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The map label for this gene is mdtA [H]

Identifier: 91783844

GI number: 91783844

Start: 2752175

End: 2753359

Strand: Direct

Name: mdtA [H]

Synonym: Bxe_A1968

Alternate gene names: 91783844

Gene position: 2752175-2753359 (Clockwise)

Preceding gene: 91783842

Following gene: 91783845

Centisome position: 56.21

GC content: 69.37

Gene sequence:

>1185_bases
GTGAAGCGTCCCGGTCTCCCCGCATCGCCCGCGATGCGTCCGCAGTTTCATCGGTATTGTCATCCCGCGCGCGTGCGCCG
GGCTGCATTCGTGCTGGTTCTCGCCGGCGTCGTCACGCTGGCCGCGTGTTCGAAGAAGGAAGCGGCGGCGCCCGAACCGC
GCCCGGTAGTCGCCGTCGCCGTGCATGCGGACGGCAGCGCGACGCAGGCGGCCTCGCTGCCCGGCGAGGTTCAGGCTCGC
TATTCGACGCCGCTGTCGTTTCGCGTCGGCGGCAAGATCATCGAGCGGCGCGTGCGCCTCGGCGATGTGGTGAAGAACGG
GCAGATCGTCGCCCGGCTCGATCCGGCGGACGCGCAGAAGAACGCCGCGAGCGCGCAGGCGCAACTCGCCGCCGCCCAGC
ACGCCTTGGTGTATGCGAAGCAGCAGCTCGATCGCGATCAGGCGCAGGCCAAAGAAAACCTGATCGCGCCAGCGCAGCTC
GAACAGACCACGAATGCGTACGCGTCCGCGGTTGCGCAGCGCGATCAGGCCGCGCAGCAGGCCGCGCTCTCGAAAGACCA
GTTGCAGTACACCACGCTCGCCGCCGACCACGCCGGCGTGATCACCGCCGAACAGGCCGACACCGGCCAGAACGTCTCCG
CGGGCCAGGCCGTCTACAACCTCGCCTGGAGCGGCGACATCGACGTGGTGTGCGACGTGCCGGAGAACGCGCTTGCCGCG
CTCTCGGTCGGGCAAACCGCCAGCGTCACGCTCGCCGCGCTGCCGGGGCGCAAGTTCGCCGCGCGCGTGCGCGAACTCTC
GCCCGCCGCCGACCCGCAAAGCCGCACCTATCGCGCCAAACTCACGCTCGACAATCCCGGCCCGGACGTGCGCCTGGGCA
TGACCGCGGATATCGAACTCGCCGCGCAAGCCGGCGCTTCGGCCAGTCAGCACGGTTCGTTCACCGTGCCCGCCACCGCA
CTGTTCCACGACGGCACGCAGCCCGCCGTGTGGATCGTGCGCGCCGCGGACAACGCGCTGGAACTGCGCCGTGTGACGGT
CACGCGCTATAACGAACGCACCATCGTGATCAGTCAGGGCCTCAAGGACGGCGAACGCGTCGTGCTGCAAGGCGTGCATA
CCGTGACCGCCGGCGAAAAAGTCCGTGCGATCGCGCCGCTGCATCCCGAGGACTTCGCTTCATGA

Upstream 100 bases:

>100_bases
AGTCAGATGCGTATGCCAATTGCATGAACGGCCGTCGTGTCTTCGCTGGCGGGCCGCTGCGGCTTGCCGTGTTCGTTCGC
TGTCTCCAGTCGGGGTAAAT

Downstream 100 bases:

>100_bases
GCACCACGCATGAGGAGGGACGCTTCAACCTGTCCGCATGGGCGTTGCGCCACCAGGCGCTGGTCGTTTTCCTGATCGCG
CTCGCGACCGCCTTCGGCAT

Product: multidrug efflux pump, membrane fusion protein CzcB subfamily

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKRPGLPASPAMRPQFHRYCHPARVRRAAFVLVLAGVVTLAACSKKEAAAPEPRPVVAVAVHADGSATQAASLPGEVQAR
YSTPLSFRVGGKIIERRVRLGDVVKNGQIVARLDPADAQKNAASAQAQLAAAQHALVYAKQQLDRDQAQAKENLIAPAQL
EQTTNAYASAVAQRDQAAQQAALSKDQLQYTTLAADHAGVITAEQADTGQNVSAGQAVYNLAWSGDIDVVCDVPENALAA
LSVGQTASVTLAALPGRKFAARVRELSPAADPQSRTYRAKLTLDNPGPDVRLGMTADIELAAQAGASASQHGSFTVPATA
LFHDGTQPAVWIVRAADNALELRRVTVTRYNERTIVISQGLKDGERVVLQGVHTVTAGEKVRAIAPLHPEDFAS

Sequences:

>Translated_394_residues
MKRPGLPASPAMRPQFHRYCHPARVRRAAFVLVLAGVVTLAACSKKEAAAPEPRPVVAVAVHADGSATQAASLPGEVQAR
YSTPLSFRVGGKIIERRVRLGDVVKNGQIVARLDPADAQKNAASAQAQLAAAQHALVYAKQQLDRDQAQAKENLIAPAQL
EQTTNAYASAVAQRDQAAQQAALSKDQLQYTTLAADHAGVITAEQADTGQNVSAGQAVYNLAWSGDIDVVCDVPENALAA
LSVGQTASVTLAALPGRKFAARVRELSPAADPQSRTYRAKLTLDNPGPDVRLGMTADIELAAQAGASASQHGSFTVPATA
LFHDGTQPAVWIVRAADNALELRRVTVTRYNERTIVISQGLKDGERVVLQGVHTVTAGEKVRAIAPLHPEDFAS
>Mature_394_residues
MKRPGLPASPAMRPQFHRYCHPARVRRAAFVLVLAGVVTLAACSKKEAAAPEPRPVVAVAVHADGSATQAASLPGEVQAR
YSTPLSFRVGGKIIERRVRLGDVVKNGQIVARLDPADAQKNAASAQAQLAAAQHALVYAKQQLDRDQAQAKENLIAPAQL
EQTTNAYASAVAQRDQAAQQAALSKDQLQYTTLAADHAGVITAEQADTGQNVSAGQAVYNLAWSGDIDVVCDVPENALAA
LSVGQTASVTLAALPGRKFAARVRELSPAADPQSRTYRAKLTLDNPGPDVRLGMTADIELAAQAGASASQHGSFTVPATA
LFHDGTQPAVWIVRAADNALELRRVTVTRYNERTIVISQGLKDGERVVLQGVHTVTAGEKVRAIAPLHPEDFAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=326, Percent_Identity=25.4601226993865, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789929, Length=383, Percent_Identity=24.8041775456919, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081796, Length=363, Percent_Identity=25.6198347107438, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41562; Mature: 41562

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPGLPASPAMRPQFHRYCHPARVRRAAFVLVLAGVVTLAACSKKEAAAPEPRPVVAVA
CCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
VHADGSATQAASLPGEVQARYSTPLSFRVGGKIIERRVRLGDVVKNGQIVARLDPADAQK
EECCCCCCHHHCCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCHH
NAASAQAQLAAAQHALVYAKQQLDRDQAQAKENLIAPAQLEQTTNAYASAVAQRDQAAQQ
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AALSKDQLQYTTLAADHAGVITAEQADTGQNVSAGQAVYNLAWSGDIDVVCDVPENALAA
HHCCHHHEEEEEEECCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHH
LSVGQTASVTLAALPGRKFAARVRELSPAADPQSRTYRAKLTLDNPGPDVRLGMTADIEL
EECCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECEEE
AAQAGASASQHGSFTVPATALFHDGTQPAVWIVRAADNALELRRVTVTRYNERTIVISQG
HHHCCCCCCCCCCEECCCCEEECCCCCCEEEEEEECCCCEEEEEEEEEEECCEEEEEECC
LKDGERVVLQGVHTVTAGEKVRAIAPLHPEDFAS
CCCCCEEEEECCEEECCCCCEEEECCCCCHHCCC
>Mature Secondary Structure
MKRPGLPASPAMRPQFHRYCHPARVRRAAFVLVLAGVVTLAACSKKEAAAPEPRPVVAVA
CCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
VHADGSATQAASLPGEVQARYSTPLSFRVGGKIIERRVRLGDVVKNGQIVARLDPADAQK
EECCCCCCHHHCCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCHH
NAASAQAQLAAAQHALVYAKQQLDRDQAQAKENLIAPAQLEQTTNAYASAVAQRDQAAQQ
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AALSKDQLQYTTLAADHAGVITAEQADTGQNVSAGQAVYNLAWSGDIDVVCDVPENALAA
HHCCHHHEEEEEEECCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHH
LSVGQTASVTLAALPGRKFAARVRELSPAADPQSRTYRAKLTLDNPGPDVRLGMTADIEL
EECCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECEEE
AAQAGASASQHGSFTVPATALFHDGTQPAVWIVRAADNALELRRVTVTRYNERTIVISQG
HHHCCCCCCCCCCEECCCCEEECCCCCCEEEEEEECCCCEEEEEEEEEEECCEEEEEECC
LKDGERVVLQGVHTVTAGEKVRAIAPLHPEDFAS
CCCCCEEEEECCEEECCCCCEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]