Click here to switch to the map view.

The map label for this gene is ltaE [H]

Identifier: 91784485

GI number: 91784485

Start: 3472994

End: 3474025

Strand: Reverse

Name: ltaE [H]

Synonym: Bxe_A1314

Alternate gene names: 91784485

Gene position: 3474025-3472994 (Counterclockwise)

Preceding gene: 91784486

Following gene: 91784484

Centisome position: 70.96

GC content: 64.34

Gene sequence:

>1032_bases
ATGCAACATTTCGCGTCCGACAACTACGCCGGCATCTGTCCCGAAGCGCTCGAAGCGCTGATCGCCGCCAACAACAGCGG
CCACGAACCGGCCTACGGCGACGACTCCTGGACCAACCAGGTCTGCGACCGTCTGCGCGAGCTGTTCCAGACCGACTGCG
AAGTGTTCTTCGTATTCAACGGCACGGCCGCCAATTCGCTGGCGCTCGCGTCGCTGTGCCAGTCGTATCACTCGGTGATC
TGCCACGATCTCGCGCACATCGAAACCGACGAATGCGGCGGACCCGAATTCTTCTCGGGCGGCTCGAAACTGCTGACGGC
GCCGGGCGTCGGCGGCAAACTCACACCGGATGCGATCGAAGCCATCGTCACACGCCGCGCCGACATCCATTACCCGAAGC
CGAAAGTCGTCACGCTGACCCAGTCGACGGAAGTCGGCACCGTGTACAGCGTCGAAGAAGTGCGCGCGATCGCGGCGATC
GCCAAGCGGCGTCACCTGAAAGTGCATATGGACGGCGCGCGTTTCGCCAACGCGGTCGCCGCGCTCGACGTGCATCCGTC
GGAGATCACGTGGCGCGCGGGCGTGGACGTGCTGTGTTTCGGCGGCACCAAGAACGGCTTGCCGGTCGGTGAAGCGGTGG
TGTTCTTCGACCGCGCGCTCGCCGCCGATTTCGCCTACCGCCTGAAACAGGCCGGCCAGCTGGCCTCGAAGATGCGCTTC
ATTTCCGCGCCCTGGCTCGGTCTGCTCGATAACGACGTGTGGTTGCGCAACGCGCGTCATGCGAACGCAATGGCGCAATT
GCTGCAAACGCGGTTGCAGGAAATTCCGGGCGTGAGCATCATGTTTCCCAGAGAATCGAACGCGGTCTTCGCGCAATTGC
CCGCGCAAGCCGCCAGGGCAATGCGTGCGCGCGGCTGGAAGTTCTACGAATTCATCGGCGCGGGCGGTTGCCGGCTGATG
TGCGCGTGGGATACGCAGCCGGAAACGGTCGAACGGTTCGCCGCCGAGGTGCGGGAGTTGTGCGCGGCGTGA

Upstream 100 bases:

>100_bases
CCGGCGGCCCGCCCCCAAAAAAACAAATAACCGAACGGCGCACTAAAATGACCGCTTTCCCGTCATCTCAGCGCGCCTGT
CGCCGGGCGCGCCGCCAGCC

Downstream 100 bases:

>100_bases
GATCGCAAACCGCACGCTGCACACCCGCAGCCGTGCGCGAACAGGCAGGATCACACAAAACAAACGGGACATCCCTCTCA
CCATGACCGAGTACCGATTC

Product: L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MQHFASDNYAGICPEALEALIAANNSGHEPAYGDDSWTNQVCDRLRELFQTDCEVFFVFNGTAANSLALASLCQSYHSVI
CHDLAHIETDECGGPEFFSGGSKLLTAPGVGGKLTPDAIEAIVTRRADIHYPKPKVVTLTQSTEVGTVYSVEEVRAIAAI
AKRRHLKVHMDGARFANAVAALDVHPSEITWRAGVDVLCFGGTKNGLPVGEAVVFFDRALAADFAYRLKQAGQLASKMRF
ISAPWLGLLDNDVWLRNARHANAMAQLLQTRLQEIPGVSIMFPRESNAVFAQLPAQAARAMRARGWKFYEFIGAGGCRLM
CAWDTQPETVERFAAEVRELCAA

Sequences:

>Translated_343_residues
MQHFASDNYAGICPEALEALIAANNSGHEPAYGDDSWTNQVCDRLRELFQTDCEVFFVFNGTAANSLALASLCQSYHSVI
CHDLAHIETDECGGPEFFSGGSKLLTAPGVGGKLTPDAIEAIVTRRADIHYPKPKVVTLTQSTEVGTVYSVEEVRAIAAI
AKRRHLKVHMDGARFANAVAALDVHPSEITWRAGVDVLCFGGTKNGLPVGEAVVFFDRALAADFAYRLKQAGQLASKMRF
ISAPWLGLLDNDVWLRNARHANAMAQLLQTRLQEIPGVSIMFPRESNAVFAQLPAQAARAMRARGWKFYEFIGAGGCRLM
CAWDTQPETVERFAAEVRELCAA
>Mature_343_residues
MQHFASDNYAGICPEALEALIAANNSGHEPAYGDDSWTNQVCDRLRELFQTDCEVFFVFNGTAANSLALASLCQSYHSVI
CHDLAHIETDECGGPEFFSGGSKLLTAPGVGGKLTPDAIEAIVTRRADIHYPKPKVVTLTQSTEVGTVYSVEEVRAIAAI
AKRRHLKVHMDGARFANAVAALDVHPSEITWRAGVDVLCFGGTKNGLPVGEAVVFFDRALAADFAYRLKQAGQLASKMRF
ISAPWLGLLDNDVWLRNARHANAMAQLLQTRLQEIPGVSIMFPRESNAVFAQLPAQAARAMRARGWKFYEFIGAGGCRLM
CAWDTQPETVERFAAEVRELCAA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=349, Percent_Identity=27.5071633237822, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193206522, Length=197, Percent_Identity=34.5177664974619, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193206520, Length=197, Percent_Identity=34.5177664974619, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193206524, Length=197, Percent_Identity=34.5177664974619, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320789, Length=340, Percent_Identity=25, Blast_Score=76, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37435; Mature: 37435

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHFASDNYAGICPEALEALIAANNSGHEPAYGDDSWTNQVCDRLRELFQTDCEVFFVFN
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEC
GTAANSLALASLCQSYHSVICHDLAHIETDECGGPEFFSGGSKLLTAPGVGGKLTPDAIE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEECCCCCCCCCHHHHH
AIVTRRADIHYPKPKVVTLTQSTEVGTVYSVEEVRAIAAIAKRRHLKVHMDGARFANAVA
HHHHHHCCCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHCCEEEEECCHHHHHHHH
ALDVHPSEITWRAGVDVLCFGGTKNGLPVGEAVVFFDRALAADFAYRLKQAGQLASKMRF
EEECCCCCEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAPWLGLLDNDVWLRNARHANAMAQLLQTRLQEIPGVSIMFPRESNAVFAQLPAQAARA
HCCCCHHHCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEECCHHHHHH
MRARGWKFYEFIGAGGCRLMCAWDTQPETVERFAAEVRELCAA
HHHCCCEEEHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQHFASDNYAGICPEALEALIAANNSGHEPAYGDDSWTNQVCDRLRELFQTDCEVFFVFN
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEC
GTAANSLALASLCQSYHSVICHDLAHIETDECGGPEFFSGGSKLLTAPGVGGKLTPDAIE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEECCCCCCCCCHHHHH
AIVTRRADIHYPKPKVVTLTQSTEVGTVYSVEEVRAIAAIAKRRHLKVHMDGARFANAVA
HHHHHHCCCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHCCEEEEECCHHHHHHHH
ALDVHPSEITWRAGVDVLCFGGTKNGLPVGEAVVFFDRALAADFAYRLKQAGQLASKMRF
EEECCCCCEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAPWLGLLDNDVWLRNARHANAMAQLLQTRLQEIPGVSIMFPRESNAVFAQLPAQAARA
HCCCCHHHCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEECCHHHHHH
MRARGWKFYEFIGAGGCRLMCAWDTQPETVERFAAEVRELCAA
HHHCCCEEEHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]