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The map label for this gene is cocE [H]

Identifier: 91784031

GI number: 91784031

Start: 2952595

End: 2954391

Strand: Reverse

Name: cocE [H]

Synonym: Bxe_A1772

Alternate gene names: 91784031

Gene position: 2954391-2952595 (Counterclockwise)

Preceding gene: 91784032

Following gene: 91784030

Centisome position: 60.34

GC content: 60.93

Gene sequence:

>1797_bases
ATGCATTCCAGGCGAATCTTGCTGTGGGTCACTGCCTTGCTGATCGCGTTTGCCCAGCCTTGTCTGGCCGAGCAGGTCGA
TAGCGGCGTTCCCGGCATGATTTTCGACCATGACGTACCGGTCACGATGACCGATGGCGTACAGTTGCGCGTCAACATCT
ATCGTCCCGAAAAGTCCGGCCGATATCCGGTGCTCATGTTGATGGGGCCCTACGGGAAGGATACGAGCATGGCGGATGCG
CCAGCCTATAAGACATCGTGGGGCAAGCTGATCGCGAAATATCCAGACCTCTGCAGGAAATCCTCGTGCCGCTACATCCG
GTTCGAGGCGCCCGATCCCGAGCGGTGGGTGGCCGACGGTTACATCGTCATCCACGCCGACGTTCGCGGGGCCGGCGCAT
CTCCGGGCGTGCTCGACCCCTTCTCGCCGCGGGAGACTGAAGACTACGCCACGCTGATTACCTGGGCGGCCCGGCAGACC
TGGAGTTCGGGAAAGGTCGGTCTGCTCGGCACTTCTTTCCAGGCGATCAATCAGTATCAGGTGGCCGCGTTACAGCCAGA
AGGGCTTGCCGCGATACTGCCCTGGGAAGGCGCGTTCGATCAGTATCGGGAGATCGCATACTATGGTGGCATTCTGAACG
TTGCATGGGAGTTCTGGTGGACCCATCAGGTGGTCCCCAATCAGAACGGCAATGCGCAGACGCCCCTGGTCGATTCGATC
AATGGTGGCACGGATACGGGGGCGCCTCTTGCCCCGGACGTCTTGAAGCAAAACCGCGTCGATCCCGTTGAAGCCTTTGC
GCAGCACCCGTTCGACGACACCTATTATCGGCAGCGCACGCCCGACGCCAGCCAGATCAAGGTCCCGCTGCTCGACGTTG
CGAACTGGACGGACTGGAGTACCGCCGGCTATCGCTTCGCCGCCAGCAAGGGCAAATGGCTGCGGATTCAGACCGGCGAC
CATCTGACGCCTTTCTATTCGGACGAGGCGCTCGCGCTGCAAAAGCGCTTCTTCGATCATTTCCTGAAGGGCGTGGACAA
TGGCTGGGAGAAAGAGCCGCGCGTTGCGGTGCAGATCCGCCGGCCCAACGGGACAGTCTGGAGGAATGCTGGCGCCTGGC
CGCTACCCGGCACACGTTGGCAATGCTACTATCTCGATGCGGCGAACGCTTCGATGGCGCCGGGCCTGGAGCATCTGGCG
TCCGCCCAGAAATCGTACGCCGGACTTGGCGATGAGCTCACTTTCACGACGAAGCCCTTCAGCAAGGAGACGGAATTCAC
CGGCCCGATCGGCGTGAGGTTGTGGGTCGGTTCGTCGACGGCGGATATGGATATCTTCGCGGCCCTCAGGCTGATTGATC
CGCAGGGAAGGGACGTTACCTTTATCGGCAACAGCGATCCGAACGTGCCACTGGATCTCGGATATTTGCGCGTGTCGCAC
CGCGCTGTCGACCGGACGAAATCGACCCTCTACCAGCCTTTCCACCCTCATGTCGCTTCTGAGCCGATGACGCCCGGGCG
GCTCTATCCCGTCGACGTCGAATTTACCGAGCCGACTAGCATCGTCATTCCAAGGGGCTATCGACTTGCGTTAACGATCC
AGGGCAAGGATTTCGGATACGGACCGGATGCGAACATTGTGCACGCTAACGATTACCCCCTTCCCGACGCCCACAACTCA
GGGCTCTTTTTCGCCGCTCATCCGAACCGGGACGCAAAGCTGTATGGCGGAACGAACACGGTCGCGACCGGCAGGGACCA
TGCGTCGTACCTCCTGCTGCCGCGCATTCCGCCTTGA

Upstream 100 bases:

>100_bases
GCGCGATCGGGGCCGCTAAAAGCCAACTTCGCCCAGCGGCGGGTACCGAGCCGGGATGAGGCGGCGCAGTTGCCACACCA
ATAAATCAGGAGTTCTTATC

Downstream 100 bases:

>100_bases
TCATGACGCTGCTGTCGTATGTGACCGTCGCCCTGACGCTGCTCGCGGGCCTCTCTCTCGTGATTTTCGCGGCGGTCACA
GGCGTGCCGACGCTTTCGTC

Product: putative esterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MHSRRILLWVTALLIAFAQPCLAEQVDSGVPGMIFDHDVPVTMTDGVQLRVNIYRPEKSGRYPVLMLMGPYGKDTSMADA
PAYKTSWGKLIAKYPDLCRKSSCRYIRFEAPDPERWVADGYIVIHADVRGAGASPGVLDPFSPRETEDYATLITWAARQT
WSSGKVGLLGTSFQAINQYQVAALQPEGLAAILPWEGAFDQYREIAYYGGILNVAWEFWWTHQVVPNQNGNAQTPLVDSI
NGGTDTGAPLAPDVLKQNRVDPVEAFAQHPFDDTYYRQRTPDASQIKVPLLDVANWTDWSTAGYRFAASKGKWLRIQTGD
HLTPFYSDEALALQKRFFDHFLKGVDNGWEKEPRVAVQIRRPNGTVWRNAGAWPLPGTRWQCYYLDAANASMAPGLEHLA
SAQKSYAGLGDELTFTTKPFSKETEFTGPIGVRLWVGSSTADMDIFAALRLIDPQGRDVTFIGNSDPNVPLDLGYLRVSH
RAVDRTKSTLYQPFHPHVASEPMTPGRLYPVDVEFTEPTSIVIPRGYRLALTIQGKDFGYGPDANIVHANDYPLPDAHNS
GLFFAAHPNRDAKLYGGTNTVATGRDHASYLLLPRIPP

Sequences:

>Translated_598_residues
MHSRRILLWVTALLIAFAQPCLAEQVDSGVPGMIFDHDVPVTMTDGVQLRVNIYRPEKSGRYPVLMLMGPYGKDTSMADA
PAYKTSWGKLIAKYPDLCRKSSCRYIRFEAPDPERWVADGYIVIHADVRGAGASPGVLDPFSPRETEDYATLITWAARQT
WSSGKVGLLGTSFQAINQYQVAALQPEGLAAILPWEGAFDQYREIAYYGGILNVAWEFWWTHQVVPNQNGNAQTPLVDSI
NGGTDTGAPLAPDVLKQNRVDPVEAFAQHPFDDTYYRQRTPDASQIKVPLLDVANWTDWSTAGYRFAASKGKWLRIQTGD
HLTPFYSDEALALQKRFFDHFLKGVDNGWEKEPRVAVQIRRPNGTVWRNAGAWPLPGTRWQCYYLDAANASMAPGLEHLA
SAQKSYAGLGDELTFTTKPFSKETEFTGPIGVRLWVGSSTADMDIFAALRLIDPQGRDVTFIGNSDPNVPLDLGYLRVSH
RAVDRTKSTLYQPFHPHVASEPMTPGRLYPVDVEFTEPTSIVIPRGYRLALTIQGKDFGYGPDANIVHANDYPLPDAHNS
GLFFAAHPNRDAKLYGGTNTVATGRDHASYLLLPRIPP
>Mature_598_residues
MHSRRILLWVTALLIAFAQPCLAEQVDSGVPGMIFDHDVPVTMTDGVQLRVNIYRPEKSGRYPVLMLMGPYGKDTSMADA
PAYKTSWGKLIAKYPDLCRKSSCRYIRFEAPDPERWVADGYIVIHADVRGAGASPGVLDPFSPRETEDYATLITWAARQT
WSSGKVGLLGTSFQAINQYQVAALQPEGLAAILPWEGAFDQYREIAYYGGILNVAWEFWWTHQVVPNQNGNAQTPLVDSI
NGGTDTGAPLAPDVLKQNRVDPVEAFAQHPFDDTYYRQRTPDASQIKVPLLDVANWTDWSTAGYRFAASKGKWLRIQTGD
HLTPFYSDEALALQKRFFDHFLKGVDNGWEKEPRVAVQIRRPNGTVWRNAGAWPLPGTRWQCYYLDAANASMAPGLEHLA
SAQKSYAGLGDELTFTTKPFSKETEFTGPIGVRLWVGSSTADMDIFAALRLIDPQGRDVTFIGNSDPNVPLDLGYLRVSH
RAVDRTKSTLYQPFHPHVASEPMTPGRLYPVDVEFTEPTSIVIPRGYRLALTIQGKDFGYGPDANIVHANDYPLPDAHNS
GLFFAAHPNRDAKLYGGTNTVATGRDHASYLLLPRIPP

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 66447; Mature: 66447

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSRRILLWVTALLIAFAQPCLAEQVDSGVPGMIFDHDVPVTMTDGVQLRVNIYRPEKSG
CCCCEEHHHHHHHHHHHHCHHHHHHHCCCCCCEEEECCCCEEEECCEEEEEEEECCCCCC
RYPVLMLMGPYGKDTSMADAPAYKTSWGKLIAKYPDLCRKSSCRYIRFEAPDPERWVADG
CCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEECC
YIVIHADVRGAGASPGVLDPFSPRETEDYATLITWAARQTWSSGKVGLLGTSFQAINQYQ
EEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHEEHHHHHCCCCCCEEEEECCHHHCCCEE
VAALQPEGLAAILPWEGAFDQYREIAYYGGILNVAWEFWWTHQVVPNQNGNAQTPLVDSI
EEEECCCCCEEEECCCCCHHHHHHHHHHCCHHHEEEEEEEEEEECCCCCCCCCCCEEECC
NGGTDTGAPLAPDVLKQNRVDPVEAFAQHPFDDTYYRQRTPDASQIKVPLLDVANWTDWS
CCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCHHHCCCCCHHHEEEEEEEECCCCCCC
TAGYRFAASKGKWLRIQTGDHLTPFYSDEALALQKRFFDHFLKGVDNGWEKEPRVAVQIR
CCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
RPNGTVWRNAGAWPLPGTRWQCYYLDAANASMAPGLEHLASAQKSYAGLGDELTFTTKPF
CCCCCEEECCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
SKETEFTGPIGVRLWVGSSTADMDIFAALRLIDPQGRDVTFIGNSDPNVPLDLGYLRVSH
CCCCCCCCCEEEEEEECCCCCCHHEEEEEEEECCCCCEEEEECCCCCCCCEEEHEEEEHH
RAVDRTKSTLYQPFHPHVASEPMTPGRLYPVDVEFTEPTSIVIPRGYRLALTIQGKDFGY
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCEEEEEEEECCCCCC
GPDANIVHANDYPLPDAHNSGLFFAAHPNRDAKLYGGTNTVATGRDHASYLLLPRIPP
CCCCCEEECCCCCCCCCCCCCEEEEECCCCCCEEECCCCCEECCCCCCEEEEECCCCC
>Mature Secondary Structure
MHSRRILLWVTALLIAFAQPCLAEQVDSGVPGMIFDHDVPVTMTDGVQLRVNIYRPEKSG
CCCCEEHHHHHHHHHHHHCHHHHHHHCCCCCCEEEECCCCEEEECCEEEEEEEECCCCCC
RYPVLMLMGPYGKDTSMADAPAYKTSWGKLIAKYPDLCRKSSCRYIRFEAPDPERWVADG
CCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEECC
YIVIHADVRGAGASPGVLDPFSPRETEDYATLITWAARQTWSSGKVGLLGTSFQAINQYQ
EEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHEEHHHHHCCCCCCEEEEECCHHHCCCEE
VAALQPEGLAAILPWEGAFDQYREIAYYGGILNVAWEFWWTHQVVPNQNGNAQTPLVDSI
EEEECCCCCEEEECCCCCHHHHHHHHHHCCHHHEEEEEEEEEEECCCCCCCCCCCEEECC
NGGTDTGAPLAPDVLKQNRVDPVEAFAQHPFDDTYYRQRTPDASQIKVPLLDVANWTDWS
CCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCHHHCCCCCHHHEEEEEEEECCCCCCC
TAGYRFAASKGKWLRIQTGDHLTPFYSDEALALQKRFFDHFLKGVDNGWEKEPRVAVQIR
CCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
RPNGTVWRNAGAWPLPGTRWQCYYLDAANASMAPGLEHLASAQKSYAGLGDELTFTTKPF
CCCCCEEECCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
SKETEFTGPIGVRLWVGSSTADMDIFAALRLIDPQGRDVTFIGNSDPNVPLDLGYLRVSH
CCCCCCCCCEEEEEEECCCCCCHHEEEEEEEECCCCCEEEEECCCCCCCCEEEHEEEEHH
RAVDRTKSTLYQPFHPHVASEPMTPGRLYPVDVEFTEPTSIVIPRGYRLALTIQGKDFGY
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCEEEEEEEECCCCCC
GPDANIVHANDYPLPDAHNSGLFFAAHPNRDAKLYGGTNTVATGRDHASYLLLPRIPP
CCCCCEEECCCCCCCCCCCCCEEEEECCCCCCEEECCCCCEECCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]