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The map label for this gene is ggt [H]

Identifier: 91784491

GI number: 91784491

Start: 3481601

End: 3483355

Strand: Reverse

Name: ggt [H]

Synonym: Bxe_A1308

Alternate gene names: 91784491

Gene position: 3483355-3481601 (Counterclockwise)

Preceding gene: 91784494

Following gene: 91784490

Centisome position: 71.15

GC content: 65.75

Gene sequence:

>1755_bases
ATGTCTGTCCCGACACACGGCGCGCTTCGCGCGCCTTTCACTTCGCTTCGTTTCGCCCGGATCCTGACGGTGTCGGCAAT
GCTTGCCGCGTTCACCGGCGGCGCGCTCGCGCCCACGGCCGCGCTCGCGAAAACGCCGCTGCCCAAGGCCGTATTCGACG
CGTCGGCGGTGGCCGTGCCGGACCGCTACAGCGCGGACACGGCGCAGCAGATTTTCGCGGCCGGCGGCAACGCAGTCGAT
GCCGCGGTCGCGATCGCCTTCACGCTGGCCGTGACCTGTCCGGACGCGGGCAACCTCGGCGGTGGCGGGTTCATGACCAT
GTTCGTGGACGGCAAACCGTACTTCCTCGACTATCGCGAGCGCGCGCCGCAGCAGGCGACCCGCGACATGTACCTCGACG
ACAAGGGCAATCTGCTGCCGGGCATGAGCGCCGTCGGCCATCGCGCGGTAGCCGTGCCGGGAACGGTGGAGGGCATGTGG
GAGGCGCAGCGGCGTTTCGGCAAGCTGAAGTGGAAGCAGGTGCTGGCGCCCGCGATCCGCTATGCGACCGAGGGCTTCCA
GGTCGAGCCGTGGTTGCAGCAGCGCCGCGACGCAGCGGCGAAGAGCTTCGCCGGCAAGACCAATTTCGACGCCTATTTTT
CGGGCCTGAAGGCGGGCGTGACATACCGCCAGCCGGAACTCGCACAGACGCTGTCTCGTATTGCGAGCGACGGCGGGCGC
GAATTCTACGAGGGCCGCACCGCGGACCTGATCGCCCAGCAGATGTACGGCCACGGCCTCGTCACGAAGCAGGACCTGAT
CCAGTACAAGGCCGTGTGGCGCCAGCCGCTCACCGCCGACTGGAACGGCTATCGGGTCGTCACCGCGCCGCCGCCGAGTT
CGGGCGGCATCGGGCTGATCCAGATGCTGAAGATGAAAGCGGATCTGAAGCAGGCGTTCGACGGACTCGACCTCAATTCC
GTGCCGTATATCCATCTGATCGCCCAGATCGAGGACCGCGTGTTCGGTGACCGGCAGCAATACCTGGCCGATCCGGATTC
GTTCAAGGTGCCGGTCGACAAACTGATCGACGACGCCTACCTCGCGCAACGCGCCGACGAAGTCAAACCCGACGAAGTAC
CGGGCGCGGCGCCGGTTACGCCGGGCCTCGGCGACGCCGCACCGGAGAAAGCGCAAACCACCCATTTTTCGGTGGTCGAC
AAGTGGGGTAATGCCGTGTCGAACACGTACACGTTAAATGGAGACTTCGGTTCAGGCGTGGTGGTGGACGGCGGCGGTTT
CCTGTTGAACGATGCGATGGACGACTTCGTCACCAAACCGGCCGGTGCGAGCCCGTCGGGTGCGGGCAGCGCCGAAGTCA
ACACGGTGGCGCCCGGCCGCCGCCCGCTATCCTCGATGACGCCGACCATTCTGTTGAAGGACGACAAGGTGTCGCTCGTG
ATCGGCACGCCAGGCGGCTCGCGCATCCTGACGTCGATTTTCCAGGTGATGACCGACCTGTACGACTTCAATCTGCCGCC
CGCCGACGCGCTCGCCGCAATGCGCTTTCACCATCAGTTGTTGCCGCAGAAGACGATCTATTTCGAGCCGTATCGTCCGA
TCACGGGGGAACTGGCCGAGCAGTTGCAAGCGAAGGGCTACACGCTCGAAGGGCAGTCGTTCAACGGTGACGTGCAGATG
ATCCGCATCGAGGGCGCGACGCCCGAACCGGCGGCGGACCCTCGCGGCGTGGGCGTGGCGCGCGTGATGCATTGA

Upstream 100 bases:

>100_bases
TCGCGTGCCTCCCGTACTCAGGCCGCACAGTCCTTTGCCGCCTTGCGCGAAGTCCCGCGGTTCGTGCAACATGGCGCCCT
CAGTTGCCGGAGTTTCTCGG

Downstream 100 bases:

>100_bases
AGGGGCCGGCGGGGTGGGCCAAAACCGCAGGCCAAAACCGCGGGCGAAAACAATAAACTGCGAACAACGACCAATGACGG
GGAACGCGATGAGCGTACAG

Product: gamma-glutamyltransferase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MSVPTHGALRAPFTSLRFARILTVSAMLAAFTGGALAPTAALAKTPLPKAVFDASAVAVPDRYSADTAQQIFAAGGNAVD
AAVAIAFTLAVTCPDAGNLGGGGFMTMFVDGKPYFLDYRERAPQQATRDMYLDDKGNLLPGMSAVGHRAVAVPGTVEGMW
EAQRRFGKLKWKQVLAPAIRYATEGFQVEPWLQQRRDAAAKSFAGKTNFDAYFSGLKAGVTYRQPELAQTLSRIASDGGR
EFYEGRTADLIAQQMYGHGLVTKQDLIQYKAVWRQPLTADWNGYRVVTAPPPSSGGIGLIQMLKMKADLKQAFDGLDLNS
VPYIHLIAQIEDRVFGDRQQYLADPDSFKVPVDKLIDDAYLAQRADEVKPDEVPGAAPVTPGLGDAAPEKAQTTHFSVVD
KWGNAVSNTYTLNGDFGSGVVVDGGGFLLNDAMDDFVTKPAGASPSGAGSAEVNTVAPGRRPLSSMTPTILLKDDKVSLV
IGTPGGSRILTSIFQVMTDLYDFNLPPADALAAMRFHHQLLPQKTIYFEPYRPITGELAEQLQAKGYTLEGQSFNGDVQM
IRIEGATPEPAADPRGVGVARVMH

Sequences:

>Translated_584_residues
MSVPTHGALRAPFTSLRFARILTVSAMLAAFTGGALAPTAALAKTPLPKAVFDASAVAVPDRYSADTAQQIFAAGGNAVD
AAVAIAFTLAVTCPDAGNLGGGGFMTMFVDGKPYFLDYRERAPQQATRDMYLDDKGNLLPGMSAVGHRAVAVPGTVEGMW
EAQRRFGKLKWKQVLAPAIRYATEGFQVEPWLQQRRDAAAKSFAGKTNFDAYFSGLKAGVTYRQPELAQTLSRIASDGGR
EFYEGRTADLIAQQMYGHGLVTKQDLIQYKAVWRQPLTADWNGYRVVTAPPPSSGGIGLIQMLKMKADLKQAFDGLDLNS
VPYIHLIAQIEDRVFGDRQQYLADPDSFKVPVDKLIDDAYLAQRADEVKPDEVPGAAPVTPGLGDAAPEKAQTTHFSVVD
KWGNAVSNTYTLNGDFGSGVVVDGGGFLLNDAMDDFVTKPAGASPSGAGSAEVNTVAPGRRPLSSMTPTILLKDDKVSLV
IGTPGGSRILTSIFQVMTDLYDFNLPPADALAAMRFHHQLLPQKTIYFEPYRPITGELAEQLQAKGYTLEGQSFNGDVQM
IRIEGATPEPAADPRGVGVARVMH
>Mature_583_residues
SVPTHGALRAPFTSLRFARILTVSAMLAAFTGGALAPTAALAKTPLPKAVFDASAVAVPDRYSADTAQQIFAAGGNAVDA
AVAIAFTLAVTCPDAGNLGGGGFMTMFVDGKPYFLDYRERAPQQATRDMYLDDKGNLLPGMSAVGHRAVAVPGTVEGMWE
AQRRFGKLKWKQVLAPAIRYATEGFQVEPWLQQRRDAAAKSFAGKTNFDAYFSGLKAGVTYRQPELAQTLSRIASDGGRE
FYEGRTADLIAQQMYGHGLVTKQDLIQYKAVWRQPLTADWNGYRVVTAPPPSSGGIGLIQMLKMKADLKQAFDGLDLNSV
PYIHLIAQIEDRVFGDRQQYLADPDSFKVPVDKLIDDAYLAQRADEVKPDEVPGAAPVTPGLGDAAPEKAQTTHFSVVDK
WGNAVSNTYTLNGDFGSGVVVDGGGFLLNDAMDDFVTKPAGASPSGAGSAEVNTVAPGRRPLSSMTPTILLKDDKVSLVI
GTPGGSRILTSIFQVMTDLYDFNLPPADALAAMRFHHQLLPQKTIYFEPYRPITGELAEQLQAKGYTLEGQSFNGDVQMI
RIEGATPEPAADPRGVGVARVMH

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=489, Percent_Identity=28.8343558282209, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI73915090, Length=489, Percent_Identity=28.8343558282209, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI73915096, Length=489, Percent_Identity=28.8343558282209, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI73915094, Length=489, Percent_Identity=28.8343558282209, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI109148539, Length=520, Percent_Identity=28.8461538461538, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI113429324, Length=492, Percent_Identity=27.8455284552846, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI153266901, Length=549, Percent_Identity=27.5045537340619, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI153266885, Length=548, Percent_Identity=27.007299270073, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI113429326, Length=497, Percent_Identity=27.1629778672032, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI153266907, Length=546, Percent_Identity=25.8241758241758, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI30581157, Length=186, Percent_Identity=36.5591397849462, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI30581155, Length=186, Percent_Identity=36.5591397849462, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI218505805, Length=137, Percent_Identity=38.6861313868613, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1789856, Length=531, Percent_Identity=42.1845574387947, Blast_Score=367, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17542894, Length=517, Percent_Identity=31.5280464216634, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI72000294, Length=499, Percent_Identity=29.6593186372746, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI212646519, Length=499, Percent_Identity=29.6593186372746, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17506189, Length=550, Percent_Identity=29.4545454545455, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI193208245, Length=505, Percent_Identity=29.1089108910891, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI193208247, Length=505, Percent_Identity=29.1089108910891, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17564448, Length=443, Percent_Identity=25.7336343115124, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI72001495, Length=230, Percent_Identity=25.2173913043478, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI72001497, Length=230, Percent_Identity=25.2173913043478, Blast_Score=92, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323330, Length=555, Percent_Identity=28.4684684684685, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI18859893, Length=537, Percent_Identity=29.4227188081937, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI161077496, Length=539, Percent_Identity=30.0556586270872, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI161077880, Length=519, Percent_Identity=27.1676300578035, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI161077878, Length=517, Percent_Identity=26.4990328820116, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45551474, Length=521, Percent_Identity=26.8714011516315, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24642670, Length=521, Percent_Identity=26.8714011516315, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24642666, Length=521, Percent_Identity=26.8714011516315, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI18859741, Length=541, Percent_Identity=26.2476894639556, Blast_Score=135, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 62654; Mature: 62523

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPTHGALRAPFTSLRFARILTVSAMLAAFTGGALAPTAALAKTPLPKAVFDASAVAVP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHCCCCEECC
DRYSADTAQQIFAAGGNAVDAAVAIAFTLAVTCPDAGNLGGGGFMTMFVDGKPYFLDYRE
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCEEECHHH
RAPQQATRDMYLDDKGNLLPGMSAVGHRAVAVPGTVEGMWEAQRRFGKLKWKQVLAPAIR
CCHHHHHHCCEECCCCCCCCCCHHHCCCEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHH
YATEGFQVEPWLQQRRDAAAKSFAGKTNFDAYFSGLKAGVTYRQPELAQTLSRIASDGGR
HHCCCCEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCH
EFYEGRTADLIAQQMYGHGLVTKQDLIQYKAVWRQPLTADWNGYRVVTAPPPSSGGIGLI
HHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHH
QMLKMKADLKQAFDGLDLNSVPYIHLIAQIEDRVFGDRQQYLADPDSFKVPVDKLIDDAY
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHH
LAQRADEVKPDEVPGAAPVTPGLGDAAPEKAQTTHFSVVDKWGNAVSNTYTLNGDFGSGV
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCEEEECCCCCCCE
VVDGGGFLLNDAMDDFVTKPAGASPSGAGSAEVNTVAPGRRPLSSMTPTILLKDDKVSLV
EECCCCEEEHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHCCCEEEEECCCEEEE
IGTPGGSRILTSIFQVMTDLYDFNLPPADALAAMRFHHQLLPQKTIYFEPYRPITGELAE
EECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH
QLQAKGYTLEGQSFNGDVQMIRIEGATPEPAADPRGVGVARVMH
HHHHCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure 
SVPTHGALRAPFTSLRFARILTVSAMLAAFTGGALAPTAALAKTPLPKAVFDASAVAVP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHCCCCEECC
DRYSADTAQQIFAAGGNAVDAAVAIAFTLAVTCPDAGNLGGGGFMTMFVDGKPYFLDYRE
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCEEECHHH
RAPQQATRDMYLDDKGNLLPGMSAVGHRAVAVPGTVEGMWEAQRRFGKLKWKQVLAPAIR
CCHHHHHHCCEECCCCCCCCCCHHHCCCEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHH
YATEGFQVEPWLQQRRDAAAKSFAGKTNFDAYFSGLKAGVTYRQPELAQTLSRIASDGGR
HHCCCCEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCH
EFYEGRTADLIAQQMYGHGLVTKQDLIQYKAVWRQPLTADWNGYRVVTAPPPSSGGIGLI
HHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHH
QMLKMKADLKQAFDGLDLNSVPYIHLIAQIEDRVFGDRQQYLADPDSFKVPVDKLIDDAY
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHH
LAQRADEVKPDEVPGAAPVTPGLGDAAPEKAQTTHFSVVDKWGNAVSNTYTLNGDFGSGV
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCEEEECCCCCCCE
VVDGGGFLLNDAMDDFVTKPAGASPSGAGSAEVNTVAPGRRPLSSMTPTILLKDDKVSLV
EECCCCEEEHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHCCCEEEEECCCEEEE
IGTPGGSRILTSIFQVMTDLYDFNLPPADALAAMRFHHQLLPQKTIYFEPYRPITGELAE
EECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH
QLQAKGYTLEGQSFNGDVQMIRIEGATPEPAADPRGVGVARVMH
HHHHCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]