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The map label for this gene is btuE [C]

Identifier: 91784136

GI number: 91784136

Start: 3069518

End: 3069997

Strand: Reverse

Name: btuE [C]

Synonym: Bxe_A1665

Alternate gene names: 91784136

Gene position: 3069997-3069518 (Counterclockwise)

Preceding gene: 91784139

Following gene: 91784128

Centisome position: 62.71

GC content: 59.79

Gene sequence:

>480_bases
ATGACATCGATCTATTCGTTTTCGGCACGCACGCTCGGCGGCGAGGAAGTGAGCCTCGAGCAATATAGCGGCAAGGTTTT
GCTGATCGTCAACACGGCGAGCGAATGCGGGTTCACGCCGCAATACGCCGGCTTGCAGAAGCTGTACGAGACCTACGCGG
CGCGCGGGCTCGCGGTACTCGGTTTTCCGTGCAACCAGTTCGGCAAGCAGGAGCCGGGCGACGCAGCGCAGATCGGCAGC
TTCTGCGAAAAGAATTACGGCGTGACGTTCCCGATGTTCGACAAGGTGGACGTGAACGGTGCGAACGCGCATCCGCTATT
CCGTTATCTGACGGGCGAGGCGCCGGGCGTGCTGGGTCTCGAGGCGATCAAGTGGAATTTCACCAAGTTTCTGATCGACC
GTGAGGGCAATGTGGTGAAGCGTTACGCGCCGCTGACGAAGCCCGAGGCGATTACCGAGGACATCGAAAAGCTGCTGTGA

Upstream 100 bases:

>100_bases
TGCCGGGCCCGACACCGGGCGCTCAAGCGGGATCGGCCATTCGGCCGACTGTACCGGCGCAGCTTTTGGCATAGACTGAC
GGCTTTCACGGGGGGAGCCC

Downstream 100 bases:

>100_bases
GGCCGCGGTACGGCGACGGTGGCTTGGCGTTGCGTCACGGCGGTCTCTACAGGATTGGCGAAAAGAGCCGCGCCACGTGC
ATCAGCACGCGCTTCAGGGC

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTSIYSFSARTLGGEEVSLEQYSGKVLLIVNTASECGFTPQYAGLQKLYETYAARGLAVLGFPCNQFGKQEPGDAAQIGS
FCEKNYGVTFPMFDKVDVNGANAHPLFRYLTGEAPGVLGLEAIKWNFTKFLIDREGNVVKRYAPLTKPEAITEDIEKLL

Sequences:

>Translated_159_residues
MTSIYSFSARTLGGEEVSLEQYSGKVLLIVNTASECGFTPQYAGLQKLYETYAARGLAVLGFPCNQFGKQEPGDAAQIGS
FCEKNYGVTFPMFDKVDVNGANAHPLFRYLTGEAPGVLGLEAIKWNFTKFLIDREGNVVKRYAPLTKPEAITEDIEKLL
>Mature_158_residues
TSIYSFSARTLGGEEVSLEQYSGKVLLIVNTASECGFTPQYAGLQKLYETYAARGLAVLGFPCNQFGKQEPGDAAQIGSF
CEKNYGVTFPMFDKVDVNGANAHPLFRYLTGEAPGVLGLEAIKWNFTKFLIDREGNVVKRYAPLTKPEAITEDIEKLL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=48.0769230769231, Blast_Score=144, Evalue=3e-35,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=48.0769230769231, Blast_Score=144, Evalue=3e-35,
Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=41.875, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI15618997, Length=159, Percent_Identity=44.0251572327044, Blast_Score=133, Evalue=8e-32,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=47.3282442748092, Blast_Score=115, Evalue=1e-26,
Organism=Homo sapiens, GI4557629, Length=178, Percent_Identity=38.2022471910112, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI41406084, Length=182, Percent_Identity=39.010989010989, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI6006001, Length=178, Percent_Identity=35.9550561797753, Blast_Score=103, Evalue=6e-23,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=35.0282485875706, Blast_Score=94, Evalue=3e-20,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=34.8066298342541, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI41406082, Length=70, Percent_Identity=57.1428571428571, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788003, Length=166, Percent_Identity=42.7710843373494, Blast_Score=151, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=45, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=45, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=46.9135802469136, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=41.7721518987342, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17550320, Length=180, Percent_Identity=36.1111111111111, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193209493, Length=180, Percent_Identity=34.4444444444444, Blast_Score=109, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=41.0526315789474, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=52.7777777777778, Blast_Score=76, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=40.7894736842105, Blast_Score=73, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17507603, Length=111, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=53.1645569620253, Blast_Score=193, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=50.9433962264151, Blast_Score=186, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=44.6540880503145, Blast_Score=155, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=50.314465408805, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=50.314465408805, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=50.314465408805, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=44.0251572327044, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17474; Mature: 17343

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIYSFSARTLGGEEVSLEQYSGKVLLIVNTASECGFTPQYAGLQKLYETYAARGLAVL
CCCEECCCCCCCCCCEEEHHHCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCEEEE
GFPCNQFGKQEPGDAAQIGSFCEKNYGVTFPMFDKVDVNGANAHPLFRYLTGEAPGVLGL
ECCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHCCCCCCCEEH
EAIKWNFTKFLIDREGNVVKRYAPLTKPEAITEDIEKLL
HHHHCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHC
>Mature Secondary Structure 
TSIYSFSARTLGGEEVSLEQYSGKVLLIVNTASECGFTPQYAGLQKLYETYAARGLAVL
CCEECCCCCCCCCCEEEHHHCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCEEEE
GFPCNQFGKQEPGDAAQIGSFCEKNYGVTFPMFDKVDVNGANAHPLFRYLTGEAPGVLGL
ECCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHCCCCCCCEEH
EAIKWNFTKFLIDREGNVVKRYAPLTKPEAITEDIEKLL
HHHHCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]