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The map label for this gene is hflK [H]

Identifier: 91784200

GI number: 91784200

Start: 3143658

End: 3145040

Strand: Reverse

Name: hflK [H]

Synonym: Bxe_A1601

Alternate gene names: 91784200

Gene position: 3145040-3143658 (Counterclockwise)

Preceding gene: 91784201

Following gene: 91784199

Centisome position: 64.24

GC content: 65.65

Gene sequence:

>1383_bases
GTGAACGATTACAACGAGCGGAGTATCTGGCTGCGCATGCGCGCCATGCTTTCATTGAACGATCCGCGCTGGGGCCGGGG
GGACGGCAATGGCGACCGGCAACGTCCAAACGAGCCCAAACGTCCGCCGACCAAGGACGGTGAAGGGCCGCCCGATCTCG
ACGAGATGTGGCGCGATTTCAACCGCCGTTTGAGCCGCGTGTTTGGCCGCAAGGGCGGCGGCGCGGGTGGCGGCCGGCCG
GACAACGGTCGTGGCGCGCGCATTGGCTTGGGCATCGTGATCGGCGTGCTGCTGGCCATTTATCTCGGCAGCGGGGTGTT
CGTCGTGCAGGACGGCCAGGCCGGCGTCGTGATGCAGTTCGGCAAGTATCGCTACACGGCGGGTCAGGGCGTGCACTGGC
GTCTGCCGTATCCGTTCGAAGCGCATGAGCTCGTCAATATCGGCCAGGTCCGCCAGGTGGAGATCGGCCGCAATAACGTG
GTGCGTCTCGCGAACGTGAAAGACGCGTCGATGCTCACGCACGACGCGGATATCGTCGACGTGCGCTTCGCCGTGCAATA
CCAGGTGAAGAAGCCGACCGACTACCTGTTCCGCAGCGTCGATCCCGATCAGGGTGTGATGCAGGCTGCTCAGGCGGCGG
TGCGCAGCATCGTCGGCGCGCGCAGCACCAATGACATCCTCTATCAGGATCGCGAAACAATTCGCCAGCAGCTGATGGCG
GCGATCCAGCAATCCCTGGATGAATACCAGTCCGGACTTGCCGTGACCGGTGTGACCATCCAGGGCGTGCAGGCGCCCGA
CCAGGTGCAGGCCGCGTTTGACGACGCCGCCAAAGTCCGTCAGGAAAACGAGCGCGCGAAACGCGACGCCGAGGCCTACG
CCGCGGATCTGTTGCCGCGCGCGCAAGCCGACGTGGCTCGCCAGATCGACGAAGCCAAAACGTACAGCGACAAGACGGTG
GCCCAGGCGCAAGGCGACGCCGAGCGCTTCAAGCAGGTCTACGCGCAGTACTCGAAAGCGCCCGCTGTGATTCGCGAGCG
CATGTATCTGGAAACCATGCAGCAGATCTATTCGAATACGACCAAGGTGTTTGTGGACAGCAAGAGCGGCAACAATGTGC
TGTATCTGCCGCTCGACAAGCTGGTCGAGCAGACCCGTCAGCGGGCGGCCGACGCCGCTTCGGGTGCCGTGGCCGCCGCC
GCGCCGCAGGCAGCGAGCGGTGCCGCGCTGCCGTCGGCCGTGCCGTCTGCCTCTGCAACCGGCGCCGCAGCTTCCGCGCC
GGCCGCGGTTGCCACGCCCGCCAGCCAGGCCGCAGCCAGCAGCGACGCGCTGCGCTCACGCGACTCCTTCCGCAGCCGTA
TGCGCGAAGACGACGTTCAATAA

Upstream 100 bases:

>100_bases
CGGTCGGCGGCACCACGCGACGACCGCAAGGTCCCAGAACTCGGGCATTGACCCGTTCCAATTGCACTGACCCGCTGTCT
ACTCTGGTGAACGAACACAG

Downstream 100 bases:

>100_bases
GGAGCGCATAACATGAACAGGATCATTGCGCTCGTCGTGGCTGTCGTCATCGTGCTGTTTGCCGCTTCGTCTATGGTGTT
TGTCGTCGATCAGCGGCATC

Product: FtsH protease activity modulator HflK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MNDYNERSIWLRMRAMLSLNDPRWGRGDGNGDRQRPNEPKRPPTKDGEGPPDLDEMWRDFNRRLSRVFGRKGGGAGGGRP
DNGRGARIGLGIVIGVLLAIYLGSGVFVVQDGQAGVVMQFGKYRYTAGQGVHWRLPYPFEAHELVNIGQVRQVEIGRNNV
VRLANVKDASMLTHDADIVDVRFAVQYQVKKPTDYLFRSVDPDQGVMQAAQAAVRSIVGARSTNDILYQDRETIRQQLMA
AIQQSLDEYQSGLAVTGVTIQGVQAPDQVQAAFDDAAKVRQENERAKRDAEAYAADLLPRAQADVARQIDEAKTYSDKTV
AQAQGDAERFKQVYAQYSKAPAVIRERMYLETMQQIYSNTTKVFVDSKSGNNVLYLPLDKLVEQTRQRAADAASGAVAAA
APQAASGAALPSAVPSASATGAAASAPAAVATPASQAAASSDALRSRDSFRSRMREDDVQ

Sequences:

>Translated_460_residues
MNDYNERSIWLRMRAMLSLNDPRWGRGDGNGDRQRPNEPKRPPTKDGEGPPDLDEMWRDFNRRLSRVFGRKGGGAGGGRP
DNGRGARIGLGIVIGVLLAIYLGSGVFVVQDGQAGVVMQFGKYRYTAGQGVHWRLPYPFEAHELVNIGQVRQVEIGRNNV
VRLANVKDASMLTHDADIVDVRFAVQYQVKKPTDYLFRSVDPDQGVMQAAQAAVRSIVGARSTNDILYQDRETIRQQLMA
AIQQSLDEYQSGLAVTGVTIQGVQAPDQVQAAFDDAAKVRQENERAKRDAEAYAADLLPRAQADVARQIDEAKTYSDKTV
AQAQGDAERFKQVYAQYSKAPAVIRERMYLETMQQIYSNTTKVFVDSKSGNNVLYLPLDKLVEQTRQRAADAASGAVAAA
APQAASGAALPSAVPSASATGAAASAPAAVATPASQAAASSDALRSRDSFRSRMREDDVQ
>Mature_460_residues
MNDYNERSIWLRMRAMLSLNDPRWGRGDGNGDRQRPNEPKRPPTKDGEGPPDLDEMWRDFNRRLSRVFGRKGGGAGGGRP
DNGRGARIGLGIVIGVLLAIYLGSGVFVVQDGQAGVVMQFGKYRYTAGQGVHWRLPYPFEAHELVNIGQVRQVEIGRNNV
VRLANVKDASMLTHDADIVDVRFAVQYQVKKPTDYLFRSVDPDQGVMQAAQAAVRSIVGARSTNDILYQDRETIRQQLMA
AIQQSLDEYQSGLAVTGVTIQGVQAPDQVQAAFDDAAKVRQENERAKRDAEAYAADLLPRAQADVARQIDEAKTYSDKTV
AQAQGDAERFKQVYAQYSKAPAVIRERMYLETMQQIYSNTTKVFVDSKSGNNVLYLPLDKLVEQTRQRAADAASGAVAAA
APQAASGAALPSAVPSASATGAAASAPAAVATPASQAAASSDALRSRDSFRSRMREDDVQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=293, Percent_Identity=33.1058020477816, Blast_Score=191, Evalue=9e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 50077; Mature: 50077

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDYNERSIWLRMRAMLSLNDPRWGRGDGNGDRQRPNEPKRPPTKDGEGPPDLDEMWRDF
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NRRLSRVFGRKGGGAGGGRPDNGRGARIGLGIVIGVLLAIYLGSGVFVVQDGQAGVVMQF
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEC
GKYRYTAGQGVHWRLPYPFEAHELVNIGQVRQVEIGRNNVVRLANVKDASMLTHDADIVD
CCEEEECCCCEEEECCCCCCHHHHHCCCCEEEEEECCCCEEEEECCCHHHHHHCCCCEEE
VRFAVQYQVKKPTDYLFRSVDPDQGVMQAAQAAVRSIVGARSTNDILYQDRETIRQQLMA
EEEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AIQQSLDEYQSGLAVTGVTIQGVQAPDQVQAAFDDAAKVRQENERAKRDAEAYAADLLPR
HHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AQADVARQIDEAKTYSDKTVAQAQGDAERFKQVYAQYSKAPAVIRERMYLETMQQIYSNT
HHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
TKVFVDSKSGNNVLYLPLDKLVEQTRQRAADAASGAVAAAAPQAASGAALPSAVPSASAT
EEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCC
GAAASAPAAVATPASQAAASSDALRSRDSFRSRMREDDVQ
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDYNERSIWLRMRAMLSLNDPRWGRGDGNGDRQRPNEPKRPPTKDGEGPPDLDEMWRDF
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NRRLSRVFGRKGGGAGGGRPDNGRGARIGLGIVIGVLLAIYLGSGVFVVQDGQAGVVMQF
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEC
GKYRYTAGQGVHWRLPYPFEAHELVNIGQVRQVEIGRNNVVRLANVKDASMLTHDADIVD
CCEEEECCCCEEEECCCCCCHHHHHCCCCEEEEEECCCCEEEEECCCHHHHHHCCCCEEE
VRFAVQYQVKKPTDYLFRSVDPDQGVMQAAQAAVRSIVGARSTNDILYQDRETIRQQLMA
EEEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AIQQSLDEYQSGLAVTGVTIQGVQAPDQVQAAFDDAAKVRQENERAKRDAEAYAADLLPR
HHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AQADVARQIDEAKTYSDKTVAQAQGDAERFKQVYAQYSKAPAVIRERMYLETMQQIYSNT
HHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
TKVFVDSKSGNNVLYLPLDKLVEQTRQRAADAASGAVAAAAPQAASGAALPSAVPSASAT
EEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCC
GAAASAPAAVATPASQAAASSDALRSRDSFRSRMREDDVQ
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]