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The map label for this gene is kup

Identifier: 91784193

GI number: 91784193

Start: 3136738

End: 3138624

Strand: Reverse

Name: kup

Synonym: Bxe_A1608

Alternate gene names: 91784193

Gene position: 3138624-3136738 (Counterclockwise)

Preceding gene: 91784194

Following gene: 91784191

Centisome position: 64.11

GC content: 60.84

Gene sequence:

>1887_bases
ATGACAGATAACAATCACGAGCACAAACAGCCTCTGCCTTCCCTCGCCATTGCCGCGATCGGAGTGGTATTCGGCGATAT
CGGCACGAGTCCGTTGTACTCGTTGAAAGAAGCCTTCAGCCCATCGCACGGCATTCCGCTGACCGATCAATCCATTCTGG
GTGTGATCTCGCTGCTGTTCTGGGCGATCGTGATCGTGGTCGGCGTGAAATATGTGTTGTTCGTGATGCGTGCGGACAAT
AACGGCGAGGGTGGCGTTCTCGCGCTGATGGCGCTGGCGCTGCGCTCGCTCGACGAGAAGTCGAAGATGGCCGGCTTGCT
GATGATGCTCGGCATTTTCGGTGCCTGCATGTTCTATGGTGACGCCGTGATTACACCGGCCATTTCGGTGATCTCGGCGG
TCGAAGGTCTGGAGATTGCCGCGCCGCATCTGTCGCATCTGGTGCTGCCGCTCACGATCGTGATCCTCATCCTGCTGTTC
TGGATTCAACGGCACGGCACGGCCATGGTCGGCCGCCTGTTCGGTCCGATCATGGTGCTATGGTTCGTGGTGCTCGCAGC
GCTCGGCCTGTGGCACATCCTGCAGTCGCCGAGCGTGATCCGCGCGCTCAACCCCTGCTACGCCTACACCTTCATGGCCG
CGCACGTGCTGCAGGCTTACGTGGTGCTCGGCTCGGTCGTGCTGGTGCTGACCGGCGCCGAAGCGCTGTACGCCGACATG
GGCCACTTCGGCGCGAAGCCGATCCGCATGGCGTGGTACGTGCTGGTCATGCCGTCACTGGTGCTGAATTACTTCGGCCA
GGGCGCGCTGCTGATGCACGATCCGAAGGCCATCGAAAATCCGTTCTTCCTGCTCGCGCCGGACTGGGCCTTGCTGCCGC
TCGTCGTGCTGTCCACCATCGCGACGGTGATCGCCTCGCAGGCGGTGATTTCCGGCGCCTATTCGCTGACGAGCCAGGCA
ATCCAGCTCGGCTACGTGCCGCGCATGAAGATTCTGCACACATCGGAGCTGGCGATCGGCCAGATCTATGTACCGGTGGT
GAACTGGATGCTGCTGTTCATCATTCTGTGCATCGTGATTGCTTTCAAGAGTTCGGACAATCTCGCGGCCGCATACGGTA
TTGCGGTGACGGCCACGATGGTGATCACCACGATTCTCGCCTGCGTGGTGATGGTGAAGGTGTGGAACTGGAACAAGCTG
CTGGTGGCGCTGATCATCGGCGTATTCATGACGGTGGATCTCGGCTTTTTCGGCGCTAATCTGCTGAAGGTCGAAGAGGG
CGGCTGGCTGCCGCTCGGCATCGGCGCGTTGCTGTTCTTCCTGCTGATGACCTGGTACAAGGGGCGCATGATCGTCAAGG
AGCGCACGGCGGCCGACGGTATTCCGCTCATGCCGTTCCTGCAAGGGCTGCTCGCGCATCCGCCGCACCGCGTGTCGGGC
ACGGCGATCTATCTGACCGGCAGCGATTCGCTCGTGCCGGTGAGCCTGCTGCACAACCTGAAGCACAACAAGGTGCTGCA
TGAGCGCACCATCTTCCTGACCTTCGTGACGCGCGATATTCCGTACGTGAACGATGCGGACCGTGTGACGGTGAAGGATA
TCGACGGTGGGCTGTATCTCGTCAAGGCGGCCTACGGGTTCAACGAAACGCCTGACGTGAAGGCGGTCCTGCTGGAAGTC
GGCCGCACGCATGACATGACCTTCGAGCTGATGGACACGTCGTTCTTCCTCGCGCGCGAAACGGTGGTGCCGACGCAATT
GCCGGGCATGTCCGTGTGGCGCGAACGTGTGTTCGCGTGGATGCACCAGAACGCCGCCAAGCCGACGGACTTCTTCAGTA
TTCCGGCCAACCGGGTGGTGGAGTTGGGGACGAAGATCGAGATTTGA

Upstream 100 bases:

>100_bases
ACCATCACGTGGTGTATCCACAACAAGCCGGGCGGCGCCAGATGGGCAGTTTAGAATAGCGGTCGTTTTTCCCGCCCAGG
GAACGGATTTCCTCGCGTTT

Downstream 100 bases:

>100_bases
CCGTCGCCGAGGATTCGCGGATGTGCCTGGAAATAGGGGCGAAAAAAAACCCACGTGAATGCGTGGGTTTTTTATTTGCC
GCGTGTTCGGCAGAGCAATG

Product: KUP family K(+) transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MTDNNHEHKQPLPSLAIAAIGVVFGDIGTSPLYSLKEAFSPSHGIPLTDQSILGVISLLFWAIVIVVGVKYVLFVMRADN
NGEGGVLALMALALRSLDEKSKMAGLLMMLGIFGACMFYGDAVITPAISVISAVEGLEIAAPHLSHLVLPLTIVILILLF
WIQRHGTAMVGRLFGPIMVLWFVVLAALGLWHILQSPSVIRALNPCYAYTFMAAHVLQAYVVLGSVVLVLTGAEALYADM
GHFGAKPIRMAWYVLVMPSLVLNYFGQGALLMHDPKAIENPFFLLAPDWALLPLVVLSTIATVIASQAVISGAYSLTSQA
IQLGYVPRMKILHTSELAIGQIYVPVVNWMLLFIILCIVIAFKSSDNLAAAYGIAVTATMVITTILACVVMVKVWNWNKL
LVALIIGVFMTVDLGFFGANLLKVEEGGWLPLGIGALLFFLLMTWYKGRMIVKERTAADGIPLMPFLQGLLAHPPHRVSG
TAIYLTGSDSLVPVSLLHNLKHNKVLHERTIFLTFVTRDIPYVNDADRVTVKDIDGGLYLVKAAYGFNETPDVKAVLLEV
GRTHDMTFELMDTSFFLARETVVPTQLPGMSVWRERVFAWMHQNAAKPTDFFSIPANRVVELGTKIEI

Sequences:

>Translated_628_residues
MTDNNHEHKQPLPSLAIAAIGVVFGDIGTSPLYSLKEAFSPSHGIPLTDQSILGVISLLFWAIVIVVGVKYVLFVMRADN
NGEGGVLALMALALRSLDEKSKMAGLLMMLGIFGACMFYGDAVITPAISVISAVEGLEIAAPHLSHLVLPLTIVILILLF
WIQRHGTAMVGRLFGPIMVLWFVVLAALGLWHILQSPSVIRALNPCYAYTFMAAHVLQAYVVLGSVVLVLTGAEALYADM
GHFGAKPIRMAWYVLVMPSLVLNYFGQGALLMHDPKAIENPFFLLAPDWALLPLVVLSTIATVIASQAVISGAYSLTSQA
IQLGYVPRMKILHTSELAIGQIYVPVVNWMLLFIILCIVIAFKSSDNLAAAYGIAVTATMVITTILACVVMVKVWNWNKL
LVALIIGVFMTVDLGFFGANLLKVEEGGWLPLGIGALLFFLLMTWYKGRMIVKERTAADGIPLMPFLQGLLAHPPHRVSG
TAIYLTGSDSLVPVSLLHNLKHNKVLHERTIFLTFVTRDIPYVNDADRVTVKDIDGGLYLVKAAYGFNETPDVKAVLLEV
GRTHDMTFELMDTSFFLARETVVPTQLPGMSVWRERVFAWMHQNAAKPTDFFSIPANRVVELGTKIEI
>Mature_627_residues
TDNNHEHKQPLPSLAIAAIGVVFGDIGTSPLYSLKEAFSPSHGIPLTDQSILGVISLLFWAIVIVVGVKYVLFVMRADNN
GEGGVLALMALALRSLDEKSKMAGLLMMLGIFGACMFYGDAVITPAISVISAVEGLEIAAPHLSHLVLPLTIVILILLFW
IQRHGTAMVGRLFGPIMVLWFVVLAALGLWHILQSPSVIRALNPCYAYTFMAAHVLQAYVVLGSVVLVLTGAEALYADMG
HFGAKPIRMAWYVLVMPSLVLNYFGQGALLMHDPKAIENPFFLLAPDWALLPLVVLSTIATVIASQAVISGAYSLTSQAI
QLGYVPRMKILHTSELAIGQIYVPVVNWMLLFIILCIVIAFKSSDNLAAAYGIAVTATMVITTILACVVMVKVWNWNKLL
VALIIGVFMTVDLGFFGANLLKVEEGGWLPLGIGALLFFLLMTWYKGRMIVKERTAADGIPLMPFLQGLLAHPPHRVSGT
AIYLTGSDSLVPVSLLHNLKHNKVLHERTIFLTFVTRDIPYVNDADRVTVKDIDGGLYLVKAAYGFNETPDVKAVLLEVG
RTHDMTFELMDTSFFLARETVVPTQLPGMSVWRERVFAWMHQNAAKPTDFFSIPANRVVELGTKIEI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=627, Percent_Identity=50.8771929824561, Blast_Score=657, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_BURXL (Q13X42)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_559399.1
- GeneID:   4005566
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A1608
- HOGENOM:   HBG351154
- OMA:   FILMTTW
- ProtClustDB:   CLSK897039
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 68678; Mature: 68547

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17270818)-; HASH(0x40799744)-; HASH(0x19d61cb8)-; HASH(0x19d9b3a0)-; HASH(0x19d7248c)-; HASH(0x1912bb08)-; HASH(0x19d52c3c)-; HASH(0x19d72558)-; HASH(0x1846d2ac)-; HASH(0x16715ed4)-; HASH(0x178cbd10)-; HASH(0x19d61dc0)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNNHEHKQPLPSLAIAAIGVVFGDIGTSPLYSLKEAFSPSHGIPLTDQSILGVISLLF
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
WAIVIVVGVKYVLFVMRADNNGEGGVLALMALALRSLDEKSKMAGLLMMLGIFGACMFYG
HHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
DAVITPAISVISAVEGLEIAAPHLSHLVLPLTIVILILLFWIQRHGTAMVGRLFGPIMVL
CHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
WFVVLAALGLWHILQSPSVIRALNPCYAYTFMAAHVLQAYVVLGSVVLVLTGAEALYADM
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GHFGAKPIRMAWYVLVMPSLVLNYFGQGALLMHDPKAIENPFFLLAPDWALLPLVVLSTI
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHCCCEEEECCCHHHHHHHHHHHH
ATVIASQAVISGAYSLTSQAIQLGYVPRMKILHTSELAIGQIYVPVVNWMLLFIILCIVI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AFKSSDNLAAAYGIAVTATMVITTILACVVMVKVWNWNKLLVALIIGVFMTVDLGFFGAN
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
LLKVEEGGWLPLGIGALLFFLLMTWYKGRMIVKERTAADGIPLMPFLQGLLAHPPHRVSG
EEEECCCCCEEHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCC
TAIYLTGSDSLVPVSLLHNLKHNKVLHERTIFLTFVTRDIPYVNDADRVTVKDIDGGLYL
EEEEEECCCCCCHHHHHHCCHHHHHHHHHEEEEEEEECCCCCCCCCCEEEEEECCCCEEE
VKAAYGFNETPDVKAVLLEVGRTHDMTFELMDTSFFLARETVVPTQLPGMSVWRERVFAW
EEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCCCCCCHHHHHHHHHHH
MHQNAAKPTDFFSIPANRVVELGTKIEI
HHHCCCCCCCEEECCHHHHHHCCCCCCH
>Mature Secondary Structure 
TDNNHEHKQPLPSLAIAAIGVVFGDIGTSPLYSLKEAFSPSHGIPLTDQSILGVISLLF
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
WAIVIVVGVKYVLFVMRADNNGEGGVLALMALALRSLDEKSKMAGLLMMLGIFGACMFYG
HHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
DAVITPAISVISAVEGLEIAAPHLSHLVLPLTIVILILLFWIQRHGTAMVGRLFGPIMVL
CHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
WFVVLAALGLWHILQSPSVIRALNPCYAYTFMAAHVLQAYVVLGSVVLVLTGAEALYADM
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GHFGAKPIRMAWYVLVMPSLVLNYFGQGALLMHDPKAIENPFFLLAPDWALLPLVVLSTI
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHCCCEEEECCCHHHHHHHHHHHH
ATVIASQAVISGAYSLTSQAIQLGYVPRMKILHTSELAIGQIYVPVVNWMLLFIILCIVI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AFKSSDNLAAAYGIAVTATMVITTILACVVMVKVWNWNKLLVALIIGVFMTVDLGFFGAN
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
LLKVEEGGWLPLGIGALLFFLLMTWYKGRMIVKERTAADGIPLMPFLQGLLAHPPHRVSG
EEEECCCCCEEHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCC
TAIYLTGSDSLVPVSLLHNLKHNKVLHERTIFLTFVTRDIPYVNDADRVTVKDIDGGLYL
EEEEEECCCCCCHHHHHHCCHHHHHHHHHEEEEEEEECCCCCCCCCCEEEEEECCCCEEE
VKAAYGFNETPDVKAVLLEVGRTHDMTFELMDTSFFLARETVVPTQLPGMSVWRERVFAW
EEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCCCCCCHHHHHHHHHHH
MHQNAAKPTDFFSIPANRVVELGTKIEI
HHHCCCCCCCEEECCHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA