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The map label for this gene is aroE [H]

Identifier: 91785240

GI number: 91785240

Start: 4287377

End: 4288240

Strand: Reverse

Name: aroE [H]

Synonym: Bxe_A0539

Alternate gene names: 91785240

Gene position: 4288240-4287377 (Counterclockwise)

Preceding gene: 91785241

Following gene: 91785239

Centisome position: 87.59

GC content: 67.82

Gene sequence:

>864_bases
ATGAGCGCCGGCGATTCACTCGACCGGTACGCGGTTATCGGCAATCCGGTCGGCCACAGCAAGTCACCGTTCATTCACGG
CCGCTTTGCCGAGCAGACCGGCGAGGCTATCGAGTATGGCCGCCTGCTCGCGCCGGTGGATGCGTTCGTGCCCACCGTGC
GGGCTTTCATCGAAGCAGGCGGGCGCGGCCTGAACGTGACCGTGCCGTTCAAGCTCGAAGCGTGTACGTTCGCCGACACG
TTGTCGCCGCGCGCGGCCGCCGCGGGCGCGGTGAACACGTTGCGCGTCGATGCGAACGGTATTTACGGCGACAACACCGA
TGGCTTTGGTCTCGTGCGCGATATCGAGGTGAATCTCGGCGTGTCCCTGAAGGGCGCGCGCATTCTGTTGCTGGGTGCGG
GCGGCGCCGCGCGCGGCGTGGTTCTGCCGATATTGGAGCGGGCGCCGCATACGCTGACCATCATCAATCGCACCGCGCAG
AAGGCCGAAGCGCTGGTCGATCAGTTCGCGCAGGCCGCGCGCGACGCCGCGTGCCGGCTGGGCGGCGGCAGCGCGCGGGC
GATCGAAGCGGGCGCGTATGACGTGATCGTGAACGCCACGGCGGGGAGCCTGGACGCGTCGTTGCCCGAGTGCGACGACC
GAGCGTTCGGCAGCGGCACACTCGCTTACGACATGATGTATGGCGCGCATCCCACGGTGTTCATGGAACACGCGCGGAAA
CTGGGCGCGCGCGGTGCAGATGGACTCGGCATGCTGGTCGAGCAGGCCGCCGAATCGTTTTATGTGTGGCGCGGCGTGCG
GCCTGACGGCGCGCCGGTGCTGGCCGAATTGCGGGCGCTGTTGACGGCGCCGTCGCACGCATAA

Upstream 100 bases:

>100_bases
GCGAGGCGGCGGCCGCGCCGAACGACGCCGCAAATGGCGAAGGCGAGGGCGAAAGCGCGAGCGATGCCGCCACGCATCGG
CACGTCGCGGAGCCGGGACG

Downstream 100 bases:

>100_bases
AGTTGCGCATCACCTTGCCGCATTCACCGACACGAGGATCTCGAGCACGATGACAGCAACGCGGCGCGTGAGCCGGCCAG
GTCCGGTGCGATGGATGTTT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MSAGDSLDRYAVIGNPVGHSKSPFIHGRFAEQTGEAIEYGRLLAPVDAFVPTVRAFIEAGGRGLNVTVPFKLEACTFADT
LSPRAAAAGAVNTLRVDANGIYGDNTDGFGLVRDIEVNLGVSLKGARILLLGAGGAARGVVLPILERAPHTLTIINRTAQ
KAEALVDQFAQAARDAACRLGGGSARAIEAGAYDVIVNATAGSLDASLPECDDRAFGSGTLAYDMMYGAHPTVFMEHARK
LGARGADGLGMLVEQAAESFYVWRGVRPDGAPVLAELRALLTAPSHA

Sequences:

>Translated_287_residues
MSAGDSLDRYAVIGNPVGHSKSPFIHGRFAEQTGEAIEYGRLLAPVDAFVPTVRAFIEAGGRGLNVTVPFKLEACTFADT
LSPRAAAAGAVNTLRVDANGIYGDNTDGFGLVRDIEVNLGVSLKGARILLLGAGGAARGVVLPILERAPHTLTIINRTAQ
KAEALVDQFAQAARDAACRLGGGSARAIEAGAYDVIVNATAGSLDASLPECDDRAFGSGTLAYDMMYGAHPTVFMEHARK
LGARGADGLGMLVEQAAESFYVWRGVRPDGAPVLAELRALLTAPSHA
>Mature_286_residues
SAGDSLDRYAVIGNPVGHSKSPFIHGRFAEQTGEAIEYGRLLAPVDAFVPTVRAFIEAGGRGLNVTVPFKLEACTFADTL
SPRAAAAGAVNTLRVDANGIYGDNTDGFGLVRDIEVNLGVSLKGARILLLGAGGAARGVVLPILERAPHTLTIINRTAQK
AEALVDQFAQAARDAACRLGGGSARAIEAGAYDVIVNATAGSLDASLPECDDRAFGSGTLAYDMMYGAHPTVFMEHARKL
GARGADGLGMLVEQAAESFYVWRGVRPDGAPVLAELRALLTAPSHA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=279, Percent_Identity=46.9534050179211, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI1787983, Length=273, Percent_Identity=28.9377289377289, Blast_Score=102, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=161, Percent_Identity=31.055900621118, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29845; Mature: 29714

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGDSLDRYAVIGNPVGHSKSPFIHGRFAEQTGEAIEYGRLLAPVDAFVPTVRAFIEAG
CCCCCCCCCEEEECCCCCCCCCCEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GRGLNVTVPFKLEACTFADTLSPRAAAAGAVNTLRVDANGIYGDNTDGFGLVRDIEVNLG
CCCEEEEEEEEEEEEEHHHCCCCHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEEEEECC
VSLKGARILLLGAGGAARGVVLPILERAPHTLTIINRTAQKAEALVDQFAQAARDAACRL
EEECCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEC
GGGSARAIEAGAYDVIVNATAGSLDASLPECDDRAFGSGTLAYDMMYGAHPTVFMEHARK
CCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHH
LGARGADGLGMLVEQAAESFYVWRGVRPDGAPVLAELRALLTAPSHA
HCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SAGDSLDRYAVIGNPVGHSKSPFIHGRFAEQTGEAIEYGRLLAPVDAFVPTVRAFIEAG
CCCCCCCCEEEECCCCCCCCCCEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GRGLNVTVPFKLEACTFADTLSPRAAAAGAVNTLRVDANGIYGDNTDGFGLVRDIEVNLG
CCCEEEEEEEEEEEEEHHHCCCCHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEEEEECC
VSLKGARILLLGAGGAARGVVLPILERAPHTLTIINRTAQKAEALVDQFAQAARDAACRL
EEECCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEC
GGGSARAIEAGAYDVIVNATAGSLDASLPECDDRAFGSGTLAYDMMYGAHPTVFMEHARK
CCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHH
LGARGADGLGMLVEQAAESFYVWRGVRPDGAPVLAELRALLTAPSHA
HCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA