| Definition | Burkholderia xenovorans LB400 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007951 |
| Length | 4,895,836 |
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The map label for this gene is secA [H]
Identifier: 91785284
GI number: 91785284
Start: 4330489
End: 4333299
Strand: Reverse
Name: secA [H]
Synonym: Bxe_A0495
Alternate gene names: 91785284
Gene position: 4333299-4330489 (Counterclockwise)
Preceding gene: 91785286
Following gene: 91785283
Centisome position: 88.51
GC content: 63.25
Gene sequence:
>2811_bases ATGACCACCGGTTTTCTACAGAAGATTTTTGGCAGCCGCAACCAGCGGCTAGTCAAGCAATATCAAAAGACCGTCGCGGC GATCAATGCGCTCGAGCCGCAGATCGAGCAATTGACGGACGACCAACTGCGCGGCAAAACGGGTGAATTCCGCCAGCGCG TCGCGAGCGGCGAGTCGCTCGACAAGCTCCTGCCCGAAGCCTTCGCGGTGTGCCGCGAAGCCAGCAAGCGGGTGCTGAAA ATGCGCCACTTCGACGTGCAGCTGATCGGCGGCATGGTTCTGCACTACGGCAAGATCGGCGAAATGCGCACGGGCGAGGG CAAGACGCTCGTCGCCACGCTGCCGGTGTACCTGAACGCGTTGTCGGGCCGCGGCGTGCACGTCGTCACGGTCAACGACT ACCTGGCCCAGCGCGACGCCGAATGGATGGCGCGGCTGTACAACTTCCTCGGTCTGTCGGTCGGTATCAATCTGTCGCAG ATGGATCACGCCGCGAAGCAGGAAGCCTACGCGGCGGACATCACCTACGGCACGAACAACGAATTCGGCTTCGACTACCT GCGCGACAACATGGTCTACGAGACCGACGCGCGCGTGCAGCGAGCCCTGAATTTCGCGGTGGTCGACGAGGTCGACTCGA TCCTGATCGACGAAGCCCGCACGCCGCTGATCATCTCCGGCCAGGCCGAAGATCACACCGAGCTCTACGTGCGCATGAAC GCGCTGCCGCCGCTGCTGGAGCGCCAGATCGGCGAAGAGAAAGCGGACGGCACCGGCGTAGAAAAGCCGGGCGACTACAC GCTGGACGAAAAAGGCCGCCAGGTGTTCCTCACGGAATCGGGCCACGAAAAGGCCGAGCGCCTGCTCTCCGAGTGGGGTC TGATCGGCGAGGGCGAAAGCCTGTACGCGCCGCAGAACATCACGCTGATGCACCACGTGTACGCCGCGCTGCGCGCGCAC ACGCTGTTCTTCAAGGACCAGCATTACGTCGTGCAGAACGGCGAGGTGGTGATCGTCGACGAATTCACCGGCCGCCTGAT GTCGGGCCGCCGTTGGTCGGACGGCCTGCACCAGGCTGTCGAGGCGAAGGAACACGTCAAGATCCAGAGCGAGAACCAGA CGCTCGCGTCGATCACGTTCCAGAACTACTTCCGCATGTACGCGAAGCTGTCCGGCATGACCGGCACGGCGGATACCGAA GCCTACGAATTCAACGAGATCTACGGGCTCGAAACGGTCGTGATCCCGACCAACCGTCCGCCCAAGCGGATCGACAAGCA GGATCAGATCTACAAGACCGCCAAGGAACGCTACGACGCGGTGATCCGCGACATTCGCGATTGCTATGAGCGCGGTCAGC CGGTGCTGGTCGGTACTACGTCGATCGAAAACTCCGAGTTGCTGTCGCATCTGCTGAAGCAGGCCGGTTTGCCGCACGAA GTGCTGAACGCCAAGCAGCACGCGCGTGAAGCCGAGATCGTCGCCGAAGCCGGCCGTCCGAAGCGCATTACGATCGCCAC CAACATGGCCGGTCGCGGTACGGACATCGTGCTCGGCGGCAATGCGGAAAAGCAGGCGTCGTTCCTCGAACTGGACGAAA CGCTGCCGGAAGACGAAAAGCGGCGCCGTATCCAGAAGCTGCACGACGAATGGCAGGCGCTGCACGATCAGGTGAAGGCC GCGGGCGGCCTGCACATCATCGGCACCGAGCGTCACGAGTCGCGCCGGATCGACAACCAGTTGCGCGGCCGTGCCGGCCG TCAGGGCGACCCGGGTTCGTCGCGCTTCTATCTGTCGCTGGAAGACCCGCTGCTGCGCATTTTCGCCGGCGACCGCGTGC GCGCGATCATGGAACGCCTGAAGATGCCGGAAGGCGAAGCGATCGAGGCCGGCATCGTCTCGCGCTCCATCGAGTCGGCG CAGCGCAAGGTCGAAGCGCGCAACTTCGACATTCGCAAGCAATTGCTCGAATACGACGACGTGTCGAACGATCAGCGCAA GGTGATCTACCAGCAGCGCAATGAATTGCTCGAAGCGAACGACATCACCGAAACGATCGGCGCGATGCGCCAGAGCGTGA TCGCCGATATCGTCCACCAGTTCGTGCCGGCCGGCAGCATTGAAGAGCAGTGGGACGTGCCCGAGCTGGAGGAAGTGCTG CGCAACGAGTGGCAGCTCGACCTCGCGATCCAGGAAATGATCAACGAGTCGAACTCGATCAGCGCCGACGAGATTCTCGA AGCGGTTGAAGCCGCGGCAGACGAAGCGTACGAAGCGAAGGTCGAACTGGTCGGCCGCGAGTCGTTCAGCGCGTTCGAGC GCTCGATCATGCTGCAAACGCTGGACCGTAGCTGGCGCGAACATCTGGCCGCGCTCGACCATCTGCGCCAGGGCATCCAT CTGCGCGGCTATGCGCAGAAGAACCCGAAGCAGGAATACAAGCGCGAGGCGTTCGAACTGTTCGCCGCGATGCTCGACGC CGTGAAGCTCGAAGTCACCCGCGTGGTGATGAACGTGCAGATCCAGTCGCCGGAACAGCTGGAACAGGCCGCCGAACAGT TGGAAGAGCAGGGCAGCCACCTGGAGAACGTCGAGTTCCGTCACGCCGAATTCGCCGAAGCCGCTGCGGCGGCGCCGGTC GCCGCGGAGGCGGCCACCGCCGCCATGATCGGCGACGCGATGAGCCACGGCTCGTCGCAGGCGGCCGCAGCGAACATGAG CGCGGACAACGTGCCGAAGGTCGGCCGTAACGACCCGTGCCCGTGCGGCAGCGGCAAGAAGTACAAGCAGTGCCACGGCA AGATCGTGTAA
Upstream 100 bases:
>100_bases CTCTTGGACTAAGCCGCCGAGGCCCTTCTGACCCCCGGAGCGCACGTGCACGAATTGCACGGCGCGACCCAGCCGAAGCC GCGACGCAGACACCGATCCG
Downstream 100 bases:
>100_bases TGCCGAAGGCGGCGCGCTGCGAGGCGCGCCGCGTCGTTTTTGCGCGGTAGCTTGTCCCGATTTCGCGGTGGTCCGGCAGC ATGCCCGGGCCATCAGTTTC
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 936; Mature: 935
Protein sequence:
>936_residues MTTGFLQKIFGSRNQRLVKQYQKTVAAINALEPQIEQLTDDQLRGKTGEFRQRVASGESLDKLLPEAFAVCREASKRVLK MRHFDVQLIGGMVLHYGKIGEMRTGEGKTLVATLPVYLNALSGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSQ MDHAAKQEAYAADITYGTNNEFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN ALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERLLSEWGLIGEGESLYAPQNITLMHHVYAALRAH TLFFKDQHYVVQNGEVVIVDEFTGRLMSGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTE AYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHE VLNAKQHAREAEIVAEAGRPKRITIATNMAGRGTDIVLGGNAEKQASFLELDETLPEDEKRRRIQKLHDEWQALHDQVKA AGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLLRIFAGDRVRAIMERLKMPEGEAIEAGIVSRSIESA QRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEANDITETIGAMRQSVIADIVHQFVPAGSIEEQWDVPELEEVL RNEWQLDLAIQEMINESNSISADEILEAVEAAADEAYEAKVELVGRESFSAFERSIMLQTLDRSWREHLAALDHLRQGIH LRGYAQKNPKQEYKREAFELFAAMLDAVKLEVTRVVMNVQIQSPEQLEQAAEQLEEQGSHLENVEFRHAEFAEAAAAAPV AAEAATAAMIGDAMSHGSSQAAAANMSADNVPKVGRNDPCPCGSGKKYKQCHGKIV
Sequences:
>Translated_936_residues MTTGFLQKIFGSRNQRLVKQYQKTVAAINALEPQIEQLTDDQLRGKTGEFRQRVASGESLDKLLPEAFAVCREASKRVLK MRHFDVQLIGGMVLHYGKIGEMRTGEGKTLVATLPVYLNALSGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSQ MDHAAKQEAYAADITYGTNNEFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN ALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERLLSEWGLIGEGESLYAPQNITLMHHVYAALRAH TLFFKDQHYVVQNGEVVIVDEFTGRLMSGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTE AYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHE VLNAKQHAREAEIVAEAGRPKRITIATNMAGRGTDIVLGGNAEKQASFLELDETLPEDEKRRRIQKLHDEWQALHDQVKA AGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLLRIFAGDRVRAIMERLKMPEGEAIEAGIVSRSIESA QRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEANDITETIGAMRQSVIADIVHQFVPAGSIEEQWDVPELEEVL RNEWQLDLAIQEMINESNSISADEILEAVEAAADEAYEAKVELVGRESFSAFERSIMLQTLDRSWREHLAALDHLRQGIH LRGYAQKNPKQEYKREAFELFAAMLDAVKLEVTRVVMNVQIQSPEQLEQAAEQLEEQGSHLENVEFRHAEFAEAAAAAPV AAEAATAAMIGDAMSHGSSQAAAANMSADNVPKVGRNDPCPCGSGKKYKQCHGKIV >Mature_935_residues TTGFLQKIFGSRNQRLVKQYQKTVAAINALEPQIEQLTDDQLRGKTGEFRQRVASGESLDKLLPEAFAVCREASKRVLKM RHFDVQLIGGMVLHYGKIGEMRTGEGKTLVATLPVYLNALSGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSQM DHAAKQEAYAADITYGTNNEFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMNA LPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERLLSEWGLIGEGESLYAPQNITLMHHVYAALRAHT LFFKDQHYVVQNGEVVIVDEFTGRLMSGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTEA YEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHEV LNAKQHAREAEIVAEAGRPKRITIATNMAGRGTDIVLGGNAEKQASFLELDETLPEDEKRRRIQKLHDEWQALHDQVKAA GGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLLRIFAGDRVRAIMERLKMPEGEAIEAGIVSRSIESAQ RKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEANDITETIGAMRQSVIADIVHQFVPAGSIEEQWDVPELEEVLR NEWQLDLAIQEMINESNSISADEILEAVEAAADEAYEAKVELVGRESFSAFERSIMLQTLDRSWREHLAALDHLRQGIHL RGYAQKNPKQEYKREAFELFAAMLDAVKLEVTRVVMNVQIQSPEQLEQAAEQLEEQGSHLENVEFRHAEFAEAAAAAPVA AEAATAAMIGDAMSHGSSQAAAANMSADNVPKVGRNDPCPCGSGKKYKQCHGKIV
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=937, Percent_Identity=58.9114194236926, Blast_Score=1100, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004027 - InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 105122; Mature: 104991
Theoretical pI: Translated: 5.16; Mature: 5.16
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTGFLQKIFGSRNQRLVKQYQKTVAAINALEPQIEQLTDDQLRGKTGEFRQRVASGESL CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHCCCCHHHHHHHHCCCHH DKLLPEAFAVCREASKRVLKMRHFDVQLIGGMVLHYGKIGEMRTGEGKTLVATLPVYLNA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHH LSGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSQMDHAAKQEAYAADITYGTNN HCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCC EFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN CCCHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEC ALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERLLSEWGLIGEGES CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCC LYAPQNITLMHHVYAALRAHTLFFKDQHYVVQNGEVVIVDEFTGRLMSGRRWSDGLHQAV EECCCCCHHHHHHHHHHHHHHHEEECCEEEEECCCEEEEECCHHHHHCCCCCHHHHHHHH EAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTEAYEFNEIYGLETVVIPTNRP HHHHHCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCEEEEECCCCC PKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHE HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHH VLNAKQHAREAEIVAEAGRPKRITIATNMAGRGTDIVLGGNAEKQASFLELDETLPEDEK HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHH RRRIQKLHDEWQALHDQVKAAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSL HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE EDPLLRIFAGDRVRAIMERLKMPEGEAIEAGIVSRSIESAQRKVEARNFDIRKQLLEYDD CCCHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC VSNDQRKVIYQQRNELLEANDITETIGAMRQSVIADIVHQFVPAGSIEEQWDVPELEEVL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH RNEWQLDLAIQEMINESNSISADEILEAVEAAADEAYEAKVELVGRESFSAFERSIMLQT HCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH LDRSWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLDAVKLEVTRVVMNVQ HHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE IQSPEQLEQAAEQLEEQGSHLENVEFRHAEFAEAAAAAPVAAEAATAAMIGDAMSHGSSQ ECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCH AAAANMSADNVPKVGRNDPCPCGSGKKYKQCHGKIV HHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC >Mature Secondary Structure TTGFLQKIFGSRNQRLVKQYQKTVAAINALEPQIEQLTDDQLRGKTGEFRQRVASGESL CHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHCCCCHHHHHHHHCCCHH DKLLPEAFAVCREASKRVLKMRHFDVQLIGGMVLHYGKIGEMRTGEGKTLVATLPVYLNA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHH LSGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSQMDHAAKQEAYAADITYGTNN HCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCC EFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN CCCHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEC ALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERLLSEWGLIGEGES CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCC LYAPQNITLMHHVYAALRAHTLFFKDQHYVVQNGEVVIVDEFTGRLMSGRRWSDGLHQAV EECCCCCHHHHHHHHHHHHHHHEEECCEEEEECCCEEEEECCHHHHHCCCCCHHHHHHHH EAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTEAYEFNEIYGLETVVIPTNRP HHHHHCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCEEEEECCCCC PKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHE HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHH VLNAKQHAREAEIVAEAGRPKRITIATNMAGRGTDIVLGGNAEKQASFLELDETLPEDEK HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHH RRRIQKLHDEWQALHDQVKAAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSL HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE EDPLLRIFAGDRVRAIMERLKMPEGEAIEAGIVSRSIESAQRKVEARNFDIRKQLLEYDD CCCHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC VSNDQRKVIYQQRNELLEANDITETIGAMRQSVIADIVHQFVPAGSIEEQWDVPELEEVL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH RNEWQLDLAIQEMINESNSISADEILEAVEAAADEAYEAKVELVGRESFSAFERSIMLQT HCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH LDRSWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLDAVKLEVTRVVMNVQ HHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE IQSPEQLEQAAEQLEEQGSHLENVEFRHAEFAEAAAAAPVAAEAATAAMIGDAMSHGSSQ ECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCH AAAANMSADNVPKVGRNDPCPCGSGKKYKQCHGKIV HHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA