Click here to switch to the map view.

The map label for this gene is corA [H]

Identifier: 91783816

GI number: 91783816

Start: 2724027

End: 2725004

Strand: Reverse

Name: corA [H]

Synonym: Bxe_A1996

Alternate gene names: 91783816

Gene position: 2725004-2724027 (Counterclockwise)

Preceding gene: 91783817

Following gene: 91783815

Centisome position: 55.66

GC content: 61.86

Gene sequence:

>978_bases
ATGCTGATCAATTGCGCCGCCTATCAGGACGGCCGGAAGCTGGCAGACATCGATATCGATAGCATCAGCGACTACGTGGC
GCGGCCCGAGTGTTTCGTCTGGGTGGCGCTGATGGACCCGGGCCCGGGCGAACTGGCCGTGATGAAACACGAGTTCGGCC
TGCACGAACTGGCGATCGAAGACGCGCAGAACGGCCACCAGCGTCCCAAGATCGAGGAGTACGGCGAGTCGCTGTTCGCC
GTGATGCACACGGTGGAGATGGACGAACACGGCGAACTGCTGATCGGGGAAGTGGACGTATTCGTGGGCAGCAACTATGT
GCTTTCGGTGCGGCGCGGTACGCGCACCGGCTTCAGGAACGTGCGCGCGCGCTGCGAGCGCGAGCCGCAATTGCTCAAGG
AAGGCTCGGCGTTCGTGCTGTATGCGCTCGCCGACGATATCGTCGACCGGTATTTCCCGATCATCGAGGCGCTGAACAGC
GAGATCGAGGAGATCGAAGACCGGATCTTCGACCGCAACAATTCCGCGGCCTCGCGCGCGATCATCCAGGATCTCTACTC
GTTAAAGCGCCGTCTCGTGATCCTGCAGCACCATATCGCACCGCTGCAGGAAGCCATCAGCAAACTGACGGGCGGCCGCA
TTCCGAGCGTCTGCGAGGGCATGCAGGCGTACTTCCGCGACGTCTACGACCATCTCGAACGGATCGTCAGAATCATCGAC
GGACGGCGCGAAATGGTGGTGACCGCCGTGCAGGTCAATCTCGGCATGATTTCGCTCGCCGAGAGCGAGGTGACCAAACG
GCTCGGCTCGTTCGCGGCGCTGTTCGCGGTGCCGACCATGATCGCCGGCATCTACGGGATGAACTTCGAGAGCATTCCCG
AGTTGCACTACAAGTACGGCTACCCGATCTGTCTGGCGGTCATGCTGACCGTCGACCTCGTGCTGTACTGGCGGTTCCGC
AAGGTCGGCTGGCTCTGA

Upstream 100 bases:

>100_bases
ACATGGCGGCTAACGCAAATCTGTCCATGCAGACCGGCTGCCTGGCTTACGCGTCGTAAGCGTGTGGCCGGTCTGTTTTC
GTTTTGAAGGTAATCCAAAC

Downstream 100 bases:

>100_bases
CGGTCGGGCACGGCATCGTGCCGCGTTATCCGGGCTTGCATCGCGCGCAATAAAAGTCCAGCATAGGCGGCCCGTCGGCC
TGTGATCTTGCGGCTGACGG

Product: magnesium/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLINCAAYQDGRKLADIDIDSISDYVARPECFVWVALMDPGPGELAVMKHEFGLHELAIEDAQNGHQRPKIEEYGESLFA
VMHTVEMDEHGELLIGEVDVFVGSNYVLSVRRGTRTGFRNVRARCEREPQLLKEGSAFVLYALADDIVDRYFPIIEALNS
EIEEIEDRIFDRNNSAASRAIIQDLYSLKRRLVILQHHIAPLQEAISKLTGGRIPSVCEGMQAYFRDVYDHLERIVRIID
GRREMVVTAVQVNLGMISLAESEVTKRLGSFAALFAVPTMIAGIYGMNFESIPELHYKYGYPICLAVMLTVDLVLYWRFR
KVGWL

Sequences:

>Translated_325_residues
MLINCAAYQDGRKLADIDIDSISDYVARPECFVWVALMDPGPGELAVMKHEFGLHELAIEDAQNGHQRPKIEEYGESLFA
VMHTVEMDEHGELLIGEVDVFVGSNYVLSVRRGTRTGFRNVRARCEREPQLLKEGSAFVLYALADDIVDRYFPIIEALNS
EIEEIEDRIFDRNNSAASRAIIQDLYSLKRRLVILQHHIAPLQEAISKLTGGRIPSVCEGMQAYFRDVYDHLERIVRIID
GRREMVVTAVQVNLGMISLAESEVTKRLGSFAALFAVPTMIAGIYGMNFESIPELHYKYGYPICLAVMLTVDLVLYWRFR
KVGWL
>Mature_325_residues
MLINCAAYQDGRKLADIDIDSISDYVARPECFVWVALMDPGPGELAVMKHEFGLHELAIEDAQNGHQRPKIEEYGESLFA
VMHTVEMDEHGELLIGEVDVFVGSNYVLSVRRGTRTGFRNVRARCEREPQLLKEGSAFVLYALADDIVDRYFPIIEALNS
EIEEIEDRIFDRNNSAASRAIIQDLYSLKRRLVILQHHIAPLQEAISKLTGGRIPSVCEGMQAYFRDVYDHLERIVRIID
GRREMVVTAVQVNLGMISLAESEVTKRLGSFAALFAVPTMIAGIYGMNFESIPELHYKYGYPICLAVMLTVDLVLYWRFR
KVGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=310, Percent_Identity=22.5806451612903, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787604, Length=273, Percent_Identity=23.0769230769231, Blast_Score=68, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324442, Length=139, Percent_Identity=30.2158273381295, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321058, Length=139, Percent_Identity=28.7769784172662, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36905; Mature: 36905

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINCAAYQDGRKLADIDIDSISDYVARPECFVWVALMDPGPGELAVMKHEFGLHELAIE
CEEEEEECCCCCEEECCCHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEHHCCHHHHHHH
DAQNGHQRPKIEEYGESLFAVMHTVEMDEHGELLIGEVDVFVGSNYVLSVRRGTRTGFRN
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCEEEEEECCCHHHHHH
VRARCEREPQLLKEGSAFVLYALADDIVDRYFPIIEALNSEIEEIEDRIFDRNNSAASRA
HHHHHCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IIQDLYSLKRRLVILQHHIAPLQEAISKLTGGRIPSVCEGMQAYFRDVYDHLERIVRIID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GRREMVVTAVQVNLGMISLAESEVTKRLGSFAALFAVPTMIAGIYGMNFESIPELHYKYG
CCHHHEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHCC
YPICLAVMLTVDLVLYWRFRKVGWL
CHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLINCAAYQDGRKLADIDIDSISDYVARPECFVWVALMDPGPGELAVMKHEFGLHELAIE
CEEEEEECCCCCEEECCCHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEHHCCHHHHHHH
DAQNGHQRPKIEEYGESLFAVMHTVEMDEHGELLIGEVDVFVGSNYVLSVRRGTRTGFRN
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCEEEEEECCCHHHHHH
VRARCEREPQLLKEGSAFVLYALADDIVDRYFPIIEALNSEIEEIEDRIFDRNNSAASRA
HHHHHCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IIQDLYSLKRRLVILQHHIAPLQEAISKLTGGRIPSVCEGMQAYFRDVYDHLERIVRIID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GRREMVVTAVQVNLGMISLAESEVTKRLGSFAALFAVPTMIAGIYGMNFESIPELHYKYG
CCHHHEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHCC
YPICLAVMLTVDLVLYWRFRKVGWL
CHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]