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The map label for this gene is siaT [H]

Identifier: 91784323

GI number: 91784323

Start: 3284537

End: 3285823

Strand: Reverse

Name: siaT [H]

Synonym: Bxe_A1477

Alternate gene names: 91784323

Gene position: 3285823-3284537 (Counterclockwise)

Preceding gene: 91784324

Following gene: 91784322

Centisome position: 67.11

GC content: 62.63

Gene sequence:

>1287_bases
ATGCCCGCCTTCCTGTTCGTGCTTTTCATCGGCCTGATGGCCCTCGGCGTGCCGGTGACGATGGCGATCGGCGCGTCGGC
GCTCTCCGTATTCGCGATGAGCGGCTTCACCGATGCGCTTTATGTGTTGCCGCAACAGATGCTCGAAGGCATCGACAGCC
CGTCGATGATGTCGATTCCGTTTTTCATTCTCGCGGGCAACCTGATGAACGCGGTGGGCGTGACCGACCGGATCTTCTCG
CTGGCTCTCGTGCTCGTGGGGCGTTTTCGGGGCGGCCTTGCGCAGGTCAGCGTGATTGCGGCCGCCATCTTCTCCGGCAT
TTCGGGCTCGGCGCTCGCCGACATCGCGGGACTCGGGGCGATCGAAGTGAAAGCCATGCGCGAGCGCGGCTACCCTGCTG
AATTCGCCGCTGCCGTATCCGTCGCGTCGTCGGTCATGGCGCCGATCATGCCGCCGTCGATTGCGTTCATTGTGTACGCG
TCAATGGCCAATGCGTCGGTGGCCCGCATGTTCATGGCGGGCATCGTGCCCGCCACGTTGCTGGCGATTTCACTGATGGT
GTGCAATCGCATCATTGCCGGCAGGCGGGGTTATCCGCGAGAGGAAGCCATGCCGTTCGACCTCGCGGTGCGTACCGTCA
TCGCCGGCCTGCCCGCGCTCGGCGCACCGGCGATCATTCTGATCGGCACGATGGGCGGCTATACGACGGTTGGCGAAGCG
GGCATTCTCGCTTCGGTCTATTCGATGCTGCTCGGTTTCGCGTACCGCTCCATCAACCTGAAGAAAGTCTGGCAAGCGAT
CAACGACACGGTTTCTGTCACGGCCCTGATCATGGTGATCATCGGGTTCTCGCATTTCATGAGCTGGGTGCTGGCCATCC
AGCAGGCGCCGCAGCATCTGGCAGCGCTCGTGCTGACGCTCACGCAATCGCCGACGGTCCTGATGCTGCTGCTCGTCGCA
TTCCTGCTCTTCATCGGCTGCTTTATCGAAAGCGCGCCGGCCAAGCTGATTCTCGTGCCGGTGCTGCTGCCGGTAATCGA
CCAGTTCGGCATCGACCGCGTGCAGTTCGGCGTGGTGATGACGCTCGCTCTCGCACTCGGCATCGCGCATCCGCCAATGG
GTGTAGGCCTCTTTGTCGTGACGCGCGTGTCCAATGTGTCGCTGGAACGCGTCACGATGGCAGTGCTGCCTCTGCTGATT
CCGCTGCTCGTCGTCCTGATCGTCGTGGCGCTGATTCCTTCGCTATCGACGTGGCTGCCTGATCTGGTGATGGGCGCGCC
TTCCTGA

Upstream 100 bases:

>100_bases
TCGTCGGGCTGATCGCGCTCGATGCGTCGCTCGATCTCTATCATCTCGCTGCGCGGCGCCTGTCGCCGGGCGCGGCAATC
GCCTGGCAGGAGTGAACGCA

Downstream 100 bases:

>100_bases
TCCTGTTGTCTGCGCGCAGGCGAGGGCGCGAATAGTCGGAAAAACGTATTACGCATTTTTTTAGCCAGACCCGCAAAGCC
AACGTCGTCACGGCAGGCTT

Product: TRAP C4-dicarboxylate transporter, DctM (12TM)subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MPAFLFVLFIGLMALGVPVTMAIGASALSVFAMSGFTDALYVLPQQMLEGIDSPSMMSIPFFILAGNLMNAVGVTDRIFS
LALVLVGRFRGGLAQVSVIAAAIFSGISGSALADIAGLGAIEVKAMRERGYPAEFAAAVSVASSVMAPIMPPSIAFIVYA
SMANASVARMFMAGIVPATLLAISLMVCNRIIAGRRGYPREEAMPFDLAVRTVIAGLPALGAPAIILIGTMGGYTTVGEA
GILASVYSMLLGFAYRSINLKKVWQAINDTVSVTALIMVIIGFSHFMSWVLAIQQAPQHLAALVLTLTQSPTVLMLLLVA
FLLFIGCFIESAPAKLILVPVLLPVIDQFGIDRVQFGVVMTLALALGIAHPPMGVGLFVVTRVSNVSLERVTMAVLPLLI
PLLVVLIVVALIPSLSTWLPDLVMGAPS

Sequences:

>Translated_428_residues
MPAFLFVLFIGLMALGVPVTMAIGASALSVFAMSGFTDALYVLPQQMLEGIDSPSMMSIPFFILAGNLMNAVGVTDRIFS
LALVLVGRFRGGLAQVSVIAAAIFSGISGSALADIAGLGAIEVKAMRERGYPAEFAAAVSVASSVMAPIMPPSIAFIVYA
SMANASVARMFMAGIVPATLLAISLMVCNRIIAGRRGYPREEAMPFDLAVRTVIAGLPALGAPAIILIGTMGGYTTVGEA
GILASVYSMLLGFAYRSINLKKVWQAINDTVSVTALIMVIIGFSHFMSWVLAIQQAPQHLAALVLTLTQSPTVLMLLLVA
FLLFIGCFIESAPAKLILVPVLLPVIDQFGIDRVQFGVVMTLALALGIAHPPMGVGLFVVTRVSNVSLERVTMAVLPLLI
PLLVVLIVVALIPSLSTWLPDLVMGAPS
>Mature_427_residues
PAFLFVLFIGLMALGVPVTMAIGASALSVFAMSGFTDALYVLPQQMLEGIDSPSMMSIPFFILAGNLMNAVGVTDRIFSL
ALVLVGRFRGGLAQVSVIAAAIFSGISGSALADIAGLGAIEVKAMRERGYPAEFAAAVSVASSVMAPIMPPSIAFIVYAS
MANASVARMFMAGIVPATLLAISLMVCNRIIAGRRGYPREEAMPFDLAVRTVIAGLPALGAPAIILIGTMGGYTTVGEAG
ILASVYSMLLGFAYRSINLKKVWQAINDTVSVTALIMVIIGFSHFMSWVLAIQQAPQHLAALVLTLTQSPTVLMLLLVAF
LLFIGCFIESAPAKLILVPVLLPVIDQFGIDRVQFGVVMTLALALGIAHPPMGVGLFVVTRVSNVSLERVTMAVLPLLIP
LLVVLIVVALIPSLSTWLPDLVMGAPS

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=410, Percent_Identity=32.6829268292683, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44862; Mature: 44731

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFLFVLFIGLMALGVPVTMAIGASALSVFAMSGFTDALYVLPQQMLEGIDSPSMMSIP
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHH
FFILAGNLMNAVGVTDRIFSLALVLVGRFRGGLAQVSVIAAAIFSGISGSALADIAGLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCH
IEVKAMRERGYPAEFAAAVSVASSVMAPIMPPSIAFIVYASMANASVARMFMAGIVPATL
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAISLMVCNRIIAGRRGYPREEAMPFDLAVRTVIAGLPALGAPAIILIGTMGGYTTVGEA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHCHH
GILASVYSMLLGFAYRSINLKKVWQAINDTVSVTALIMVIIGFSHFMSWVLAIQQAPQHL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALVLTLTQSPTVLMLLLVAFLLFIGCFIESAPAKLILVPVLLPVIDQFGIDRVQFGVVM
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
TLALALGIAHPPMGVGLFVVTRVSNVSLERVTMAVLPLLIPLLVVLIVVALIPSLSTWLP
HHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLVMGAPS
HHHCCCCC
>Mature Secondary Structure 
PAFLFVLFIGLMALGVPVTMAIGASALSVFAMSGFTDALYVLPQQMLEGIDSPSMMSIP
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHH
FFILAGNLMNAVGVTDRIFSLALVLVGRFRGGLAQVSVIAAAIFSGISGSALADIAGLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCH
IEVKAMRERGYPAEFAAAVSVASSVMAPIMPPSIAFIVYASMANASVARMFMAGIVPATL
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAISLMVCNRIIAGRRGYPREEAMPFDLAVRTVIAGLPALGAPAIILIGTMGGYTTVGEA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHCHH
GILASVYSMLLGFAYRSINLKKVWQAINDTVSVTALIMVIIGFSHFMSWVLAIQQAPQHL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALVLTLTQSPTVLMLLLVAFLLFIGCFIESAPAKLILVPVLLPVIDQFGIDRVQFGVVM
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
TLALALGIAHPPMGVGLFVVTRVSNVSLERVTMAVLPLLIPLLVVLIVVALIPSLSTWLP
HHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLVMGAPS
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]