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The map label for this gene is carA [H]

Identifier: 91784543

GI number: 91784543

Start: 3532838

End: 3534013

Strand: Reverse

Name: carA [H]

Synonym: Bxe_A1256

Alternate gene names: 91784543

Gene position: 3534013-3532838 (Counterclockwise)

Preceding gene: 91784544

Following gene: 91784542

Centisome position: 72.18

GC content: 64.37

Gene sequence:

>1176_bases
GTGTTCCCCAAGGAGTCTCCCGTGTTGCCGTCATTTTCTCCCGCTCTGCTCGCGCTCGCCGACGGCACGGTCTTTCGTGG
TTACTCGATCGGCGCCCCCGGGCATACCATCGGCGAAGTCGTGTTCAACACCGCTATCACCGGCTATCAGGAAATCCTGA
CTGACCCGAGCTACGCGCGCCAGATCGTGACCCTCACGTATCCGCATATCGGCAACGTCGGCGTGAATGCCGAAGACGTC
GAAGCGGCGAAAGTCCATGCCGCCGGCCTGATCATTCGTGATCTGCCGGTTCTCGCGTCGAACTTCCGCATGGAGCGCAC
GCTCCAGCAATACCTGCAGGACGAAGGCGTGGTCGCCATCGCCGGCCTCGATACCCGCATGCTGACCCGCGTTCTGCGCG
ACAAGGGCGCGCAGAACGGCGCGATCCTCGCCGGTTCGGACGATGAAGCTCGCGCCATCGAACTCGCTCGCTCGTTCCCG
GGCCTTTCGGGCATGGACCTCGCGAAGGTCGTGTCGACGAAGGAGTCCTATGAATGGACCCAGACCGAATGGCGGCTGGG
CAGCGGCTACGGCACGCAGAATGCGCCGAAGTACCGCGTGGTGGCGTTCGACTACGGCGTCAAGTACAACATCCTGCGCA
TGCTCGCCGAACGCGGCTGTCACGTCACCGTGCTGCCGGCGGAAGCTTCCGCCGCCGACGCGCTGGCACTCAATCCGGAC
GGCGTCTTCCTGTCGAACGGCCCGGGCGATCCGGAACCGTGCGACTACGCGATCCGCGCCACGAAGGAACTGATCGACCG
CGGCATTCCGACCTTCGGCATCTGCCTCGGCCATCAGATCATGGGCCTCGCGGTCGGCGCCAAAACCATGAAGATGAAGA
CCGGCCACCACGGCGCGAACCATCCGGTGAAAGATCTGGACGACGGCCGCGTGGTGATCACGTCGCAGAACCACGGCTTC
GCGGTCGATGCCGACACGCTGCCCGCCAATGCCCGCGTCACGCATGTTTCGCTGTTCGACGGCACGCTGCAGGGCTTCAC
GCTGACCGACAAGCCGGCGTTCTGCTTCCAGGGTCACCCGGAAGCGTCGCCCGGTCCGCATGACATCGCCTATCTGTTCG
ACCGCTTCACGGCGTTGATGGACACGAAGAAGGCCGGCAAGACCGCAGCGGCATAA

Upstream 100 bases:

>100_bases
CCTTTGCAACGTCAACGGCAGTTCGCGAGCGAGTCTGCGCGCGCATCCCGTGGATGCGTTTCGCTGCGGCTCGCAGTCGG
ATAGACAGGTCGGCAACAGG

Downstream 100 bases:

>100_bases
AGTCCCGGCAGCGCACGGCTCGCGCCGCGCGTGATCGATCAACACGCGGCGCGGAAGCGGCGCACGAGCGACGCACACGC
GGCGAGCCGGACCAGACAGA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MFPKESPVLPSFSPALLALADGTVFRGYSIGAPGHTIGEVVFNTAITGYQEILTDPSYARQIVTLTYPHIGNVGVNAEDV
EAAKVHAAGLIIRDLPVLASNFRMERTLQQYLQDEGVVAIAGLDTRMLTRVLRDKGAQNGAILAGSDDEARAIELARSFP
GLSGMDLAKVVSTKESYEWTQTEWRLGSGYGTQNAPKYRVVAFDYGVKYNILRMLAERGCHVTVLPAEASAADALALNPD
GVFLSNGPGDPEPCDYAIRATKELIDRGIPTFGICLGHQIMGLAVGAKTMKMKTGHHGANHPVKDLDDGRVVITSQNHGF
AVDADTLPANARVTHVSLFDGTLQGFTLTDKPAFCFQGHPEASPGPHDIAYLFDRFTALMDTKKAGKTAAA

Sequences:

>Translated_391_residues
MFPKESPVLPSFSPALLALADGTVFRGYSIGAPGHTIGEVVFNTAITGYQEILTDPSYARQIVTLTYPHIGNVGVNAEDV
EAAKVHAAGLIIRDLPVLASNFRMERTLQQYLQDEGVVAIAGLDTRMLTRVLRDKGAQNGAILAGSDDEARAIELARSFP
GLSGMDLAKVVSTKESYEWTQTEWRLGSGYGTQNAPKYRVVAFDYGVKYNILRMLAERGCHVTVLPAEASAADALALNPD
GVFLSNGPGDPEPCDYAIRATKELIDRGIPTFGICLGHQIMGLAVGAKTMKMKTGHHGANHPVKDLDDGRVVITSQNHGF
AVDADTLPANARVTHVSLFDGTLQGFTLTDKPAFCFQGHPEASPGPHDIAYLFDRFTALMDTKKAGKTAAA
>Mature_391_residues
MFPKESPVLPSFSPALLALADGTVFRGYSIGAPGHTIGEVVFNTAITGYQEILTDPSYARQIVTLTYPHIGNVGVNAEDV
EAAKVHAAGLIIRDLPVLASNFRMERTLQQYLQDEGVVAIAGLDTRMLTRVLRDKGAQNGAILAGSDDEARAIELARSFP
GLSGMDLAKVVSTKESYEWTQTEWRLGSGYGTQNAPKYRVVAFDYGVKYNILRMLAERGCHVTVLPAEASAADALALNPD
GVFLSNGPGDPEPCDYAIRATKELIDRGIPTFGICLGHQIMGLAVGAKTMKMKTGHHGANHPVKDLDDGRVVITSQNHGF
AVDADTLPANARVTHVSLFDGTLQGFTLTDKPAFCFQGHPEASPGPHDIAYLFDRFTALMDTKKAGKTAAA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=386, Percent_Identity=38.3419689119171, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI169790915, Length=383, Percent_Identity=37.8590078328982, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI21361331, Length=383, Percent_Identity=37.8590078328982, Blast_Score=236, Evalue=3e-62,
Organism=Escherichia coli, GI1786215, Length=379, Percent_Identity=64.1160949868074, Blast_Score=502, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI193204318, Length=387, Percent_Identity=38.5012919896641, Blast_Score=241, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6324878, Length=377, Percent_Identity=38.7267904509284, Blast_Score=241, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6322331, Length=394, Percent_Identity=37.3096446700508, Blast_Score=240, Evalue=2e-64,
Organism=Drosophila melanogaster, GI45555749, Length=388, Percent_Identity=40.2061855670103, Blast_Score=241, Evalue=6e-64,
Organism=Drosophila melanogaster, GI24642586, Length=388, Percent_Identity=40.2061855670103, Blast_Score=240, Evalue=1e-63,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41898; Mature: 41898

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPKESPVLPSFSPALLALADGTVFRGYSIGAPGHTIGEVVFNTAITGYQEILTDPSYAR
CCCCCCCCCCCCCCCEEEEECCCEEECEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHC
QIVTLTYPHIGNVGVNAEDVEAAKVHAAGLIIRDLPVLASNFRMERTLQQYLQDEGVVAI
EEEEEECCCCCCCCCCCCCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AGLDTRMLTRVLRDKGAQNGAILAGSDDEARAIELARSFPGLSGMDLAKVVSTKESYEWT
ECCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCC
QTEWRLGSGYGTQNAPKYRVVAFDYGVKYNILRMLAERGCHVTVLPAEASAADALALNPD
CCEEEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCC
GVFLSNGPGDPEPCDYAIRATKELIDRGIPTFGICLGHQIMGLAVGAKTMKMKTGHHGAN
CEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCEEEEECCCCCCC
HPVKDLDDGRVVITSQNHGFAVDADTLPANARVTHVSLFDGTLQGFTLTDKPAFCFQGHP
CCCCCCCCCEEEEEECCCCEEEECCCCCCCCEEEEEEEECCCCCCEEECCCCCEEECCCC
EASPGPHDIAYLFDRFTALMDTKKAGKTAAA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFPKESPVLPSFSPALLALADGTVFRGYSIGAPGHTIGEVVFNTAITGYQEILTDPSYAR
CCCCCCCCCCCCCCCEEEEECCCEEECEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHC
QIVTLTYPHIGNVGVNAEDVEAAKVHAAGLIIRDLPVLASNFRMERTLQQYLQDEGVVAI
EEEEEECCCCCCCCCCCCCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AGLDTRMLTRVLRDKGAQNGAILAGSDDEARAIELARSFPGLSGMDLAKVVSTKESYEWT
ECCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCC
QTEWRLGSGYGTQNAPKYRVVAFDYGVKYNILRMLAERGCHVTVLPAEASAADALALNPD
CCEEEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCC
GVFLSNGPGDPEPCDYAIRATKELIDRGIPTFGICLGHQIMGLAVGAKTMKMKTGHHGAN
CEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCEEEEECCCCCCC
HPVKDLDDGRVVITSQNHGFAVDADTLPANARVTHVSLFDGTLQGFTLTDKPAFCFQGHP
CCCCCCCCCEEEEEECCCCEEEECCCCCCCCEEEEEEEECCCCCCEEECCCCCEEECCCC
EASPGPHDIAYLFDRFTALMDTKKAGKTAAA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]