Click here to switch to the map view.

The map label for this gene is dapA [H]

Identifier: 91784216

GI number: 91784216

Start: 3161307

End: 3162269

Strand: Reverse

Name: dapA [H]

Synonym: Bxe_A1585

Alternate gene names: 91784216

Gene position: 3162269-3161307 (Counterclockwise)

Preceding gene: 91784217

Following gene: 91784215

Centisome position: 64.59

GC content: 63.55

Gene sequence:

>963_bases
ATGACTAACGGCAACCAAAGCGGCAACCAAAGCGGCAACCAAAGCGGCAACCACAGCGGCAACCAGGGCAGCAACGACGG
CGTTCAGATTCGCGGCAGCATTCCTGCCATCATCACCCCGATGCTCGAAGACGGCAGTCTGGATCTGCCGGCGTTTCGCA
AACTGATCGACTGGCACGTCGCAGAGGGCACGAACGCTCTCGTGGTGGTCGGTACGAGCGGCGAGTCGGCCACGCTGTCG
GTCGAAGAACACGTGCTAATGGTCAAGACCGCGGTCGAGCACACGGCGGGCCGGATTCCGGTGATCGCGGGCTCGGGCGG
CAACTCCACGACCGAGGCGATCGAACTTACCCAGCGCGCCAAAGAGGTCGGCGCCGACGCCACGCTCCAGGTCGTGCCGT
ACTACAACAAGCCGACGCAGGAGGGCATCTACCGCCACTTCGCGAAGATCGCGGAAACCGTCGATCTGCCGGTGATTCTG
TACAACGTGCCGGGCCGCACCGTTGCCGACATGAGCAACGAAACCATCCTGCGCCTCGCGCAGGTGCCAGGTATCATCGG
TGTGAAGGAAGCGACCGGCAATATCGATCGCGCCGCGCATCTCATCAAGTTTGCGCCGTCGCACTTCGGCATCTACAGCG
GCGACGATCCCACCGCCATCGCGCTGATGCTGCTCGGCGGCCACGGCAATATTTCGGTCACCGCCAACGTCGTGCCGCGC
GCCATGAGCGAGCTCTGCAAGGCCGCTCTCGCCGCGGACGTTAAGACCGCCCGTGAGATTCATCTGAAACTCCTGTCGCT
GCATAAGAACCTGTTCGTCGAATCGAATCCGATTCCGGCCAAATGGGCGCTGCAGCAACTGGGTCGTGTGCAGGGCGGAA
TCCGCCTGCCGCTTACGCCGCTCGACCCGCAGTACCACGAAGTGGTACGCGGCGCGCTGCGCGAAGCGGGCCTGCTGGGC
TAG

Upstream 100 bases:

>100_bases
CGCTCAGACGACCCCGCGCAGGCGGCAGCCCCGCCTTGTTACGAGTTGGCTGGCTAATCCGCTACAATCGCGGTTTACCT
GATCAAATTCATGGCGTTTC

Downstream 100 bases:

>100_bases
GCGGATAGCGTCCGCGGCAACCCGTAGCGCTAACGAAAGCCTGCCACCGGCACTCCCTTAACCGACGTCGATCCAGCCCG
CGTTCCCGGCACACAGAACC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTNGNQSGNQSGNQSGNHSGNQGSNDGVQIRGSIPAIITPMLEDGSLDLPAFRKLIDWHVAEGTNALVVVGTSGESATLS
VEEHVLMVKTAVEHTAGRIPVIAGSGGNSTTEAIELTQRAKEVGADATLQVVPYYNKPTQEGIYRHFAKIAETVDLPVIL
YNVPGRTVADMSNETILRLAQVPGIIGVKEATGNIDRAAHLIKFAPSHFGIYSGDDPTAIALMLLGGHGNISVTANVVPR
AMSELCKAALAADVKTAREIHLKLLSLHKNLFVESNPIPAKWALQQLGRVQGGIRLPLTPLDPQYHEVVRGALREAGLLG

Sequences:

>Translated_320_residues
MTNGNQSGNQSGNQSGNHSGNQGSNDGVQIRGSIPAIITPMLEDGSLDLPAFRKLIDWHVAEGTNALVVVGTSGESATLS
VEEHVLMVKTAVEHTAGRIPVIAGSGGNSTTEAIELTQRAKEVGADATLQVVPYYNKPTQEGIYRHFAKIAETVDLPVIL
YNVPGRTVADMSNETILRLAQVPGIIGVKEATGNIDRAAHLIKFAPSHFGIYSGDDPTAIALMLLGGHGNISVTANVVPR
AMSELCKAALAADVKTAREIHLKLLSLHKNLFVESNPIPAKWALQQLGRVQGGIRLPLTPLDPQYHEVVRGALREAGLLG
>Mature_319_residues
TNGNQSGNQSGNQSGNHSGNQGSNDGVQIRGSIPAIITPMLEDGSLDLPAFRKLIDWHVAEGTNALVVVGTSGESATLSV
EEHVLMVKTAVEHTAGRIPVIAGSGGNSTTEAIELTQRAKEVGADATLQVVPYYNKPTQEGIYRHFAKIAETVDLPVILY
NVPGRTVADMSNETILRLAQVPGIIGVKEATGNIDRAAHLIKFAPSHFGIYSGDDPTAIALMLLGGHGNISVTANVVPRA
MSELCKAALAADVKTAREIHLKLLSLHKNLFVESNPIPAKWALQQLGRVQGGIRLPLTPLDPQYHEVVRGALREAGLLG

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=300, Percent_Identity=25.3333333333333, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI13540533, Length=236, Percent_Identity=27.5423728813559, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1788823, Length=289, Percent_Identity=53.2871972318339, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1786463, Length=280, Percent_Identity=35, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI87082415, Length=268, Percent_Identity=33.5820895522388, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1789620, Length=233, Percent_Identity=27.8969957081545, Blast_Score=111, Evalue=5e-26,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33883; Mature: 33752

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNGNQSGNQSGNQSGNHSGNQGSNDGVQIRGSIPAIITPMLEDGSLDLPAFRKLIDWHV
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHH
AEGTNALVVVGTSGESATLSVEEHVLMVKTAVEHTAGRIPVIAGSGGNSTTEAIELTQRA
CCCCCEEEEEECCCCCEEEEHHHHEEHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHH
KEVGADATLQVVPYYNKPTQEGIYRHFAKIAETVDLPVILYNVPGRTVADMSNETILRLA
HHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEHHCCCHHHHHHH
QVPGIIGVKEATGNIDRAAHLIKFAPSHFGIYSGDDPTAIALMLLGGHGNISVTANVVPR
HCCCCEEEHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEHHHHHH
AMSELCKAALAADVKTAREIHLKLLSLHKNLFVESNPIPAKWALQQLGRVQGGIRLPLTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCEECCCC
LDPQYHEVVRGALREAGLLG
CCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TNGNQSGNQSGNQSGNHSGNQGSNDGVQIRGSIPAIITPMLEDGSLDLPAFRKLIDWHV
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHH
AEGTNALVVVGTSGESATLSVEEHVLMVKTAVEHTAGRIPVIAGSGGNSTTEAIELTQRA
CCCCCEEEEEECCCCCEEEEHHHHEEHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHH
KEVGADATLQVVPYYNKPTQEGIYRHFAKIAETVDLPVILYNVPGRTVADMSNETILRLA
HHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEHHCCCHHHHHHH
QVPGIIGVKEATGNIDRAAHLIKFAPSHFGIYSGDDPTAIALMLLGGHGNISVTANVVPR
HCCCCEEEHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEHHHHHH
AMSELCKAALAADVKTAREIHLKLLSLHKNLFVESNPIPAKWALQQLGRVQGGIRLPLTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCEECCCC
LDPQYHEVVRGALREAGLLG
CCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]