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The map label for this gene is lpsI [H]

Identifier: 91784433

GI number: 91784433

Start: 3407786

End: 3408490

Strand: Reverse

Name: lpsI [H]

Synonym: Bxe_A1366

Alternate gene names: 91784433

Gene position: 3408490-3407786 (Counterclockwise)

Preceding gene: 91784435

Following gene: 91784432

Centisome position: 69.62

GC content: 62.13

Gene sequence:

>705_bases
ATGAACAAGGTCTATCCAGGCGCCGCCGAGGCGCTGAAAGACATCGTCAAGGACGGGCAGACGTTTGCCGTCGGCGGCTT
CGGGCTGTGCGGCATTCCCGAGGCGCTGATCGGCGCATTGCGCGATTCGAACGTGCAGGGCATCACCTGCATCAGCAACA
ACGCGGGCGTCGACGGTTTCGGCCTCGGTCTGCTGCTCGAAACGCGTCAGGTCAAGAAGATGATCTCGTCGTATGTCGGC
GAGAACAAGGAGTTCGAGCGCCAGTATCTGGCCGGCGAACTCGAGCTCGAATTCACGCCGCAAGGCACGCTCGCCGAGAA
GCTGCGCGCGGGCGGCTCGGGCATTCCGGCTTTCTTCACCAATACCGGCTACGGCACGCTGATCGCCGAAGGCAAGGAAA
CCCGCCAGTTCGGCGAAAACCATTACGTGCTCGAACACTCGCTGACGGCCGACGTCGCGCTGGTCAAGGCGTGGAAGGCC
GACAAGTCGGGCAACCTGATCTACCGCCGCACCGCGCGCAACTTCAACCCCATGTGCGCGATGGCCGGCAAGATCACCGT
CGCGGAAGTCGAAGAAATCGTCGAAGTGGGCGAACTCGATCCGGACGCGATCCATACGCCAGGCATCTTCGTGCAGCGCA
TCGTGCTCAATGCGCATCCGGAAAAACGCATCGAACAACGCGTCGTCCGCGCGAAAGGAGACTGA

Upstream 100 bases:

>100_bases
ATGACGTGTCGGGCTCGAGCCCGCAAAACGCCATACGAGCCGCAACGATCCGGCGGCCCGCGTTCGGGTTTCGGATTTCC
ATAAAGGAAGGGACATACTG

Downstream 100 bases:

>100_bases
TCATGGCATGGACTCGTGACGAAATGGCCGCGCGCGCGGCGAAGGAATTGCAGGACGGCTTTTATGTGAACCTCGGCATC
GGCCTGCCTACGCTGGTAGC

Product: 3-oxoacid CoA-transferase

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNKVYPGAAEALKDIVKDGQTFAVGGFGLCGIPEALIGALRDSNVQGITCISNNAGVDGFGLGLLLETRQVKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFTNTGYGTLIAEGKETRQFGENHYVLEHSLTADVALVKAWKA
DKSGNLIYRRTARNFNPMCAMAGKITVAEVEEIVEVGELDPDAIHTPGIFVQRIVLNAHPEKRIEQRVVRAKGD

Sequences:

>Translated_234_residues
MNKVYPGAAEALKDIVKDGQTFAVGGFGLCGIPEALIGALRDSNVQGITCISNNAGVDGFGLGLLLETRQVKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFTNTGYGTLIAEGKETRQFGENHYVLEHSLTADVALVKAWKA
DKSGNLIYRRTARNFNPMCAMAGKITVAEVEEIVEVGELDPDAIHTPGIFVQRIVLNAHPEKRIEQRVVRAKGD
>Mature_234_residues
MNKVYPGAAEALKDIVKDGQTFAVGGFGLCGIPEALIGALRDSNVQGITCISNNAGVDGFGLGLLLETRQVKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFTNTGYGTLIAEGKETRQFGENHYVLEHSLTADVALVKAWKA
DKSGNLIYRRTARNFNPMCAMAGKITVAEVEEIVEVGELDPDAIHTPGIFVQRIVLNAHPEKRIEQRVVRAKGD

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=252, Percent_Identity=56.7460317460317, Blast_Score=289, Evalue=1e-78,
Organism=Homo sapiens, GI11545841, Length=251, Percent_Identity=52.5896414342629, Blast_Score=244, Evalue=4e-65,
Organism=Escherichia coli, GI1788551, Length=201, Percent_Identity=43.2835820895522, Blast_Score=179, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17531517, Length=252, Percent_Identity=55.1587301587302, Blast_Score=266, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24655794, Length=250, Percent_Identity=52.8, Blast_Score=249, Evalue=7e-67,
Organism=Drosophila melanogaster, GI21358325, Length=250, Percent_Identity=52.8, Blast_Score=249, Evalue=8e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25355; Mature: 25355

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVYPGAAEALKDIVKDGQTFAVGGFGLCGIPEALIGALRDSNVQGITCISNNAGVDGF
CCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
GLGLLLETRQVKKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCEEEE
NTGYGTLIAEGKETRQFGENHYVLEHSLTADVALVKAWKADKSGNLIYRRTARNFNPMCA
CCCCEEEEECCHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGKITVAEVEEIVEVGELDPDAIHTPGIFVQRIVLNAHPEKRIEQRVVRAKGD
HCCCEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKVYPGAAEALKDIVKDGQTFAVGGFGLCGIPEALIGALRDSNVQGITCISNNAGVDGF
CCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
GLGLLLETRQVKKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCEEEE
NTGYGTLIAEGKETRQFGENHYVLEHSLTADVALVKAWKADKSGNLIYRRTARNFNPMCA
CCCCEEEEECCHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGKITVAEVEEIVEVGELDPDAIHTPGIFVQRIVLNAHPEKRIEQRVVRAKGD
HCCCEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]