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The map label for this gene is uvrY [H]

Identifier: 91783961

GI number: 91783961

Start: 2874718

End: 2875368

Strand: Direct

Name: uvrY [H]

Synonym: Bxe_A1850

Alternate gene names: 91783961

Gene position: 2874718-2875368 (Clockwise)

Preceding gene: 91783960

Following gene: 91783962

Centisome position: 58.72

GC content: 63.9

Gene sequence:

>651_bases
ATGACCCGCGTCCTGATTGCCGACGACCACGCGCTGGTGCGCGACGGTCTGCGCCATATCCTCAAGGGCGCAAGCGGCTT
CGAAGTGGTCGGCGAAGCGGACGATAGCGCCAGCACCGTCGCGCTGATCCGCGAGCGGGCCGCCGACGTGCTGGTGCTCG
ACCTGTCCATGCCCGGGCGCAACGGGGTGGAGTTGATCAAGCAGATCAAGGAGGAAAAACCCACGCTGCGCATTCTCGTG
CTGACCATGCACGCCGAACAGCAATATGCGGTGCGCGCGTTCAAGGCCGGTGCGTCCGGTTATCTGACGAAGGAAAGCGC
GAGCGCCGAACTGGTGGCCGCCGTGACCAAAGTCGCGGCCGGCGGTGTCTACGTGAGCCTCGCAATGGCCGAACGGTTCG
CGCAAAGCCTGAACGAACCCGCCGATCTGCTGCCGCATCAGCGTCTGTCCGATCGGGAGTTCGACGTTCTGAAGCGGATT
GCCGCGGGTCAGACCATCACGGAGATCGCGGCCGAGCTGTGTGTGAGCAGCAAGACCGTCAGCACCTACAAGACGCGCAT
CCTGGAGAAAATGCAGATGCCGCACGAGGCCGCCCTCGTGCGCTATGCGATGCGCCACAAACTGGTCAGCGACGAAGAAG
GCGACATCTAG

Upstream 100 bases:

>100_bases
TGCTCGGCGGCGCGGTCGACATTCATACCGCGCATGGCCAGGGCTTTGCGCTCACCGTCACCATTCCGGCAGAAACCGTG
CAGATGCAGGAGATGCAAAC

Downstream 100 bases:

>100_bases
ACGTTTTCCCGGCGCCGCCGCCTGCGCGCCATGCCGCAGGCGGCGGCGCCCGTTTTCTCTCTCCAATCTGCACCACGACC
CACCACCCTTCGCACCCAGG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTRVLIADDHALVRDGLRHILKGASGFEVVGEADDSASTVALIRERAADVLVLDLSMPGRNGVELIKQIKEEKPTLRILV
LTMHAEQQYAVRAFKAGASGYLTKESASAELVAAVTKVAAGGVYVSLAMAERFAQSLNEPADLLPHQRLSDREFDVLKRI
AAGQTITEIAAELCVSSKTVSTYKTRILEKMQMPHEAALVRYAMRHKLVSDEEGDI

Sequences:

>Translated_216_residues
MTRVLIADDHALVRDGLRHILKGASGFEVVGEADDSASTVALIRERAADVLVLDLSMPGRNGVELIKQIKEEKPTLRILV
LTMHAEQQYAVRAFKAGASGYLTKESASAELVAAVTKVAAGGVYVSLAMAERFAQSLNEPADLLPHQRLSDREFDVLKRI
AAGQTITEIAAELCVSSKTVSTYKTRILEKMQMPHEAALVRYAMRHKLVSDEEGDI
>Mature_215_residues
TRVLIADDHALVRDGLRHILKGASGFEVVGEADDSASTVALIRERAADVLVLDLSMPGRNGVELIKQIKEEKPTLRILVL
TMHAEQQYAVRAFKAGASGYLTKESASAELVAAVTKVAAGGVYVSLAMAERFAQSLNEPADLLPHQRLSDREFDVLKRIA
AGQTITEIAAELCVSSKTVSTYKTRILEKMQMPHEAALVRYAMRHKLVSDEEGDI

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=213, Percent_Identity=37.5586854460094, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1786747, Length=211, Percent_Identity=29.8578199052133, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=32.8358208955224, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=34.8717948717949, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1788712, Length=204, Percent_Identity=27.4509803921569, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788546, Length=203, Percent_Identity=33.4975369458128, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=33.5164835164835, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=34.7457627118644, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082052, Length=111, Percent_Identity=34.2342342342342, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=33.8983050847458, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23555; Mature: 23424

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVLIADDHALVRDGLRHILKGASGFEVVGEADDSASTVALIRERAADVLVLDLSMPGR
CCEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCC
NGVELIKQIKEEKPTLRILVLTMHAEQQYAVRAFKAGASGYLTKESASAELVAAVTKVAA
CHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHC
GGVYVSLAMAERFAQSLNEPADLLPHQRLSDREFDVLKRIAAGQTITEIAAELCVSSKTV
CCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHH
STYKTRILEKMQMPHEAALVRYAMRHKLVSDEEGDI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TRVLIADDHALVRDGLRHILKGASGFEVVGEADDSASTVALIRERAADVLVLDLSMPGR
CEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCC
NGVELIKQIKEEKPTLRILVLTMHAEQQYAVRAFKAGASGYLTKESASAELVAAVTKVAA
CHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHC
GGVYVSLAMAERFAQSLNEPADLLPHQRLSDREFDVLKRIAAGQTITEIAAELCVSSKTV
CCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHH
STYKTRILEKMQMPHEAALVRYAMRHKLVSDEEGDI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]