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The map label for this gene is nrdB [H]

Identifier: 91785256

GI number: 91785256

Start: 4302412

End: 4303647

Strand: Reverse

Name: nrdB [H]

Synonym: Bxe_A0523

Alternate gene names: 91785256

Gene position: 4303647-4302412 (Counterclockwise)

Preceding gene: 91785257

Following gene: 91785255

Centisome position: 87.9

GC content: 59.3

Gene sequence:

>1236_bases
ATGCTCAACTGGGATGACGAGATCACTGCCGTAACTCCCTCGAGCGCTACGCAACAGAATGTGTTGCGCAACGCTGCGGG
ACCGGCTGTCGGTTCGCAAGTCGGAACGCGTTCCGCTCCTCATGCTCCCTCGGCTCAAGACGTCTTCGCGAACGACATTG
CTGTCGCTCCCGTCGCTCATGTGACCCACGCTGCGGCTGGAACGGCTGCCGTTTCGGAAGCGCGGGTCAACGTCGCCGAC
AAGCGCATCATCAACGGCCAGACCGACGTCAATCAGTTGGTGCCGTTCAAATACAAGTGGGCGTGGGAAAAGTATCTGGC
TGGTTGTGCCAACCACTGGATGCCGCAAGAAGTGAACATGTCGCGTGACATCGCCCTCTGGAAAGACCCGAACGGTCTGA
CCGAAGACGAGCGCCGCATCGTCAAGCGCAACCTGGGCTTCTTCGTGACGGCCGATTCCCTCGCCGCCAACAATATCGTG
CTGGGCACCTACCGCCACATCACGGCGCCCGAATGCCGCCAGTTCCTGCTGCGCCAGGCGTTCGAAGAGGCGATCCACAC
GCACGCCTACCAGTACATCGTCGAATCGCTGGGCCTCGACGAAGGCGAAATCTTCAACGCGTATCACGAGGTCTCCTCGA
TCCGCGCGAAAGACGAATTCCTGATTCCGTACATCCACGTGCTGACCGATCCGGCCTTCAAGACCGGCACGCTCGAAGCA
GACCAGACGCTCCTGCGCTCGCTGATCGTGTTCGCCTGTGTGATGGAAGGGCTGTTCTTCTACGTCGGCTTTACCCAGAT
CCTGGCGCTGGGTCGCCAGAACAAGATGACGGGCGCGGCGGAACAGTACCAGTACATCCTGCGCGACGAGTCGATGCACT
GTAACTTCGGCATCGACCTGATCAACCAGATCAAACTCGAAAACCCGCAACTCTGGACGGCTGAGTTCCGCGCGGAAATC
CGCGAGATCTTCCAGCAGGCGGTCGAACTCGAATATCGTTACGCAGAAGACACGATGCCGCGCGGGGTGCTCGGCCTCAA
TGCGTCGATGTTCAAGAGCTATCTGCGCTTCATCTGCAACCGCCGTTGCCAGCAGATCGGTCTCGATCCGCTGTACCCGA
ACGAGGAAAACCCGTTCCCGTGGATGAGCGAGATGATCGACCTGAAGAAGGAACGAAACTTCTTCGAGACGCGAGTGATC
GAATATCAGACTGGCGGCGCGCTGACCTGGGAGTGA

Upstream 100 bases:

>100_bases
AACGTAGCAACGCGAATCGAAAACAGGATTTTTCATCAGCGAACTCTTTTATCGCTCGTGAAAAGATGGTACAAACCGTT
CTAAATTGATGGTGACATTT

Downstream 100 bases:

>100_bases
TCCGGGTTCGTGCTGCAGATGCATTCATCGATGGGGATGCCGCTGGCTTGGGCCGCGGCAATTTTGGCTAGGAGCAGAAT
CGCCTGATGCAAAGCATGCC

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLNWDDEITAVTPSSATQQNVLRNAAGPAVGSQVGTRSAPHAPSAQDVFANDIAVAPVAHVTHAAAGTAAVSEARVNVAD
KRIINGQTDVNQLVPFKYKWAWEKYLAGCANHWMPQEVNMSRDIALWKDPNGLTEDERRIVKRNLGFFVTADSLAANNIV
LGTYRHITAPECRQFLLRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVSSIRAKDEFLIPYIHVLTDPAFKTGTLEA
DQTLLRSLIVFACVMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPQLWTAEFRAEI
REIFQQAVELEYRYAEDTMPRGVLGLNASMFKSYLRFICNRRCQQIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVI
EYQTGGALTWE

Sequences:

>Translated_411_residues
MLNWDDEITAVTPSSATQQNVLRNAAGPAVGSQVGTRSAPHAPSAQDVFANDIAVAPVAHVTHAAAGTAAVSEARVNVAD
KRIINGQTDVNQLVPFKYKWAWEKYLAGCANHWMPQEVNMSRDIALWKDPNGLTEDERRIVKRNLGFFVTADSLAANNIV
LGTYRHITAPECRQFLLRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVSSIRAKDEFLIPYIHVLTDPAFKTGTLEA
DQTLLRSLIVFACVMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPQLWTAEFRAEI
REIFQQAVELEYRYAEDTMPRGVLGLNASMFKSYLRFICNRRCQQIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVI
EYQTGGALTWE
>Mature_411_residues
MLNWDDEITAVTPSSATQQNVLRNAAGPAVGSQVGTRSAPHAPSAQDVFANDIAVAPVAHVTHAAAGTAAVSEARVNVAD
KRIINGQTDVNQLVPFKYKWAWEKYLAGCANHWMPQEVNMSRDIALWKDPNGLTEDERRIVKRNLGFFVTADSLAANNIV
LGTYRHITAPECRQFLLRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVSSIRAKDEFLIPYIHVLTDPAFKTGTLEA
DQTLLRSLIVFACVMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPQLWTAEFRAEI
REIFQQAVELEYRYAEDTMPRGVLGLNASMFKSYLRFICNRRCQQIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVI
EYQTGGALTWE

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI289177074, Length=344, Percent_Identity=26.7441860465116, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI42544136, Length=340, Percent_Identity=26.7647058823529, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4557845, Length=381, Percent_Identity=27.5590551181102, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI260064013, Length=381, Percent_Identity=27.5590551181102, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI289177076, Length=290, Percent_Identity=28.9655172413793, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1788567, Length=297, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17551968, Length=398, Percent_Identity=27.1356783919598, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI193206379, Length=304, Percent_Identity=23.3552631578947, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17567153, Length=224, Percent_Identity=28.125, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322434, Length=331, Percent_Identity=30.5135951661631, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6321619, Length=318, Percent_Identity=22.9559748427673, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18079279, Length=320, Percent_Identity=28.4375, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 46644; Mature: 46644

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNWDDEITAVTPSSATQQNVLRNAAGPAVGSQVGTRSAPHAPSAQDVFANDIAVAPVAH
CCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHH
VTHAAAGTAAVSEARVNVADKRIINGQTDVNQLVPFKYKWAWEKYLAGCANHWMPQEVNM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCC
SRDIALWKDPNGLTEDERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQFLLRQA
CCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHH
FEEAIHTHAYQYIVESLGLDEGEIFNAYHEVSSIRAKDEFLIPYIHVLTDPAFKTGTLEA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCH
DQTLLRSLIVFACVMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHH
INQIKLENPQLWTAEFRAEIREIFQQAVELEYRYAEDTMPRGVLGLNASMFKSYLRFICN
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHH
RRCQQIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALTWE
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEEEEECCCCCCCC
>Mature Secondary Structure
MLNWDDEITAVTPSSATQQNVLRNAAGPAVGSQVGTRSAPHAPSAQDVFANDIAVAPVAH
CCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHH
VTHAAAGTAAVSEARVNVADKRIINGQTDVNQLVPFKYKWAWEKYLAGCANHWMPQEVNM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCC
SRDIALWKDPNGLTEDERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQFLLRQA
CCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHH
FEEAIHTHAYQYIVESLGLDEGEIFNAYHEVSSIRAKDEFLIPYIHVLTDPAFKTGTLEA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCH
DQTLLRSLIVFACVMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHH
INQIKLENPQLWTAEFRAEIREIFQQAVELEYRYAEDTMPRGVLGLNASMFKSYLRFICN
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHH
RRCQQIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALTWE
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]