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The map label for this gene is hitA [H]

Identifier: 91785371

GI number: 91785371

Start: 4431551

End: 4431916

Strand: Reverse

Name: hitA [H]

Synonym: Bxe_A0408

Alternate gene names: 91785371

Gene position: 4431916-4431551 (Counterclockwise)

Preceding gene: 91785372

Following gene: 91785370

Centisome position: 90.52

GC content: 63.39

Gene sequence:

>366_bases
ATGAGTCACGACCCGAACTGCCTTTTCTGCAAGATCGCCGCCGGCGCGATTCCGTCGACCAAAGTCCACGAAGACGACGA
GTTCGTTGCCTTCCGCGACATCCGCCCGGCCGCCGAAACCCACGTGCTGGTGATCCCGCGCAGGCACATCGCCACGCTGT
CGAATTGCACCGGAAGCGATGCACCGCTGCTTGGTAGAATGCTTGTCCTGACCGCGCGTCTGGCGGATCAGTTAGGCGTG
GCGTACACGGGCGGCGAAACGGGTTTTCGCACGGTAATCAATACCGGTCCGGGCGGCGGGCAGGAGGTGTATCACCTGCA
CGCTCATATTCTCGCGGGACCGCGCCCCTGGCAGCGCATGGGTTGA

Upstream 100 bases:

>100_bases
TCCGCGCGGCTGGTTCTGAGTTTCGTCCGGGCGTTGCCGGGCCTGACATGAACCGCGCCGCGCACGTTTCGCGCTCCAGC
CATACTGTGTCAGGAATACG

Downstream 100 bases:

>100_bases
CAGGGCAACCGGGCGGCGCGGTGAGTTTTGGTCACGGACAATAGCGCGGCCGATGTTTTTGCCGCATTGTAATGTCGCCG
ACGCGATCGTCTGGCCACAA

Product: putative histidine triad (HIT) protein, HitA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MSHDPNCLFCKIAAGAIPSTKVHEDDEFVAFRDIRPAAETHVLVIPRRHIATLSNCTGSDAPLLGRMLVLTARLADQLGV
AYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRMG

Sequences:

>Translated_121_residues
MSHDPNCLFCKIAAGAIPSTKVHEDDEFVAFRDIRPAAETHVLVIPRRHIATLSNCTGSDAPLLGRMLVLTARLADQLGV
AYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRMG
>Mature_120_residues
SHDPNCLFCKIAAGAIPSTKVHEDDEFVAFRDIRPAAETHVLVIPRRHIATLSNCTGSDAPLLGRMLVLTARLADQLGVA
YTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRMG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=108, Percent_Identity=41.6666666666667, Blast_Score=93, Evalue=5e-20,
Organism=Homo sapiens, GI14211923, Length=107, Percent_Identity=37.3831775700935, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787346, Length=112, Percent_Identity=44.6428571428571, Blast_Score=88, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17506713, Length=108, Percent_Identity=45.3703703703704, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24581222, Length=108, Percent_Identity=47.2222222222222, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28574010, Length=108, Percent_Identity=47.2222222222222, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 13038; Mature: 12907

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDPNCLFCKIAAGAIPSTKVHEDDEFVAFRDIRPAAETHVLVIPRRHIATLSNCTGSD
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHHHHCCCCCCC
APLLGRMLVLTARLADQLGVAYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRM
CCHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCC
G
C
>Mature Secondary Structure 
SHDPNCLFCKIAAGAIPSTKVHEDDEFVAFRDIRPAAETHVLVIPRRHIATLSNCTGSD
CCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHHHHCCCCCCC
APLLGRMLVLTARLADQLGVAYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRM
CCHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA