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The map label for this gene is mraW [H]

Identifier: 91785301

GI number: 91785301

Start: 4352130

End: 4353083

Strand: Reverse

Name: mraW [H]

Synonym: Bxe_A0478

Alternate gene names: 91785301

Gene position: 4353083-4352130 (Counterclockwise)

Preceding gene: 91785302

Following gene: 91785300

Centisome position: 88.91

GC content: 62.89

Gene sequence:

>954_bases
ATGGCACCTGCGATGGGAAATGAATTGCAGCATCGCACGGTGCTGCTGGAAGAAGCGGTTCAGGCGCTGGTCACGCGCGC
GGACGGCGTGTATGTGGACGGCACGTTCGGGCGCGGTGGTCATAGCCGGCTGGTGTTGGAGAAGTTGGGTGAGTCGGGGC
GTCTGATCGCTTTCGACAAAGACCCGCTCGCCATCGCCACGGCTCAGCAAATCACGGATCCGCGCTTTGGCATCGTGCAC
GAGAGTTTTGCTTCACTGCGCACCGCAATGGCGGAGCGCGGCGTAGGGCGGGTGTCGGGCGTTTTATTGGATCTGGGCGT
ATCGTCGCCGCAAGTCGACGATCCGGAGCGGGGCTTCAGCTTTCGCGCCGACGGCCCGCTCGACATGCGGATGGACCCGA
CGCGCGGCGAATCGGCGGCTGACTGGCTGGCGCGGGCCACGGTGCAGGAATTGACGGAGGTGATACGAGATTATGGGGAA
GAACGGTTTGCTTTTCAGATTGCAAAGGCGCTTGTTGCTCGCCGGGCAGAGTCCGACCGTCTTGGGCCTCTCGTCAGCAC
GGGCGAGCTTGCCCAAATCGTGGCTAACGTCGTCAAGACCCGTGAGAAGGGCAAGGATCCGGCAACCCGCACCTTTCAAG
CTATACGGATTCACATCAATCAAGAGCTTGCGGAGCTGCAAGTCGTTTTAGAAGCGGCGTTGTCGCTGTTGGAGCAAGGG
GGGCGGCTGGTGGTCATCAGCTTTCATTCGCTCGAAGACCGGATCGTCAAGCGATTCATGCAGGCGCACGCGAGTACGCC
GGCGGTGGACCGCCGTCTGCCGATTCGCGCAGTCGATCTGCCGAGCCCTCCGCTCAAGATCATCGGCCGCGTGTTCGCGA
GCGACGCTGAAGTCGCCGCGAACCCGCGCGCCCGTTCTGCCGTGATGCGCGTGGCGGAGCGGATCGCACCATGA

Upstream 100 bases:

>100_bases
GTGGGATGCACAGACATACACCGCGAAGGAACAGGCGGCAATGGCAGAGGGCATGCCCGATGCCTTGAAAGATTTCACGT
TCTGATCGCGGTTTACATAT

Downstream 100 bases:

>100_bases
ACCGCCTCAATATCTTCCTGCTGATTATCGTGATGGGCTGCGCCTTGTCGGTCGTCAACGCCACCAATCAGCAGCGCCAG
ATCTTTATCCAGTTGCAGCG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MAPAMGNELQHRTVLLEEAVQALVTRADGVYVDGTFGRGGHSRLVLEKLGESGRLIAFDKDPLAIATAQQITDPRFGIVH
ESFASLRTAMAERGVGRVSGVLLDLGVSSPQVDDPERGFSFRADGPLDMRMDPTRGESAADWLARATVQELTEVIRDYGE
ERFAFQIAKALVARRAESDRLGPLVSTGELAQIVANVVKTREKGKDPATRTFQAIRIHINQELAELQVVLEAALSLLEQG
GRLVVISFHSLEDRIVKRFMQAHASTPAVDRRLPIRAVDLPSPPLKIIGRVFASDAEVAANPRARSAVMRVAERIAP

Sequences:

>Translated_317_residues
MAPAMGNELQHRTVLLEEAVQALVTRADGVYVDGTFGRGGHSRLVLEKLGESGRLIAFDKDPLAIATAQQITDPRFGIVH
ESFASLRTAMAERGVGRVSGVLLDLGVSSPQVDDPERGFSFRADGPLDMRMDPTRGESAADWLARATVQELTEVIRDYGE
ERFAFQIAKALVARRAESDRLGPLVSTGELAQIVANVVKTREKGKDPATRTFQAIRIHINQELAELQVVLEAALSLLEQG
GRLVVISFHSLEDRIVKRFMQAHASTPAVDRRLPIRAVDLPSPPLKIIGRVFASDAEVAANPRARSAVMRVAERIAP
>Mature_316_residues
APAMGNELQHRTVLLEEAVQALVTRADGVYVDGTFGRGGHSRLVLEKLGESGRLIAFDKDPLAIATAQQITDPRFGIVHE
SFASLRTAMAERGVGRVSGVLLDLGVSSPQVDDPERGFSFRADGPLDMRMDPTRGESAADWLARATVQELTEVIRDYGEE
RFAFQIAKALVARRAESDRLGPLVSTGELAQIVANVVKTREKGKDPATRTFQAIRIHINQELAELQVVLEAALSLLEQGG
RLVVISFHSLEDRIVKRFMQAHASTPAVDRRLPIRAVDLPSPPLKIIGRVFASDAEVAANPRARSAVMRVAERIAP

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=341, Percent_Identity=38.1231671554252, Blast_Score=184, Evalue=6e-47,
Organism=Homo sapiens, GI165377202, Length=198, Percent_Identity=38.8888888888889, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1786270, Length=314, Percent_Identity=54.7770700636943, Blast_Score=338, Evalue=2e-94,
Organism=Drosophila melanogaster, GI62472493, Length=331, Percent_Identity=39.2749244712991, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI28571637, Length=331, Percent_Identity=39.2749244712991, Blast_Score=175, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 34552; Mature: 34421

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPAMGNELQHRTVLLEEAVQALVTRADGVYVDGTFGRGGHSRLVLEKLGESGRLIAFDK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCCCCEEEECC
DPLAIATAQQITDPRFGIVHESFASLRTAMAERGVGRVSGVLLDLGVSSPQVDDPERGFS
CCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCCCCCCCCCCC
FRADGPLDMRMDPTRGESAADWLARATVQELTEVIRDYGEERFAFQIAKALVARRAESDR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
LGPLVSTGELAQIVANVVKTREKGKDPATRTFQAIRIHINQELAELQVVLEAALSLLEQG
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRLVVISFHSLEDRIVKRFMQAHASTPAVDRRLPIRAVDLPSPPLKIIGRVFASDAEVAA
CCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHC
NPRARSAVMRVAERIAP
CCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
APAMGNELQHRTVLLEEAVQALVTRADGVYVDGTFGRGGHSRLVLEKLGESGRLIAFDK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCCCCEEEECC
DPLAIATAQQITDPRFGIVHESFASLRTAMAERGVGRVSGVLLDLGVSSPQVDDPERGFS
CCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCCCCCCCCCCC
FRADGPLDMRMDPTRGESAADWLARATVQELTEVIRDYGEERFAFQIAKALVARRAESDR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
LGPLVSTGELAQIVANVVKTREKGKDPATRTFQAIRIHINQELAELQVVLEAALSLLEQG
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRLVVISFHSLEDRIVKRFMQAHASTPAVDRRLPIRAVDLPSPPLKIIGRVFASDAEVAA
CCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHC
NPRARSAVMRVAERIAP
CCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA