYIAANNLLQLKITDGVEDIMRIVINTVFGVGGLFDVATLARLPKHDNDLGLTLGHYGVPAGPYLVLPLFGPST
VRDAVGSIGNYYINPLSYVDPAGLSWALYGLNVVNTRANLLGASDVLEGAALDKYSFVRNAYLQRRQYLLSDGRQSQALP
NYGDEAPLPKYDDVDGSAAGAPAGAVTGTAGAAGTQGAAAARAAPASGATAATPPQAASGTAAAPEAASGSAETPPLDLN
GGPETTQIPAGQLVPPTRFNFPSFKLR

Sequences:

>Translated_347_residues
MQTTRIRAAHAFPIAKLAVVTALLAGCTTVQTPTKGDPLEGLNRTMFTVNDKLDQYALKPVAKGYVWATPQPVRDSVTNF
FSNIGDVYIAANNLLQLKITDGVEDIMRIVINTVFGVGGLFDVATLARLPKHDNDLGLTLGHYGVPAGPYLVLPLFGPST
VRDAVGSIGNYYINPLSYVDPAGLSWALYGLNVVNTRANLLGASDVLEGAALDKYSFVRNAYLQRRQYLLSDGRQSQALP
NYGDEAPLPKYDDVDGSAAGAPAGAVTGTAGAAGTQGAAAARAAPASGATAATPPQAASGTAAAPEAASGSAETPPLDLN
GGPETTQIPAGQLVPPTRFNFPSFKLR
>Mature_347_residues
MQTTRIRAAHAFPIAKLAVVTALLAGCTTVQTPTKGDPLEGLNRTMFTVNDKLDQYALKPVAKGYVWATPQPVRDSVTNF
FSNIGDVYIAANNLLQLKITDGVEDIMRIVINTVFGVGGLFDVATLARLPKHDNDLGLTLGHYGVPAGPYLVLPLFGPST
VRDAVGSIGNYYINPLSYVDPAGLSWALYGLNVVNTRANLLGASDVLEGAALDKYSFVRNAYLQRRQYLLSDGRQSQALP
NYGDEAPLPKYDDVDGSAAGAPAGAVTGTAGAAGTQGAAAARAAPASGATAATPPQAASGTAAAPEAASGSAETPPLDLN
GGPETTQIPAGQLVPPTRFNFPSFKLR

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=239, Percent_Identity=36.8200836820084, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 36069; Mature: 36069

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTTRIRAAHAFPIAKLAVVTALLAGCTTVQTPTKGDPLEGLNRTMFTVNDKLDQYALKP
CCCCEEEHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCEEEEECHHHHHHHHHH
VAKGYVWATPQPVRDSVTNFFSNIGDVYIAANNLLQLKITDGVEDIMRIVINTVFGVGGL
HHCCEEECCCCHHHHHHHHHHHHCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHCCHH
FDVATLARLPKHDNDLGLTLGHYGVPAGPYLVLPLFGPSTVRDAVGSIGNYYINPLSYVD
HHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHEEECCCCCCC
PAGLSWALYGLNVVNTRANLLGASDVLEGAALDKYSFVRNAYLQRRQYLLSDGRQSQALP
CCCCEEEEECCCCCHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NYGDEAPLPKYDDVDGSAAGAPAGAVTGTAGAAGTQGAAAARAAPASGATAATPPQAASG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCC
TAAAPEAASGSAETPPLDLNGGPETTQIPAGQLVPPTRFNFPSFKLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTTRIRAAHAFPIAKLAVVTALLAGCTTVQTPTKGDPLEGLNRTMFTVNDKLDQYALKP
CCCCEEEHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCEEEEECHHHHHHHHHH
VAKGYVWATPQPVRDSVTNFFSNIGDVYIAANNLLQLKITDGVEDIMRIVINTVFGVGGL
HHCCEEECCCCHHHHHHHHHHHHCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHCCHH
FDVATLARLPKHDNDLGLTLGHYGVPAGPYLVLPLFGPSTVRDAVGSIGNYYINPLSYVD
HHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHEEECCCCCCC
PAGLSWALYGLNVVNTRANLLGASDVLEGAALDKYSFVRNAYLQRRQYLLSDGRQSQALP
CCCCEEEEECCCCCHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NYGDEAPLPKYDDVDGSAAGAPAGAVTGTAGAAGTQGAAAARAAPASGATAATPPQAASG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCC
TAAAPEAASGSAETPPLDLNGGPETTQIPAGQLVPPTRFNFPSFKLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]