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The map label for this gene is phoR [H]

Identifier: 91784527

GI number: 91784527

Start: 3514948

End: 3516261

Strand: Reverse

Name: phoR [H]

Synonym: Bxe_A1272

Alternate gene names: 91784527

Gene position: 3516261-3514948 (Counterclockwise)

Preceding gene: 91784528

Following gene: 91784525

Centisome position: 71.82

GC content: 62.1

Gene sequence:

>1314_bases
ATGAACATCATCTGGGCGCGCTCCATCGTGTCGGTCGTGCTGCTGGCTGTTCTGTGCGTGGTGGTCGGCGCACTCGTGAA
CGTCAAGGCAGCGCTCGTCCTCGCGATCGTCATGCTGCTCGCGCAGAGCGTTTTCAGCACTTTCCATAAACAGCGTCTGT
GGCGTCTGCTCGACGCGCCGGTCTACGGCGAAGTGCCGAGCGCTCCCGGCATCTGGGGCGAAATCTACTACCGTTTGCAC
AAGCTCGCGAAGCGCTGGCACGCCCAGGTGCGCCAGGTCGAGCAGCAGCATTCGCGTTTCATCCAAGCGATCCAGGCTTC
GCCGAACGGCGTGGCGATGCTCGACGATCATGACCAGATCGAGTGGTGCAACGCCATCTCCGAACTCCATTTCGGGCTGG
ATGCGAAGCGCGATCTGCGCCAGCACATCACGCATCTGGTGCGTCAGCCCGATTTCGTCCGTTACCTGAATTCGCATCGG
TACGAAGAGATGCTGATCATGCGCGGCATGGGCGACAAGCGTCAGAACGTGCTCTCGGTGCAGGTGTTTCCGTACGGCGA
AAACCGCAAACTGGTGCTTTCGCAGGACATCACCGAACTCGAACGGACCGACGCGATGCGGCGCGACTTCGTCGCGAATG
TTTCGCATGAATTGAAGACGCCGCTCACGGTGCTCTCCGGTTTTCTGGAGACCATGCGCGAGTTGCCGCTGAGCGAAGGC
GAACGTTCACGCTATCTGGAGTTGATGGAGCAGCAGGCTTCGCGCATGCGCCATATCGTCAGCGATCTGCTGGTGCTCGC
CAAGCTGGAGGGCGACAACAAGCCGCCGAGCGATCAGATGATCGACATGCGTGCGGTGTTGCGGCATCTGCGTGACGACG
CGCAGAGCCTGTCGAGCGATCATCACAAGATCGTGTTCGATGCCGACGAAGGGCTCACGGTCACCGGCGTCGAAACGGAA
ATTCTCAGCGCATTCGGCAATCTCGTCACGAACGCGATCCGCTACACGCCGGACGGCGGCGCGATCCGGGTGTCGTGGCA
CGCACAGGGCGGCCATGCGGTGTTTTCCGTGACGGACAGCGGACTGGGTATTCCCGCCGCGGACATTCCGCGGCTGACGG
AGCGCTTCTATCGCGTCGATCGCAGCCGTTCACGCGATACCGGCGGCACGGGCCTCGGACTTGCGATCGTCAAACATGTG
CTCCAGCGTCACGACGCACAGCTCGATGTGAAGAGCGAAGAGGGGCGCGGCAGCACGTTCACGGTGCGCTTTCCGGTGTA
CCGCACCGCGCGTCGGCAACCGGCGCCGGTTTGA

Upstream 100 bases:

>100_bases
CCGGGTACGTCATCTTCGCAACGCTTCTCGTCACCCTTCGCAATGTCAGGCGCCGCGATTCAGATTCCGGTGCATGGGTT
TTTTCTTCGATCGCTAGACC

Downstream 100 bases:

>100_bases
GCGCGAATGCATTGTTAGCATTGATTCGGCATGCTCGCGTAGCCCACCGTGAGTCGATTGACCGCATAATCGACTCAAAT
CATGAGGCGATAGCGACTCC

Product: phosphate sensor signal transduction histidine kinase, PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MNIIWARSIVSVVLLAVLCVVVGALVNVKAALVLAIVMLLAQSVFSTFHKQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKRWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQIEWCNAISELHFGLDAKRDLRQHITHLVRQPDFVRYLNSHR
YEEMLIMRGMGDKRQNVLSVQVFPYGENRKLVLSQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLSEG
ERSRYLELMEQQASRMRHIVSDLLVLAKLEGDNKPPSDQMIDMRAVLRHLRDDAQSLSSDHHKIVFDADEGLTVTGVETE
ILSAFGNLVTNAIRYTPDGGAIRVSWHAQGGHAVFSVTDSGLGIPAADIPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDAQLDVKSEEGRGSTFTVRFPVYRTARRQPAPV

Sequences:

>Translated_437_residues
MNIIWARSIVSVVLLAVLCVVVGALVNVKAALVLAIVMLLAQSVFSTFHKQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKRWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQIEWCNAISELHFGLDAKRDLRQHITHLVRQPDFVRYLNSHR
YEEMLIMRGMGDKRQNVLSVQVFPYGENRKLVLSQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLSEG
ERSRYLELMEQQASRMRHIVSDLLVLAKLEGDNKPPSDQMIDMRAVLRHLRDDAQSLSSDHHKIVFDADEGLTVTGVETE
ILSAFGNLVTNAIRYTPDGGAIRVSWHAQGGHAVFSVTDSGLGIPAADIPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDAQLDVKSEEGRGSTFTVRFPVYRTARRQPAPV
>Mature_437_residues
MNIIWARSIVSVVLLAVLCVVVGALVNVKAALVLAIVMLLAQSVFSTFHKQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKRWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQIEWCNAISELHFGLDAKRDLRQHITHLVRQPDFVRYLNSHR
YEEMLIMRGMGDKRQNVLSVQVFPYGENRKLVLSQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLSEG
ERSRYLELMEQQASRMRHIVSDLLVLAKLEGDNKPPSDQMIDMRAVLRHLRDDAQSLSSDHHKIVFDADEGLTVTGVETE
ILSAFGNLVTNAIRYTPDGGAIRVSWHAQGGHAVFSVTDSGLGIPAADIPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDAQLDVKSEEGRGSTFTVRFPVYRTARRQPAPV

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=421, Percent_Identity=36.104513064133, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI145693157, Length=342, Percent_Identity=28.3625730994152, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788393, Length=267, Percent_Identity=30.7116104868914, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI48994928, Length=375, Percent_Identity=26.9333333333333, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786783, Length=254, Percent_Identity=31.8897637795276, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790436, Length=310, Percent_Identity=27.741935483871, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=29.8387096774194, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=30.0925925925926, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=31.858407079646, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788713, Length=263, Percent_Identity=26.615969581749, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081816, Length=248, Percent_Identity=28.2258064516129, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=25.8928571428571, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=251, Percent_Identity=24.7011952191235, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788549, Length=393, Percent_Identity=22.64631043257, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=26.2222222222222, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790551, Length=238, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=221, Percent_Identity=28.9592760180996, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789403, Length=228, Percent_Identity=28.9473684210526, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49412; Mature: 49412

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIWARSIVSVVLLAVLCVVVGALVNVKAALVLAIVMLLAQSVFSTFHKQRLWRLLDAP
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VYGEVPSAPGIWGEIYYRLHKLAKRWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHH
EWCNAISELHFGLDAKRDLRQHITHLVRQPDFVRYLNSHRYEEMLIMRGMGDKRQNVLSV
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
QVFPYGENRKLVLSQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLSEG
EEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
ERSRYLELMEQQASRMRHIVSDLLVLAKLEGDNKPPSDQMIDMRAVLRHLRDDAQSLSSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
HHKIVFDADEGLTVTGVETEILSAFGNLVTNAIRYTPDGGAIRVSWHAQGGHAVFSVTDS
CCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEEEECC
GLGIPAADIPRLTERFYRVDRSRSRDTGGTGLGLAIVKHVLQRHDAQLDVKSEEGRGSTF
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEE
TVRFPVYRTARRQPAPV
EEEECHHHHCCCCCCCC
>Mature Secondary Structure
MNIIWARSIVSVVLLAVLCVVVGALVNVKAALVLAIVMLLAQSVFSTFHKQRLWRLLDAP
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VYGEVPSAPGIWGEIYYRLHKLAKRWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHH
EWCNAISELHFGLDAKRDLRQHITHLVRQPDFVRYLNSHRYEEMLIMRGMGDKRQNVLSV
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
QVFPYGENRKLVLSQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLSEG
EEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
ERSRYLELMEQQASRMRHIVSDLLVLAKLEGDNKPPSDQMIDMRAVLRHLRDDAQSLSSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
HHKIVFDADEGLTVTGVETEILSAFGNLVTNAIRYTPDGGAIRVSWHAQGGHAVFSVTDS
CCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEEEECC
GLGIPAADIPRLTERFYRVDRSRSRDTGGTGLGLAIVKHVLQRHDAQLDVKSEEGRGSTF
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEE
TVRFPVYRTARRQPAPV
EEEECHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2556368 [H]