Click here to switch to the map view.

The map label for this gene is aceE [H]

Identifier: 91784260

GI number: 91784260

Start: 3208858

End: 3211554

Strand: Reverse

Name: aceE [H]

Synonym: Bxe_A1541

Alternate gene names: 91784260

Gene position: 3211554-3208858 (Counterclockwise)

Preceding gene: 91784266

Following gene: 91784259

Centisome position: 65.6

GC content: 62.18

Gene sequence:

>2697_bases
ATGTCCGCTGTACCCGACGAAGTCATGAAATATGTCGCCGCCGAAAAAGACGACGATCCCCAGGAAACCGGCGAATGGCT
TGAAGCGCTGGATGGCGTGATTTCTGCTGTGGGCCCCGACCGCGCTCACTACCTCATCGAGAAACAGATCGAATTCGCCC
GTGTGCACGGCGAACATCTGCCGTTCTCCGCCAACACGCCGTACATCAATACGATTCCGGTTTCGCGCCAGGCAAAAATC
CCCGGCGACCAGGACCTCGAACACCGTATCCGCTCGTACACCCGCTGGAACGCCATTGCGATGGTGCTGCGCGCCGGCAA
GGAAACCAACGTCGGCGGCCACATTGCGTCGTTCGCTTCGGCTGCCACGCTGTACGACGTCGGCTACAACCACTTCTGGC
ATGCACCGTCGGCTGAACATGGCGGCGATCTCGTGTTCGTGCAGGGGCACTCGTCGCCGGGTGTGTACTCGCGCGCGTTC
CTGCTCGGCCGCCTGACCGAGAACCAGCTCGACAACTTCCGCCAGGAAGTGGGCGGCGAGGGCATCTCGTCGTACCCTCA
CCCGTGGCTGATGCCGGACTTCTGGCAATTCCCGACCGTCTCGATGGGCCTCGGCCCGATCATGGCGATCTATCAGGCGC
GCTTCATGAAGTACCTGCAGGCGCGCGGCATTACGAAAACCGAAGGCCGCAAGGTGTGGGCTTTCCTCGGCGACGGCGAA
ACGGACGAGCCGGAATCGCTCGGCGCGATCGGCATGGCCGGCCGCGAACGCCTCGACAACCTCGTGTTCGTGATCAACTG
CAACCTGCAGCGCCTCGACGGTCCGGTGCGCGGTAACGGCAAGATCATCCAGGAACTGGAAAGCGAATTCCGCGGCGCGG
GCTGGAACGTCATCAAGGTCATCTGGGGCAGCCGCTGGGATGCGCTGTTCCAACGCGACAAATCGGGCGCGTTGATGCGC
CGCATGATGGAAGTGGTCGACGGCGAGTACCAGACGTACAAGTCGGAGTCGGGCGCGTATGTGCGCGAACACTTCTTCAA
CACGCCTGAGCTGAAGGCGTTGGTCGCCGAATGGTCCGACGAGGAAATCTGGAACCTGAACCGCGGCGGCCACGATCCGC
ACAAGATCTATGCGGCGTTCCAGGAAGCGTCGAATTCGCAGGGCCAGCCCACCGTCATCCTCGCGAAGACGATCAAGGGC
TATGGCATGGGCGAAGCCGGCCAGGCCATGAACATCACCCACCAGCAGAAAAAGCTGCACGTGGATCAGCTGAAGAAATT
CCGCGACCAGTTCCGCCTGCCGATCTCCGACGAAGATCTCGTCAACGTGCCGTACCTCAAGTTCGAAGAAGGTTCGAAAG
AACTCGAGTATATGCGCGCCCGCCGGCAGGATCTCGGCGGCTATCTGCCGGCGCGCCGTCAGAAGGCCGAGTCGCTGCCG
GTGCCGGAACTGTCGGTATTCGAGCCGCTGCTCAAGGGCACGGGCGAAGGCCGCGAGATCTCCACCACGATGGCGTTCGT
GCGGATCCTGAACATCCTGCTCAAAGACAAGGCGCTTGGTAAGCGTATCGTGCCGATCGTGCCGGACGAGTCGCGCACCT
TCGGCATGGAAGGCCTGTTCCGCCAGATCGGTATCTGGAATCAGGACGGCCAGAAGTACGTGCCGGAAGATTCCGACCAG
CTCATGTTCTACCGTGAGTCGGAAACCGGGCAGATCCTGCAGGAAGGTATCAACGAAGCCGGCGGCATGTCGGACTGGAT
CGCGGCCGCGACGTCGTACTCGACGCACGGCGAGATCATGATCCCGTTCTACATCTTCTACTCGATGTTCGGCTTCCAGC
GCATCGGCGACCTGGCATGGGCGGCCGGCGACATGCGTTCGCGCGGCTTCCTGCTGGGCGGCACCGCGGGCCGCACCACG
CTGAACGGCGAAGGTCTGCAGCACGAAGACGGCCACTCGCTGCTGTGGGCGGCTTCGGTGCCGAACTGCATCAGCTACGA
CCCGACGTTCGGCTACGAACTCGCGGTCATCATGCAGGACGGTCTGCGCCGCATGGTCGCGGAACAGGAAGACGTGTACT
ACTACGTCACGGTGATGAACGAGAACTACGAGCACCCGGCGATCCCGCAGGGCGACTCGGTGGCCGCGGATATCATCAAA
GGCATGTACGCGTTCCGCAAGGCCGAGGCCGACAGGAAGACGCCGCGCGTGCAGTTGATGGGCGCGGGCACGATCTTCAA
TGAAGTGATCGCCGCCGCCGACCTGCTGAAGAACGACTGGGGCGTTGCCGCCGACCTGTGGAGCGTGCCGAGCTTTACCG
AACTCGCGCGCGAAGGCCACGAAGTGCAGCGTTGGAACCTGCTGCACCCGACCGAAGAAAAGAAGCTCTCGCACGTCGAG
AAGCTGCTGAAAGACGCGCAAGGTCCGGTTATCGCCTCGACCGATTACGTGCGTGCGCTGACCGAGCAGATCCGCGCGTT
CGTGCCGCAGAAGTTCGTGGTGCTGGGCACGGATGGCTACGGCCGTTCGGACACGCGCGAAAAGCTGCGCCACTTTTTCG
AAGTCGACCGCTACTGGGTCACGGTTGCCGCGTTGAATGCACTGGCAGATGAAGGCACGATCGAACGCAAGGTCGTCGCC
GAGGCGCTCAAGAAATATAACCTTGATCCCGCCAAACCCAACCCGATGACCGTCTAA

Upstream 100 bases:

>100_bases
GGACGTCGGGACCCTTATTACAATCGGCCGAAGCTGCCGCGGCCGTGCTTCGTCCGCGTCGTCTGTTCAAAGAGCGTTCC
TCTATACCCAGGAGACGAGC

Downstream 100 bases:

>100_bases
GGCATCCTTCCCCGTGTGCCACGGCGTGCGCGCCCGCCCCTGTTCGACAGGGGCCGGGTGCGTGCGCGGCCCAGGAGACA
CTAACAATGAGTCAAGCGAT

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 898; Mature: 897

Protein sequence:

>898_residues
MSAVPDEVMKYVAAEKDDDPQETGEWLEALDGVISAVGPDRAHYLIEKQIEFARVHGEHLPFSANTPYINTIPVSRQAKI
PGDQDLEHRIRSYTRWNAIAMVLRAGKETNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGVYSRAF
LLGRLTENQLDNFRQEVGGEGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGITKTEGRKVWAFLGDGE
TDEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFQRDKSGALMR
RMMEVVDGEYQTYKSESGAYVREHFFNTPELKALVAEWSDEEIWNLNRGGHDPHKIYAAFQEASNSQGQPTVILAKTIKG
YGMGEAGQAMNITHQQKKLHVDQLKKFRDQFRLPISDEDLVNVPYLKFEEGSKELEYMRARRQDLGGYLPARRQKAESLP
VPELSVFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRIVPIVPDESRTFGMEGLFRQIGIWNQDGQKYVPEDSDQ
LMFYRESETGQILQEGINEAGGMSDWIAAATSYSTHGEIMIPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLLWAASVPNCISYDPTFGYELAVIMQDGLRRMVAEQEDVYYYVTVMNENYEHPAIPQGDSVAADIIK
GMYAFRKAEADRKTPRVQLMGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHEVQRWNLLHPTEEKKLSHVE
KLLKDAQGPVIASTDYVRALTEQIRAFVPQKFVVLGTDGYGRSDTREKLRHFFEVDRYWVTVAALNALADEGTIERKVVA
EALKKYNLDPAKPNPMTV

Sequences:

>Translated_898_residues
MSAVPDEVMKYVAAEKDDDPQETGEWLEALDGVISAVGPDRAHYLIEKQIEFARVHGEHLPFSANTPYINTIPVSRQAKI
PGDQDLEHRIRSYTRWNAIAMVLRAGKETNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGVYSRAF
LLGRLTENQLDNFRQEVGGEGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGITKTEGRKVWAFLGDGE
TDEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFQRDKSGALMR
RMMEVVDGEYQTYKSESGAYVREHFFNTPELKALVAEWSDEEIWNLNRGGHDPHKIYAAFQEASNSQGQPTVILAKTIKG
YGMGEAGQAMNITHQQKKLHVDQLKKFRDQFRLPISDEDLVNVPYLKFEEGSKELEYMRARRQDLGGYLPARRQKAESLP
VPELSVFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRIVPIVPDESRTFGMEGLFRQIGIWNQDGQKYVPEDSDQ
LMFYRESETGQILQEGINEAGGMSDWIAAATSYSTHGEIMIPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLLWAASVPNCISYDPTFGYELAVIMQDGLRRMVAEQEDVYYYVTVMNENYEHPAIPQGDSVAADIIK
GMYAFRKAEADRKTPRVQLMGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHEVQRWNLLHPTEEKKLSHVE
KLLKDAQGPVIASTDYVRALTEQIRAFVPQKFVVLGTDGYGRSDTREKLRHFFEVDRYWVTVAALNALADEGTIERKVVA
EALKKYNLDPAKPNPMTV
>Mature_897_residues
SAVPDEVMKYVAAEKDDDPQETGEWLEALDGVISAVGPDRAHYLIEKQIEFARVHGEHLPFSANTPYINTIPVSRQAKIP
GDQDLEHRIRSYTRWNAIAMVLRAGKETNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGVYSRAFL
LGRLTENQLDNFRQEVGGEGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGITKTEGRKVWAFLGDGET
DEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFQRDKSGALMRR
MMEVVDGEYQTYKSESGAYVREHFFNTPELKALVAEWSDEEIWNLNRGGHDPHKIYAAFQEASNSQGQPTVILAKTIKGY
GMGEAGQAMNITHQQKKLHVDQLKKFRDQFRLPISDEDLVNVPYLKFEEGSKELEYMRARRQDLGGYLPARRQKAESLPV
PELSVFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRIVPIVPDESRTFGMEGLFRQIGIWNQDGQKYVPEDSDQL
MFYRESETGQILQEGINEAGGMSDWIAAATSYSTHGEIMIPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTL
NGEGLQHEDGHSLLWAASVPNCISYDPTFGYELAVIMQDGLRRMVAEQEDVYYYVTVMNENYEHPAIPQGDSVAADIIKG
MYAFRKAEADRKTPRVQLMGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHEVQRWNLLHPTEEKKLSHVEK
LLKDAQGPVIASTDYVRALTEQIRAFVPQKFVVLGTDGYGRSDTREKLRHFFEVDRYWVTVAALNALADEGTIERKVVAE
ALKKYNLDPAKPNPMTV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=885, Percent_Identity=59.5480225988701, Blast_Score=1088, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100936; Mature: 100805

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPDEVMKYVAAEKDDDPQETGEWLEALDGVISAVGPDRAHYLIEKQIEFARVHGEHL
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVSRQAKIPGDQDLEHRIRSYTRWNAIAMVLRAGKETNVGGHIASFAS
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGVYSRAFLLGRLTENQLDNFRQEVGGE
HHHHHHCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGITKTEGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
TDEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDALFQRDKSGALMRRMMEVVDGEYQTYKSESGAYVREHFFNTPELKALVAEWSD
ECCCHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCHHHHHHHHHCCC
EEIWNLNRGGHDPHKIYAAFQEASNSQGQPTVILAKTIKGYGMGEAGQAMNITHQQKKLH
CHHEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHCC
VDQLKKFRDQFRLPISDEDLVNVPYLKFEEGSKELEYMRARRQDLGGYLPARRQKAESLP
HHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCC
VPELSVFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRIVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHH
RQIGIWNQDGQKYVPEDSDQLMFYRESETGQILQEGINEAGGMSDWIAAATSYSTHGEIM
HHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEE
IPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAASV
EHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCEEEECCC
PNCISYDPTFGYELAVIMQDGLRRMVAEQEDVYYYVTVMNENYEHPAIPQGDSVAADIIK
CCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYAFRKAEADRKTPRVQLMGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGH
HHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHCCC
EVQRWNLLHPTEEKKLSHVEKLLKDAQGPVIASTDYVRALTEQIRAFVPQKFVVLGTDGY
CEEECCCCCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCEEEEEECCCC
GRSDTREKLRHFFEVDRYWVTVAALNALADEGTIERKVVAEALKKYNLDPAKPNPMTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVPDEVMKYVAAEKDDDPQETGEWLEALDGVISAVGPDRAHYLIEKQIEFARVHGEHL
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVSRQAKIPGDQDLEHRIRSYTRWNAIAMVLRAGKETNVGGHIASFAS
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGVYSRAFLLGRLTENQLDNFRQEVGGE
HHHHHHCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGITKTEGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
TDEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDALFQRDKSGALMRRMMEVVDGEYQTYKSESGAYVREHFFNTPELKALVAEWSD
ECCCHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCHHHHHHHHHCCC
EEIWNLNRGGHDPHKIYAAFQEASNSQGQPTVILAKTIKGYGMGEAGQAMNITHQQKKLH
CHHEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHCC
VDQLKKFRDQFRLPISDEDLVNVPYLKFEEGSKELEYMRARRQDLGGYLPARRQKAESLP
HHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCC
VPELSVFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRIVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHH
RQIGIWNQDGQKYVPEDSDQLMFYRESETGQILQEGINEAGGMSDWIAAATSYSTHGEIM
HHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEE
IPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAASV
EHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCEEEECCC
PNCISYDPTFGYELAVIMQDGLRRMVAEQEDVYYYVTVMNENYEHPAIPQGDSVAADIIK
CCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYAFRKAEADRKTPRVQLMGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGH
HHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHCCC
EVQRWNLLHPTEEKKLSHVEKLLKDAQGPVIASTDYVRALTEQIRAFVPQKFVVLGTDGY
CEEECCCCCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCEEEEEECCCC
GRSDTREKLRHFFEVDRYWVTVAALNALADEGTIERKVVAEALKKYNLDPAKPNPMTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]