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The map label for this gene is glcC [H]

Identifier: 91783597

GI number: 91783597

Start: 2466173

End: 2466940

Strand: Direct

Name: glcC [H]

Synonym: Bxe_A2218

Alternate gene names: 91783597

Gene position: 2466173-2466940 (Clockwise)

Preceding gene: 91783590

Following gene: 91783598

Centisome position: 50.37

GC content: 65.89

Gene sequence:

>768_bases
ATGCAGACAGCGGATTCGAACAACTCAAGGCAGGTCGCGGACGTGGTGGCGGAGCGTATCGAGCGGCTGATCGTCGACGG
CGTGCTGAAAACGGGGCAGGCGCTGCCGTCCGAGCGGCGCCTCACCGACAAGCTCGGCGTCTCGCGCACGGCGCTGCGTG
AAGGGCTCAAGCTGCTGCGGGCGCGCGGCATCATCGAGACTTCGCATGGCAGGGGTTCGTTCGTCGCGAGCCTCAGCGCG
CAGCCGGCCCTCACGCCGCTAATGCATCTGCTCGGTTCGCAACCGCGCACGCTCTACGATCTGTTCGAGGTGCGCGCGCT
GCTGGAAGCGGAATCCGCACGGCTCGCCGCGCTGCGCGGCACGCCCGCCGACTTCGTGCTGATCACGCGCCGCTATGAGG
AGATGATCGCGGCCCAGGGCACCGAAACGAGTGCTTCGACGCATGCGCGGCTCGACCACGCATTTCACCTGGCGATCTGC
GAGGCCTCGCATAACCCGGTGCTGGTGCACACCTTGAGCTCGCTGACCGACCTGCTGCTGAGCTCGGTGTTCGCGTCCGT
GAACAATCTCTATCACCGTGCGCCGCAAAAGCGGGTGATCGACCGTCAGCACGCTCGGCTCTATAACGCCGTTACCGGCA
AGCTGCCCGAACAGGCGCGCAAGGCGGCGGCGGATCACATCGAGAGCGTGTGCGCGAATCTGCGCGAAATCGAGCAGGAA
GAGCAGCGGCTGGTACGCGCGACATTACGGCTGGAAGGATGGGAGTAG

Upstream 100 bases:

>100_bases
CCCATTTCATGAAAAGCATTGATAGCTATGGCCCGTATCCTGCCTGTCCGGGTCGTGCGTGTTAGCATCTCATAGTGGTC
GTACCAGTTGGAAGTGAGCG

Downstream 100 bases:

>100_bases
AGGGCTTTACAATCGGGCCTTAAACATAACAATTCGCACGCTCCCCGCGTGCCCCCCACTTCATGGCGACCATCAGCGAG
CTCTTTGTCTATCCGATCAA

Product: DNA-binding transcriptional regulator GlcC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MQTADSNNSRQVADVVAERIERLIVDGVLKTGQALPSERRLTDKLGVSRTALREGLKLLRARGIIETSHGRGSFVASLSA
QPALTPLMHLLGSQPRTLYDLFEVRALLEAESARLAALRGTPADFVLITRRYEEMIAAQGTETSASTHARLDHAFHLAIC
EASHNPVLVHTLSSLTDLLLSSVFASVNNLYHRAPQKRVIDRQHARLYNAVTGKLPEQARKAAADHIESVCANLREIEQE
EQRLVRATLRLEGWE

Sequences:

>Translated_255_residues
MQTADSNNSRQVADVVAERIERLIVDGVLKTGQALPSERRLTDKLGVSRTALREGLKLLRARGIIETSHGRGSFVASLSA
QPALTPLMHLLGSQPRTLYDLFEVRALLEAESARLAALRGTPADFVLITRRYEEMIAAQGTETSASTHARLDHAFHLAIC
EASHNPVLVHTLSSLTDLLLSSVFASVNNLYHRAPQKRVIDRQHARLYNAVTGKLPEQARKAAADHIESVCANLREIEQE
EQRLVRATLRLEGWE
>Mature_255_residues
MQTADSNNSRQVADVVAERIERLIVDGVLKTGQALPSERRLTDKLGVSRTALREGLKLLRARGIIETSHGRGSFVASLSA
QPALTPLMHLLGSQPRTLYDLFEVRALLEAESARLAALRGTPADFVLITRRYEEMIAAQGTETSASTHARLDHAFHLAIC
EASHNPVLVHTLSSLTDLLLSSVFASVNNLYHRAPQKRVIDRQHARLYNAVTGKLPEQARKAAADHIESVCANLREIEQE
EQRLVRATLRLEGWE

Specific function: Activator for the glycolate oxidation locus [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789353, Length=245, Percent_Identity=64.4897959183673, Blast_Score=306, Evalue=6e-85,
Organism=Escherichia coli, GI1790032, Length=248, Percent_Identity=34.6774193548387, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1786303, Length=218, Percent_Identity=34.4036697247706, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI48994955, Length=218, Percent_Identity=31.651376146789, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790780, Length=157, Percent_Identity=33.7579617834395, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789621, Length=233, Percent_Identity=25.3218884120172, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082208, Length=229, Percent_Identity=27.0742358078603, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28235; Mature: 28235

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTADSNNSRQVADVVAERIERLIVDGVLKTGQALPSERRLTDKLGVSRTALREGLKLLR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHH
ARGIIETSHGRGSFVASLSAQPALTPLMHLLGSQPRTLYDLFEVRALLEAESARLAALRG
HHCCEECCCCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TPADFVLITRRYEEMIAAQGTETSASTHARLDHAFHLAICEASHNPVLVHTLSSLTDLLL
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCCEEHHHHHHHHHHHH
SSVFASVNNLYHRAPQKRVIDRQHARLYNAVTGKLPEQARKAAADHIESVCANLREIEQE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EQRLVRATLRLEGWE
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MQTADSNNSRQVADVVAERIERLIVDGVLKTGQALPSERRLTDKLGVSRTALREGLKLLR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHH
ARGIIETSHGRGSFVASLSAQPALTPLMHLLGSQPRTLYDLFEVRALLEAESARLAALRG
HHCCEECCCCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TPADFVLITRRYEEMIAAQGTETSASTHARLDHAFHLAICEASHNPVLVHTLSSLTDLLL
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCCEEHHHHHHHHHHHH
SSVFASVNNLYHRAPQKRVIDRQHARLYNAVTGKLPEQARKAAADHIESVCANLREIEQE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EQRLVRATLRLEGWE
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]