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The map label for this gene is erpA1

Identifier: 91785171

GI number: 91785171

Start: 4207141

End: 4207506

Strand: Reverse

Name: erpA1

Synonym: Bxe_A0609

Alternate gene names: 91785171

Gene position: 4207506-4207141 (Counterclockwise)

Preceding gene: 91785172

Following gene: 91785169

Centisome position: 85.94

GC content: 55.74

Gene sequence:

>366_bases
ATGAACGCAGTCACCGATACACCCGTGACCGAGATGCCCGCCCCCTTCGTTTTTACCGACGCAGCGGCTGACAAGGTCAA
GCAACTGATCGAAGAAGAAGGCAATGCGGACCTCAAACTGCGCGTTTTCGTGCAGGGCGGCGGCTGCTCGGGCTTTCAGT
ACGGTTTTACGTTTGACGAAGCCGTCAACGAAGACGACACCGTCATGAACAAGAGCGGCGTCCAGCTGCTGATCGATTCG
ATGAGCTACCAGTATTTGGTGGGCGCTGAGATCGACTACAAGGACGATATCAACGGCGCTCAGTTCGTCATCAAGAACCC
GAATGCTACGACCACCTGTGGTTGCGGCTCATCGTTCTCGGTGTGA

Upstream 100 bases:

>100_bases
ATCCATTGATTCTCTGGAAGAACCCATTGACTTTGTGGGCTTCGGCACGATATCGAGATCAGCCCTACAATAGCGGTTAG
AAGCTTTTTGGAGAGTTCGA

Downstream 100 bases:

>100_bases
CGACGGGTTGTTGAGCAGTTGATTGTGGCAAACGGGGCTTCGGCCCCGTTTCTTATTGCCTGCGCCGAAATCCGCGCCAC
GCTCAGCTCAGCGCGGGTAG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MNAVTDTPVTEMPAPFVFTDAAADKVKQLIEEEGNADLKLRVFVQGGGCSGFQYGFTFDEAVNEDDTVMNKSGVQLLIDS
MSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFSV

Sequences:

>Translated_121_residues
MNAVTDTPVTEMPAPFVFTDAAADKVKQLIEEEGNADLKLRVFVQGGGCSGFQYGFTFDEAVNEDDTVMNKSGVQLLIDS
MSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFSV
>Mature_121_residues
MNAVTDTPVTEMPAPFVFTDAAADKVKQLIEEEGNADLKLRVFVQGGGCSGFQYGFTFDEAVNEDDTVMNKSGVQLLIDS
MSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters (Potential)

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=98, Percent_Identity=42.8571428571429, Blast_Score=86, Evalue=8e-18,
Organism=Homo sapiens, GI52426768, Length=121, Percent_Identity=30.5785123966942, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786351, Length=111, Percent_Identity=59.4594594594595, Blast_Score=148, Evalue=1e-37,
Organism=Escherichia coli, GI1788877, Length=104, Percent_Identity=33.6538461538462, Blast_Score=66, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71998452, Length=105, Percent_Identity=37.1428571428571, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25146411, Length=114, Percent_Identity=29.8245614035088, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193209025, Length=112, Percent_Identity=30.3571428571429, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=82, Percent_Identity=40.2439024390244, Blast_Score=73, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24642263, Length=121, Percent_Identity=30.5785123966942, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA1_BURXL (Q13UB4)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_560377.1
- ProteinModelPortal:   Q13UB4
- SMR:   Q13UB4
- GeneID:   4005802
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A0609
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- ProtClustDB:   PRK13623
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 13026; Mature: 13026

Theoretical pI: Translated: 3.82; Mature: 3.82

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVTDTPVTEMPAPFVFTDAAADKVKQLIEEEGNADLKLRVFVQGGGCSGFQYGFTFDE
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEHHH
AVNEDDTVMNKSGVQLLIDSMSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFS
HCCCCCCEECCCCEEEEEECCCCEEEECCCCCCCCCCCCEEEEEECCCCCEEECCCCCCC
V
C
>Mature Secondary Structure
MNAVTDTPVTEMPAPFVFTDAAADKVKQLIEEEGNADLKLRVFVQGGGCSGFQYGFTFDE
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEHHH
AVNEDDTVMNKSGVQLLIDSMSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFS
HCCCCCCEECCCCEEEEEECCCCEEEECCCCCCCCCCCCEEEEEECCCCCEEECCCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA