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The map label for this gene is ykgC [H]

Identifier: 91784304

GI number: 91784304

Start: 3263103

End: 3264503

Strand: Reverse

Name: ykgC [H]

Synonym: Bxe_A1496

Alternate gene names: 91784304

Gene position: 3264503-3263103 (Counterclockwise)

Preceding gene: 91784305

Following gene: 91784303

Centisome position: 66.68

GC content: 65.88

Gene sequence:

>1401_bases
ATGCCACAGCACTTCAATGCAGTCGTAATCGGTACAGGACAAGGCGGCTCGCCGCTGGCGGTGCGTCTCGGTCAAAGCGG
CCGTAAAACCGCGGTCATTGAACGCGCGGCCTTCGGCGGCACGTGCGTGAACGTGGGCTGCACGCCCACCAAATCCTATG
TTGCCAGCGCTCGCGCAGCGCATGTCGCGCGCCATTGCGCGGAACTCGGCGTGCAGGTGAGCGGAGCGATCAGCGTCGAT
CTGGCCGCGGTCAAGGCGCGCAAGGACAGGATCATCGGGCAGTCGCGCGACGGCGTCGAGAAATGGCTGCGCGGCGCGCA
GAACGTGAGCGTGTTCAACGGCCACGCGCGCTTCACCGGCGCGCATACGCTCGCCATCAGCGGGCCGGACGGCACGGTGC
TCGAAGAGATCAGCGCCGACGAAATCTTCATCAACACCGGCACGCGCGCCGTCGTGCCGCCGCTCGAAGGCATCGGGCGG
ATTCGCTACTACACCAACTCCAACCTGCTTGAACTGACGGAATTGCCGGATCATCTGGTGATTGTCGGCGGCAGCTATAT
CGCACTCGAATTCGCGCAGATCTTTCGCCGCTTCGGCAGCCGTGTGACCGTGCTGGTGCGCGGCGAACGCGTGCTCACTC
GCGAGGACGCCGATTTTGCCGAATCCGTGCGGAAGGTGCTCGCCCGCGAGGGTGTGGAGTTCCGCTTCGGCGTGCAGCCT
TCGCGGGTCGAGCCGCATCCGCATCATCCGGACGAAGTGTGCATCGGCTTCGAGCAGAACATTCCCGCGCTCGAAGCGTC
GCACCTGCTGTTCGCCACCGGCCGCGAGCCGAATACCGACGACCTCGGCCTCGCGGCCGCCGGCATCACGACGGACCGGC
ACGGCACGATTCCGGTCGACGGCCAGTTGCGTACCAACGTGCCAGGCGTGTGGGCCATCGGCGACGTGAACGGGCGTGGC
GCTTTCACTCACACGTCCTACGACGACTTTCAGATCGTCGCGGCCAACCTGCTCGACGGCGGCGCGCGCAGTGTCGATAC
GCGGATCATGGCGTATGCGGTGTTCGTCGATCCGCCGCTGGCACGCGTGGGGGCTTCGGAGGCCGAGGTGCGCAAAGCGG
GGCGCCCCGCGCTGATCGCCACCATGCCGATGTCGCGGGTGGGCCGCGCCCGCGAACGCGGCGAGACCGACGGCTTCATG
AAGGTGATGGTCGACCGCGAGAGCAGGCAGATTCTCGGCGCGGCCATTCACGGCATCGAAGGCGACGAGGCGATTCATAC
CTTCATCGACATCATGGCGGCGGGCGCGCCGTATCCGACCTTGCAGTACGCCATGCATATTCATCCCACCATCAGTGAAC
TGGTGCCGACCCTGCTCGACGGGCTCAAACCCATGCAGTGA

Upstream 100 bases:

>100_bases
CGCACGGCAACCAACTGAGGCAATCGACAACCCGGCATGGTGATTCGAGGCGTGGAGGGTAAGATGCTACGACCTGCACT
CCAGCCTCGGGAGCGTTGCC

Downstream 100 bases:

>100_bases
GCGGCGCGCACGAGCGGAGCACCTGCGATGAAGCGCGCAATCAGAAGCGGCAATCTGTTCGACCCCGGCGCGCCGGCGGG
CGTGGACGAGCAGATCGACA

Product: mercuric reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MPQHFNAVVIGTGQGGSPLAVRLGQSGRKTAVIERAAFGGTCVNVGCTPTKSYVASARAAHVARHCAELGVQVSGAISVD
LAAVKARKDRIIGQSRDGVEKWLRGAQNVSVFNGHARFTGAHTLAISGPDGTVLEEISADEIFINTGTRAVVPPLEGIGR
IRYYTNSNLLELTELPDHLVIVGGSYIALEFAQIFRRFGSRVTVLVRGERVLTREDADFAESVRKVLAREGVEFRFGVQP
SRVEPHPHHPDEVCIGFEQNIPALEASHLLFATGREPNTDDLGLAAAGITTDRHGTIPVDGQLRTNVPGVWAIGDVNGRG
AFTHTSYDDFQIVAANLLDGGARSVDTRIMAYAVFVDPPLARVGASEAEVRKAGRPALIATMPMSRVGRARERGETDGFM
KVMVDRESRQILGAAIHGIEGDEAIHTFIDIMAAGAPYPTLQYAMHIHPTISELVPTLLDGLKPMQ

Sequences:

>Translated_466_residues
MPQHFNAVVIGTGQGGSPLAVRLGQSGRKTAVIERAAFGGTCVNVGCTPTKSYVASARAAHVARHCAELGVQVSGAISVD
LAAVKARKDRIIGQSRDGVEKWLRGAQNVSVFNGHARFTGAHTLAISGPDGTVLEEISADEIFINTGTRAVVPPLEGIGR
IRYYTNSNLLELTELPDHLVIVGGSYIALEFAQIFRRFGSRVTVLVRGERVLTREDADFAESVRKVLAREGVEFRFGVQP
SRVEPHPHHPDEVCIGFEQNIPALEASHLLFATGREPNTDDLGLAAAGITTDRHGTIPVDGQLRTNVPGVWAIGDVNGRG
AFTHTSYDDFQIVAANLLDGGARSVDTRIMAYAVFVDPPLARVGASEAEVRKAGRPALIATMPMSRVGRARERGETDGFM
KVMVDRESRQILGAAIHGIEGDEAIHTFIDIMAAGAPYPTLQYAMHIHPTISELVPTLLDGLKPMQ
>Mature_465_residues
PQHFNAVVIGTGQGGSPLAVRLGQSGRKTAVIERAAFGGTCVNVGCTPTKSYVASARAAHVARHCAELGVQVSGAISVDL
AAVKARKDRIIGQSRDGVEKWLRGAQNVSVFNGHARFTGAHTLAISGPDGTVLEEISADEIFINTGTRAVVPPLEGIGRI
RYYTNSNLLELTELPDHLVIVGGSYIALEFAQIFRRFGSRVTVLVRGERVLTREDADFAESVRKVLAREGVEFRFGVQPS
RVEPHPHHPDEVCIGFEQNIPALEASHLLFATGREPNTDDLGLAAAGITTDRHGTIPVDGQLRTNVPGVWAIGDVNGRGA
FTHTSYDDFQIVAANLLDGGARSVDTRIMAYAVFVDPPLARVGASEAEVRKAGRPALIATMPMSRVGRARERGETDGFMK
VMVDRESRQILGAAIHGIEGDEAIHTFIDIMAAGAPYPTLQYAMHIHPTISELVPTLLDGLKPMQ

Specific function: Unknown

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=458, Percent_Identity=27.292576419214, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI50301238, Length=472, Percent_Identity=29.6610169491525, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI22035672, Length=457, Percent_Identity=28.8840262582057, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI148277065, Length=460, Percent_Identity=26.0869565217391, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI33519430, Length=460, Percent_Identity=26.0869565217391, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI33519428, Length=460, Percent_Identity=26.0869565217391, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI33519426, Length=460, Percent_Identity=26.0869565217391, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI148277071, Length=460, Percent_Identity=26.0869565217391, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI291045266, Length=437, Percent_Identity=26.3157894736842, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI291045268, Length=431, Percent_Identity=25.2900232018561, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI87081717, Length=463, Percent_Identity=36.9330453563715, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1786307, Length=452, Percent_Identity=30.9734513274336, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI87082354, Length=453, Percent_Identity=28.2560706401766, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789915, Length=472, Percent_Identity=28.8135593220339, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI32565766, Length=462, Percent_Identity=28.7878787878788, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI17557007, Length=474, Percent_Identity=28.6919831223629, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71983429, Length=455, Percent_Identity=26.3736263736264, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71983419, Length=455, Percent_Identity=26.3736263736264, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71982272, Length=443, Percent_Identity=27.0880361173815, Blast_Score=124, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6321091, Length=461, Percent_Identity=28.1995661605206, Blast_Score=180, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6325166, Length=476, Percent_Identity=26.6806722689076, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6325240, Length=437, Percent_Identity=24.9427917620137, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21358499, Length=455, Percent_Identity=29.4505494505495, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24640553, Length=486, Percent_Identity=27.3662551440329, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24640549, Length=486, Percent_Identity=27.3662551440329, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24640551, Length=486, Percent_Identity=27.3662551440329, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17737741, Length=477, Percent_Identity=24.1090146750524, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: NA

Molecular weight: Translated: 49995; Mature: 49863

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQHFNAVVIGTGQGGSPLAVRLGQSGRKTAVIERAAFGGTCVNVGCTPTKSYVASARAA
CCCCCCEEEEECCCCCCCEEEEECCCCCCEEEEEHHCCCCEEEECCCCCCHHHHHHHHHH
HVARHCAELGVQVSGAISVDLAAVKARKDRIIGQSRDGVEKWLRGAQNVSVFNGHARFTG
HHHHHHHHCCCEEECEEEEEHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCEEEEC
AHTLAISGPDGTVLEEISADEIFINTGTRAVVPPLEGIGRIRYYTNSNLLELTELPDHLV
EEEEEEECCCCHHHHHCCCCEEEEECCCEEECCCHHCCCEEEEEECCCEEEEECCCCEEE
IVGGSYIALEFAQIFRRFGSRVTVLVRGERVLTREDADFAESVRKVLAREGVEFRFGVQP
EECCCHHHHHHHHHHHHHCCEEEEEEECCEEEECCCCHHHHHHHHHHHHCCCEEEECCCC
SRVEPHPHHPDEVCIGFEQNIPALEASHLLFATGREPNTDDLGLAAAGITTDRHGTIPVD
CCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCC
GQLRTNVPGVWAIGDVNGRGAFTHTSYDDFQIVAANLLDGGARSVDTRIMAYAVFVDPPL
CEEECCCCCEEEEECCCCCCCEEECCCCCCEEEEEHHHCCCCHHHCCEEEEEEEEECCCH
ARVGASEAEVRKAGRPALIATMPMSRVGRARERGETDGFMKVMVDRESRQILGAAIHGIE
HHHCCCHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCC
GDEAIHTFIDIMAAGAPYPTLQYAMHIHPTISELVPTLLDGLKPMQ
CCHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PQHFNAVVIGTGQGGSPLAVRLGQSGRKTAVIERAAFGGTCVNVGCTPTKSYVASARAA
CCCCCEEEEECCCCCCCEEEEECCCCCCEEEEEHHCCCCEEEECCCCCCHHHHHHHHHH
HVARHCAELGVQVSGAISVDLAAVKARKDRIIGQSRDGVEKWLRGAQNVSVFNGHARFTG
HHHHHHHHCCCEEECEEEEEHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCEEEEC
AHTLAISGPDGTVLEEISADEIFINTGTRAVVPPLEGIGRIRYYTNSNLLELTELPDHLV
EEEEEEECCCCHHHHHCCCCEEEEECCCEEECCCHHCCCEEEEEECCCEEEEECCCCEEE
IVGGSYIALEFAQIFRRFGSRVTVLVRGERVLTREDADFAESVRKVLAREGVEFRFGVQP
EECCCHHHHHHHHHHHHHCCEEEEEEECCEEEECCCCHHHHHHHHHHHHCCCEEEECCCC
SRVEPHPHHPDEVCIGFEQNIPALEASHLLFATGREPNTDDLGLAAAGITTDRHGTIPVD
CCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCC
GQLRTNVPGVWAIGDVNGRGAFTHTSYDDFQIVAANLLDGGARSVDTRIMAYAVFVDPPL
CEEECCCCCEEEEECCCCCCCEEECCCCCCEEEEEHHHCCCCHHHCCEEEEEEEEECCCH
ARVGASEAEVRKAGRPALIATMPMSRVGRARERGETDGFMKVMVDRESRQILGAAIHGIE
HHHCCCHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCC
GDEAIHTFIDIMAAGAPYPTLQYAMHIHPTISELVPTLLDGLKPMQ
CCHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]