| Definition | Burkholderia xenovorans LB400 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007951 |
| Length | 4,895,836 |
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The map label for this gene is mrcA [H]
Identifier: 91783618
GI number: 91783618
Start: 2489734
End: 2492250
Strand: Direct
Name: mrcA [H]
Synonym: Bxe_A2197
Alternate gene names: 91783618
Gene position: 2489734-2492250 (Clockwise)
Preceding gene: 91783616
Following gene: 91783620
Centisome position: 50.85
GC content: 68.06
Gene sequence:
>2517_bases GTGAAGCGCCTGATCCCCTCATTGCTGGAGACCCTTGAAAAAGGGCTGACCCTGGCGAACCCGCTGATCGCCCAGGCCCT GTGGCACTTGCGCCATCCGACCCGGCGCGGCGTGCTGAAGGCCTGCGCCGCGCTTCCGCTGCTGTTCGTCCTGTATGTGC TGATCCTGATTCCGTTCACGCCGGGCATCGGCGACATCCGCAAGGCCAAGGTCGAGCAGCCGGCGCAGATCCTGTCGGCG GACGGCAAGCTGCTGGCGGAATTCAAGCCCTCCAACCGCGAGTGGGTCAAACTCAGGGACATCTCGCCGAACGTGGTAAA CGCGCTGATCGCCACCGAAGATCACCGTTTCTACCAGCATTGGGGCCTCGACTGGCGGCGCACCGCCTCGGCCGCGCTGC ATACGTTTTCCGGCGACCGGCAGGGCGGCTCGACCATCACCCAGCAGCTCGCCCGCAATCTTTATCCCGACGAGATCGGC CGCGCGCCGACGCTCACGCGCAAGCTCAAGGAAGCGATCACCGCCTTCAAGATCGAGGCGCTCTACACCAAGGACGAGAT TCTCGAGACTTACCTGAACACGGTGCCGTTCCTCTATAACGCGTACGGCATCGAGATGGCGGCCCGCACCTATTTCGACA AATCGGCCTCCGATCTGACCGTGCTGGAAAGCGCCACGCTCACCGGCATGCTGAAAGGCAATAGCTACTACAACCCGGTG CTGAACCCCGAACGCGCGTTGCAGCGGCGCAATACGGTGCTCGGCCAGATGGTCAAGTACGGCAAGCTGACGCCGGCGGC CTACGCCACGCTCAGCCGCAAACCGCTGCGCATCGATTTCGAGCGCCAGACCGAGCCGCCGGGTCCGGCGCCGCACTTCG CGCAGCAATTGCGCAAGTGGCTGGCGTCATGGGCGGATCGCAACGACTACAACATGTACGCCGACGGGTTGGTGGTGCGC ACCACCATCGATTCGCGTCTGCAGACTATGGCCACCCAGGCGGTCACCTTGCAGGGCAACCAGTTGCAGGGCATCGCCAA CTCGGTGTGGGGCACGCGCGCGGGCTGCTCGAACGGGCGCGACCTGCTGCAGACTTTTCTGCGCGAAACGCCGGATTACC GCGCCGCCAAAGACGCGGGCCTGAGCGACGACGACGCGCTCAAGCGCGTCTCGTCCGACCGCGAGCTCGTAAAGTCGCTG TGCGAATCCAAGACGCGCGTGCAGGCGGACTTTCTGGCAATGGACCCGCGCAACGGCCAGATCCGGGCATGGGTGGGCAG CCGCGACTTCAGCCAGGATCCGTTCGACCACGTCCAGCAGGCGCGGCGCCAGCCGGGTTCGACCTTCAAGCCGTTCGTCT ACGCGGCCGCGTTCGAGGCGGGCGCCAAGCCTACCGATACCTTCGTGGACAAGCCCGTGGAGATCCCGCTGGCAGGCGGC GAAGTCTGGCGTCCGGGCGACGAGGACGAGCCGAGCGATCGCAAGATCAGCCTGCGCGACGGCCTCGCGTATTCGCGCAA CCGGATCACCGCGCAGTTGATGGAAACGGTCGGGCCGAACAAGGTCGCGCGCCTCGCCCGCGCGATGGGCGTGCGCGACA GCGAGCTGGACCCGGTGCCGTCGCTCGCGCTCGGCACGAGCCCCGTCACGCTGAAGGAGATGGTCTCGGCCTACGGCACG ATCGCCAATCTGGGCGGCTACGTGGAACCGGTGATGGTCACGCGTATCGAGGACCGCAAGGGCGACGTGCTGGCCGAGTT CGCGCCGGTGCCGCCCAAACAGGAACTCTCCGCCGATGCCGACCGGATGCTCATCGACGTCATGCGCGACGTGGTGAACC GCGGCACGGGGTCGAGCATTCGCAGCCGCTTCGGCGTGCGCGGCGACGTCGCCGGCAAGACGGGGACGACGCAGGGCAAT GCGGACGGCTGGTTCATCCTGATCCATCCGCAACTCGTGGCGGGCGCGTGGGTCGGCTTCAACGACAGCCGCGTGACCTT GCGCAGCGACTATTGGGGGCAGGGGGCGCACAGCGCGCTGCCGATCGTCGGCGATTTCTTCCAGCGCGCGCAGCGCTCGA GGCTGATCGATACGCGCGTCAAGTTCGCGACCGACCAGGAGCCGGGGTGGTTTGCCGAGCGTTCGGCCAGGTTGCGCGCG TGGTTCGGGAACCTGTTCGCGTCGTCGCCGCCGGCCAGGCCGGAGGCGCCGGTTGCGCCGCGCGGTACGACGCGGCGCGC GCCGGCTAGTGCTCCTGCGGTGCCCGTGGAGCCGTCGGCGTCCGCTACGTTGGCGGAGCCGCGTGACATCCCGCAACCGC CGTTGCTTCAGGCGCCGGGGTCCGCGCCGGGTTCAGCGCCGGCAGCAGCGAGCGGGGCGGTCGACGGTGAAGCGCGCGGC GGCGGCGAGCCGGCGTTGGCGCCGACGCCCACGCCCGACGATGTGGTGCCGCCGGACGCCGGCAGCCCGGCCAACGCGTT GCCGGGAACGTCGACGAACGGCGGCAGCTCGCCTTGA
Upstream 100 bases:
>100_bases GCGGCTTGCGCCGCGCCCACAACGCTCCGTGACTACAAAAATCGGCCGCCGCCGCGCATCTTGGTAGGATTGCGCCTTTC CAAGCCGACTACGAGCTAGT
Downstream 100 bases:
>100_bases GGTGCGAAGCTGGCACGATGTCGACGCAGAGCCGGCGCCGAGGTCCGATTGCGGACGTTTTTGCGCCGCACGCCGTGCTC GTCACGTCCACGGAATGTGC
Product: putative penicillin-binding 1 (peptidoglycansynthetase) transmembrane protein, MrcA
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 838; Mature: 838
Protein sequence:
>838_residues MKRLIPSLLETLEKGLTLANPLIAQALWHLRHPTRRGVLKACAALPLLFVLYVLILIPFTPGIGDIRKAKVEQPAQILSA DGKLLAEFKPSNREWVKLRDISPNVVNALIATEDHRFYQHWGLDWRRTASAALHTFSGDRQGGSTITQQLARNLYPDEIG RAPTLTRKLKEAITAFKIEALYTKDEILETYLNTVPFLYNAYGIEMAARTYFDKSASDLTVLESATLTGMLKGNSYYNPV LNPERALQRRNTVLGQMVKYGKLTPAAYATLSRKPLRIDFERQTEPPGPAPHFAQQLRKWLASWADRNDYNMYADGLVVR TTIDSRLQTMATQAVTLQGNQLQGIANSVWGTRAGCSNGRDLLQTFLRETPDYRAAKDAGLSDDDALKRVSSDRELVKSL CESKTRVQADFLAMDPRNGQIRAWVGSRDFSQDPFDHVQQARRQPGSTFKPFVYAAAFEAGAKPTDTFVDKPVEIPLAGG EVWRPGDEDEPSDRKISLRDGLAYSRNRITAQLMETVGPNKVARLARAMGVRDSELDPVPSLALGTSPVTLKEMVSAYGT IANLGGYVEPVMVTRIEDRKGDVLAEFAPVPPKQELSADADRMLIDVMRDVVNRGTGSSIRSRFGVRGDVAGKTGTTQGN ADGWFILIHPQLVAGAWVGFNDSRVTLRSDYWGQGAHSALPIVGDFFQRAQRSRLIDTRVKFATDQEPGWFAERSARLRA WFGNLFASSPPARPEAPVAPRGTTRRAPASAPAVPVEPSASATLAEPRDIPQPPLLQAPGSAPGSAPAAASGAVDGEARG GGEPALAPTPTPDDVVPPDAGSPANALPGTSTNGGSSP
Sequences:
>Translated_838_residues MKRLIPSLLETLEKGLTLANPLIAQALWHLRHPTRRGVLKACAALPLLFVLYVLILIPFTPGIGDIRKAKVEQPAQILSA DGKLLAEFKPSNREWVKLRDISPNVVNALIATEDHRFYQHWGLDWRRTASAALHTFSGDRQGGSTITQQLARNLYPDEIG RAPTLTRKLKEAITAFKIEALYTKDEILETYLNTVPFLYNAYGIEMAARTYFDKSASDLTVLESATLTGMLKGNSYYNPV LNPERALQRRNTVLGQMVKYGKLTPAAYATLSRKPLRIDFERQTEPPGPAPHFAQQLRKWLASWADRNDYNMYADGLVVR TTIDSRLQTMATQAVTLQGNQLQGIANSVWGTRAGCSNGRDLLQTFLRETPDYRAAKDAGLSDDDALKRVSSDRELVKSL CESKTRVQADFLAMDPRNGQIRAWVGSRDFSQDPFDHVQQARRQPGSTFKPFVYAAAFEAGAKPTDTFVDKPVEIPLAGG EVWRPGDEDEPSDRKISLRDGLAYSRNRITAQLMETVGPNKVARLARAMGVRDSELDPVPSLALGTSPVTLKEMVSAYGT IANLGGYVEPVMVTRIEDRKGDVLAEFAPVPPKQELSADADRMLIDVMRDVVNRGTGSSIRSRFGVRGDVAGKTGTTQGN ADGWFILIHPQLVAGAWVGFNDSRVTLRSDYWGQGAHSALPIVGDFFQRAQRSRLIDTRVKFATDQEPGWFAERSARLRA WFGNLFASSPPARPEAPVAPRGTTRRAPASAPAVPVEPSASATLAEPRDIPQPPLLQAPGSAPGSAPAAASGAVDGEARG GGEPALAPTPTPDDVVPPDAGSPANALPGTSTNGGSSP >Mature_838_residues MKRLIPSLLETLEKGLTLANPLIAQALWHLRHPTRRGVLKACAALPLLFVLYVLILIPFTPGIGDIRKAKVEQPAQILSA DGKLLAEFKPSNREWVKLRDISPNVVNALIATEDHRFYQHWGLDWRRTASAALHTFSGDRQGGSTITQQLARNLYPDEIG RAPTLTRKLKEAITAFKIEALYTKDEILETYLNTVPFLYNAYGIEMAARTYFDKSASDLTVLESATLTGMLKGNSYYNPV LNPERALQRRNTVLGQMVKYGKLTPAAYATLSRKPLRIDFERQTEPPGPAPHFAQQLRKWLASWADRNDYNMYADGLVVR TTIDSRLQTMATQAVTLQGNQLQGIANSVWGTRAGCSNGRDLLQTFLRETPDYRAAKDAGLSDDDALKRVSSDRELVKSL CESKTRVQADFLAMDPRNGQIRAWVGSRDFSQDPFDHVQQARRQPGSTFKPFVYAAAFEAGAKPTDTFVDKPVEIPLAGG EVWRPGDEDEPSDRKISLRDGLAYSRNRITAQLMETVGPNKVARLARAMGVRDSELDPVPSLALGTSPVTLKEMVSAYGT IANLGGYVEPVMVTRIEDRKGDVLAEFAPVPPKQELSADADRMLIDVMRDVVNRGTGSSIRSRFGVRGDVAGKTGTTQGN ADGWFILIHPQLVAGAWVGFNDSRVTLRSDYWGQGAHSALPIVGDFFQRAQRSRLIDTRVKFATDQEPGWFAERSARLRA WFGNLFASSPPARPEAPVAPRGTTRRAPASAPAVPVEPSASATLAEPRDIPQPPLLQAPGSAPGSAPAAASGAVDGEARG GGEPALAPTPTPDDVVPPDAGSPANALPGTSTNGGSSP
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=350, Percent_Identity=36.5714285714286, Blast_Score=185, Evalue=9e-48, Organism=Escherichia coli, GI1786343, Length=589, Percent_Identity=29.8811544991511, Blast_Score=183, Evalue=3e-47, Organism=Escherichia coli, GI1788867, Length=234, Percent_Identity=32.9059829059829, Blast_Score=97, Evalue=6e-21, Organism=Escherichia coli, GI1789601, Length=174, Percent_Identity=36.7816091954023, Blast_Score=89, Evalue=9e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.- [C]
Molecular weight: Translated: 91270; Mature: 91270
Theoretical pI: Translated: 9.48; Mature: 9.48
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRLIPSLLETLEKGLTLANPLIAQALWHLRHPTRRGVLKACAALPLLFVLYVLILIPFT CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC PGIGDIRKAKVEQPAQILSADGKLLAEFKPSNREWVKLRDISPNVVNALIATEDHRFYQH CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHCCCCHHHHH WGLDWRRTASAALHTFSGDRQGGSTITQQLARNLYPDEIGRAPTLTRKLKEAITAFKIEA HCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHH LYTKDEILETYLNTVPFLYNAYGIEMAARTYFDKSASDLTVLESATLTGMLKGNSYYNPV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHEEEEECCCCCCCCC LNPERALQRRNTVLGQMVKYGKLTPAAYATLSRKPLRIDFERQTEPPGPAPHFAQQLRKW CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEHHCCCCCCCCCHHHHHHHHHH LASWADRNDYNMYADGLVVRTTIDSRLQTMATQAVTLQGNQLQGIANSVWGTRAGCSNGR HHHHCCCCCCCEEECCEEEEEHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCCCCCCCH DLLQTFLRETPDYRAAKDAGLSDDDALKRVSSDRELVKSLCESKTRVQADFLAMDPRNGQ HHHHHHHHCCCCCCHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHEEEHHEEECCCCCE IRAWVGSRDFSQDPFDHVQQARRQPGSTFKPFVYAAAFEAGAKPTDTFVDKPVEIPLAGG EEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCEEEECCC EVWRPGDEDEPSDRKISLRDGLAYSRNRITAQLMETVGPNKVARLARAMGVRDSELDPVP CCCCCCCCCCCCCCEEEHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC SLALGTSPVTLKEMVSAYGTIANLGGYVEPVMVTRIEDRKGDVLAEFAPVPPKQELSADA CHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHCCCCCCHHHHCCHH DRMLIDVMRDVVNRGTGSSIRSRFGVRGDVAGKTGTTQGNADGWFILIHPQLVAGAWVGF HHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHEEECC NDSRVTLRSDYWGQGAHSALPIVGDFFQRAQRSRLIDTRVKFATDQEPGWFAERSARLRA CCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH WFGNLFASSPPARPEAPVAPRGTTRRAPASAPAVPVEPSASATLAEPRDIPQPPLLQAPG HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC SAPGSAPAAASGAVDGEARGGGEPALAPTPTPDDVVPPDAGSPANALPGTSTNGGSSP CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MKRLIPSLLETLEKGLTLANPLIAQALWHLRHPTRRGVLKACAALPLLFVLYVLILIPFT CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC PGIGDIRKAKVEQPAQILSADGKLLAEFKPSNREWVKLRDISPNVVNALIATEDHRFYQH CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHCCCCHHHHH WGLDWRRTASAALHTFSGDRQGGSTITQQLARNLYPDEIGRAPTLTRKLKEAITAFKIEA HCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHH LYTKDEILETYLNTVPFLYNAYGIEMAARTYFDKSASDLTVLESATLTGMLKGNSYYNPV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHEEEEECCCCCCCCC LNPERALQRRNTVLGQMVKYGKLTPAAYATLSRKPLRIDFERQTEPPGPAPHFAQQLRKW CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEHHCCCCCCCCCHHHHHHHHHH LASWADRNDYNMYADGLVVRTTIDSRLQTMATQAVTLQGNQLQGIANSVWGTRAGCSNGR HHHHCCCCCCCEEECCEEEEEHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCCCCCCCH DLLQTFLRETPDYRAAKDAGLSDDDALKRVSSDRELVKSLCESKTRVQADFLAMDPRNGQ HHHHHHHHCCCCCCHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHEEEHHEEECCCCCE IRAWVGSRDFSQDPFDHVQQARRQPGSTFKPFVYAAAFEAGAKPTDTFVDKPVEIPLAGG EEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCEEEECCC EVWRPGDEDEPSDRKISLRDGLAYSRNRITAQLMETVGPNKVARLARAMGVRDSELDPVP CCCCCCCCCCCCCCEEEHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC SLALGTSPVTLKEMVSAYGTIANLGGYVEPVMVTRIEDRKGDVLAEFAPVPPKQELSADA CHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHCCCCCCHHHHCCHH DRMLIDVMRDVVNRGTGSSIRSRFGVRGDVAGKTGTTQGNADGWFILIHPQLVAGAWVGF HHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHEEECC NDSRVTLRSDYWGQGAHSALPIVGDFFQRAQRSRLIDTRVKFATDQEPGWFAERSARLRA CCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH WFGNLFASSPPARPEAPVAPRGTTRRAPASAPAVPVEPSASATLAEPRDIPQPPLLQAPG HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC SAPGSAPAAASGAVDGEARGGGEPALAPTPTPDDVVPPDAGSPANALPGTSTNGGSSP CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA