Click here to switch to the map view.

The map label for this gene is caiD [C]

Identifier: 91783737

GI number: 91783737

Start: 2634716

End: 2635534

Strand: Reverse

Name: caiD [C]

Synonym: Bxe_A2077

Alternate gene names: 91783737

Gene position: 2635534-2634716 (Counterclockwise)

Preceding gene: 91783738

Following gene: 91783736

Centisome position: 53.83

GC content: 66.06

Gene sequence:

>819_bases
ATGACGCAACTCTCGACCGACCTGCGCCATCACGGCCAGAGCCTGCTGCAGGATCTCGACGGCTTTTCCATCGAGATCGA
CGCCGCGCGCGAGCGGGCCGACATCATCCTGCACCGGCCGCCGCTGAACGTGATTTCGATGCATGCACGCGACCAGTTGC
GCGCCGCCTTCGAAGCACTCGACGACGACCCGCGCGTGCGCGTGATCGTGGTGCGCGCCCAGGGCGAGCACTTTTCGAGC
GGCGGCGACATCAAGGGCTTTCTCGAAGCGTCGCCGGAACATGTGTCGAAGCTCGCCTGGAATATCGCCGCGCCCGCGCG
CTGCTCGAAGCCGGTGATCGCCGCCAATCGCGGCTTCTGCTTCGGGGTGGGCTTCGAACTGTCGCTCGCGTGCGATTTCC
GCATTGCCACCGACACCACCTTCTACGCGCTGCCGGAACAGAAACTCGGGCAGATTCCGGGCTCGGGCGGCTCGGCGCGC
TTGCAGCAGATGGTCGGCATCGGCCGCACCAAGGACATCGTGATGCGCTCGCGCCGCATTCCGGGCAAGCAGGCCTACGA
GTGGGGCATCGCGGTCGAATGCGTGGCCGACGCCGAACTCGAAGCGACGACCGACGCGCTGGTGGACGAACTGCGCGCGT
TCTCGCCGCTTGCCCAGCGCACCGCGAAAAAGCTCCTCAACGACACCGAAGACGCGCCGTTGTCGATCGCGATCGAACTC
GAAGGGCACTGCTATAGCCGTCTGCGCACGTCCGACGATTTCCGCGAAGGCGTCGAGGCCTTTCACGGCAAACGCAAGCC
GGTGTTCCGCGGCAGCTAG

Upstream 100 bases:

>100_bases
GGCAAGATTTTGCGCCGCAAGCTCTCAGCCGGCGAATACGAGCCCGACCGGCGCGGCGAATCCCATGCAAACCACACCGA
AACCACCAAGGAGTAACTCC

Downstream 100 bases:

>100_bases
CGCGAGCGCCGCCCGGCGGGCGGCCGCCGACGCCAGATAACCACCAGAAGAGCACGCGAAAAGAACGTGCCTCGAAAACG
GGCACGGTCGAAAGACGGCC

Product: putative enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTQLSTDLRHHGQSLLQDLDGFSIEIDAARERADIILHRPPLNVISMHARDQLRAAFEALDDDPRVRVIVVRAQGEHFSS
GGDIKGFLEASPEHVSKLAWNIAAPARCSKPVIAANRGFCFGVGFELSLACDFRIATDTTFYALPEQKLGQIPGSGGSAR
LQQMVGIGRTKDIVMRSRRIPGKQAYEWGIAVECVADAELEATTDALVDELRAFSPLAQRTAKKLLNDTEDAPLSIAIEL
EGHCYSRLRTSDDFREGVEAFHGKRKPVFRGS

Sequences:

>Translated_272_residues
MTQLSTDLRHHGQSLLQDLDGFSIEIDAARERADIILHRPPLNVISMHARDQLRAAFEALDDDPRVRVIVVRAQGEHFSS
GGDIKGFLEASPEHVSKLAWNIAAPARCSKPVIAANRGFCFGVGFELSLACDFRIATDTTFYALPEQKLGQIPGSGGSAR
LQQMVGIGRTKDIVMRSRRIPGKQAYEWGIAVECVADAELEATTDALVDELRAFSPLAQRTAKKLLNDTEDAPLSIAIEL
EGHCYSRLRTSDDFREGVEAFHGKRKPVFRGS
>Mature_271_residues
TQLSTDLRHHGQSLLQDLDGFSIEIDAARERADIILHRPPLNVISMHARDQLRAAFEALDDDPRVRVIVVRAQGEHFSSG
GDIKGFLEASPEHVSKLAWNIAAPARCSKPVIAANRGFCFGVGFELSLACDFRIATDTTFYALPEQKLGQIPGSGGSARL
QQMVGIGRTKDIVMRSRRIPGKQAYEWGIAVECVADAELEATTDALVDELRAFSPLAQRTAKKLLNDTEDAPLSIAIELE
GHCYSRLRTSDDFREGVEAFHGKRKPVFRGS

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=239, Percent_Identity=30.5439330543933, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI4502327, Length=238, Percent_Identity=32.7731092436975, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI68989263, Length=170, Percent_Identity=32.9411764705882, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI37594471, Length=205, Percent_Identity=29.2682926829268, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI37594469, Length=205, Percent_Identity=29.2682926829268, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20127408, Length=154, Percent_Identity=29.2207792207792, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI150378541, Length=244, Percent_Identity=24.1803278688525, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI70995211, Length=287, Percent_Identity=22.6480836236934, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI221142681, Length=246, Percent_Identity=34.9593495934959, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1787659, Length=243, Percent_Identity=30.4526748971193, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788597, Length=250, Percent_Identity=29.6, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=31.7708333333333, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787660, Length=247, Percent_Identity=29.1497975708502, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790281, Length=177, Percent_Identity=29.9435028248588, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082183, Length=237, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=30.6451612903226, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17540714, Length=204, Percent_Identity=30.3921568627451, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17554946, Length=250, Percent_Identity=29.2, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=254, Percent_Identity=25.9842519685039, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=261, Percent_Identity=23.7547892720307, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=232, Percent_Identity=27.5862068965517, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17558304, Length=156, Percent_Identity=32.0512820512821, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=153, Percent_Identity=28.1045751633987, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25144276, Length=141, Percent_Identity=31.2056737588652, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=141, Percent_Identity=31.2056737588652, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=141, Percent_Identity=31.2056737588652, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24653139, Length=260, Percent_Identity=31.5384615384615, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI20129971, Length=238, Percent_Identity=27.7310924369748, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24653477, Length=238, Percent_Identity=27.7310924369748, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19920382, Length=253, Percent_Identity=27.6679841897233, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21357171, Length=251, Percent_Identity=26.2948207171315, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24654903, Length=198, Percent_Identity=24.7474747474747, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29939; Mature: 29808

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLSTDLRHHGQSLLQDLDGFSIEIDAARERADIILHRPPLNVISMHARDQLRAAFEAL
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCCEEHHHHHHHHHHHHHC
DDDPRVRVIVVRAQGEHFSSGGDIKGFLEASPEHVSKLAWNIAAPARCSKPVIAANRGFC
CCCCCEEEEEEEECCCCCCCCCCEEEHCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCEE
FGVGFELSLACDFRIATDTTFYALPEQKLGQIPGSGGSARLQQMVGIGRTKDIVMRSRRI
EEECEEEEEEEEEEEECCCEEEECCHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCC
PGKQAYEWGIAVECVADAELEATTDALVDELRAFSPLAQRTAKKLLNDTEDAPLSIAIEL
CCCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEE
EGHCYSRLRTSDDFREGVEAFHGKRKPVFRGS
CCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TQLSTDLRHHGQSLLQDLDGFSIEIDAARERADIILHRPPLNVISMHARDQLRAAFEAL
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCCEEHHHHHHHHHHHHHC
DDDPRVRVIVVRAQGEHFSSGGDIKGFLEASPEHVSKLAWNIAAPARCSKPVIAANRGFC
CCCCCEEEEEEEECCCCCCCCCCEEEHCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCEE
FGVGFELSLACDFRIATDTTFYALPEQKLGQIPGSGGSARLQQMVGIGRTKDIVMRSRRI
EEECEEEEEEEEEEEECCCEEEECCHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCC
PGKQAYEWGIAVECVADAELEATTDALVDELRAFSPLAQRTAKKLLNDTEDAPLSIAIEL
CCCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEE
EGHCYSRLRTSDDFREGVEAFHGKRKPVFRGS
CCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA