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The map label for this gene is arcB [H]

Identifier: 91783936

GI number: 91783936

Start: 2849287

End: 2850285

Strand: Direct

Name: arcB [H]

Synonym: Bxe_A1876

Alternate gene names: 91783936

Gene position: 2849287-2850285 (Clockwise)

Preceding gene: 91783935

Following gene: 91783937

Centisome position: 58.2

GC content: 62.36

Gene sequence:

>999_bases
ATGGCTTTCAATCTACGCAATCGCAGTCTGCTCAACATGCAGGACTTCGCGCCGCGCGACATCCGCTTTCTGCTCGACCT
CGCCTCCGAGCTGAAGCGCGCCAAGTACGCCGGCAACGAAGTCCCGCGGCTCAACGGCAAGAACGTCGCATTGATTTTCG
AAAAGACCTCGACGCGCACGCGTTGCGCATTCGAGGTCGCCGTGCACGACCAGGGCGGCCACGTCACCTACATCGACTCC
GCGAGTTCGCAGCTCGGCCGCAAGGAGTCGCTCAAGGACACCGCGCGGGTACTCGGACGGCTCTATGACGGTATCGAATA
CCGCGGGTTTCATCAGAGCGTGGTCGAGGATCTCGCGACCTATTCGCATGTTCCGGTCTGGAACGGACTCACCGACGAAT
TCCACCCCACCCAGGTACTCGCCGACCTGCTCACCATGCAGGAATTCGGCGAGAAACCGTTGCACGAGCTATCGTTCTGC
TACCTCGGCGACGCCCGCTTCAACATGGGCAATTCGCTGCTGATCGGCGGGGTGCAAATGGGCATGGACGTGCGCATCGC
GGCGCCGCGCGAATTGTGGCCGCACGACGAACTGGTAGCGCAAATGCGGCTTCTCGCCGAGCGCACCGGCGCCAGCGTGA
CGATCGTCGAGGATCCGCATGAGGCGGTGAGCGGCGTCGACTTCGTCTACACGGATGTCTGGGTGTCGATGGGCGAGCCC
GTCGAAGCGTGGGGCCCGCGAATCGATCTCCTGCGCCCCTATCAGGTCAACGCCGCGCTGATGAAAGCGACCGGCAACCC
GCGCACCCGCTTCATGCACTGCCTGCCCGCCTATCACAATCTCGACACCGACACCGGCCGGATGGTCCACGAGCATTTCG
GCATGTCCGAACTCGAAGTCAGCGACGAGGTGTTCGAATCGGATGCGTCGATCGTCTTTTCCCAGGCTGAGAACCGCATG
CACACGATCAAGGCCGTGCTTGTGGCAACCCTCGCTTGA

Upstream 100 bases:

>100_bases
ACTGGGCCGCGGGCGCGGCGGCGGCCATTGCATGACCTGCCCGATCGAACGCGCCCCCCTCTGACGCGAAGCGCGCGTCG
CACCTTTGGAGAATCCGCTC

Downstream 100 bases:

>100_bases
GGCGCTCACCATGCGCATTCTGATAGCGCTGGGCGGCAACGCGCTGCTGCGCCGCGGCGAACCGATGACGATGGCGCGCC
AGCTCGACAATATCCGCCGT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MAFNLRNRSLLNMQDFAPRDIRFLLDLASELKRAKYAGNEVPRLNGKNVALIFEKTSTRTRCAFEVAVHDQGGHVTYIDS
ASSQLGRKESLKDTARVLGRLYDGIEYRGFHQSVVEDLATYSHVPVWNGLTDEFHPTQVLADLLTMQEFGEKPLHELSFC
YLGDARFNMGNSLLIGGVQMGMDVRIAAPRELWPHDELVAQMRLLAERTGASVTIVEDPHEAVSGVDFVYTDVWVSMGEP
VEAWGPRIDLLRPYQVNAALMKATGNPRTRFMHCLPAYHNLDTDTGRMVHEHFGMSELEVSDEVFESDASIVFSQAENRM
HTIKAVLVATLA

Sequences:

>Translated_332_residues
MAFNLRNRSLLNMQDFAPRDIRFLLDLASELKRAKYAGNEVPRLNGKNVALIFEKTSTRTRCAFEVAVHDQGGHVTYIDS
ASSQLGRKESLKDTARVLGRLYDGIEYRGFHQSVVEDLATYSHVPVWNGLTDEFHPTQVLADLLTMQEFGEKPLHELSFC
YLGDARFNMGNSLLIGGVQMGMDVRIAAPRELWPHDELVAQMRLLAERTGASVTIVEDPHEAVSGVDFVYTDVWVSMGEP
VEAWGPRIDLLRPYQVNAALMKATGNPRTRFMHCLPAYHNLDTDTGRMVHEHFGMSELEVSDEVFESDASIVFSQAENRM
HTIKAVLVATLA
>Mature_331_residues
AFNLRNRSLLNMQDFAPRDIRFLLDLASELKRAKYAGNEVPRLNGKNVALIFEKTSTRTRCAFEVAVHDQGGHVTYIDSA
SSQLGRKESLKDTARVLGRLYDGIEYRGFHQSVVEDLATYSHVPVWNGLTDEFHPTQVLADLLTMQEFGEKPLHELSFCY
LGDARFNMGNSLLIGGVQMGMDVRIAAPRELWPHDELVAQMRLLAERTGASVTIVEDPHEAVSGVDFVYTDVWVSMGEPV
EAWGPRIDLLRPYQVNAALMKATGNPRTRFMHCLPAYHNLDTDTGRMVHEHFGMSELEVSDEVFESDASIVFSQAENRMH
TIKAVLVATLA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=328, Percent_Identity=35.9756097560976, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1790703, Length=328, Percent_Identity=57.9268292682927, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1786469, Length=331, Percent_Identity=57.4018126888217, Blast_Score=393, Evalue=1e-111,
Organism=Escherichia coli, GI2367364, Length=172, Percent_Identity=34.3023255813954, Blast_Score=75, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322373, Length=329, Percent_Identity=30.6990881458967, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322331, Length=164, Percent_Identity=30.4878048780488, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24642586, Length=205, Percent_Identity=29.7560975609756, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37284; Mature: 37153

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFNLRNRSLLNMQDFAPRDIRFLLDLASELKRAKYAGNEVPRLNGKNVALIFEKTSTRT
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
RCAFEVAVHDQGGHVTYIDSASSQLGRKESLKDTARVLGRLYDGIEYRGFHQSVVEDLAT
EEEEEEEEECCCCEEEEEECCHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YSHVPVWNGLTDEFHPTQVLADLLTMQEFGEKPLHELSFCYLGDARFNMGNSLLIGGVQM
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHEEEECCCEECCCCEEEEEEEEE
GMDVRIAAPRELWPHDELVAQMRLLAERTGASVTIVEDPHEAVSGVDFVYTDVWVSMGEP
CCEEEEECCHHCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHCCCHHEEHHHHHHCCCC
VEAWGPRIDLLRPYQVNAALMKATGNPRTRFMHCLPAYHNLDTDTGRMVHEHFGMSELEV
HHHHCCCEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHH
SDEVFESDASIVFSQAENRMHTIKAVLVATLA
HHHHHHCCHHEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFNLRNRSLLNMQDFAPRDIRFLLDLASELKRAKYAGNEVPRLNGKNVALIFEKTSTRT
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
RCAFEVAVHDQGGHVTYIDSASSQLGRKESLKDTARVLGRLYDGIEYRGFHQSVVEDLAT
EEEEEEEEECCCCEEEEEECCHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YSHVPVWNGLTDEFHPTQVLADLLTMQEFGEKPLHELSFCYLGDARFNMGNSLLIGGVQM
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHEEEECCCEECCCCEEEEEEEEE
GMDVRIAAPRELWPHDELVAQMRLLAERTGASVTIVEDPHEAVSGVDFVYTDVWVSMGEP
CCEEEEECCHHCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHCCCHHEEHHHHHHCCCC
VEAWGPRIDLLRPYQVNAALMKATGNPRTRFMHCLPAYHNLDTDTGRMVHEHFGMSELEV
HHHHCCCEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHH
SDEVFESDASIVFSQAENRMHTIKAVLVATLA
HHHHHHCCHHEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3109911; 10984043; 2118516; 7479879 [H]