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The map label for this gene is dhaT [H]

Identifier: 91784483

GI number: 91784483

Start: 3471176

End: 3472324

Strand: Reverse

Name: dhaT [H]

Synonym: Bxe_A1316

Alternate gene names: 91784483

Gene position: 3472324-3471176 (Counterclockwise)

Preceding gene: 91784484

Following gene: 91784482

Centisome position: 70.92

GC content: 66.49

Gene sequence:

>1149_bases
ATGGCCTATATTTTCTATCTGACCCATATCCATCTCGGCTACGACGCGCTGTCGCAGCTATCGTCCGAATGCGGACGTGT
CGGCATCAAGCGGCCTTTGATCATCACCGACAAGGGCGTCGTCGCGGCCGGCCTCGCGCAGCGCGCGCTAGACGCGCTGA
AATCCGGCGCCGTGCCGGTCTTCGACGACACGCCTTCGAACCCGACCGAGGCGATGGTGCTCGCCGCCGCCCAGGCGTAC
CGCGGCGAAGGCTGCGACGGTCTGATCGCGGTGGGCGGCGGGTCGTCGATCGATCTGGCCAAGGGCGTAGCGATCGCGGC
CACGCATGCCGGTGCGCTGACGCAGTACGCGACCATCGAAGGCGGCAGCCCGAAGATCACGGCCGCGGCCGCGCCGCTGA
TCGCCGTTCCCACCACGGCGGGCACGGGCAGCGAAGTCGCTCGCGGCGCGATCGTGATCCTGAACGACGGCCGCAAGCTC
GGCTTTCATTCGTGGCACCTGCTGCCCAAGTCGGCGTTATGCGATCCGGCGCTCACGCTCGGCCTGCCGCCGGGTTTGAC
GGCGGCCACCGGCATGGACGCAATCGCGCACTGCATCGAGACTTTTCTCGCGCCGGCCTTCAATCCGCCCGCGGACGGCA
TCGCGCTGGACGGGTTGGAGCGCGCGTGGGCCAACATCGAACGCGCGACGGCGGACGGCAGCGATCGCGACGCGCGTCTG
AACATGATGAGCGCCTCGATGCAAGGCGCGATGGCGTTCCAGAAAGGGCTTGGCTGTGTGCATTCGCTGTCGCATCCGCT
GGGCGGCTTGACGGTGAACGGCAAAACGTCGCTGCATCACGGCACGCTGAACGCGGTTGTGTTGCCCGCGGTGCTGCGCT
TCAACGAGACAGCGGACAGCGTGGTGGCTGAGCGCCGTTATGCAAGAATGCGCCGCGTAATGACTTTGCCGGACAACGCG
GATCTCGCGCAGGCACTGTTCGACATGACCGCGCGGCTCGGCTTGCCGACCGGTCTCAGGCAGATGGGCGTCGACGAAAG
CATGTTCGACAAGGTGATCCAGGGCGCGCTCGCCGATCATTGTCACCGCACGAATCCACGCGAAGCCACCGCCGACGACT
ACCGCCGCATGCTGACCGAATCGCTCTGA

Upstream 100 bases:

>100_bases
GGCGCGGCTTGCCGTTCGAGTTTGTCGAGAGGCCGGGACAGTAGCAGACCAGACAGACCAATCAGCAGGGCGACGAGCTT
GCGCTCGGGAGGAGCACGGC

Downstream 100 bases:

>100_bases
AGCAAGCGAGAGCCGCGCAACGCGCACGACAACTTCAAACGGACTCACGCCAGGCATGAACAAACCCGCACCCGCTTCGC
GCACCGCTTATCCGCATTTC

Product: putative iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: 1,3-propanediol oxidoreductase; 3-hydroxypropionaldehyde reductase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MAYIFYLTHIHLGYDALSQLSSECGRVGIKRPLIITDKGVVAAGLAQRALDALKSGAVPVFDDTPSNPTEAMVLAAAQAY
RGEGCDGLIAVGGGSSIDLAKGVAIAATHAGALTQYATIEGGSPKITAAAAPLIAVPTTAGTGSEVARGAIVILNDGRKL
GFHSWHLLPKSALCDPALTLGLPPGLTAATGMDAIAHCIETFLAPAFNPPADGIALDGLERAWANIERATADGSDRDARL
NMMSASMQGAMAFQKGLGCVHSLSHPLGGLTVNGKTSLHHGTLNAVVLPAVLRFNETADSVVAERRYARMRRVMTLPDNA
DLAQALFDMTARLGLPTGLRQMGVDESMFDKVIQGALADHCHRTNPREATADDYRRMLTESL

Sequences:

>Translated_382_residues
MAYIFYLTHIHLGYDALSQLSSECGRVGIKRPLIITDKGVVAAGLAQRALDALKSGAVPVFDDTPSNPTEAMVLAAAQAY
RGEGCDGLIAVGGGSSIDLAKGVAIAATHAGALTQYATIEGGSPKITAAAAPLIAVPTTAGTGSEVARGAIVILNDGRKL
GFHSWHLLPKSALCDPALTLGLPPGLTAATGMDAIAHCIETFLAPAFNPPADGIALDGLERAWANIERATADGSDRDARL
NMMSASMQGAMAFQKGLGCVHSLSHPLGGLTVNGKTSLHHGTLNAVVLPAVLRFNETADSVVAERRYARMRRVMTLPDNA
DLAQALFDMTARLGLPTGLRQMGVDESMFDKVIQGALADHCHRTNPREATADDYRRMLTESL
>Mature_381_residues
AYIFYLTHIHLGYDALSQLSSECGRVGIKRPLIITDKGVVAAGLAQRALDALKSGAVPVFDDTPSNPTEAMVLAAAQAYR
GEGCDGLIAVGGGSSIDLAKGVAIAATHAGALTQYATIEGGSPKITAAAAPLIAVPTTAGTGSEVARGAIVILNDGRKLG
FHSWHLLPKSALCDPALTLGLPPGLTAATGMDAIAHCIETFLAPAFNPPADGIALDGLERAWANIERATADGSDRDARLN
MMSASMQGAMAFQKGLGCVHSLSHPLGGLTVNGKTSLHHGTLNAVVLPAVLRFNETADSVVAERRYARMRRVMTLPDNAD
LAQALFDMTARLGLPTGLRQMGVDESMFDKVIQGALADHCHRTNPREATADDYRRMLTESL

Specific function: Most active with substrates containing two primary alcohol groups separated by one or two carbon atoms. In the physiological direction, 3-hydroxypropionaldehyde is the preferred substrate [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=399, Percent_Identity=27.0676691729323, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI48994951, Length=384, Percent_Identity=34.1145833333333, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789163, Length=374, Percent_Identity=32.0855614973262, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI87082107, Length=366, Percent_Identity=33.0601092896175, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787493, Length=390, Percent_Identity=30.5128205128205, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789386, Length=321, Percent_Identity=30.2180685358255, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17537053, Length=387, Percent_Identity=28.1653746770026, Blast_Score=108, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6321181, Length=376, Percent_Identity=34.0425531914894, Blast_Score=196, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24657991, Length=425, Percent_Identity=28, Blast_Score=111, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.202 [H]

Molecular weight: Translated: 39913; Mature: 39782

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYIFYLTHIHLGYDALSQLSSECGRVGIKRPLIITDKGVVAAGLAQRALDALKSGAVPV
CEEEEEEEHHHHCHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
FDDTPSNPTEAMVLAAAQAYRGEGCDGLIAVGGGSSIDLAKGVAIAATHAGALTQYATIE
ECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCEEEEEECCCHHHEEEEEC
GGSPKITAAAAPLIAVPTTAGTGSEVARGAIVILNDGRKLGFHSWHLLPKSALCDPALTL
CCCCEEEEECCCEEEECCCCCCCHHHHCCEEEEEECCCEECCCCEECCCHHHHCCCHHHC
GLPPGLTAATGMDAIAHCIETFLAPAFNPPADGIALDGLERAWANIERATADGSDRDARL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCHHH
NMMSASMQGAMAFQKGLGCVHSLSHPLGGLTVNGKTSLHHGTLNAVVLPAVLRFNETADS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCHHHH
VVAERRYARMRRVMTLPDNADLAQALFDMTARLGLPTGLRQMGVDESMFDKVIQGALADH
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHH
CHRTNPREATADDYRRMLTESL
HHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AYIFYLTHIHLGYDALSQLSSECGRVGIKRPLIITDKGVVAAGLAQRALDALKSGAVPV
EEEEEEEHHHHCHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
FDDTPSNPTEAMVLAAAQAYRGEGCDGLIAVGGGSSIDLAKGVAIAATHAGALTQYATIE
ECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCEEEEEECCCHHHEEEEEC
GGSPKITAAAAPLIAVPTTAGTGSEVARGAIVILNDGRKLGFHSWHLLPKSALCDPALTL
CCCCEEEEECCCEEEECCCCCCCHHHHCCEEEEEECCCEECCCCEECCCHHHHCCCHHHC
GLPPGLTAATGMDAIAHCIETFLAPAFNPPADGIALDGLERAWANIERATADGSDRDARL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCHHH
NMMSASMQGAMAFQKGLGCVHSLSHPLGGLTVNGKTSLHHGTLNAVVLPAVLRFNETADS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCHHHH
VVAERRYARMRRVMTLPDNADLAQALFDMTARLGLPTGLRQMGVDESMFDKVIQGALADH
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHH
CHRTNPREATADDYRRMLTESL
HHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721705 [H]