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The map label for this gene is ppiD [H]

Identifier: 91783524

GI number: 91783524

Start: 2379123

End: 2381060

Strand: Direct

Name: ppiD [H]

Synonym: Bxe_A2291

Alternate gene names: 91783524

Gene position: 2379123-2381060 (Clockwise)

Preceding gene: 91783523

Following gene: 91783527

Centisome position: 48.59

GC content: 62.13

Gene sequence:

>1938_bases
ATGCTCGATTTTTTCCGCAATCACAAACGCCTGATGATGTTCATGCTCATCCTCGTCATTGTGCCGGGGTTGGGTTTTGT
GGGTATTCAGGGCTTCCGCGGCTTCTTTGACGAAAGTGCAAACGTCGCGAGCGTCAACGGTCACAAGATCACTCGCGCAG
AATACGACGACGCAATGCGTCAGCAGCTCGACCGCGCCCGTCAGATGCTCGGCGCGCAGTTCGACATGAAGTCGTTCGAC
ACGCCGGAGCGCCGTAGCCAGATGCTCGACGGTCTGATCGAGCAACGCGTGCTGGCCGACGAAACACAGCGCCTGCATCT
GACCGCTTCCGACGACGCCGTGCGCCGCGTGCTGCTCAACGATCCGGTGATCTCGTCGCTGAAGAATCCTGACGGCACGA
TCGACGTCGACCGTTACAAGCAGTTGCTCGCCATGCAGGGCATGACGCCCGACCAGTACGACGAACGCGTGCGCTACAGC
ATCGCCACGCAGCAGTTGCCGGCCAGCATTCAAGGTAGCGCGTTCACGTCGAAGACCCTCGCGCAGCATCTGACCGAGCT
CGCTGAACAGCAGCGCGAAGTGCAGGGCATCGCGTTCCATCCGCGCGACTACGCGGCAAAGGTGCAGCCCACGGACGCGC
AACTGCAAGCGTATTACGACGCGCATCGCAACGACTTCGCCACGCCGGCTACCGCAACGATCCAGTATCTCGTGATGTCG
CCGGCAACGCTCGCCGCTTCCGTGCAGCCTGGCGACGCCGATCTGAAAAAGTACTACGACGACAACATCGCGCACTACCG
CGTCGAGGGTCAGGTGCGTGCGAGCCACATCCTGATCGCGGCGCCGAAAGACGCGAGCGCGGCCGACAAGGCCAAGGCGA
AGCAGAAGGCCGAGGAATTGCTCGCACAGATCAAGGCACATCCGGATCAGTTCGCGCAGATCGCGCAGCAGAATTCGCAG
GATCCGGGTTCGGCCTCGAAGGGCGGCGATCTGGGTTACTTCGGCCGCGGCATGATCGCAGGCGGCCAGGCGTTCGACGA
CGCGGTGTTCGCATTGAAGAAAGACGAAGTCAGCGGCATCGTGCAGACCGACTTCGGCTATCACATCGTCAAGGTGACGG
ACGTGAAGCCGGCCGTCACGAAGCCGTTCGACGAAGTGAAAGATCAGATCTCGAAAGACCTGAAGACGCAGTTGGCAAGC
AAGGCTTTCACCGACGATTCGGAAGGCTTCACATCGATCGTCTACGAAAAGGCGAAGAGCCTTCAGCCGGCTGCCGACAA
GTACAAGCTGCAATTGCAGACCGCCACGGTCACGCCGCAGCCGGACCCGAAGCTCGCGCCTGACAGCCCGCTGAACAACG
CCAAGTTTCTCGCCGCGGTGTTCGCGAGCGACGCGGTGACGGCTCACAACAACACGCAGGCTATCGACGTCGGCGGTAAC
ACGTTGATCGCGGCCCGCGTGATCGACTACAAGGCCGCAGCCGTGCCGTCGCTCGACGCCGTCAAGGACGCCGTACGGCA
GAAGGTCATCGCGGTTCAATCGGACGAAGCGGCTCACAAAGACGGCGCCGCCAAACTCGCCGAGTTCGAAAAGTCGAAGT
CGACCGCAGGCTTCTCCTCGCCGCTGAAGGTATCGCGTAACGACGCGCAGGGCGTGCCGCCGGCCGCATTGAGTGCAATC
TACAAGGTGGACGCGCAGAAATTGCCGGCCTATGTCGGCGTGGACCTCGGTGACGACGGCTATGCGATCTATCGCGTGAA
CGCGGTGGTGGCAGGCGCGGCGGTGGATCCGCAGCGTCTGGCCGCTGCGCAGCAGCAGATCGCGCAGGTCGATGCGCAGT
CCGAAGCAGAGGCGTATCTCCAGGCGCTGCGCGCGCGTTCGAAGGTGAAGTTCTATGGCTCGCTCGATAGCAGCAACGCG
CAGGCGAGCAGCGAGTAA

Upstream 100 bases:

>100_bases
CGTCCACTCCGCCAGTATCCTCGAAAGGCGAACTCCGGTTCGCCTTTTTTGTTGCCCGCTGTTGTAAGATCGGGCGTTCT
GTTTTTGGCACTCCTCACGC

Downstream 100 bases:

>100_bases
AATCGCGCAAACGCAAAAAAGCCCCGCAAATTGCGGGGCTTTTTACATTTGACGAGTGCAAGCTCGTCAAACGGCTTGCC
GCAGCGCGTTACAGGCAGCC

Product: putative PpiC-type peptidyl-prolyl cis- trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MLDFFRNHKRLMMFMLILVIVPGLGFVGIQGFRGFFDESANVASVNGHKITRAEYDDAMRQQLDRARQMLGAQFDMKSFD
TPERRSQMLDGLIEQRVLADETQRLHLTASDDAVRRVLLNDPVISSLKNPDGTIDVDRYKQLLAMQGMTPDQYDERVRYS
IATQQLPASIQGSAFTSKTLAQHLTELAEQQREVQGIAFHPRDYAAKVQPTDAQLQAYYDAHRNDFATPATATIQYLVMS
PATLAASVQPGDADLKKYYDDNIAHYRVEGQVRASHILIAAPKDASAADKAKAKQKAEELLAQIKAHPDQFAQIAQQNSQ
DPGSASKGGDLGYFGRGMIAGGQAFDDAVFALKKDEVSGIVQTDFGYHIVKVTDVKPAVTKPFDEVKDQISKDLKTQLAS
KAFTDDSEGFTSIVYEKAKSLQPAADKYKLQLQTATVTPQPDPKLAPDSPLNNAKFLAAVFASDAVTAHNNTQAIDVGGN
TLIAARVIDYKAAAVPSLDAVKDAVRQKVIAVQSDEAAHKDGAAKLAEFEKSKSTAGFSSPLKVSRNDAQGVPPAALSAI
YKVDAQKLPAYVGVDLGDDGYAIYRVNAVVAGAAVDPQRLAAAQQQIAQVDAQSEAEAYLQALRARSKVKFYGSLDSSNA
QASSE

Sequences:

>Translated_645_residues
MLDFFRNHKRLMMFMLILVIVPGLGFVGIQGFRGFFDESANVASVNGHKITRAEYDDAMRQQLDRARQMLGAQFDMKSFD
TPERRSQMLDGLIEQRVLADETQRLHLTASDDAVRRVLLNDPVISSLKNPDGTIDVDRYKQLLAMQGMTPDQYDERVRYS
IATQQLPASIQGSAFTSKTLAQHLTELAEQQREVQGIAFHPRDYAAKVQPTDAQLQAYYDAHRNDFATPATATIQYLVMS
PATLAASVQPGDADLKKYYDDNIAHYRVEGQVRASHILIAAPKDASAADKAKAKQKAEELLAQIKAHPDQFAQIAQQNSQ
DPGSASKGGDLGYFGRGMIAGGQAFDDAVFALKKDEVSGIVQTDFGYHIVKVTDVKPAVTKPFDEVKDQISKDLKTQLAS
KAFTDDSEGFTSIVYEKAKSLQPAADKYKLQLQTATVTPQPDPKLAPDSPLNNAKFLAAVFASDAVTAHNNTQAIDVGGN
TLIAARVIDYKAAAVPSLDAVKDAVRQKVIAVQSDEAAHKDGAAKLAEFEKSKSTAGFSSPLKVSRNDAQGVPPAALSAI
YKVDAQKLPAYVGVDLGDDGYAIYRVNAVVAGAAVDPQRLAAAQQQIAQVDAQSEAEAYLQALRARSKVKFYGSLDSSNA
QASSE
>Mature_645_residues
MLDFFRNHKRLMMFMLILVIVPGLGFVGIQGFRGFFDESANVASVNGHKITRAEYDDAMRQQLDRARQMLGAQFDMKSFD
TPERRSQMLDGLIEQRVLADETQRLHLTASDDAVRRVLLNDPVISSLKNPDGTIDVDRYKQLLAMQGMTPDQYDERVRYS
IATQQLPASIQGSAFTSKTLAQHLTELAEQQREVQGIAFHPRDYAAKVQPTDAQLQAYYDAHRNDFATPATATIQYLVMS
PATLAASVQPGDADLKKYYDDNIAHYRVEGQVRASHILIAAPKDASAADKAKAKQKAEELLAQIKAHPDQFAQIAQQNSQ
DPGSASKGGDLGYFGRGMIAGGQAFDDAVFALKKDEVSGIVQTDFGYHIVKVTDVKPAVTKPFDEVKDQISKDLKTQLAS
KAFTDDSEGFTSIVYEKAKSLQPAADKYKLQLQTATVTPQPDPKLAPDSPLNNAKFLAAVFASDAVTAHNNTQAIDVGGN
TLIAARVIDYKAAAVPSLDAVKDAVRQKVIAVQSDEAAHKDGAAKLAEFEKSKSTAGFSSPLKVSRNDAQGVPPAALSAI
YKVDAQKLPAYVGVDLGDDGYAIYRVNAVVAGAAVDPQRLAAAQQQIAQVDAQSEAEAYLQALRARSKVKFYGSLDSSNA
QASSE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=655, Percent_Identity=26.1068702290076, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1786238, Length=106, Percent_Identity=36.7924528301887, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 70008; Mature: 70008

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFFRNHKRLMMFMLILVIVPGLGFVGIQGFRGFFDESANVASVNGHKITRAEYDDAMR
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCEEEHHHHHHHHH
QQLDRARQMLGAQFDMKSFDTPERRSQMLDGLIEQRVLADETQRLHLTASDDAVRRVLLN
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHC
DPVISSLKNPDGTIDVDRYKQLLAMQGMTPDQYDERVRYSIATQQLPASIQGSAFTSKTL
CHHHHHCCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AQHLTELAEQQREVQGIAFHPRDYAAKVQPTDAQLQAYYDAHRNDFATPATATIQYLVMS
HHHHHHHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHEEC
PATLAASVQPGDADLKKYYDDNIAHYRVEGQVRASHILIAAPKDASAADKAKAKQKAEEL
CHHHEEECCCCCHHHHHHHCCCCEEEEEECEEEEEEEEEECCCCCCHHHHHHHHHHHHHH
LAQIKAHPDQFAQIAQQNSQDPGSASKGGDLGYFGRGMIAGGQAFDDAVFALKKDEVSGI
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHEEHHHHCCE
VQTDFGYHIVKVTDVKPAVTKPFDEVKDQISKDLKTQLASKAFTDDSEGFTSIVYEKAKS
EEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
LQPAADKYKLQLQTATVTPQPDPKLAPDSPLNNAKFLAAVFASDAVTAHNNTQAIDVGGN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCEEEECCCC
TLIAARVIDYKAAAVPSLDAVKDAVRQKVIAVQSDEAAHKDGAAKLAEFEKSKSTAGFSS
EEEEEEEHHHHHHCCCCHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHCCCCCCCC
PLKVSRNDAQGVPPAALSAIYKVDAQKLPAYVGVDLGDDGYAIYRVNAVVAGAAVDPQRL
CCEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEEEEEECCCCCHHHH
AAAQQQIAQVDAQSEAEAYLQALRARSKVKFYGSLDSSNAQASSE
HHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MLDFFRNHKRLMMFMLILVIVPGLGFVGIQGFRGFFDESANVASVNGHKITRAEYDDAMR
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCEEEHHHHHHHHH
QQLDRARQMLGAQFDMKSFDTPERRSQMLDGLIEQRVLADETQRLHLTASDDAVRRVLLN
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHC
DPVISSLKNPDGTIDVDRYKQLLAMQGMTPDQYDERVRYSIATQQLPASIQGSAFTSKTL
CHHHHHCCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AQHLTELAEQQREVQGIAFHPRDYAAKVQPTDAQLQAYYDAHRNDFATPATATIQYLVMS
HHHHHHHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHEEC
PATLAASVQPGDADLKKYYDDNIAHYRVEGQVRASHILIAAPKDASAADKAKAKQKAEEL
CHHHEEECCCCCHHHHHHHCCCCEEEEEECEEEEEEEEEECCCCCCHHHHHHHHHHHHHH
LAQIKAHPDQFAQIAQQNSQDPGSASKGGDLGYFGRGMIAGGQAFDDAVFALKKDEVSGI
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHEEHHHHCCE
VQTDFGYHIVKVTDVKPAVTKPFDEVKDQISKDLKTQLASKAFTDDSEGFTSIVYEKAKS
EEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
LQPAADKYKLQLQTATVTPQPDPKLAPDSPLNNAKFLAAVFASDAVTAHNNTQAIDVGGN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCEEEECCCC
TLIAARVIDYKAAAVPSLDAVKDAVRQKVIAVQSDEAAHKDGAAKLAEFEKSKSTAGFSS
EEEEEEEHHHHHHCCCCHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHCCCCCCCC
PLKVSRNDAQGVPPAALSAIYKVDAQKLPAYVGVDLGDDGYAIYRVNAVVAGAAVDPQRL
CCEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEEEEEECCCCCHHHH
AAAQQQIAQVDAQSEAEAYLQALRARSKVKFYGSLDSSNAQASSE
HHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]