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The map label for this gene is fabD [H]

Identifier: 91784719

GI number: 91784719

Start: 3706434

End: 3707369

Strand: Reverse

Name: fabD [H]

Synonym: Bxe_A1073

Alternate gene names: 91784719

Gene position: 3707369-3706434 (Counterclockwise)

Preceding gene: 91784720

Following gene: 91784718

Centisome position: 75.72

GC content: 64.74

Gene sequence:

>936_bases
ATGAAATTTGCGTTCGTTTTTCCTGGGCAAGGTTCGCAGTCGGTCGGCATGCTCAACGCATTCGCCGATCAGGCGGTCGT
GCGTGAGACGGTTCAGGAAGCCTCCGATGCGCTCAATCAGGACCTCGGCAAGCTGATCGCCGAAGGCCCTGCCGAAGATC
TGAACCTCACCACCAATACCCAGCCGGTCATGCTGACTGCCTCGTACGCCATGTATCGCGCGTGGCTGCAGGCTGGCGGC
CCGAAGCCGGCAATCGTCGCGGGCCACAGCCTGGGCGAATACACCGCGCTGGTCGCGGCGGGCGCGATTGCGTTTCGCGA
TGCCGTACCGCTCGTGCGGTTTCGCGCGCAAGCCATGCAAACGGCGGTGCCGGTCGGTGAAGGCGCAATGGCCGCGATTC
TCGGTCTCGACGACGATACGGTGCGCGCGGTGTGCGCTGAAGCGTCGGTTGCGGGTGTCGTCGAAGCGGTCAATTTCAAT
GCGCCGGCGCAGGTCGTGATCGCGGGCAACAAGGCTGCGGTCGAAAAGGCCTGCGAGGTCGCGAAGGCGAAGGGCGCCAA
GCGCGCGTTGCCGTTGCCGGTCTCGGCGCCGTTCCACTCGTCGCTGCTCAAGCCCGCGTCGGACCAGTTGCGCGAGTACC
TGGCGAGCGTCGACGTGCAGGTGCCGGCTATTCCGGTCATCAACAACGTGGACGTCGCCGTGGTCAACGAACCGGCCGCG
ATCAAAGACGCACTGGTGCGCCAGGCGGCCGGCGCGGTGCGCTGGGTCGAAAGCGTTCAGGCCATGTCGGCTCAAGGCGT
CACGCACGTGATCGAATGTGGTCCGGGCAAGGTCCTTGCGGGTTTGACCAAGCGTATCGACGGCAACCTGGTCGGTGCCT
CGATCTTCGATCCGGCTTCGCTCGAAGAGACGCTCAAACTCGTGAAGGCAGGCTGA

Upstream 100 bases:

>100_bases
GTGATGGCGAGCGCCCTTCGCGGCGCTCGACTACGCTTGAGCGCGCTCGCGTCAACCGGGCGCGCCACCCACATCTGACA
ACATCGATTTTGGGGACGAT

Downstream 100 bases:

>100_bases
ACGCAACGTCGCACCGCGTCTGGCAGCAGGCGCTTCGCGGCGGCGTCAGGACTGCGCATCAAGAATCAATCAGCCCTCCG
AAGGGCATCCGGACTGACAG

Product: [Acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKFAFVFPGQGSQSVGMLNAFADQAVVRETVQEASDALNQDLGKLIAEGPAEDLNLTTNTQPVMLTASYAMYRAWLQAGG
PKPAIVAGHSLGEYTALVAAGAIAFRDAVPLVRFRAQAMQTAVPVGEGAMAAILGLDDDTVRAVCAEASVAGVVEAVNFN
APAQVVIAGNKAAVEKACEVAKAKGAKRALPLPVSAPFHSSLLKPASDQLREYLASVDVQVPAIPVINNVDVAVVNEPAA
IKDALVRQAAGAVRWVESVQAMSAQGVTHVIECGPGKVLAGLTKRIDGNLVGASIFDPASLEETLKLVKAG

Sequences:

>Translated_311_residues
MKFAFVFPGQGSQSVGMLNAFADQAVVRETVQEASDALNQDLGKLIAEGPAEDLNLTTNTQPVMLTASYAMYRAWLQAGG
PKPAIVAGHSLGEYTALVAAGAIAFRDAVPLVRFRAQAMQTAVPVGEGAMAAILGLDDDTVRAVCAEASVAGVVEAVNFN
APAQVVIAGNKAAVEKACEVAKAKGAKRALPLPVSAPFHSSLLKPASDQLREYLASVDVQVPAIPVINNVDVAVVNEPAA
IKDALVRQAAGAVRWVESVQAMSAQGVTHVIECGPGKVLAGLTKRIDGNLVGASIFDPASLEETLKLVKAG
>Mature_311_residues
MKFAFVFPGQGSQSVGMLNAFADQAVVRETVQEASDALNQDLGKLIAEGPAEDLNLTTNTQPVMLTASYAMYRAWLQAGG
PKPAIVAGHSLGEYTALVAAGAIAFRDAVPLVRFRAQAMQTAVPVGEGAMAAILGLDDDTVRAVCAEASVAGVVEAVNFN
APAQVVIAGNKAAVEKACEVAKAKGAKRALPLPVSAPFHSSLLKPASDQLREYLASVDVQVPAIPVINNVDVAVVNEPAA
IKDALVRQAAGAVRWVESVQAMSAQGVTHVIECGPGKVLAGLTKRIDGNLVGASIFDPASLEETLKLVKAG

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=31.2292358803987, Blast_Score=139, Evalue=3e-33,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=56.6775244299674, Blast_Score=316, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=30.2721088435374, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=29.2096219931272, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24665753, Length=309, Percent_Identity=33.6569579288026, Blast_Score=135, Evalue=5e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32087; Mature: 32087

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADQAVVRETVQEASDALNQDLGKLIAEGPAEDLNLTTNT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCC
QPVMLTASYAMYRAWLQAGGPKPAIVAGHSLGEYTALVAAGAIAFRDAVPLVRFRAQAMQ
CCEEEEHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVPVGEGAMAAILGLDDDTVRAVCAEASVAGVVEAVNFNAPAQVVIAGNKAAVEKACEV
HHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDQLREYLASVDVQVPAIPVINNVDVAVVNEPAA
HHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCHH
IKDALVRQAAGAVRWVESVQAMSAQGVTHVIECGPGKVLAGLTKRIDGNLVGASIFDPAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEECCCCCCCCC
LEETLKLVKAG
HHHHHHHHCCC
>Mature Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADQAVVRETVQEASDALNQDLGKLIAEGPAEDLNLTTNT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCC
QPVMLTASYAMYRAWLQAGGPKPAIVAGHSLGEYTALVAAGAIAFRDAVPLVRFRAQAMQ
CCEEEEHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVPVGEGAMAAILGLDDDTVRAVCAEASVAGVVEAVNFNAPAQVVIAGNKAAVEKACEV
HHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDQLREYLASVDVQVPAIPVINNVDVAVVNEPAA
HHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCHH
IKDALVRQAAGAVRWVESVQAMSAQGVTHVIECGPGKVLAGLTKRIDGNLVGASIFDPAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEECCCCCCCCC
LEETLKLVKAG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]